PMC:7074453 / 8104-9153
Annnotations
{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7074453","sourcedb":"PMC","sourceid":"7074453","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7074453","text":"4.1. Clinical Manifestations\nAccording to the “Diagnosis \u0026 Treatment Scheme for Novel Coronavirus Pneumonia (Trial) 6th Edition” enacted by the National Health Commission of the People’s Republic of China on 19 February 2020, the incubation time after exposure is about 1–14 days [20]. Fever, fatigue, and a dry cough are the main manifestations. Nasal obstruction, runny nose, and other upper respiratory symptoms are rare. About half of the patients developed dyspnea one week later, and severe cases developed rapidly into acute respiratory distress syndrome, septic shock, hard-to-correct metabolic acidosis, and coagulation dysfunction. Severe and critical patients may present moderate to low fever, or even no obvious fever. Some patients have mild onset symptoms, no fever, and mostly recovered after one week. Most patients have a favorable prognosis, although some patients are left in a critical condition, or do not survive. The aged patients and the patients with basic diseases have worse prognosis. Children cases are relatively 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