PMC:7074424 / 24894-25250 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7074424","sourcedb":"PMC","sourceid":"7074424","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7074424","text":"2AMQ).[82] Lopinavir and ritonavir, which are the inhibitors of HIV protease, also inhibit Mpro.[83] In silico studies directed that among commercially available drugs, colistin, valrubicin, icatibant, bepotastine, epirubicin, epoprostenol, vapreotide, aprepitant, caspofungin, and perphenazine also bind to the lopinavir/ritonavir-binding site on CoV.[83]","tracks":[{"project":"LitCovid-PubTator","denotations":[{"id":"555","span":{"begin":348,"end":351},"obj":"Species"},{"id":"570","span":{"begin":11,"end":20},"obj":"Chemical"},{"id":"571","span":{"begin":179,"end":189},"obj":"Chemical"},{"id":"572","span":{"begin":202,"end":213},"obj":"Chemical"},{"id":"573","span":{"begin":215,"end":225},"obj":"Chemical"},{"id":"574","span":{"begin":227,"end":239},"obj":"Chemical"},{"id":"575","span":{"begin":265,"end":276},"obj":"Chemical"},{"id":"576","span":{"begin":282,"end":294},"obj":"Chemical"},{"id":"577","span":{"begin":312,"end":331},"obj":"Chemical"}],"attributes":[{"id":"A555","pred":"tao:has_database_id","subj":"555","obj":"Tax:11118"},{"id":"A570","pred":"tao:has_database_id","subj":"570","obj":"MESH:D061466"},{"id":"A571","pred":"tao:has_database_id","subj":"571","obj":"MESH:C016163"},{"id":"A572","pred":"tao:has_database_id","subj":"572","obj":"MESH:C108476"},{"id":"A573","pred":"tao:has_database_id","subj":"573","obj":"MESH:D015251"},{"id":"A574","pred":"tao:has_database_id","subj":"574","obj":"MESH:D011464"},{"id":"A575","pred":"tao:has_database_id","subj":"575","obj":"MESH:D000077336"},{"id":"A576","pred":"tao:has_database_id","subj":"576","obj":"MESH:D010546"},{"id":"A577","pred":"tao:has_database_id","subj":"577","obj":"MESH:C558899"},{"subj":"555","pred":"source","obj":"LitCovid-PubTator"},{"subj":"570","pred":"source","obj":"LitCovid-PubTator"},{"subj":"571","pred":"source","obj":"LitCovid-PubTator"},{"subj":"572","pred":"source","obj":"LitCovid-PubTator"},{"subj":"573","pred":"source","obj":"LitCovid-PubTator"},{"subj":"574","pred":"source","obj":"LitCovid-PubTator"},{"subj":"575","pred":"source","obj":"LitCovid-PubTator"},{"subj":"576","pred":"source","obj":"LitCovid-PubTator"},{"subj":"577","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]},{"project":"2_test","denotations":[{"id":"32201449-16128623-47217130","span":{"begin":7,"end":9},"obj":"16128623"},{"id":"T11845","span":{"begin":7,"end":9},"obj":"16128623"}],"attributes":[{"subj":"32201449-16128623-47217130","pred":"source","obj":"2_test"},{"subj":"T11845","pred":"source","obj":"2_test"}]},{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T743","span":{"begin":11,"end":20},"obj":"DG_23"},{"id":"T742","span":{"begin":25,"end":34},"obj":"DG_30"},{"id":"T741","span":{"begin":50,"end":60},"obj":"CHEBI:35222;CHEBI:35222"},{"id":"T740","span":{"begin":162,"end":167},"obj":"CHEBI:23888;CHEBI:23888"},{"id":"T739","span":{"begin":169,"end":177},"obj":"CHEBI:37943;CHEBI:37943"},{"id":"T738","span":{"begin":202,"end":213},"obj":"DG_7"},{"id":"T737","span":{"begin":312,"end":321},"obj":"DG_23;NCBITaxon:11646"},{"id":"T736","span":{"begin":322,"end":331},"obj":"DG_30"},{"id":"T735","span":{"begin":332,"end":344},"obj":"SO:0000409"}],"attributes":[{"subj":"T743","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T742","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T741","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T740","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T739","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T738","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T737","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T736","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T735","pred":"source","obj":"LitCovid-PMC-OGER-BB"}]},{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T257","span":{"begin":64,"end":67},"obj":"Body_part"}],"attributes":[{"id":"A257","pred":"fma_id","subj":"T257","obj":"http://purl.org/sig/ont/fma/fma278683"},{"subj":"T257","pred":"source","obj":"LitCovid-PD-FMA-UBERON"}]},{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T302","span":{"begin":11,"end":20},"obj":"Chemical"},{"id":"T303","span":{"begin":25,"end":34},"obj":"Chemical"},{"id":"T304","span":{"begin":50,"end":60},"obj":"Chemical"},{"id":"T305","span":{"begin":162,"end":167},"obj":"Chemical"},{"id":"T306","span":{"begin":169,"end":177},"obj":"Chemical"},{"id":"T307","span":{"begin":179,"end":189},"obj":"Chemical"},{"id":"T308","span":{"begin":191,"end":200},"obj":"Chemical"},{"id":"T309","span":{"begin":202,"end":213},"obj":"Chemical"},{"id":"T310","span":{"begin":215,"end":225},"obj":"Chemical"},{"id":"T311","span":{"begin":253,"end":263},"obj":"Chemical"},{"id":"T312","span":{"begin":265,"end":276},"obj":"Chemical"},{"id":"T313","span":{"begin":282,"end":294},"obj":"Chemical"},{"id":"T314","span":{"begin":312,"end":331},"obj":"Chemical"},{"id":"T315","span":{"begin":312,"end":321},"obj":"Chemical"},{"id":"T316","span":{"begin":322,"end":331},"obj":"Chemical"}],"attributes":[{"id":"A302","pred":"chebi_id","subj":"T302","obj":"http://purl.obolibrary.org/obo/CHEBI_31781"},{"id":"A303","pred":"chebi_id","subj":"T303","obj":"http://purl.obolibrary.org/obo/CHEBI_45409"},{"id":"A304","pred":"chebi_id","subj":"T304","obj":"http://purl.obolibrary.org/obo/CHEBI_35222"},{"id":"A305","pred":"chebi_id","subj":"T305","obj":"http://purl.obolibrary.org/obo/CHEBI_23888"},{"id":"A306","pred":"chebi_id","subj":"T306","obj":"http://purl.obolibrary.org/obo/CHEBI_37943"},{"id":"A307","pred":"chebi_id","subj":"T307","obj":"http://purl.obolibrary.org/obo/CHEBI_135876"},{"id":"A308","pred":"chebi_id","subj":"T308","obj":"http://purl.obolibrary.org/obo/CHEBI_68556"},{"id":"A309","pred":"chebi_id","subj":"T309","obj":"http://purl.obolibrary.org/obo/CHEBI_71204"},{"id":"A310","pred":"chebi_id","subj":"T310","obj":"http://purl.obolibrary.org/obo/CHEBI_47898"},{"id":"A311","pred":"chebi_id","subj":"T311","obj":"http://purl.obolibrary.org/obo/CHEBI_499361"},{"id":"A312","pred":"chebi_id","subj":"T312","obj":"http://purl.obolibrary.org/obo/CHEBI_474180"},{"id":"A313","pred":"chebi_id","subj":"T313","obj":"http://purl.obolibrary.org/obo/CHEBI_8028"},{"id":"A314","pred":"chebi_id","subj":"T314","obj":"http://purl.obolibrary.org/obo/CHEBI_145924"},{"id":"A315","pred":"chebi_id","subj":"T315","obj":"http://purl.obolibrary.org/obo/CHEBI_31781"},{"id":"A316","pred":"chebi_id","subj":"T316","obj":"http://purl.obolibrary.org/obo/CHEBI_45409"},{"subj":"T302","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T303","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T304","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T305","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T306","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T307","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T308","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T309","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T310","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T311","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T312","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T313","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T314","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T315","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T316","pred":"source","obj":"LitCovid-PD-CHEBI"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T147","span":{"begin":0,"end":356},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T147","pred":"source","obj":"LitCovid-sentences"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PubTator","color":"#ec93e0","default":true},{"id":"2_test","color":"#93ecde"},{"id":"LitCovid-PMC-OGER-BB","color":"#ecc493"},{"id":"LitCovid-PD-FMA-UBERON","color":"#aa93ec"},{"id":"LitCovid-PD-CHEBI","color":"#95ec93"},{"id":"LitCovid-sentences","color":"#ec93af"}]}]}}