PMC:7068162 / 6808-8118 JSONTXT

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    LitCovid-PubTator

    {"project":"LitCovid-PubTator","denotations":[{"id":"110","span":{"begin":231,"end":242},"obj":"Species"},{"id":"111","span":{"begin":258,"end":268},"obj":"Species"},{"id":"112","span":{"begin":272,"end":281},"obj":"Species"},{"id":"113","span":{"begin":285,"end":298},"obj":"Species"},{"id":"114","span":{"begin":312,"end":333},"obj":"Species"},{"id":"115","span":{"begin":488,"end":518},"obj":"Species"},{"id":"116","span":{"begin":547,"end":571},"obj":"Species"},{"id":"117","span":{"begin":575,"end":596},"obj":"Species"},{"id":"118","span":{"begin":805,"end":814},"obj":"Species"},{"id":"119","span":{"begin":818,"end":827},"obj":"Species"},{"id":"120","span":{"begin":831,"end":840},"obj":"Species"},{"id":"121","span":{"begin":844,"end":852},"obj":"Species"},{"id":"122","span":{"begin":856,"end":874},"obj":"Species"},{"id":"123","span":{"begin":878,"end":895},"obj":"Species"},{"id":"124","span":{"begin":899,"end":913},"obj":"Species"},{"id":"125","span":{"begin":917,"end":927},"obj":"Species"},{"id":"126","span":{"begin":931,"end":952},"obj":"Species"},{"id":"127","span":{"begin":532,"end":543},"obj":"Species"},{"id":"128","span":{"begin":600,"end":683},"obj":"Disease"},{"id":"129","span":{"begin":789,"end":797},"obj":"Disease"},{"id":"133","span":{"begin":36,"end":46},"obj":"Species"},{"id":"134","span":{"begin":79,"end":90},"obj":"Species"},{"id":"135","span":{"begin":157,"end":179},"obj":"Disease"},{"id":"137","span":{"begin":1072,"end":1089},"obj":"Species"},{"id":"140","span":{"begin":1108,"end":1111},"obj":"Gene"},{"id":"141","span":{"begin":1246,"end":1260},"obj":"Disease"}],"attributes":[{"id":"A110","pred":"tao:has_database_id","subj":"110","obj":"Tax:11118"},{"id":"A111","pred":"tao:has_database_id","subj":"111","obj":"Tax:290028"},{"id":"A112","pred":"tao:has_database_id","subj":"112","obj":"Tax:277944"},{"id":"A113","pred":"tao:has_database_id","subj":"113","obj":"Tax:10515"},{"id":"A114","pred":"tao:has_database_id","subj":"114","obj":"Tax:162145"},{"id":"A115","pred":"tao:has_database_id","subj":"115","obj":"Tax:1439707"},{"id":"A116","pred":"tao:has_database_id","subj":"116","obj":"Tax:83558"},{"id":"A117","pred":"tao:has_database_id","subj":"117","obj":"Tax:2104"},{"id":"A118","pred":"tao:has_database_id","subj":"118","obj":"Tax:11137"},{"id":"A119","pred":"tao:has_database_id","subj":"119","obj":"Tax:277944"},{"id":"A120","pred":"tao:has_database_id","subj":"120","obj":"Tax:31631"},{"id":"A121","pred":"tao:has_database_id","subj":"121","obj":"Tax:1335626"},{"id":"A122","pred":"tao:has_database_id","subj":"122","obj":"Tax:12069"},{"id":"A123","pred":"tao:has_database_id","subj":"123","obj":"Tax:12072"},{"id":"A124","pred":"tao:has_database_id","subj":"124","obj":"Tax:42789"},{"id":"A125","pred":"tao:has_database_id","subj":"125","obj":"Tax:12059"},{"id":"A126","pred":"tao:has_database_id","subj":"126","obj":"Tax:162145"},{"id":"A127","pred":"tao:has_database_id","subj":"127","obj":"Tax:42789"},{"id":"A128","pred":"tao:has_database_id","subj":"128","obj":"MESH:D014917"},{"id":"A129","pred":"tao:has_database_id","subj":"129","obj":"MESH:D007239"},{"id":"A133","pred":"tao:has_database_id","subj":"133","obj":"Tax:2697049"},{"id":"A134","pred":"tao:has_database_id","subj":"134","obj":"Tax:12814"},{"id":"A135","pred":"tao:has_database_id","subj":"135","obj":"MESH:D012141"},{"id":"A137","pred":"tao:has_database_id","subj":"137","obj":"Tax:694448"},{"id":"A140","pred":"tao:has_database_id","subj":"140","obj":"Gene:23498"},{"id":"A141","pred":"tao:has_database_id","subj":"141","obj":"MESH:D001102"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Table 2 Potential cross-reactivity SARS-CoV-2 Utility Channel test with other respiratory pathogens, evaluated with a panel of organisms typically found in respiratory infections\nClinical samples with known viruses Number tested\nCoronavirus (not typed) 5\nhCoV HKU-1 2\nhCoV NL63 1\nAdenovirus 2\nBocavirus 7\nHuman metapneumovirus 6\nInfluenza A 7\nInfluenza A(H1N1) 6\nInfluenza B 3\nParainfluenza 1 virus 3\nParainfluenza 2 virus 1\nParainfluenza 3 virus 8\nParainfluenza 4 virus 3\nRespiratory syncytial virus (A/B) 10\nRhino/enterovirus 8\nChlamydophila pneumoniae 4\nMycoplasma pneumoniae 4\nLegionella pneumophila 3\nBordetella pertussis 4\nBordetella parapertussis 1\nTotal number of clinical samples 88\nExternal quality control assessment panel with known viruses (lysates of infected cells)\nhCoV 229E 1\nhCoV NL63 1\nhCoV OC43 3\nMERS-CoV 4\nCoxsackievirus A21 1\nCoxsackievirus B3 1\nEnterovirus 68 1\nRhinovirus 3\nHuman metapneumovirus 3\nVirus-negative 4\nTotal number of quality control assessment panel samples 22\nTotal number of samples 110\nhCoV: human coronavirus;\nClinical samples had been pre-analysed by routine diagnostic. External quality control assessment panel (INSTAND) samples contained inactivated lysates of virus infected cells including four virus-negative cell lysates."}

