PMC:7073332 / 39863-40613
Annnotations
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 1109 | 566-571 | Species | denotes | human | Tax:9606 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T160 | 221-224 | Disease | denotes | BPS | http://purl.obolibrary.org/obo/MONDO_0009901 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T276 | 566-571 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T277 | 598-599 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T445 | 13-17 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T446 | 52-56 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T447 | 154-157 | Chemical | denotes | TTD | http://purl.obolibrary.org/obo/CHEBI_73659 |
| T448 | 281-285 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T449 | 342-346 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T450 | 687-691 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T248 | 0-32 | Sentence | denotes | Building the drug–target network |
| T249 | 33-249 | Sentence | denotes | Here, we collected drug–target interaction information from the DrugBank database (v4.3)86, Therapeutic Target Database (TTD)87, PharmGKB database, ChEMBL (v20)88, BindingDB89, and IUPHAR/BPS Guide to PHARMACOLOGY90. |
| T250 | 250-335 | Sentence | denotes | The chemical structure of each drug with SMILES format was extracted from DrugBank86. |
| T251 | 336-632 | Sentence | denotes | Here, drug–target interactions meeting the following three criteria were used: (i) binding affinities, including Ki, Kd, IC50, or EC50 each ≤10 μM; (ii) the target was marked as “reviewed” in the UniProt database91; and (iii) the human target was represented by a unique UniProt accession number. |
| T252 | 633-750 | Sentence | denotes | The details for building the experimentally validated drug–target network are provided in our recent studies13,23,28. |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32194980-24203711-19614251 | 121-123 | 24203711 | denotes | 86 |
| 32194980-26578601-19614252 | 158-160 | 26578601 | denotes | 87 |
| 32194980-21948594-19614253 | 193-195 | 21948594 | denotes | 88 |
| 32194980-17145705-19614254 | 206-208 | 17145705 | denotes | 89 |
| 32194980-24234439-19614255 | 246-248 | 24234439 | denotes | 90 |
| 32194980-24203711-19614256 | 332-334 | 24203711 | denotes | 86 |
| 32194980-14681372-19614257 | 548-550 | 14681372 | denotes | 91 |
| 32194980-30002366-19614258 | 741-743 | 30002366 | denotes | 13 |
| 32194980-31375661-19614259 | 744-746 | 31375661 | denotes | 23 |
| 32194980-30867426-19614260 | 747-749 | 30867426 | denotes | 28 |