PMC:7074424 / 8797-9689 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"184","span":{"begin":9,"end":12},"obj":"Species"},{"id":"185","span":{"begin":181,"end":184},"obj":"Species"},{"id":"192","span":{"begin":307,"end":311},"obj":"Gene"},{"id":"193","span":{"begin":287,"end":305},"obj":"Species"},{"id":"194","span":{"begin":312,"end":315},"obj":"Species"},{"id":"195","span":{"begin":317,"end":325},"obj":"Species"},{"id":"196","span":{"begin":327,"end":336},"obj":"Species"},{"id":"197","span":{"begin":721,"end":724},"obj":"Species"}],"attributes":[{"id":"A184","pred":"tao:has_database_id","subj":"184","obj":"Tax:11118"},{"id":"A185","pred":"tao:has_database_id","subj":"185","obj":"Tax:11118"},{"id":"A192","pred":"tao:has_database_id","subj":"192","obj":"Gene:54938"},{"id":"A193","pred":"tao:has_database_id","subj":"193","obj":"Tax:2697049"},{"id":"A194","pred":"tao:has_database_id","subj":"194","obj":"Tax:11118"},{"id":"A195","pred":"tao:has_database_id","subj":"195","obj":"Tax:1335626"},{"id":"A196","pred":"tao:has_database_id","subj":"196","obj":"Tax:2697049"},{"id":"A197","pred":"tao:has_database_id","subj":"197","obj":"Tax:11118"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":" targets CoV, in this article, we have reviewed the possible protein structures, which could be potential targets for the development of a therapeutic approach for the treatment of CoV.\n\nMaterials and Methods\n\nDatabase screen\nWe screened PubMed and RCSB database with the keywords HCoV, NCoV, corona virus, SERS-CoV, MERS-CoV, 2019-nCoV, crystal structure, X-ray crystallography structure, NMR structure, target, and drug target till Feb 3, 2020. The database files were extracted using endnote, and title and abstract screening was done using Rayyan QCRI. Full texts of these screened articles were further screened for possible inclusion in the systematic review. Articles that evaluated different druggable targets of CoV and evaluated different therapeutic measures against some identifiable target were included for further review.\n\nResults and Discussion\nA total of 392 articles were fo"}

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T284","span":{"begin":293,"end":299},"obj":"NCBITaxon:11118"},{"id":"T283","span":{"begin":300,"end":305},"obj":"NCBITaxon:10239"},{"id":"T282","span":{"begin":317,"end":325},"obj":"SP_9"},{"id":"T281","span":{"begin":327,"end":336},"obj":"SP_7"},{"id":"T280","span":{"begin":417,"end":421},"obj":"CHEBI:23888;CHEBI:23888"}],"text":" targets CoV, in this article, we have reviewed the possible protein structures, which could be potential targets for the development of a therapeutic approach for the treatment of CoV.\n\nMaterials and Methods\n\nDatabase screen\nWe screened PubMed and RCSB database with the keywords HCoV, NCoV, corona virus, SERS-CoV, MERS-CoV, 2019-nCoV, crystal structure, X-ray crystallography structure, NMR structure, target, and drug target till Feb 3, 2020. The database files were extracted using endnote, and title and abstract screening was done using Rayyan QCRI. Full texts of these screened articles were further screened for possible inclusion in the systematic review. Articles that evaluated different druggable targets of CoV and evaluated different therapeutic measures against some identifiable target were included for further review.\n\nResults and Discussion\nA total of 392 articles were fo"}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T94","span":{"begin":61,"end":68},"obj":"Body_part"}],"attributes":[{"id":"A94","pred":"fma_id","subj":"T94","obj":"http://purl.org/sig/ont/fma/fma67257"}],"text":" targets CoV, in this article, we have reviewed the possible protein structures, which could be potential targets for the development of a therapeutic approach for the treatment of CoV.\n\nMaterials and Methods\n\nDatabase screen\nWe screened PubMed and RCSB database with the keywords HCoV, NCoV, corona virus, SERS-CoV, MERS-CoV, 2019-nCoV, crystal structure, X-ray crystallography structure, NMR structure, target, and drug target till Feb 3, 2020. The database files were extracted using endnote, and title and abstract screening was done using Rayyan QCRI. Full texts of these screened articles were further screened for possible inclusion in the systematic review. Articles that evaluated different druggable targets of CoV and evaluated different therapeutic measures against some identifiable target were included for further review.