PMC:7073332 / 11620-12240 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"328","span":{"begin":386,"end":391},"obj":"Gene"},{"id":"329","span":{"begin":528,"end":533},"obj":"Gene"},{"id":"330","span":{"begin":55,"end":64},"obj":"Species"},{"id":"331","span":{"begin":65,"end":75},"obj":"Species"},{"id":"332","span":{"begin":115,"end":123},"obj":"Species"},{"id":"333","span":{"begin":206,"end":215},"obj":"Species"},{"id":"334","span":{"begin":216,"end":226},"obj":"Species"},{"id":"335","span":{"begin":338,"end":346},"obj":"Species"},{"id":"336","span":{"begin":478,"end":487},"obj":"Species"},{"id":"337","span":{"begin":488,"end":498},"obj":"Species"},{"id":"338","span":{"begin":503,"end":511},"obj":"Species"},{"id":"339","span":{"begin":545,"end":554},"obj":"Species"},{"id":"340","span":{"begin":555,"end":565},"obj":"Species"},{"id":"341","span":{"begin":611,"end":619},"obj":"Species"}],"attributes":[{"id":"A328","pred":"tao:has_database_id","subj":"328","obj":"Gene:43740568"},{"id":"A329","pred":"tao:has_database_id","subj":"329","obj":"Gene:43740568"},{"id":"A330","pred":"tao:has_database_id","subj":"330","obj":"Tax:2697049"},{"id":"A331","pred":"tao:has_database_id","subj":"331","obj":"Tax:2697049"},{"id":"A332","pred":"tao:has_database_id","subj":"332","obj":"Tax:694009"},{"id":"A333","pred":"tao:has_database_id","subj":"333","obj":"Tax:2697049"},{"id":"A334","pred":"tao:has_database_id","subj":"334","obj":"Tax:2697049"},{"id":"A335","pred":"tao:has_database_id","subj":"335","obj":"Tax:694009"},{"id":"A336","pred":"tao:has_database_id","subj":"336","obj":"Tax:2697049"},{"id":"A337","pred":"tao:has_database_id","subj":"337","obj":"Tax:2697049"},{"id":"A338","pred":"tao:has_database_id","subj":"338","obj":"Tax:694009"},{"id":"A339","pred":"tao:has_database_id","subj":"339","obj":"Tax:2697049"},{"id":"A340","pred":"tao:has_database_id","subj":"340","obj":"Tax:2697049"},{"id":"A341","pred":"tao:has_database_id","subj":"341","obj":"Tax:1335626"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Protein sequence alignment analyses indicated that the 2019-nCoV/SARS-CoV-2 was most evolutionarily conserved with SARS-CoV (Supplementary Table S2). Specifically, the envelope and nucleocapsid proteins of 2019-nCoV/SARS-CoV-2 are two evolutionarily conserved regions, with sequence identities of 96% and 89.6%, respectively, compared to SARS-CoV (Supplementary Table S2). However, the spike protein exhibited the lowest sequence conservation (sequence identity of 77%) between 2019-nCoV/SARS-CoV-2 and SARS-CoV. Meanwhile, the spike protein of 2019-nCoV/SARS-CoV-2 only has 31.9% sequence identity compared to MERS-CoV."}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T50","span":{"begin":0,"end":7},"obj":"Body_part"},{"id":"T51","span":{"begin":194,"end":202},"obj":"Body_part"},{"id":"T52","span":{"begin":392,"end":399},"obj":"Body_part"},{"id":"T53","span":{"begin":534,"end":541},"obj":"Body_part"}],"attributes":[{"id":"A50","pred":"fma_id","subj":"T50","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A51","pred":"fma_id","subj":"T51","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A52","pred":"fma_id","subj":"T52","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A53","pred":"fma_id","subj":"T53","obj":"http://purl.org/sig/ont/fma/fma67257"}],"text":"Protein sequence alignment analyses indicated that the 2019-nCoV/SARS-CoV-2 was most evolutionarily conserved with SARS-CoV (Supplementary Table S2). Specifically, the envelope and nucleocapsid proteins of 2019-nCoV/SARS-CoV-2 are two evolutionarily conserved regions, with sequence identities of 96% and 89.6%, respectively, compared to SARS-CoV (Supplementary Table S2). However, the spike protein exhibited the lowest sequence conservation (sequence identity of 77%) between 2019-nCoV/SARS-CoV-2 and SARS-CoV. Meanwhile, the spike protein of 2019-nCoV/SARS-CoV-2 only has 31.9% sequence identity compared to MERS-CoV."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T47","span":{"begin":65,"end":73},"obj":"Disease"},{"id":"T48","span":{"begin":115,"end":123},"obj":"Disease"},{"id":"T49","span":{"begin":216,"end":224},"obj":"Disease"},{"id":"T50","span":{"begin":338,"end":346},"obj":"Disease"},{"id":"T51","span":{"begin":488,"end":496},"obj":"Disease"},{"id":"T52","span":{"begin":503,"end":511},"obj":"Disease"},{"id":"T53","span":{"begin":555,"end":563},"obj":"Disease"}],"attributes":[{"id":"A47","pred":"mondo_id","subj":"T47","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A48","pred":"mondo_id","subj":"T48","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A49","pred":"mondo_id","subj":"T49","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A50","pred":"mondo_id","subj":"T50","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A51","pred":"mondo_id","subj":"T51","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A52","pred":"mondo_id","subj":"T52","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A53","pred":"mondo_id","subj":"T53","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"Protein