PMC:7068984 / 25270-27272
Annnotations
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
869 | 691-702 | Gene | denotes | cathepsin B | Gene:1508 |
870 | 965-978 | Gene | denotes | Neuraminidase | Gene:4758 |
871 | 1026-1039 | Gene | denotes | neuraminidase | Gene:4758 |
872 | 131-136 | Species | denotes | HIV-1 | Tax:11676 |
873 | 515-520 | Species | denotes | Ebola | Tax:1570291 |
874 | 746-751 | Species | denotes | Ebola | Tax:1570291 |
875 | 907-918 | Species | denotes | DNA viruses | Tax:2080735 |
876 | 1122-1139 | Species | denotes | Influenza viruses | Tax:11308 |
877 | 1366-1377 | Species | denotes | Herpesvirus | Tax:39059 |
878 | 1659-1664 | Species | denotes | Ebola | Tax:1570291 |
879 | 1678-1682 | Species | denotes | H1N1 | Tax:114727 |
880 | 1966-1971 | Species | denotes | human | Tax:9606 |
881 | 1979-1992 | Species | denotes | coronaviruses | Tax:11118 |
882 | 729-738 | Species | denotes | Influenza | Tax:11309 |
883 | 1666-1675 | Species | denotes | influenza | Tax:11309 |
884 | 222-225 | Species | denotes | HIV | Tax:12721 |
885 | 80-99 | Chemical | denotes | Lopinavir/Ritonavir | MESH:C558899 |
886 | 291-302 | Chemical | denotes | Chloroquine | MESH:D002738 |
887 | 304-318 | Chemical | denotes | -aminoquinolin | |
888 | 432-442 | Chemical | denotes | Remdesivir | MESH:C000606551 |
889 | 613-619 | Chemical | denotes | serine | MESH:D012694 |
890 | 226-230 | Disease | denotes | AIDS | MESH:D000163 |
891 | 383-390 | Disease | denotes | Malaria | MESH:D008288 |
892 | 392-410 | Disease | denotes | autoimmune disease | MESH:D001327 |
893 | 1395-1453 | Disease | denotes | cytomegalovirus AIDS-associated cytomegalovirus infections | MESH:D003586 |
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T168 | 131-134 | Body_part | denotes | HIV | http://purl.org/sig/ont/fma/fma278683 |
T169 | 150-157 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T170 | 222-225 | Body_part | denotes | HIV | http://purl.org/sig/ont/fma/fma278683 |
T171 | 330-339 | Body_part | denotes | endosomal | http://purl.org/sig/ont/fma/fma67180 |
T172 | 453-463 | Body_part | denotes | Nucleotide | http://purl.org/sig/ont/fma/fma82740 |
T173 | 550-553 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
T174 | 613-619 | Body_part | denotes | serine | http://purl.org/sig/ont/fma/fma82764 |
T175 | 851-855 | Body_part | denotes | mRNA | http://purl.org/sig/ont/fma/fma67122 |
T176 | 899-902 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
T177 | 907-910 | Body_part | denotes | DNA | http://purl.org/sig/ont/fma/fma74412 |
T178 | 1081-1085 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T179 | 1221-1228 | Body_part | denotes | guanine | http://purl.org/sig/ont/fma/fma82775 |
T180 | 1520-1523 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
T181 | 1638-1641 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
T182 | 1645-1648 | Body_part | denotes | DNA | http://purl.org/sig/ont/fma/fma74412 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T179 | 185-195 | Disease | denotes | infectious | http://purl.obolibrary.org/obo/MONDO_0005550 |
T180 | 226-230 | Disease | denotes | AIDS | http://purl.obolibrary.org/obo/MONDO_0012268 |
T181 | 232-236 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T182 | 383-390 | Disease | denotes | Malaria | http://purl.obolibrary.org/obo/MONDO_0005136 |
T183 | 392-410 | Disease | denotes | autoimmune disease | http://purl.obolibrary.org/obo/MONDO_0007179 |
T184 | 444-446 | Disease | denotes | GS | http://purl.obolibrary.org/obo/MONDO_0005773 |
T185 | 515-520 | Disease | denotes | Ebola | http://purl.obolibrary.org/obo/MONDO_0005737 |
