PMC:7074654 / 7434-8475 JSONTXT

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T31","span":{"begin":608,"end":609},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"Our review found the average R0 to be 3.28 and median to be 2.79, which exceed WHO estimates from 1.4 to 2.5. The studies using stochastic and statistical methods for deriving R0 provide estimates that are reasonably comparable. However, the studies using mathematical methods produce estimates that are, on average, higher. Some of the mathematically derived estimates fall within the range produced the statistical and stochastic estimates. It is important to further assess the reason for the higher R0 values estimated by some the mathematical studies. For example, modelling assumptions may have played a role. In more recent studies, R0 seems to have stabilized at around 2–3. R0 estimations produced at later stages can be expected to be more reliable, as they build upon more case data and include the effect of awareness and intervention. It is worthy to note that the WHO point estimates are consistently below all published estimates, although the higher end of the WHO range includes the lower end of the estimates reviewed here."}

{"project":"LitCovid-sentences","denotations":[{"id":"T39","span":{"begin":0,"end":109},"obj":"Sentence"},{"id":"T40","span":{"begin":110,"end":228},"obj":"Sentence"},{"id":"T41","span":{"begin":229,"end":324},"obj":"Sentence"},{"id":"T42","span":{"begin":325,"end":442},"obj":"Sentence"},{"id":"T43","span":{"begin":443,"end":556},"obj":"Sentence"},{"id":"T44","span":{"begin":557,"end":615},"obj":"Sentence"},{"id":"T45","span":{"begin":616,"end":682},"obj":"Sentence"},{"id":"T46","span":{"begin":683,"end":847},"obj":"Sentence"},{"id":"T47","span":{"begin":848,"end":1041},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Our review found the average R0 to be 3.28 and median to be 2.79, which exceed WHO estimates from 1.4 to 2.5. The studies using stochastic and statistical methods for deriving R0 provide estimates that are reasonably comparable. However, the studies using mathematical methods produce estimates that are, on average, higher. Some of the mathematically derived estimates fall within the range produced the statistical and stochastic estimates. It is important to further assess the reason for the higher R0 values estimated by some the mathematical studies. For example, modelling assumptions may have played a role. In more recent studies, R0 seems to have stabilized at around 2–3. R0 estimations produced at later stages can be expected to be more reliable, as they build upon more case data and include the effect of awareness and intervention. It is worthy to note that the WHO point estimates are consistently below all published estimates, although the higher end of the WHO range includes the lower end of the estimates reviewed here."}