PMC:7074453 / 9852-12117 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7074453","sourcedb":"PMC","sourceid":"7074453","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7074453","text":"4.3. Chest Imaging\nAll patients suffered from pneumonia, and chest CT scans showed shadows in the lung [20]. In the early stages of the disease, patients present with multiple small patch shadows and interstitial changes, especially in the extrapulmonary zone. It further progresses to multiple ground glass shadows and infiltrative shadows in both lungs. In severe cases, lung consolidation may occur, but pleural effusion is rare [20].\nTo provide more information about the disease for the treatment in clinics, we collected detailed information about the fatal cases released by official channels. A total of 41 fatal cases were used to reveal the symptoms of the deaths, showing the symptom composition of fever (80.5%), cough (56.1%), short of breath (31.7%), chest tightness/pain (24.4%), fatigue (22.0%), dyspnea (12.2%), dizziness/headache (4.9%), general pain (7.3%) and chills (4.9%) (Figure 2). A total of 26 cases with fatalities were used to disclose the dangerous comorbidities, showing that the major comorbidities are hypertension (53.8%), diabetes (42.3%), coronary heart disease (19.2%), cerebral infarction (15.4%), chronic bronchitis (19.2%) and Parkinson’s disease (7.7%) (Figure 2). Chen N et al. reported that, among 99 confirmed cases, the common symptoms are fever (83%), cough (82%), bilateral pneumonia (75%), short of breath (31%), muscle ache (11%), confusion (9%), headache (8%), sore throat (5%), rhinorrhoea (4%), chest pain (2%), diarrhoea (2%), and nausea and vomiting (1%) [4]. Huang C et al. reported that, among 41 confirmed cases, the symptom composition is as follows: pneumonia (100%), fever (98%), cough (76%), lymphopenia (63%), Dyspnea (55%), fatigue (44%), sputum production (28%), headache (8%), hemoptysis (5%), and diarrhea (3%); and the underlying diseases included diabetes (20%), hypertension (15%), and cardiovascular disease (15%) [21]. Though the symptom compositions reported for the confirmed cases are similar to that of the fatality cases we collected, the percentages of hypertension, diabetes, and coronary heart diseases are much higher among the fatality cases than among the confirmed cases. This may indicate that the comorbidities probably are important factors resulted in death of COVID-19 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