T186 | 522-526 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T187 | 729-738 | Disease | denotes | Influenza | http://purl.obolibrary.org/obo/MONDO_0005812 |
T188 | 746-751 | Disease | denotes | Ebola | http://purl.obolibrary.org/obo/MONDO_0005737 |
T189 | 925-929 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T190 | 1122-1131 | Disease | denotes | Influenza | http://purl.obolibrary.org/obo/MONDO_0005812 |
T191 | 1411-1415 | Disease | denotes | AIDS | http://purl.obolibrary.org/obo/MONDO_0012268 |
T192 | 1427-1453 | Disease | denotes | cytomegalovirus infections | http://purl.obolibrary.org/obo/MONDO_0005132 |
T193 | 1659-1664 | Disease | denotes | Ebola | http://purl.obolibrary.org/obo/MONDO_0005737 |
T194 | 1666-1683 | Disease | denotes | influenza A(H1N1) | http://purl.obolibrary.org/obo/MONDO_0005460 |
T195 | 1666-1675 | Disease | denotes | influenza | http://purl.obolibrary.org/obo/MONDO_0005812 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T240 | 498-503 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
T241 | 534-535 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T242 | 554-561 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
T243 | 648-656 | http://purl.obolibrary.org/obo/UBERON_0000158 | denotes | membrane |
T244 | 701-702 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | B |
T245 | 718-728 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activities |
T246 | 857-858 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T247 | 874-882 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
T248 | 911-918 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
T249 | 940-942 | http://purl.obolibrary.org/obo/CLO_0001527 | denotes | 94 |
T250 | 1004-1012 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
T251 | 1081-1085 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
T252 | 1132-1139 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
T253 | 1140-1145 | http://purl.obolibrary.org/obo/CLO_0001625 | denotes | A [95 |
T254 | 1201-1202 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T255 | 1676-1677 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T256 | 1820-1821 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T257 | 1914-1922 | http://purl.obolibrary.org/obo/NCBITaxon_2 | denotes | bacteria |
T258 | 1924-1931 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
T259 | 1932-1933 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T260 | 1948-1955 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
T261 | 1966-1971 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
T262 | 1972-1978 | http://purl.obolibrary.org/obo/NCBITaxon_33208 | denotes | animal |
T263 | 1994-1997 | http://purl.obolibrary.org/obo/CLO_0054060 | denotes | 102 |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T178 | 13-19 | Chemical | denotes | Action | http://purl.obolibrary.org/obo/CHEBI_5133 |
T179 | 80-89 | Chemical | denotes | Lopinavir | http://purl.obolibrary.org/obo/CHEBI_31781 |
T180 | 109-119 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
T181 | 150-157 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T182 | 291-302 | Chemical | denotes | Chloroquine | http://purl.obolibrary.org/obo/CHEBI_3638 |
T183 | 362-382 | Chemical | denotes | autophagy inhibitors | http://purl.obolibrary.org/obo/CHEBI_88230 |
T184 | 372-382 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
T185 | 444-451 | Chemical | denotes | GS-5734 | http://purl.obolibrary.org/obo/CHEBI_145994 |
T186 | 444-446 | Chemical | denotes | GS | http://purl.obolibrary.org/obo/CHEBI_73516 |
T187 | 453-463 | Chemical | denotes | Nucleotide | http://purl.obolibrary.org/obo/CHEBI_36976 |
T188 | 473-480 | Chemical | denotes | prodrug | http://purl.obolibrary.org/obo/CHEBI_50266 |
