PMC:7073332 / 27484-27777 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"826","span":{"begin":42,"end":54},"obj":"Disease"},{"id":"827","span":{"begin":59,"end":65},"obj":"Disease"}],"attributes":[{"id":"A826","pred":"tao:has_database_id","subj":"826","obj":"MESH:D006973"},{"id":"A827","pred":"tao:has_database_id","subj":"827","obj":"MESH:D009369"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Relying on approved drug combinations for hypertension and cancer, we found that a drug combination was therapeutically effective only if it was captured by the “Complementary Exposure” pattern: the targets of the drugs both hit the disease module, but target separate neighborhoods (Fig. 6a)."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T117","span":{"begin":42,"end":54},"obj":"Disease"},{"id":"T118","span":{"begin":59,"end":65},"obj":"Disease"}],"attributes":[{"id":"A117","pred":"mondo_id","subj":"T117","obj":"http://purl.obolibrary.org/obo/MONDO_0005044"},{"id":"A118","pred":"mondo_id","subj":"T118","obj":"http://purl.obolibrary.org/obo/MONDO_0004992"}],"text":"Relying on approved drug combinations for hypertension and cancer, we found that a drug combination was therapeutically effective only if it was captured by the “Complementary Exposure” pattern: the targets of the drugs both hit the disease module, but target separate neighborhoods (Fig. 6a)."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T203","span":{"begin":81,"end":82},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"Relying on approved drug combinations for hypertension and cancer, we found that a drug combination was therapeutically effective only if it was captured by the “Complementary Exposure” pattern: the targets of the drugs both hit the disease module, but target separate neighborhoods (Fig. 6a)."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T307","span":{"begin":20,"end":24},"obj":"Chemical"},{"id":"T308","span":{"begin":83,"end":87},"obj":"Chemical"},{"id":"T309","span":{"begin":214,"end":219},"obj":"Chemical"}],"attributes":[{"id":"A307","pred":"chebi_id","subj":"T307","obj":"http://purl.obolibrary.org/obo/CHEBI_23888"},{"id":"A308","pred":"chebi_id","subj":"T308","obj":"http://purl.obolibrary.org/obo/CHEBI_23888"},{"id":"A309","pred":"chebi_id","subj":"T309","obj":"http://purl.obolibrary.org/obo/CHEBI_23888"}],"text":"Relying on approved drug combinations for hypertension and cancer, we found that a drug combination was therapeutically effective only if it was captured by the “Complementary Exposure” pattern: the targets of the drugs both hit the disease module, but target separate neighborhoods (Fig. 6a)."}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T19","span":{"begin":42,"end":54},"obj":"Phenotype"},{"id":"T20","span":{"begin":59,"end":65},"obj":"Phenotype"}],"attributes":[{"id":"A19","pred":"hp_id","subj":"T19","obj":"http://purl.obolibrary.org/obo/HP_0000822"},{"id":"A20","pred":"hp_id","subj":"T20","obj":"http://purl.obolibrary.org/obo/HP_0002664"}],"text":"Relying on approved drug combinations for hypertension and cancer, we found that a drug combination was therapeutically effective only if it was captured by the “Complementary Exposure” pattern: the targets of the drugs both hit the disease module, but target separate neighborhoods (Fig. 6a)."}

{"project":"LitCovid-sentences","denotations":[{"id":"T168","span":{"begin":0,"end":293},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Relying on approved drug combinations for hypertension and cancer, we found that a drug combination was therapeutically effective only if it was captured by the “Complementary Exposure” pattern: the targets of the drugs both hit the disease module, but target separate neighborhoods (Fig. 6a)."}