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LitCovid-PubTator

LitCovid-PD-FMA-UBERON

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T3","span":{"begin":85,"end":88},"obj":"Body_part"},{"id":"T4","span":{"begin":247,"end":253},"obj":"Body_part"},{"id":"T5","span":{"begin":644,"end":667},"obj":"Body_part"},{"id":"T6","span":{"begin":997,"end":1003},"obj":"Body_part"},{"id":"T7","span":{"begin":1482,"end":1489},"obj":"Body_part"},{"id":"T8","span":{"begin":1592,"end":1600},"obj":"Body_part"},{"id":"T9","span":{"begin":1621,"end":1628},"obj":"Body_part"},{"id":"T10","span":{"begin":1629,"end":1633},"obj":"Body_part"},{"id":"T11","span":{"begin":1717,"end":1724},"obj":"Body_part"},{"id":"T12","span":{"begin":1914,"end":1921},"obj":"Body_part"}],"attributes":[{"id":"A3","pred":"fma_id","subj":"T3","obj":"http://purl.org/sig/ont/fma/fma67095"},{"id":"A4","pred":"fma_id","subj":"T4","obj":"http://purl.org/sig/ont/fma/fma84116"},{"id":"A5","pred":"fma_id","subj":"T5","obj":"http://purl.org/sig/ont/fma/fma45662"},{"id":"A6","pred":"fma_id","subj":"T6","obj":"http://purl.org/sig/ont/fma/fma84116"},{"id":"A7","pred":"fma_id","subj":"T7","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A8","pred":"fma_id","subj":"T8","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A9","pred":"fma_id","subj":"T9","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A10","pred":"fma_id","subj":"T10","obj":"http://purl.org/sig/ont/fma/fma74402"},{"id":"A11","pred":"fma_id","subj":"T11","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A12","pred":"fma_id","subj":"T12","obj":"http://purl.org/sig/ont/fma/fma67257"}],"text":"3. Pathogenic Characteristics of Coronavirus\nCoronavirus is a single strand positive RNA (+ssRNA) virus, belonging to order Nidovirales, family Coronaviridae, and subfamily Orthocoronavirinae [13]. According to the characteristics of serotype and genome, the coronavirus subfamily is divided into four genera: α, β, γ, and δ [14]. There are six kinds of coronaviruses known to infect humans, including 229E and NL63 of α genus [15,16], OC43, HKU1, Middle East respiratory syndrome-associated coronavirus (MERSr-CoV), and severe acute respiratory syndrome-associated coronavirus (SARSr-CoV) of β genus [16,17]. The coronavirus isolated from the lower respiratory tract of patients with unidentified pneumonia in Wuhan is a new type of coronavirus (SARS-CoV-2) belonging to genus β, and subgenus sarbe [5]. SARS-CoV-2 is different from the zoonotic MERSr-CoV and SARSr-CoV and becomes the seventh coronavirus to infect humans [5]. The phylogenetic analysis of the coronaviruses based on full-length genome sequences shows that SARS-CoV-2 has the smallest genetic distance from bat coronavirus, but only about 45%–90% similarity with SARSr-CoV, and a lower similarity of 20%–60% with MERSr-CoV [18]. Therefore, a bat is probably the original host of SARS-CoV-2, although the intermediate host may still exist in the process of transmission from bats to human beings.\nCoronavirus has an envelope, the particles are round or oval, often pleomorphic, with a diameter of 50–200 nm [18]. S protein is located on the surface of the virus and forms a rod-shaped structure. As one of the main antigenic proteins of the virus, the S protein gene is the main target used for typing [19]. Xu et al. also reported that SARS-CoV-2 S-protein supports a strong interaction with human angiotensin-converting enzyme 2 (ACE2) molecules, which means that the virus poses a significant public health risk for human transmission by the S-protein–ACE2 binding pathway [18].\nThe knowledge of the physical and chemical characteristics of coronaviruses mostly comes from the study of SARS-CoV and MERS-CoV. The coronaviruses are sensitive to heat and can be killed at 56 °C for 30 min. In addition, ether, 75% ethanol, chlorine disinfectant, peracetic acid, and chloroform can effectively inactivate the virus, but not chlorhexidine [20]."}

