> top > docs > PMC:7073332 > spans > 30354-31205 > annotations

PMC:7073332 / 30354-31205 JSONTXT

Annnotations TAB JSON ListView MergeView

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
874 0-10 Chemical denotes Toremifene MESH:D017312
875 16-22 Chemical denotes Emodin MESH:D004642
896 651-655 Gene denotes ACE2 Gene:59272
897 633-638 Gene denotes spike Gene:43740568
898 246-257 Species denotes Ebola virus Tax:1570291
899 344-352 Species denotes MERS-CoV Tax:1335626
900 367-370 Species denotes CoV Tax:11118
901 448-464 Species denotes rheum tanguticum Tax:137226
902 551-559 Species denotes SARS-CoV Tax:694009
903 624-632 Species denotes SARS-CoV Tax:694009
904 820-829 Species denotes 2019-nCoV Tax:2697049
905 830-840 Species denotes SARS-CoV-2 Tax:2697049
906 23-33 Chemical denotes Toremifene MESH:D017312
907 158-168 Chemical denotes toremifene MESH:D017312
908 313-323 Chemical denotes toremifene MESH:D017312
909 384-390 Chemical denotes Emodin MESH:D004642
910 395-408 Chemical denotes anthraquinone MESH:D000880
911 534-540 Chemical denotes emdoin
912 753-763 Chemical denotes toremifene MESH:D017312
913 768-774 Chemical denotes emdoin
914 124-137 Disease denotes breast cancer MESH:D001943
915 186-201 Disease denotes virus infection MESH:D001102

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T152 124-130 Body_part denotes breast http://purl.org/sig/ont/fma/fma9601
T153 639-646 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T8 124-130 Body_part denotes breast http://purl.obolibrary.org/obo/UBERON_0000310

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T127 180-185 Disease denotes Ebola http://purl.obolibrary.org/obo/MONDO_0005737
T128 246-251 Disease denotes Ebola http://purl.obolibrary.org/obo/MONDO_0005737
T129 551-559 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T130 624-632 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T131 830-838 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T223 124-130 http://purl.obolibrary.org/obo/UBERON_0000310 denotes breast
T224 186-191 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T225 252-257 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T226 466-469 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T227 505-510 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T228 662-664 http://purl.obolibrary.org/obo/CLO_0054055 denotes 71
T229 783-784 http://purl.obolibrary.org/obo/CLO_0001020 denotes a

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T354 16-22 Chemical denotes Emodin http://purl.obolibrary.org/obo/CHEBI_42223
T355 158-168 Chemical denotes toremifene http://purl.obolibrary.org/obo/CHEBI_9635
T356 313-323 Chemical denotes toremifene http://purl.obolibrary.org/obo/CHEBI_9635
T357 384-390 Chemical denotes Emodin http://purl.obolibrary.org/obo/CHEBI_42223
T358 395-408 Chemical denotes anthraquinone http://purl.obolibrary.org/obo/CHEBI_22580|http://purl.obolibrary.org/obo/CHEBI_40448
T360 639-646 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T361 753-763 Chemical denotes toremifene http://purl.obolibrary.org/obo/CHEBI_9635

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T51 334-340 http://purl.obolibrary.org/obo/GO_0040007 denotes growth

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T184 0-22 Sentence denotes Toremifene plus Emodin
T185 23-140 Sentence denotes Toremifene is among the approved first-generation nonsteroidal SERMs for the treatment of metastatic breast cancer68.
T186 141-273 Sentence denotes SERMs (including toremifene) inhibited Ebola virus infection18 by interacting with and destabilizing the Ebola virus glycoprotein39.
T187 274-383 Sentence denotes In vitro assays have demonstrated that toremifene inhibited growth of MERS-CoV17,69 and SARA-CoV38 (Table 1).
T188 384-519 Sentence denotes Emodin, an anthraquinone derivative extracted from the roots of rheum tanguticum, has been reported to have various anti-virus effects.
T189 520-661 Sentence denotes Specifically, emdoin inhibited SARS-CoV-associated 3a protein70, and blocked an interaction between the SARS-CoV spike protein and ACE2 (ref.
T190 662-666 Sentence denotes 71).
T191 667-851 Sentence denotes Altogether, network analyses and published experimental data suggested that combining toremifene and emdoin offered a potential therapeutic approach for 2019-nCoV/SARS-CoV-2 (Fig. 6c).

2_test

Id Subject Object Predicate Lexical cue
32194980-21553116-19614221 137-139 21553116 denotes 68
32194980-27362232-19614222 270-272 27362232 denotes 39
32194980-24841273-19614223 352-354 24841273 denotes 17
32194980-29566060-19614224 355-357 29566060 denotes 69
32194980-24841269-19614225 370-372 24841269 denotes 38
32194980-21356245-19614226 581-583 21356245 denotes 70
32194980-16730806-19614227 662-664 16730806 denotes 71