PMC:7074424 / 23262-23650 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"521","span":{"begin":28,"end":31},"obj":"Chemical"},{"id":"522","span":{"begin":270,"end":273},"obj":"Chemical"},{"id":"523","span":{"begin":329,"end":334},"obj":"Chemical"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"The C-terminal end of these PPs is cleaved by chymotrypsin-like cysteine protease (main protease [Mpro] or 3C-like protease [3CLpro]) and the N-terminal end is processed by the Mpro (also known as papain-like protease [PLpro]).[74] The first three cleavage sites of the PPs is cut by PLpro while the rest 11 sites are cleaved by CLpro, and this cleavage results in release of 16 NSPs.[75]"}

{"project":"2_test","denotations":[{"id":"32201449-16306591-47217116","span":{"begin":228,"end":230},"obj":"16306591"},{"id":"32201449-31724441-47217117","span":{"begin":385,"end":387},"obj":"31724441"},{"id":"T90942","span":{"begin":228,"end":230},"obj":"16306591"},{"id":"T76544","span":{"begin":385,"end":387},"obj":"31724441"}],"text":"The C-terminal end of these PPs is cleaved by chymotrypsin-like cysteine protease (main protease [Mpro] or 3C-like protease [3CLpro]) and the N-terminal end is processed by the Mpro (also known as papain-like protease [PLpro]).[74] The first three cleavage sites of the PPs is cut by PLpro while the rest 11 sites are cleaved by CLpro, and this cleavage results in release of 16 NSPs.[75]"}

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T784","span":{"begin":35,"end":42},"obj":"MOP:0000780"},{"id":"T783","span":{"begin":248,"end":256},"obj":"MOP:0000780"},{"id":"T782","span":{"begin":277,"end":280},"obj":"MOP:0000780"},{"id":"T781","span":{"begin":318,"end":325},"obj":"MOP:0000780"},{"id":"T780","span":{"begin":345,"end":353},"obj":"MOP:0000780"}],"text":"The C-terminal end of these PPs is cleaved by chymotrypsin-like cysteine protease (main protease [Mpro] or 3C-like protease [3CLpro]) and the N-terminal end is processed by the Mpro (also known as papain-like protease [PLpro]).[74] The first three cleavage sites of the PPs is cut by PLpro while the rest 11 sites are cleaved by CLpro, and this cleavage results in release of 16 NSPs.[75]"}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T255","span":{"begin":64,"end":72},"obj":"Body_part"}],"attributes":[{"id":"A255","pred":"fma_id","subj":"T255","obj":"http://purl.org/sig/ont/fma/fma82751"}],"text":"The C-terminal end of these PPs is cleaved by chymotrypsin-like cysteine protease (main protease [Mpro] or 3C-like protease [3CLpro]) and the N-terminal end is processed by the Mpro (also known as papain-like protease [PLpro]).[74] The first three cleavage sites of the PPs is cut by PLpro while the rest 11 sites are cleaved by CLpro, and this cleavage results in release of 16 NSPs.[75]"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T250","span":{"begin":305,"end":307},"obj":"http://purl.obolibrary.org/obo/CLO_0053733"}],"text":"The C-terminal end of these PPs is cleaved by chymotrypsin-like cysteine protease (main protease [Mpro] or 3C-like protease [3CLpro]) and the N-terminal end is processed by the Mpro (also known as papain-like protease [PLpro]).[74] The first three cleavage sites of the PPs is cut by PLpro while the rest 11 sites are cleaved by CLpro, and this cleavage results in release of 16 NSPs.[75]"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T278","span":{"begin":64,"end":72},"obj":"Chemical"}],"attributes":[{"id":"A278","pred":"chebi_id","subj":"T278","obj":"http://purl.obolibrary.org/obo/CHEBI_15356"}],"text":"The C-terminal end of these PPs is cleaved by chymotrypsin-like cysteine protease (main protease [Mpro] or 3C-like protease [3CLpro]) and the N-terminal end is processed by the Mpro (also known as papain-like protease [PLpro]).[74] The first three cleavage sites of the PPs is cut by PLpro while the rest 11 sites are cleaved by CLpro, and this cleavage results in release of 16 NSPs.[75]"}

{"project":"LitCovid-sentences","denotations":[{"id":"T137","span":{"begin":0,"end":388},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"The C-terminal end of these PPs is cleaved by chymotrypsin-like cysteine protease (main protease [Mpro] or 3C-like protease [3CLpro]) and the N-terminal end is processed by the Mpro (also known as papain-like protease [PLpro]).[74] The first three cleavage sites of the PPs is cut by PLpro while the rest 11 sites are cleaved by CLpro, and this cleavage results in release of 16 NSPs.[75]"}