PMC:7067204 / 20243-20484 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"1189","span":{"begin":109,"end":111},"obj":"Gene"},{"id":"1195","span":{"begin":223,"end":227},"obj":"Gene"},{"id":"1206","span":{"begin":228,"end":230},"obj":"Gene"},{"id":"1247","span":{"begin":64,"end":72},"obj":"Species"},{"id":"1248","span":{"begin":231,"end":240},"obj":"Species"}],"attributes":[{"id":"A1189","pred":"tao:has_database_id","subj":"1189","obj":"Gene:6999"},{"id":"A1195","pred":"tao:has_database_id","subj":"1195","obj":"Gene:43740577"},{"id":"A1206","pred":"tao:has_database_id","subj":"1206","obj":"Gene:6688"},{"id":"A1247","pred":"tao:has_database_id","subj":"1247","obj":"Tax:694009"},{"id":"A1248","pred":"tao:has_database_id","subj":"1248","obj":"Tax:2697049"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"An aggregation motif VLVVL (amino acid 75–79) has been found in SARS-CoV orf8b (Figure 5(B)) which was shown to trigger intracellular stress pathways and activates NLRP3 inflammasomes [26], but this is absent in this novel orf8 of 2019-nCoV."}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T96","span":{"begin":28,"end":38},"obj":"Body_part"}],"attributes":[{"id":"A96","pred":"fma_id","subj":"T96","obj":"http://purl.org/sig/ont/fma/fma82739"}],"text":"An aggregation motif VLVVL (amino acid 75–79) has been found in SARS-CoV orf8b (Figure 5(B)) which was shown to trigger intracellular stress pathways and activates NLRP3 inflammasomes [26], but this is absent in this novel orf8 of 2019-nCoV."}

{"project":"LitCovid_AGAC","denotations":[{"id":"p12770s30","span":{"begin":112,"end":119},"obj":"PosReg"},{"id":"p12770s31","span":{"begin":120,"end":133},"obj":"CPA"},{"id":"p12770s35","span":{"begin":154,"end":163},"obj":"PosReg"},{"id":"p12770s37","span":{"begin":170,"end":183},"obj":"MPA"}],"text":"An aggregation motif VLVVL (amino acid 75–79) has been found in SARS-CoV orf8b (Figure 5(B)) which was shown to trigger intracellular stress pathways and activates NLRP3 inflammasomes [26], but this is absent in this novel orf8 of 2019-nCoV."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T104","span":{"begin":64,"end":72},"obj":"Disease"}],"attributes":[{"id":"A104","pred":"mondo_id","subj":"T104","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"An aggregation motif VLVVL (amino acid 75–79) has been found in SARS-CoV orf8b (Figure 5(B)) which was shown to trigger intracellular stress pathways and activates NLRP3 inflammasomes [26], but this is absent in this novel orf8 of 2019-nCoV."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T239","span":{"begin":46,"end":49},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T240","span":{"begin":89,"end":90},"obj":"http://purl.obolibrary.org/obo/CLO_0001021"},{"id":"T241","span":{"begin":154,"end":163},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"}],"text":"An aggregation motif VLVVL (amino acid 75–79) has been found in SARS-CoV orf8b (Figure 5(B)) which was shown to trigger intracellular stress pathways and activates NLRP3 inflammasomes [26], but this is absent in this novel orf8 of 2019-nCoV."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T130","span":{"begin":28,"end":38},"obj":"Chemical"},{"id":"T131","span":{"begin":28,"end":33},"obj":"Chemical"},{"id":"T132","span":{"begin":34,"end":38},"obj":"Chemical"}],"attributes":[{"id":"A130","pred":"chebi_id","subj":"T130","obj":"http://purl.obolibrary.org/obo/CHEBI_33709"},{"id":"A131","pred":"chebi_id","subj":"T131","obj":"http://purl.obolibrary.org/obo/CHEBI_46882"},{"id":"A132","pred":"chebi_id","subj":"T132","obj":"http://purl.obolibrary.org/obo/CHEBI_37527"}],"text":"An aggregation motif VLVVL (amino acid 75–79) has been found in SARS-CoV orf8b (Figure 5(B)) which was shown to trigger intracellular stress pathways and activates NLRP3 inflammasomes [26], but this is absent in this novel orf8 of 2019-nCoV."}

{"project":"LitCovid-sentences","denotations":[{"id":"T206","span":{"begin":0,"end":241},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"An aggregation motif VLVVL (amino acid 75–79) has been found in SARS-CoV orf8b (Figure 5(B)) which was shown to trigger intracellular stress pathways and activates NLRP3 inflammasomes [26], but this is absent in this novel orf8 of 2019-nCoV."}

{"project":"2_test","denotations":[{"id":"31987001-31231549-27754494","span":{"begin":185,"end":187},"obj":"31231549"}],"text":"An aggregation motif VLVVL (amino acid 75–79) has been found in SARS-CoV orf8b (Figure 5(B)) which was shown to trigger intracellular stress pathways and activates NLRP3 inflammasomes [26], but this is absent in this novel orf8 of 2019-nCoV."}

{"project":"MyTest","denotations":[{"id":"31987001-31231549-27754494","span":{"begin":185,"end":187},"obj":"31231549"}],"namespaces":[{"prefix":"_base","uri":"https://www.uniprot.org/uniprot/testbase"},{"prefix":"UniProtKB","uri":"https://www.uniprot.org/uniprot/"},{"prefix":"uniprot","uri":"https://www.uniprot.org/uniprotkb/"}],"text":"An aggregation motif VLVVL (amino acid 75–79) has been found in SARS-CoV orf8b (Figure 5(B)) which was shown to trigger intracellular stress pathways and activates NLRP3 inflammasomes [26], but this is absent in this novel orf8 of 2019-nCoV."}