PMC:7068984 / 10760-12161
Annnotations
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 367 | 0-4 | Gene | denotes | ACE2 | Gene:59272 |
| 368 | 340-344 | Gene | denotes | ACE2 | Gene:59272 |
| 369 | 443-447 | Gene | denotes | ACE2 | Gene:59272 |
| 370 | 866-870 | Gene | denotes | pp1a | Gene:5499 |
| 371 | 1177-1179 | Gene | denotes | ER | Gene:2069 |
| 372 | 1223-1235 | Gene | denotes | nucleocapsid | Gene:43740575 |
| 373 | 46-52 | Species | denotes | humans | Tax:9606 |
| 374 | 84-92 | Species | denotes | SARS-CoV | Tax:694009 |
| 375 | 139-144 | Species | denotes | human | Tax:9606 |
| 376 | 148-153 | Species | denotes | human | Tax:9606 |
| 377 | 241-248 | Species | denotes | patient | Tax:9606 |
| 378 | 290-300 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 379 | 349-357 | Species | denotes | SARS-CoV | Tax:694009 |
| 380 | 403-414 | Species | denotes | coronavirus | Tax:11118 |
| 381 | 466-471 | Species | denotes | human | Tax:9606 |
| 382 | 1249-1257 | Gene | denotes | envelope | Gene:43740570 |
| 383 | 232-240 | Disease | denotes | COVID-19 | MESH:C000657245 |
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T52 | 19-42 | Body_part | denotes | lower respiratory tract | http://purl.org/sig/ont/fma/fma45662 |
| T53 | 66-70 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T54 | 372-384 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
| T55 | 472-477 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T56 | 486-498 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
| T57 | 654-667 | Body_part | denotes | cell membrane | http://purl.org/sig/ont/fma/fma63841 |
| T58 | 654-658 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T59 | 773-779 | Body_part | denotes | genome | http://purl.org/sig/ont/fma/fma84116 |
| T60 | 780-783 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
| T61 | 805-814 | Body_part | denotes | cytoplasm | http://purl.org/sig/ont/fma/fma66835 |
| T62 | 833-836 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
| T63 | 915-923 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T64 | 1110-1118 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T65 | 1134-1142 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T66 | 1154-1175 | Body_part | denotes | endoplasmic reticulum | http://purl.org/sig/ont/fma/fma63842 |
| T67 | 1177-1179 | Body_part | denotes | ER | http://purl.org/sig/ont/fma/fma63842 |
| T68 | 1218-1221 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
| T69 | 1236-1244 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T70 | 1258-1271 | Body_part | denotes | glycoproteins | http://purl.org/sig/ont/fma/fma62925 |
| T71 | 1364-1379 | Body_part | denotes | plasma membrane | http://purl.org/sig/ont/fma/fma63841 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T5 | 19-42 | Body_part | denotes | lower respiratory tract | http://purl.obolibrary.org/obo/UBERON_0001558 |
| T6 | 25-42 | Body_part | denotes | respiratory tract | http://purl.obolibrary.org/obo/UBERON_0000065 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T85 | 84-92 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T86 | 232-240 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T87 | 290-298 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T88 | 349-357 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T85 | 19-42 | http://purl.obolibrary.org/obo/UBERON_0001558 | denotes | lower respiratory tract |
| T86 | 46-52 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | humans |
| T87 | 66-70 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T88 | 94-96 | http://purl.obolibrary.org/obo/CLO_0050509 | denotes | 27 |
| T89 | 139-144 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T90 | 148-153 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T91 | 230-231 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T92 | 466-477 | http://purl.obolibrary.org/obo/CLO_0053065 | denotes | human cells |
| T93 | 522-524 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
| T94 | 529-531 | http://purl.obolibrary.org/obo/CLO_0008922 | denotes | S2 |
| T95 | 529-531 | http://purl.obolibrary.org/obo/CLO_0050052 | denotes | S2 |
| T96 | 538-540 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
| T97 | 556-561 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T98 | 636-638 | http://purl.obolibrary.org/obo/CLO_0008922 | denotes | S2 |
| T99 | 636-638 | http://purl.obolibrary.org/obo/CLO_0050052 | denotes | S2 |