    LitCovid-PD-FMA-UBERON

    {"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T21","span":{"begin":798,"end":803},"obj":"Body_part"},{"id":"T22","span":{"begin":1261,"end":1266},"obj":"Body_part"},{"id":"T23","span":{"begin":1297,"end":1301},"obj":"Body_part"}],"attributes":[{"id":"A21","pred":"fma_id","subj":"T21","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A22","pred":"fma_id","subj":"T22","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A23","pred":"fma_id","subj":"T23","obj":"http://purl.org/sig/ont/fma/fma68646"}],"text":"Table 2 Potential cross-reactivity SARS-CoV-2 Utility Channel test with other respiratory pathogens, evaluated with a panel of organisms typically found in respiratory infections\nClinical samples with known viruses Number tested\nCoronavirus (not typed) 5\nhCoV HKU-1 2\nhCoV NL63 1\nAdenovirus 2\nBocavirus 7\nHuman metapneumovirus 6\nInfluenza A 7\nInfluenza A(H1N1) 6\nInfluenza B 3\nParainfluenza 1 virus 3\nParainfluenza 2 virus 1\nParainfluenza 3 virus 8\nParainfluenza 4 virus 3\nRespiratory syncytial virus (A/B) 10\nRhino/enterovirus 8\nChlamydophila pneumoniae 4\nMycoplasma pneumoniae 4\nLegionella pneumophila 3\nBordetella pertussis 4\nBordetella parapertussis 1\nTotal number of clinical samples 88\nExternal quality control assessment panel with known viruses (lysates of infected cells)\nhCoV 229E 1\nhCoV NL63 1\nhCoV OC43 3\nMERS-CoV 4\nCoxsackievirus A21 1\nCoxsackievirus B3 1\nEnterovirus 68 1\nRhinovirus 3\nHuman metapneumovirus 3\nVirus-negative 4\nTotal number of quality control assessment panel samples 22\nTotal number of samples 110\nhCoV: human coronavirus;\nClinical samples had been pre-analysed by routine diagnostic. External quality control assessment panel (INSTAND) samples contained inactivated lysates of virus infected cells including four virus-negative cell lysates."}