T189 | 613-638 | Chemical | denotes | serine protease inhibitor | http://purl.obolibrary.org/obo/CHEBI_64926 |
T190 | 613-619 | Chemical | denotes | serine | http://purl.obolibrary.org/obo/CHEBI_17822 |
T191 | 620-638 | Chemical | denotes | protease inhibitor | http://purl.obolibrary.org/obo/CHEBI_37670|http://purl.obolibrary.org/obo/CHEBI_60258 |
T193 | 629-638 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
T194 | 704-717 | Chemical | denotes | anticoagulant | http://purl.obolibrary.org/obo/CHEBI_50249 |
T195 | 790-799 | Chemical | denotes | guanosine | http://purl.obolibrary.org/obo/CHEBI_16750 |
T196 | 800-810 | Chemical | denotes | nucleoside | http://purl.obolibrary.org/obo/CHEBI_33838 |
T197 | 907-910 | Chemical | denotes | DNA | http://purl.obolibrary.org/obo/CHEBI_16991 |
T198 | 953-964 | Chemical | denotes | Oseltamivir | http://purl.obolibrary.org/obo/CHEBI_7798 |
T199 | 965-988 | Chemical | denotes | Neuraminidase inhibitor | http://purl.obolibrary.org/obo/CHEBI_52425 |
T200 | 979-988 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
T201 | 1183-1193 | Chemical | denotes | Nucleoside | http://purl.obolibrary.org/obo/CHEBI_33838 |
T202 | 1221-1228 | Chemical | denotes | guanine | http://purl.obolibrary.org/obo/CHEBI_16235 |
T203 | 1312-1323 | Chemical | denotes | Ganciclovir | http://purl.obolibrary.org/obo/CHEBI_465284 |
T204 | 1324-1334 | Chemical | denotes | Nucleoside | http://purl.obolibrary.org/obo/CHEBI_33838 |
T205 | 1349-1358 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
T206 | 1488-1493 | Chemical | denotes | T-705 | http://purl.obolibrary.org/obo/CHEBI_134722 |
T207 | 1495-1505 | Chemical | denotes | Nucleoside | http://purl.obolibrary.org/obo/CHEBI_33838 |
T208 | 1520-1544 | Chemical | denotes | RNA polymerase inhibitor | http://purl.obolibrary.org/obo/CHEBI_37416 |
T209 | 1535-1544 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
T210 | 1645-1648 | Chemical | denotes | DNA | http://purl.obolibrary.org/obo/CHEBI_16991 |
LitCovid-PD-GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T44 | 362-371 | http://purl.obolibrary.org/obo/GO_0016236 | denotes | autophagy |
T45 | 362-371 | http://purl.obolibrary.org/obo/GO_0006914 | denotes | autophagy |
T46 | 648-663 | http://purl.obolibrary.org/obo/GO_0061025 | denotes | membrane fusion |
T47 | 704-728 | http://purl.obolibrary.org/obo/GO_0050819 | denotes | anticoagulant activities |
T48 | 832-841 | http://purl.obolibrary.org/obo/GO_0009058 | denotes | synthesis |
T49 | 1059-1066 | http://purl.obolibrary.org/obo/GO_0007114 | denotes | budding |
T50 | 1087-1104 | http://purl.obolibrary.org/obo/GO_0019079 | denotes | viral replication |
T51 | 1087-1104 | http://purl.obolibrary.org/obo/GO_0019058 | denotes | viral replication |
T52 | 1592-1604 | http://purl.obolibrary.org/obo/GO_0000003 | denotes | reproduction |
T53 | 1645-1658 | http://purl.obolibrary.org/obo/GO_0071897 | denotes | DNA synthesis |
T54 | 1649-1658 | http://purl.obolibrary.org/obo/GO_0009058 | denotes | synthesis |
T55 | 1791-1797 | http://purl.obolibrary.org/obo/GO_0040007 | denotes | growth |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T167 | 0-70 | Sentence | denotes | Status Drugs Action mode Anti-infective mechanism Target diseases Ref. |
T168 | 71-250 | Sentence | denotes | Approved Lopinavir/Ritonavir Protease inhibitors Inhibiting HIV-1 protease for protein cleavage, resulting in non-infectious, immature viral particles HIV/AIDS, SARS, MERS [83–85] |
T169 | 251-418 | Sentence | denotes | Approved, Investigational, Vet approved Chloroquine 9-aminoquinolin Increasing endosomal pH, immunomodulating, autophagy inhibitors Malaria, autoimmune disease [79–82] |