| T100 | 648-653 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T101 | 654-658 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T102 | 659-667 | http://purl.obolibrary.org/obo/UBERON_0000158 | denotes | membrane |
| T103 | 746-754 | http://purl.obolibrary.org/obo/UBERON_0000158 | denotes | membrane |
| T104 | 984-992 | http://purl.obolibrary.org/obo/UBERON_0000158 | denotes | membrane |
| T105 | 1002-1004 | http://purl.obolibrary.org/obo/CLO_0001302 | denotes | 34 |
| T106 | 1049-1050 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T107 | 1082-1084 | http://purl.obolibrary.org/obo/CLO_0001000 | denotes | 35 |
| T108 | 1192-1194 | http://purl.obolibrary.org/obo/CLO_0001313 | denotes | 36 |
| T109 | 1364-1370 | http://purl.obolibrary.org/obo/UBERON_0001969 | denotes | plasma |
| T110 | 1371-1379 | http://purl.obolibrary.org/obo/UBERON_0000158 | denotes | membrane |
| T111 | 1395-1400 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T35 | 372-384 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
| T36 | 486-498 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
| T37 | 529-531 | Chemical | denotes | S2 | http://purl.obolibrary.org/obo/CHEBI_29387 |
| T38 | 636-638 | Chemical | denotes | S2 | http://purl.obolibrary.org/obo/CHEBI_29387 |
| T39 | 915-923 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T40 | 1110-1118 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T41 | 1134-1142 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T42 | 1236-1244 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T43 | 1258-1271 | Chemical | denotes | glycoproteins | http://purl.obolibrary.org/obo/CHEBI_17089 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T14 | 586-593 | http://purl.obolibrary.org/obo/GO_0009606 | denotes | tropism |
| T15 | 659-674 | http://purl.obolibrary.org/obo/GO_0061025 | denotes | membrane fusion |
| T16 | 746-761 | http://purl.obolibrary.org/obo/GO_0061025 | denotes | membrane fusion |
| T17 | 946-959 | http://purl.obolibrary.org/obo/GO_0006351 | denotes | transcription |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T77 | 0-172 | Sentence | denotes | ACE2, found in the lower respiratory tract of humans, is known as cell receptor for SARS-CoV [27] and regulates both the cross-species and human-to-human transmission [28]. |
| T78 | 173-358 | Sentence | denotes | Isolated from the bronchoalveolar lavage fluid (BALF) of a COVID-19 patient, Zhou et al. [8] have confirmed that the SARS-CoV-2 uses the same cellular entry receptor, ACE2, as SARS-CoV. |
| T79 | 359-483 | Sentence | denotes | The virion S-glycoprotein on the surface of coronavirus can attach to the receptor, ACE2 on the surface of human cells [29]. |
| T80 | 484-537 | Sentence | denotes | S glycoprotein includes two subunits, S1 and S2 [30]. |
| T81 | 538-739 | Sentence | denotes | S1 determines the virus-host range and cellular tropism with the key function domain − RBD, while S2 mediates virus-cell membrane fusion by two tandem domains, heptad repeats 1 (HR1) [31] and HR2 [32]. |
| T82 | 740-1006 | Sentence | denotes | After membrane fusion, the viral genome RNA is released into the cytoplasm, and the uncoated RNA translates two polyproteins, pp1a and pp1ab [33], which encode non-structural proteins, and form replication-transcription complex (RTC) in double-membrane vesicle [34]. |
| T83 | 1007-1143 | Sentence | denotes | Continuously RTC replicate and synthesize a nested set of subgenomic RNAs [35], which encode accessory proteins and structural proteins. |
| T84 | 1144-1310 | Sentence | denotes | Mediating endoplasmic reticulum (ER) and Golgi [36], newly formed genomic RNA, nucleocapsid proteins and envelope glycoproteins assemble and form viral particle buds. |
| T85 | 1311-1401 | Sentence | denotes | Lastly, the virion-containing vesicles fuse with the plasma membrane to release the virus. |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32169119-16282461-70132203 | 94-96 | 16282461 | denotes | 27 |
| 32169119-32015507-70132204 | 263-264 | 32015507 | denotes | 8 |
| 32169119-31522710-70132205 | 479-481 | 31522710 | denotes | 29 |
| 32169119-24766432-70132206 | 533-535 | 24766432 | denotes | 30 |
| 32169119-28643204-70132207 | 882-884 | 28643204 | denotes | 33 |
| 32169119-15609508-70132208 | 1002-1004 | 15609508 | denotes | 34 |
| 32169119-15827143-70132209 | 1082-1084 | 15827143 | denotes | 35 |
| 32169119-31399512-70132210 | 1192-1194 | 31399512 | denotes | 36 |