    LitCovid-PD-MONDO

    {"project":"LitCovid-PD-MONDO","denotations":[{"id":"T28","span":{"begin":36,"end":44},"obj":"Disease"},{"id":"T29","span":{"begin":157,"end":179},"obj":"Disease"},{"id":"T30","span":{"begin":337,"end":346},"obj":"Disease"},{"id":"T31","span":{"begin":352,"end":369},"obj":"Disease"},{"id":"T32","span":{"begin":373,"end":382},"obj":"Disease"},{"id":"T33","span":{"begin":561,"end":571},"obj":"Disease"},{"id":"T34","span":{"begin":575,"end":596},"obj":"Disease"},{"id":"T35","span":{"begin":600,"end":610},"obj":"Disease"},{"id":"T36","span":{"begin":637,"end":646},"obj":"Disease"}],"attributes":[{"id":"A28","pred":"mondo_id","subj":"T28","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A29","pred":"mondo_id","subj":"T29","obj":"http://purl.obolibrary.org/obo/MONDO_0024355"},{"id":"A30","pred":"mondo_id","subj":"T30","obj":"http://purl.obolibrary.org/obo/MONDO_0005812"},{"id":"A31","pred":"mondo_id","subj":"T31","obj":"http://purl.obolibrary.org/obo/MONDO_0005460"},{"id":"A32","pred":"mondo_id","subj":"T32","obj":"http://purl.obolibrary.org/obo/MONDO_0005812"},{"id":"A33","pred":"mondo_id","subj":"T33","obj":"http://purl.obolibrary.org/obo/MONDO_0005249"},{"id":"A34","pred":"mondo_id","subj":"T34","obj":"http://purl.obolibrary.org/obo/MONDO_0005867"},{"id":"A35","pred":"mondo_id","subj":"T35","obj":"http://purl.obolibrary.org/obo/MONDO_0005824"},{"id":"A36","pred":"mondo_id","subj":"T36","obj":"http://purl.obolibrary.org/obo/MONDO_0005077"}],"text":"Table 2 Potential cross-reactivity SARS-CoV-2 Utility Channel test with other respiratory pathogens, evaluated with a panel of organisms typically found in respiratory infections\nClinical samples with known viruses Number tested\nCoronavirus (not typed) 5\nhCoV HKU-1 2\nhCoV NL63 1\nAdenovirus 2\nBocavirus 7\nHuman metapneumovirus 6\nInfluenza A 7\nInfluenza A(H1N1) 6\nInfluenza B 3\nParainfluenza 1 virus 3\nParainfluenza 2 virus 1\nParainfluenza 3 virus 8\nParainfluenza 4 virus 3\nRespiratory syncytial virus (A/B) 10\nRhino/enterovirus 8\nChlamydophila pneumoniae 4\nMycoplasma pneumoniae 4\nLegionella pneumophila 3\nBordetella pertussis 4\nBordetella parapertussis 1\nTotal number of clinical samples 88\nExternal quality control assessment panel with known viruses (lysates of infected cells)\nhCoV 229E 1\nhCoV NL63 1\nhCoV OC43 3\nMERS-CoV 4\nCoxsackievirus A21 1\nCoxsackievirus B3 1\nEnterovirus 68 1\nRhinovirus 3\nHuman metapneumovirus 3\nVirus-negative 4\nTotal number of quality control assessment panel samples 22\nTotal number of samples 110\nhCoV: human coronavirus;\nClinical samples had been pre-analysed by routine diagnostic. External quality control assessment panel (INSTAND) samples contained inactivated lysates of virus infected cells including four virus-negative cell lysates."}