LitCovid-PD-UBERON

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T3","span":{"begin":644,"end":667},"obj":"Body_part"},{"id":"T4","span":{"begin":650,"end":667},"obj":"Body_part"}],"attributes":[{"id":"A3","pred":"uberon_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/UBERON_0001558"},{"id":"A4","pred":"uberon_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/UBERON_0000065"}],"text":"3. Pathogenic Characteristics of Coronavirus\nCoronavirus is a single strand positive RNA (+ssRNA) virus, belonging to order Nidovirales, family Coronaviridae, and subfamily Orthocoronavirinae [13]. According to the characteristics of serotype and genome, the coronavirus subfamily is divided into four genera: α, β, γ, and δ [14]. There are six kinds of coronaviruses known to infect humans, including 229E and NL63 of α genus [15,16], OC43, HKU1, Middle East respiratory syndrome-associated coronavirus (MERSr-CoV), and severe acute respiratory syndrome-associated coronavirus (SARSr-CoV) of β genus [16,17]. The coronavirus isolated from the lower respiratory tract of patients with unidentified pneumonia in Wuhan is a new type of coronavirus (SARS-CoV-2) belonging to genus β, and subgenus sarbe [5]. SARS-CoV-2 is different from the zoonotic MERSr-CoV and SARSr-CoV and becomes the seventh coronavirus to infect humans [5]. The phylogenetic analysis of the coronaviruses based on full-length genome sequences shows that SARS-CoV-2 has the smallest genetic distance from bat coronavirus, but only about 45%–90% similarity with SARSr-CoV, and a lower similarity of 20%–60% with MERSr-CoV [18]. Therefore, a bat is probably the original host of SARS-CoV-2, although the intermediate host may still exist in the process of transmission from bats to human beings.\nCoronavirus has an envelope, the particles are round or oval, often pleomorphic, with a diameter of 50–200 nm [18]. S protein is located on the surface of the virus and forms a rod-shaped structure. As one of the main antigenic proteins of the virus, the S protein gene is the main target used for typing [19]. Xu et al. also reported that SARS-CoV-2 S-protein supports a strong interaction with human angiotensin-converting enzyme 2 (ACE2) molecules, which means that the virus poses a significant public health risk for human transmission by the S-protein–ACE2 binding pathway [18].\nThe knowledge of the physical and chemical characteristics of coronaviruses mostly comes from the study of SARS-CoV and MERS-CoV. The coronaviruses are sensitive to heat and can be killed at 56 °C for 30 min. In addition, ether, 75% ethanol, chlorine disinfectant, peracetic acid, and chloroform can effectively inactivate the virus, but not chlorhexidine [20]."}

LitCovid-PD-MONDO

LitCovid-PD-CLO

LitCovid-PD-CHEBI

LitCovid-sentences

{"project":"LitCovid-sentences","denotations":[{"id":"T43","span":{"begin":0,"end":2},"obj":"Sentence"},{"id":"T44","span":{"begin":3,"end":44},"obj":"Sentence"},{"id":"T45","span":{"begin":45,"end":197},"obj":"Sentence"},{"id":"T46","span":{"begin":198,"end":330},"obj":"Sentence"},{"id":"T47","span":{"begin":331,"end":609},"obj":"Sentence"},{"id":"T48","span":{"begin":610,"end":804},"obj":"Sentence"},{"id":"T49","span":{"begin":805,"end":928},"obj":"Sentence"},{"id":"T50","span":{"begin":929,"end":1196},"obj":"Sentence"},{"id":"T51","span":{"begin":1197,"end":1363},"obj":"Sentence"},{"id":"T52","span":{"begin":1364,"end":1479},"obj":"Sentence"},{"id":"T53","span":{"begin":1480,"end":1562},"obj":"Sentence"},{"id":"T54","span":{"begin":1563,"end":1674},"obj":"Sentence"},{"id":"T55","span":{"begin":1675,"end":1948},"obj":"Sentence"},{"id":"T56","span":{"begin":1949,"end":2078},"obj":"Sentence"},{"id":"T57","span":{"begin":2079,"end":2157},"obj":"Sentence"},{"id":"T58","span":{"begin":2158,"end":2310},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"3. Pathogenic Characteristics of Coronavirus\nCoronavirus is a single strand positive RNA (+ssRNA) virus, belonging to order Nidovirales, family Coronaviridae, and subfamily Orthocoronavirinae [13]. According to the characteristics of serotype and genome, the coronavirus subfamily is divided into four genera: α, β, γ, and δ [14]. There are six kinds of coronaviruses known to infect humans, including 229E and NL63 of α genus [15,16], OC43, HKU1, Middle East respiratory syndrome-associated coronavirus (MERSr-CoV), and severe acute respiratory syndrome-associated coronavirus (SARSr-CoV) of β genus [16,17]. The coronavirus isolated from the lower respiratory tract of patients with unidentified pneumonia in Wuhan is a new type of coronavirus (SARS-CoV-2) belonging to genus β, and subgenus sarbe [5]. SARS-CoV-2 is different from the zoonotic MERSr-CoV and SARSr-CoV and becomes the seventh coronavirus to infect humans [5]. The phylogenetic analysis of the coronaviruses based on full-length genome sequences shows that SARS-CoV-2 has the smallest genetic distance from bat coronavirus, but only about 45%–90% similarity with SARSr-CoV, and a lower similarity of 20%–60% with MERSr-CoV [18]. Therefore, a bat is probably the original host of SARS-CoV-2, although the intermediate host may still exist in the process of transmission from bats to human beings.\nCoronavirus has an envelope, the particles are round or oval, often pleomorphic, with a diameter of 50–200 nm [18]. S protein is located on the surface of the virus and forms a rod-shaped structure. As one of the main antigenic proteins of the virus, the S protein gene is the main target used for typing [19]. Xu et al. also reported that SARS-CoV-2 S-protein supports a strong interaction with human angiotensin-converting enzyme 2 (ACE2) molecules, which means that the virus poses a significant public health risk for human transmission by the S-protein–ACE2 binding pathway [18].\nThe knowledge of the physical and chemical characteristics of coronaviruses mostly comes from the study of SARS-CoV and MERS-CoV. The coronaviruses are sensitive to heat and can be killed at 56 °C for 30 min. In addition, ether, 75% ethanol, chlorine disinfectant, peracetic acid, and chloroform can effectively inactivate the virus, but not chlorhexidine [20]."}

LitCovid-PD-HP

{"project":"LitCovid-PD-HP","denotations":[{"id":"T17","span":{"begin":698,"end":707},"obj":"Phenotype"}],"attributes":[{"id":"A17","pred":"hp_id","subj":"T17","obj":"http://purl.obolibrary.org/obo/HP_0002090"}],"text":"3. Pathogenic Characteristics of Coronavirus\nCoronavirus is a single strand positive RNA (+ssRNA) virus, belonging to order Nidovirales, family Coronaviridae, and subfamily Orthocoronavirinae [13]. According to the characteristics of serotype and genome, the coronavirus subfamily is divided into four genera: α, β, γ, and δ [14]. There are six kinds of coronaviruses known to infect humans, including 229E and NL63 of α genus [15,16], OC43, HKU1, Middle East respiratory syndrome-associated coronavirus (MERSr-CoV), and severe acute respiratory syndrome-associated coronavirus (SARSr-CoV) of β genus [16,17]. The coronavirus isolated from the lower respiratory tract of patients with unidentified pneumonia in Wuhan is a new type of coronavirus (SARS-CoV-2) belonging to genus β, and subgenus sarbe [5]. SARS-CoV-2 is different from the zoonotic MERSr-CoV and SARSr-CoV and becomes the seventh coronavirus to infect humans [5]. The phylogenetic analysis of the coronaviruses based on full-length genome sequences shows that SARS-CoV-2 has the smallest genetic distance from bat coronavirus, but only about 45%–90% similarity with SARSr-CoV, and a lower similarity of 20%–60% with MERSr-CoV [18]. Therefore, a bat is probably the original host of SARS-CoV-2, although the intermediate host may still exist in the process of transmission from bats to human beings.\nCoronavirus has an envelope, the particles are round or oval, often pleomorphic, with a diameter of 50–200 nm [18]. S protein is located on the surface of the virus and forms a rod-shaped structure. As one of the main antigenic proteins of the virus, the S protein gene is the main target used for typing [19]. Xu et al. also reported that SARS-CoV-2 S-protein supports a strong interaction with human angiotensin-converting enzyme 2 (ACE2) molecules, which means that the virus poses a significant public health risk for human transmission by the S-protein–ACE2 binding pathway [18].\nThe knowledge of the physical and chemical characteristics of coronaviruses mostly comes from the study of SARS-CoV and MERS-CoV. The coronaviruses are sensitive to heat and can be killed at 56 °C for 30 min. In addition, ether, 75% ethanol, chlorine disinfectant, peracetic acid, and chloroform can effectively inactivate the virus, but not chlorhexidine [20]."}