sequence alignment analyses indicated that the 2019-nCoV/SARS-CoV-2 was most evolutionarily conserved with SARS-CoV (Supplementary Table S2). Specifically, the envelope and nucleocapsid proteins of 2019-nCoV/SARS-CoV-2 are two evolutionarily conserved regions, with sequence identities of 96% and 89.6%, respectively, compared to SARS-CoV (Supplementary Table S2). However, the spike protein exhibited the lowest sequence conservation (sequence identity of 77%) between 2019-nCoV/SARS-CoV-2 and SARS-CoV. Meanwhile, the spike protein of 2019-nCoV/SARS-CoV-2 only has 31.9% sequence identity compared to MERS-CoV."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T79","span":{"begin":145,"end":147},"obj":"http://purl.obolibrary.org/obo/CLO_0008922"},{"id":"T80","span":{"begin":145,"end":147},"obj":"http://purl.obolibrary.org/obo/CLO_0050052"},{"id":"T81","span":{"begin":368,"end":370},"obj":"http://purl.obolibrary.org/obo/CLO_0008922"},{"id":"T82","span":{"begin":368,"end":370},"obj":"http://purl.obolibrary.org/obo/CLO_0050052"},{"id":"T83","span":{"begin":571,"end":574},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"}],"text":"Protein sequence alignment analyses indicated that the 2019-nCoV/SARS-CoV-2 was most evolutionarily conserved with SARS-CoV (Supplementary Table S2). Specifically, the envelope and nucleocapsid proteins of 2019-nCoV/SARS-CoV-2 are two evolutionarily conserved regions, with sequence identities of 96% and 89.6%, respectively, compared to SARS-CoV (Supplementary Table S2). However, the spike protein exhibited the lowest sequence conservation (sequence identity of 77%) between 2019-nCoV/SARS-CoV-2 and SARS-CoV. Meanwhile, the spike protein of 2019-nCoV/SARS-CoV-2 only has 31.9% sequence identity compared to MERS-CoV."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T107","span":{"begin":0,"end":7},"obj":"Chemical"},{"id":"T108","span":{"begin":145,"end":147},"obj":"Chemical"},{"id":"T109","span":{"begin":194,"end":202},"obj":"Chemical"},{"id":"T110","span":{"begin":368,"end":370},"obj":"Chemical"},{"id":"T111","span":{"begin":392,"end":399},"obj":"Chemical"},{"id":"T112","span":{"begin":534,"end":541},"obj":"Chemical"}],"attributes":[{"id":"A107","pred":"chebi_id","subj":"T107","obj":"http://purl.obolibrary.org/obo/CHEBI_16541"},{"id":"A108","pred":"chebi_id","subj":"T108","obj":"http://purl.obolibrary.org/obo/CHEBI_29387"},{"id":"A109","pred":"chebi_id","subj":"T109","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A110","pred":"chebi_id","subj":"T110","obj":"http://purl.obolibrary.org/obo/CHEBI_29387"},{"id":"A111","pred":"chebi_id","subj":"T111","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A112","pred":"chebi_id","subj":"T112","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"}],"text":"Protein sequence alignment analyses indicated that the 2019-nCoV/SARS-CoV-2 was most evolutionarily conserved with SARS-CoV (Supplementary Table S2). Specifically, the envelope and nucleocapsid proteins of 2019-nCoV/SARS-CoV-2 are two evolutionarily conserved regions, with sequence identities of 96% and 89.6%, respectively, compared to SARS-CoV (Supplementary Table S2). However, the spike protein exhibited the lowest sequence conservation (sequence identity of 77%) between 2019-nCoV/SARS-CoV-2 and SARS-CoV. Meanwhile, the spike protein of 2019-nCoV/SARS-CoV-2 only has 31.9% sequence identity compared to MERS-CoV."}

{"project":"LitCovid-sentences","denotations":[{"id":"T70","span":{"begin":0,"end":149},"obj":"Sentence"},{"id":"T71","span":{"begin":150,"end":372},"obj":"Sentence"},{"id":"T72","span":{"begin":373,"end":512},"obj":"Sentence"},{"id":"T73","span":{"begin":513,"end":620},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Protein sequence alignment analyses indicated that the 2019-nCoV/SARS-CoV-2 was most evolutionarily conserved with SARS-CoV (Supplementary Table S2). Specifically, the envelope and nucleocapsid proteins of 2019-nCoV/SARS-CoV-2 are two evolutionarily conserved regions, with sequence identities of 96% and 89.6%, respectively, compared to SARS-CoV (Supplementary Table S2). However, the spike protein exhibited the lowest sequence conservation (sequence identity of 77%) between 2019-nCoV/SARS-CoV-2 and SARS-CoV. Meanwhile, the spike protein of 2019-nCoV/SARS-CoV-2 only has 31.9% sequence identity compared to MERS-CoV."}