    LitCovid-PD-CLO

    {"project":"LitCovid-PD-CLO","denotations":[{"id":"T55","span":{"begin":63,"end":67},"obj":"http://purl.obolibrary.org/obo/UBERON_0000473"},{"id":"T56","span":{"begin":117,"end":118},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T57","span":{"begin":128,"end":137},"obj":"http://purl.obolibrary.org/obo/OBI_0100026"},{"id":"T58","span":{"begin":128,"end":137},"obj":"http://purl.obolibrary.org/obo/UBERON_0000468"},{"id":"T59","span":{"begin":208,"end":215},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T60","span":{"begin":224,"end":230},"obj":"http://purl.obolibrary.org/obo/UBERON_0000473"},{"id":"T61","span":{"begin":312,"end":317},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T62","span":{"begin":347,"end":351},"obj":"http://purl.obolibrary.org/obo/CLO_0001608"},{"id":"T63","span":{"begin":362,"end":363},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T64","span":{"begin":383,"end":387},"obj":"http://purl.obolibrary.org/obo/CLO_0001812"},{"id":"T65","span":{"begin":404,"end":409},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T66","span":{"begin":429,"end":434},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T67","span":{"begin":454,"end":459},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T68","span":{"begin":479,"end":484},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T69","span":{"begin":510,"end":515},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T70","span":{"begin":517,"end":518},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T71","span":{"begin":519,"end":520},"obj":"http://purl.obolibrary.org/obo/CLO_0001021"},{"id":"T72","span":{"begin":769,"end":776},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T73","span":{"begin":798,"end":803},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T74","span":{"begin":871,"end":874},"obj":"http://purl.obolibrary.org/obo/CLO_0053711"},{"id":"T75","span":{"begin":893,"end":895},"obj":"http://purl.obolibrary.org/obo/CLO_0001812"},{"id":"T76","span":{"begin":931,"end":936},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T77","span":{"begin":956,"end":961},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T78","span":{"begin":1033,"end":1035},"obj":"http://purl.obolibrary.org/obo/CLO_0050507"},{"id":"T79","span":{"begin":1072,"end":1077},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T80","span":{"begin":1246,"end":1251},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T81","span":{"begin":1261,"end":1266},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T82","span":{"begin":1282,"end":1287},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T83","span":{"begin":1297,"end":1301},"obj":"http://purl.obolibrary.org/obo/GO_0005623"}],"text":"Table 2 Potential cross-reactivity SARS-CoV-2 Utility Channel test with other respiratory pathogens, evaluated with a panel of organisms typically found in respiratory infections\nClinical samples with known viruses Number tested\nCoronavirus (not typed) 5\nhCoV HKU-1 2\nhCoV NL63 1\nAdenovirus 2\nBocavirus 7\nHuman metapneumovirus 6\nInfluenza A 7\nInfluenza A(H1N1) 6\nInfluenza B 3\nParainfluenza 1 virus 3\nParainfluenza 2 virus 1\nParainfluenza 3 virus 8\nParainfluenza 4 virus 3\nRespiratory syncytial virus (A/B) 10\nRhino/enterovirus 8\nChlamydophila pneumoniae 4\nMycoplasma pneumoniae 4\nLegionella pneumophila 3\nBordetella pertussis 4\nBordetella parapertussis 1\nTotal number of clinical samples 88\nExternal quality control assessment panel with known viruses (lysates of infected cells)\nhCoV 229E 1\nhCoV NL63 1\nhCoV OC43 3\nMERS-CoV 4\nCoxsackievirus A21 1\nCoxsackievirus B3 1\nEnterovirus 68 1\nRhinovirus 3\nHuman metapneumovirus 3\nVirus-negative 4\nTotal number of quality control assessment panel samples 22\nTotal number of samples 110\nhCoV: human coronavirus;\nClinical samples had been pre-analysed by routine diagnostic. External quality control assessment panel (INSTAND) samples contained inactivated lysates of virus infected cells including four virus-negative cell lysates."}