\n\nResults and Discussion\nA total of 392 articles were fo"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T89","span":{"begin":137,"end":138},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T90","span":{"begin":300,"end":305},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T91","span":{"begin":861,"end":862},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":" targets CoV, in this article, we have reviewed the possible protein structures, which could be potential targets for the development of a therapeutic approach for the treatment of CoV.\n\nMaterials and Methods\n\nDatabase screen\nWe screened PubMed and RCSB database with the keywords HCoV, NCoV, corona virus, SERS-CoV, MERS-CoV, 2019-nCoV, crystal structure, X-ray crystallography structure, NMR structure, target, and drug target till Feb 3, 2020. The database files were extracted using endnote, and title and abstract screening was done using Rayyan QCRI. Full texts of these screened articles were further screened for possible inclusion in the systematic review. Articles that evaluated different druggable targets of CoV and evaluated different therapeutic measures against some identifiable target were included for further review.\n\nResults and Discussion\nA total of 392 articles were fo"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T70","span":{"begin":61,"end":68},"obj":"Chemical"},{"id":"T71","span":{"begin":293,"end":299},"obj":"Chemical"},{"id":"T72","span":{"begin":417,"end":421},"obj":"Chemical"}],"attributes":[{"id":"A70","pred":"chebi_id","subj":"T70","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A71","pred":"chebi_id","subj":"T71","obj":"http://purl.obolibrary.org/obo/CHEBI_37409"},{"id":"A72","pred":"chebi_id","subj":"T72","obj":"http://purl.obolibrary.org/obo/CHEBI_23888"}],"text":" targets CoV, in this article, we have reviewed the possible protein structures, which could be potential targets for the development of a therapeutic approach for the treatment of CoV.\n\nMaterials and Methods\n\nDatabase screen\nWe screened PubMed and RCSB database with the keywords HCoV, NCoV, corona virus, SERS-CoV, MERS-CoV, 2019-nCoV, crystal structure, X-ray crystallography structure, NMR structure, target, and drug target till Feb 3, 2020. The database files were extracted using endnote, and title and abstract screening was done using Rayyan QCRI. Full texts of these screened articles were further screened for possible inclusion in the systematic review. Articles that evaluated different druggable targets of CoV and evaluated different therapeutic measures against some identifiable target were included for further review.\n\nResults and Discussion\nA total of 392 articles were fo"}

{"project":"LitCovid-sentences","denotations":[{"id":"T41","span":{"begin":187,"end":208},"obj":"Sentence"},{"id":"T42","span":{"begin":210,"end":225},"obj":"Sentence"},{"id":"T43","span":{"begin":226,"end":446},"obj":"Sentence"},{"id":"T44","span":{"begin":447,"end":556},"obj":"Sentence"},{"id":"T45","span":{"begin":557,"end":665},"obj":"Sentence"},{"id":"T46","span":{"begin":666,"end":836},"obj":"Sentence"},{"id":"T47","span":{"begin":838,"end":860},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":" targets CoV, in this article, we have reviewed the possible protein structures, which could be potential targets for the development of a therapeutic approach for the treatment of CoV.\n\nMaterials and Methods\n\nDatabase screen\nWe screened PubMed and RCSB database with the keywords HCoV, NCoV, corona virus, SERS-CoV, MERS-CoV, 2019-nCoV, crystal structure, X-ray crystallography structure, NMR structure, target, and drug target till Feb 3, 2020. The database files were extracted using endnote, and title and abstract screening was done using Rayyan QCRI. Full texts of these screened articles were further screened for possible inclusion in the systematic review. Articles that evaluated different druggable targets of CoV and evaluated different therapeutic measures against some identifiable target were included for further review.\n\nResults and Discussion\nA total of 392 articles were fo"}