2_test

{"project":"2_test","denotations":[{"id":"32093211-30531947-57901186","span":{"begin":193,"end":195},"obj":"30531947"},{"id":"32093211-30791586-57901187","span":{"begin":326,"end":328},"obj":"30791586"},{"id":"32093211-9367365-57901188","span":{"begin":428,"end":430},"obj":"9367365"},{"id":"32093211-17631932-57901189","span":{"begin":431,"end":433},"obj":"17631932"},{"id":"32093211-17631932-57901190","span":{"begin":602,"end":604},"obj":"17631932"},{"id":"32093211-30679277-57901191","span":{"begin":605,"end":607},"obj":"30679277"},{"id":"32093211-32009228-57901192","span":{"begin":1192,"end":1194},"obj":"32009228"},{"id":"32093211-32009228-57901193","span":{"begin":1475,"end":1477},"obj":"32009228"},{"id":"32093211-18798692-57901194","span":{"begin":1670,"end":1672},"obj":"18798692"},{"id":"32093211-32009228-57901195","span":{"begin":1944,"end":1946},"obj":"32009228"}],"text":"3. Pathogenic Characteristics of Coronavirus\nCoronavirus is a single strand positive RNA (+ssRNA) virus, belonging to order Nidovirales, family Coronaviridae, and subfamily Orthocoronavirinae [13]. According to the characteristics of serotype and genome, the coronavirus subfamily is divided into four genera: α, β, γ, and δ [14]. There are six kinds of coronaviruses known to infect humans, including 229E and NL63 of α genus [15,16], OC43, HKU1, Middle East respiratory syndrome-associated coronavirus (MERSr-CoV), and severe acute respiratory syndrome-associated coronavirus (SARSr-CoV) of β genus [16,17]. The coronavirus isolated from the lower respiratory tract of patients with unidentified pneumonia in Wuhan is a new type of coronavirus (SARS-CoV-2) belonging to genus β, and subgenus sarbe [5]. SARS-CoV-2 is different from the zoonotic MERSr-CoV and SARSr-CoV and becomes the seventh coronavirus to infect humans [5]. The phylogenetic analysis of the coronaviruses based on full-length genome sequences shows that SARS-CoV-2 has the smallest genetic distance from bat coronavirus, but only about 45%–90% similarity with SARSr-CoV, and a lower similarity of 20%–60% with MERSr-CoV [18]. Therefore, a bat is probably the original host of SARS-CoV-2, although the intermediate host may still exist in the process of transmission from bats to human beings.\nCoronavirus has an envelope, the particles are round or oval, often pleomorphic, with a diameter of 50–200 nm [18]. S protein is located on the surface of the virus and forms a rod-shaped structure. As one of the main antigenic proteins of the virus, the S protein gene is the main target used for typing [19]. Xu et al. also reported that SARS-CoV-2 S-protein supports a strong interaction with human angiotensin-converting enzyme 2 (ACE2) molecules, which means that the virus poses a significant public health risk for human transmission by the S-protein–ACE2 binding pathway [18].\nThe knowledge of the physical and chemical characteristics of coronaviruses mostly comes from the study of SARS-CoV and MERS-CoV. The coronaviruses are sensitive to heat and can be killed at 56 °C for 30 min. In addition, ether, 75% ethanol, chlorine disinfectant, peracetic acid, and chloroform can effectively inactivate the virus, but not chlorhexidine [20]."}

PMC:7074453 / 5751-8061 JSONTXT

Annnotations TAB JSON ListView MergeView

PMC:7074453 / 5751-8061 JSON TXT