    LitCovid-sentences

    {"project":"LitCovid-sentences","denotations":[{"id":"T58","span":{"begin":0,"end":179},"obj":"Sentence"},{"id":"T59","span":{"begin":180,"end":230},"obj":"Sentence"},{"id":"T60","span":{"begin":231,"end":257},"obj":"Sentence"},{"id":"T61","span":{"begin":258,"end":271},"obj":"Sentence"},{"id":"T62","span":{"begin":272,"end":284},"obj":"Sentence"},{"id":"T63","span":{"begin":285,"end":298},"obj":"Sentence"},{"id":"T64","span":{"begin":299,"end":311},"obj":"Sentence"},{"id":"T65","span":{"begin":312,"end":336},"obj":"Sentence"},{"id":"T66","span":{"begin":337,"end":351},"obj":"Sentence"},{"id":"T67","span":{"begin":352,"end":372},"obj":"Sentence"},{"id":"T68","span":{"begin":373,"end":387},"obj":"Sentence"},{"id":"T69","span":{"begin":388,"end":412},"obj":"Sentence"},{"id":"T70","span":{"begin":413,"end":437},"obj":"Sentence"},{"id":"T71","span":{"begin":438,"end":462},"obj":"Sentence"},{"id":"T72","span":{"begin":463,"end":487},"obj":"Sentence"},{"id":"T73","span":{"begin":488,"end":525},"obj":"Sentence"},{"id":"T74","span":{"begin":526,"end":546},"obj":"Sentence"},{"id":"T75","span":{"begin":547,"end":574},"obj":"Sentence"},{"id":"T76","span":{"begin":575,"end":599},"obj":"Sentence"},{"id":"T77","span":{"begin":600,"end":625},"obj":"Sentence"},{"id":"T78","span":{"begin":626,"end":649},"obj":"Sentence"},{"id":"T79","span":{"begin":650,"end":677},"obj":"Sentence"},{"id":"T80","span":{"begin":678,"end":715},"obj":"Sentence"},{"id":"T81","span":{"begin":716,"end":804},"obj":"Sentence"},{"id":"T82","span":{"begin":805,"end":817},"obj":"Sentence"},{"id":"T83","span":{"begin":818,"end":830},"obj":"Sentence"},{"id":"T84","span":{"begin":831,"end":843},"obj":"Sentence"},{"id":"T85","span":{"begin":844,"end":855},"obj":"Sentence"},{"id":"T86","span":{"begin":856,"end":877},"obj":"Sentence"},{"id":"T87","span":{"begin":878,"end":898},"obj":"Sentence"},{"id":"T88","span":{"begin":899,"end":916},"obj":"Sentence"},{"id":"T89","span":{"begin":917,"end":930},"obj":"Sentence"},{"id":"T90","span":{"begin":931,"end":955},"obj":"Sentence"},{"id":"T91","span":{"begin":956,"end":973},"obj":"Sentence"},{"id":"T92","span":{"begin":974,"end":1035},"obj":"Sentence"},{"id":"T93","span":{"begin":1036,"end":1065},"obj":"Sentence"},{"id":"T94","span":{"begin":1066,"end":1090},"obj":"Sentence"},{"id":"T95","span":{"begin":1091,"end":1152},"obj":"Sentence"},{"id":"T96","span":{"begin":1153,"end":1310},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Table 2 Potential cross-reactivity SARS-CoV-2 Utility Channel test with other respiratory pathogens, evaluated with a panel of organisms typically found in respiratory infections\nClinical samples with known viruses Number tested\nCoronavirus (not typed) 5\nhCoV HKU-1 2\nhCoV NL63 1\nAdenovirus 2\nBocavirus 7\nHuman metapneumovirus 6\nInfluenza A 7\nInfluenza A(H1N1) 6\nInfluenza B 3\nParainfluenza 1 virus 3\nParainfluenza 2 virus 1\nParainfluenza 3 virus 8\nParainfluenza 4 virus 3\nRespiratory syncytial virus (A/B) 10\nRhino/enterovirus 8\nChlamydophila pneumoniae 4\nMycoplasma pneumoniae 4\nLegionella pneumophila 3\nBordetella pertussis 4\nBordetella parapertussis 1\nTotal number of clinical samples 88\nExternal quality control assessment panel with known viruses (lysates of infected cells)\nhCoV 229E 1\nhCoV NL63 1\nhCoV OC43 3\nMERS-CoV 4\nCoxsackievirus A21 1\nCoxsackievirus B3 1\nEnterovirus 68 1\nRhinovirus 3\nHuman metapneumovirus 3\nVirus-negative 4\nTotal number of quality control assessment panel samples 22\nTotal number of samples 110\nhCoV: human coronavirus;\nClinical samples had been pre-analysed by routine diagnostic. External quality control assessment panel (INSTAND) samples contained inactivated lysates of virus infected cells including four virus-negative cell lysates."}

    LitCovid-PD-HP

    {"project":"LitCovid-PD-HP","denotations":[{"id":"T3","span":{"begin":157,"end":179},"obj":"Phenotype"},{"id":"T4","span":{"begin":561,"end":571},"obj":"Phenotype"},{"id":"T5","span":{"begin":586,"end":596},"obj":"Phenotype"}],"attributes":[{"id":"A3","pred":"hp_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/HP_0011947"},{"id":"A4","pred":"hp_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/HP_0002090"},{"id":"A5","pred":"hp_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/HP_0002090"}],"text":"Table 2 Potential cross-reactivity SARS-CoV-2 Utility Channel test with other respiratory pathogens, evaluated with a panel of organisms typically found in respiratory infections\nClinical samples with known viruses Number tested\nCoronavirus (not typed) 5\nhCoV HKU-1 2\nhCoV NL63 1\nAdenovirus 2\nBocavirus 7\nHuman metapneumovirus 6\nInfluenza A 7\nInfluenza A(H1N1) 6\nInfluenza B 3\nParainfluenza 1 virus 3\nParainfluenza 2 virus 1\nParainfluenza 3 virus 8\nParainfluenza 4 virus 3\nRespiratory syncytial virus (A/B) 10\nRhino/enterovirus 8\nChlamydophila pneumoniae 4\nMycoplasma pneumoniae 4\nLegionella pneumophila 3\nBordetella pertussis 4\nBordetella parapertussis 1\nTotal number of clinical samples 88\nExternal quality control assessment panel with known viruses (lysates of infected cells)\nhCoV 229E 1\nhCoV NL63 1\nhCoV OC43 3\nMERS-CoV 4\nCoxsackievirus A21 1\nCoxsackievirus B3 1\nEnterovirus 68 1\nRhinovirus 3\nHuman metapneumovirus 3\nVirus-negative 4\nTotal number of quality control assessment panel samples 22\nTotal number of samples 110\nhCoV: human coronavirus;\nClinical samples had been pre-analysed by routine diagnostic. External quality control assessment panel (INSTAND) samples contained inactivated lysates of virus infected cells including four virus-negative cell lysates."}