T170 | 419-532 | Sentence | denotes | Experimental Remdesivir (GS-5734) Nucleotide analogue prodrug Interfering with virus post-entry Ebola, SARS, MERS |
T171 | 533-575 | Sentence | denotes | (A wide array of RNA viruses) [76, 88, 89] |
T172 | 576-760 | Sentence | denotes | Investigational Nafamostat Synthetic serine protease inhibitor Prevents membrane fusion by reducing the release of cathepsin B; anticoagulant activities Influenza, MERS, Ebola [90, 91] |
T173 | 761-943 | Sentence | denotes | Approved Ribavirin Synthetic guanosine nucleoside Interfering with the synthesis of viral mRNA (a broad-spectrum activity against several RNA and DNA viruses) HCV, SARS, MERS [92–94] |
T174 | 944-1150 | Sentence | denotes | Approved Oseltamivir Neuraminidase inhibitor Inhibiting the activity of the viral neuraminidase enzyme, preventing budding from the host cell, viral replication, and infectivity Influenza viruses A [95, 96] |
T175 | 1151-1285 | Sentence | denotes | Approved Penciclovir/ Acyclovir Nucleoside analog A synthetic acyclic guanine derivative, resulting in chain termination HSV, VZV [97] |
T176 | 1286-1458 | Sentence | denotes | Approved, Investigational Ganciclovir Nucleoside analog Potent inhibitor of the Herpesvirus family including cytomegalovirus AIDS-associated cytomegalovirus infections [98] |
T177 | 1459-1513 | Sentence | denotes | Investigational Favipiravir (T-705) Nucleoside analog: |
T178 | 1514-1692 | Sentence | denotes | Viral RNA polymerase inhibitor Acting on viral genetic copying to prevent its reproduction, without affecting host cellular RNA or DNA synthesis Ebola, influenza A(H1N1) [99–101] |
T179 | 1693-2002 | Sentence | denotes | Approved, Investigational, Vet approved Nitazoxanide Antiprotozoal agent Modulating the survival, growth, and proliferation of a range of extracellular and intracellular protozoa, helminths, anaerobic and microaerophilic bacteria, viruses A wide range of viruses including human/animal coronaviruses [102–104] |
LitCovid-PD-HP
Id | Subject | Object | Predicate | Lexical cue | hp_id |
---|---|---|---|---|---|
T51 | 392-410 | Phenotype | denotes | autoimmune disease | http://purl.obolibrary.org/obo/HP_0002960 |
2_test
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
32169119-12662125-70132253 | 244-246 | 12662125 | denotes | 83 |
32169119-31900204-70132253 | 244-246 | 31900204 | denotes | 83 |
32169119-14985565-70132253 | 244-246 | 14985565 | denotes | 83 |
32169119-14592603-70132254 | 412-414 | 14592603 | denotes | 79 |
32169119-16115318-70132254 | 412-414 | 16115318 | denotes | 79 |
32169119-25727221-70132254 | 412-414 | 25727221 | denotes | 79 |
32169119-32020029-70132254 | 412-414 | 32020029 | denotes | 79 |
32169119-29511076-70132255 | 564-566 | 29511076 | denotes | 76 |
32169119-30987343-70132256 | 568-570 | 30987343 | denotes | 88 |
32169119-31142680-70132257 | 572-574 | 31142680 | denotes | 89 |
32169119-18220789-70132258 | 753-755 | 18220789 | denotes | 90 |
32169119-26346967-70132259 | 757-759 | 26346967 | denotes | 91 |
32169119-30215672-70132260 | 937-939 | 30215672 | denotes | 92 |
32169119-15018130-70132260 | 937-939 | 15018130 | denotes | 92 |
32169119-24811411-70132261 | 1147-1149 | 24811411 | denotes | 96 |
32169119-29896665-70132262 | 1282-1284 | 29896665 | denotes | 97 |
32169119-29678260-70132263 | 1455-1457 | 29678260 | denotes | 98 |
32169119-24084488-70132264 | 1685-1687 | 24084488 | denotes | 99 |
32169119-25108173-70132265 | 1994-1997 | 25108173 | denotes | 102 |
32169119-25451075-70132265 | 1994-1997 | 25451075 | denotes | 102 |
32169119-27095301-70132265 | 1994-1997 | 27095301 | denotes | 102 |