PMC:7068163 / 12216-13087
Annnotations
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 168 | 741-742 | Gene | denotes | E | Gene:43740570 |
| 169 | 477-478 | Gene | denotes | E | Gene:43740570 |
| 170 | 26-34 | Species | denotes | SARS-CoV | Tax:694009 |
| 171 | 488-498 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T37 | 37-41 | Body_part | denotes | gene | http://purl.org/sig/ont/fma/fma74402 |
| T38 | 85-89 | Body_part | denotes | gene | http://purl.org/sig/ont/fma/fma74402 |
| T39 | 182-186 | Body_part | denotes | gene | http://purl.org/sig/ont/fma/fma74402 |
| T40 | 479-483 | Body_part | denotes | gene | http://purl.org/sig/ont/fma/fma74402 |
| T41 | 510-514 | Body_part | denotes | gene | http://purl.org/sig/ont/fma/fma74402 |
| T42 | 743-747 | Body_part | denotes | gene | http://purl.org/sig/ont/fma/fma74402 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T44 | 26-34 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T45 | 488-496 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T114 | 37-41 | http://purl.obolibrary.org/obo/OGG_0000000002 | denotes | gene |
| T115 | 85-89 | http://purl.obolibrary.org/obo/OGG_0000000002 | denotes | gene |
| T116 | 182-186 | http://purl.obolibrary.org/obo/OGG_0000000002 | denotes | gene |
| T117 | 233-234 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T118 | 282-285 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T119 | 375-376 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T120 | 479-483 | http://purl.obolibrary.org/obo/OGG_0000000002 | denotes | gene |
| T121 | 510-514 | http://purl.obolibrary.org/obo/OGG_0000000002 | denotes | gene |
| T122 | 541-548 | http://purl.obolibrary.org/obo/SO_0000418 | denotes | signals |
| T123 | 604-611 | http://purl.obolibrary.org/obo/SO_0000418 | denotes | signals |
| T124 | 702-710 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T125 | 743-747 | http://purl.obolibrary.org/obo/OGG_0000000002 | denotes | gene |
| T126 | 840-841 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T97 | 0-166 | Sentence | denotes | We realised soon that the SARS-CoV E gene assay was more sensitive than the two RdRp gene assays combined with the one-step RT-PCR system available in our laboratory. |
| T98 | 167-266 | Sentence | denotes | However, our E gene assay showed high background levels hampering a clear evaluation of the assays. |
| T99 | 267-395 | Sentence | denotes | Each mastermix has its own proprietary composition, which may explain the differences in the performance of a certain PCR assay. |
| T100 | 396-560 | Sentence | denotes | Using commercial kits with optimised target regions and primer sequences (in the E gene and SARS-CoV-2-specific S gene) ruled out the unspecific signals completely. |
| T101 | 561-871 | Sentence | denotes | Hence, reasons for the observed unspecific signals may be dimerisation of primers and probes and/or unspecific primer binding and polymerase activity in the targeted region of the E gene, probably also depending on thermal profile and cycler-specific differences, or most likely a combination of these factors. |