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PMC:7067204 / 16955-18513 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
957 1419-1421 Gene denotes of Gene:6688
958 1387-1389 Gene denotes of Gene:6688
959 1453-1462 Species denotes 2019-nCoV Tax:2697049
960 1478-1486 Species denotes SARS-CoV Tax:694009
961 1491-1507 Species denotes SARS-related CoV Tax:694009
991 505-507 Gene denotes as Gene:112935892
992 1148-1150 Gene denotes of Gene:6688
993 1223-1226 Gene denotes bat Gene:570
994 747-750 Gene denotes bat Gene:570
995 496-498 Gene denotes as Gene:112935892
996 1277-1280 Gene denotes The Gene:25085
997 1151-1154 Gene denotes the Gene:25085
998 815-818 Gene denotes the Gene:25085
999 629-631 Gene denotes to Gene:6999
1000 227-229 Gene denotes to Gene:6999
1001 209-211 Gene denotes to Gene:6999
1002 62-64 Gene denotes to Gene:6999
1003 86-90 Gene denotes SARS Gene:6301
1004 1292-1294 Gene denotes of Gene:6688
1005 858-860 Gene denotes of Gene:6688
1006 651-653 Gene denotes of Gene:6688
1007 236-238 Gene denotes of Gene:6688
1008 74-82 Species denotes SARS-CoV Tax:694009
1009 93-96 Species denotes CoV Tax:11118
1010 159-167 Species denotes SARS-CoV Tax:694009
1011 751-767 Species denotes SARS-related-CoV Tax:694009
1012 861-869 Species denotes SARS-CoV Tax:694009
1013 931-947 Species denotes SARS-related-CoV Tax:694009
1014 1227-1243 Species denotes SARS-related-CoV Tax:694009
1015 1315-1324 Species denotes 2019-nCoV Tax:2697049
1016 487-495 Disease denotes necrosis MESH:D009336
1017 558-566 Disease denotes necrosis MESH:D009336
1018 409-411 CellLine denotes E6 CVCL:4582
1019 420-424 CellLine denotes 293T CVCL:0063

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T81 23-30 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T82 97-104 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T83 266-270 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T84 425-430 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T85 821-837 Body_part denotes terminal nucleus http://purl.org/sig/ont/fma/fma54529
T86 1062-1070 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T87 1155-1164 Body_part denotes protein's http://purl.org/sig/ont/fma/fma67257
T88 1304-1311 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T89 1428-1435 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T90 1535-1542 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257

LitCovid_AGAC

Id Subject Object Predicate Lexical cue
p12744s11 199-208 CPA denotes replicate

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T75 74-82 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T76 86-90 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T77 159-167 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T78 751-755 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T79 861-869 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T80 931-935 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T81 1227-1231 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T82 1478-1486 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T83 1491-1495 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T194 0-1 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T195 249-254 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T196 266-276 http://purl.obolibrary.org/obo/CL_0000000 denotes cell types
T197 371-372 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T198 404-408 http://purl.obolibrary.org/obo/CLO_0009524 denotes Vero
T199 404-408 http://purl.obolibrary.org/obo/CLO_0050515 denotes Vero
T200 420-424 http://purl.obolibrary.org/obo/CLO_0050894 denotes 293T
T201 420-424 http://purl.obolibrary.org/obo/CLO_0051650 denotes 293T
T202 420-424 http://purl.obolibrary.org/obo/CLO_0052052 denotes 293T
T203 425-430 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T204 448-449 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T205 677-687 http://purl.obolibrary.org/obo/SO_0000418 denotes signalling
T206 747-750 http://purl.obolibrary.org/obo/NCBITaxon_9397 denotes bat
T207 851-857 http://purl.obolibrary.org/obo/SO_0000418 denotes signal
T208 871-873 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T209 891-899 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T210 1005-1015 http://purl.obolibrary.org/obo/CLO_0001658 denotes activities
T211 1104-1114 http://purl.obolibrary.org/obo/CLO_0001658 denotes activities
T212 1198-1199 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T213 1223-1226 http://purl.obolibrary.org/obo/NCBITaxon_9397 denotes bat
T214 1397-1398 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T215 1509-1510 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T216 1512-1513 http://purl.obolibrary.org/obo/CLO_0001020 denotes A

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T112 23-30 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T113 97-104 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T114 830-837 Chemical denotes nucleus http://purl.obolibrary.org/obo/CHEBI_33252
T115 880-890 Chemical denotes antagonist http://purl.obolibrary.org/obo/CHEBI_48706
T116 974-984 Chemical denotes antagonist http://purl.obolibrary.org/obo/CHEBI_48706
T117 1062-1070 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T118 1093-1103 Chemical denotes antagonist http://purl.obolibrary.org/obo/CHEBI_48706
T119 1304-1311 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T120 1428-1435 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T121 1535-1542 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T10 324-341 http://purl.obolibrary.org/obo/GO_0019079 denotes viral replication
T11 324-341 http://purl.obolibrary.org/obo/GO_0019058 denotes viral replication
T12 487-495 http://purl.obolibrary.org/obo/GO_0070265 denotes necrosis
T13 487-495 http://purl.obolibrary.org/obo/GO_0019835 denotes necrosis
T14 487-495 http://purl.obolibrary.org/obo/GO_0008219 denotes necrosis
T15 487-495 http://purl.obolibrary.org/obo/GO_0001906 denotes necrosis
T16 558-566 http://purl.obolibrary.org/obo/GO_0070265 denotes necrosis
T17 558-566 http://purl.obolibrary.org/obo/GO_0019835 denotes necrosis
T18 558-566 http://purl.obolibrary.org/obo/GO_0008219 denotes necrosis
T19 558-566 http://purl.obolibrary.org/obo/GO_0001906 denotes necrosis
T20 571-580 http://purl.obolibrary.org/obo/GO_0097194 denotes apoptosis
T21 571-580 http://purl.obolibrary.org/obo/GO_0006915 denotes apoptosis
T22 663-672 http://purl.obolibrary.org/obo/GO_0009058 denotes synthesis
T23 677-687 http://purl.obolibrary.org/obo/GO_0023052 denotes signalling
T24 830-850 http://purl.obolibrary.org/obo/GO_0051647 denotes nucleus localization
T25 838-850 http://purl.obolibrary.org/obo/GO_0051179 denotes localization
T26 1173-1185 http://purl.obolibrary.org/obo/GO_0051179 denotes localization
T27 1263-1275 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T182 0-139 Sentence denotes A novel short putative protein with 4 helices and no homology to existing SARS-CoV or SARS-r-CoV protein was found within Orf3b (Figure 4).
T183 140-351 Sentence denotes It is notable that SARS-CoV deletion mutants lacking orf3b replicate to levels similar to those of wild-type virus in several cell types [19], suggesting that orf3b is dispensable for viral replication in vitro.
T184 352-607 Sentence denotes But orf3b may have a role in viral pathogenicity as Vero E6 but not 293T cells transfected with a construct expressing Orf3b underwent necrosis as early as 6 h after transfection and underwent simultaneous necrosis and apoptosis at later time points [20].
T185 608-693 Sentence denotes Orf3b was also shown to inhibit expression of IFN-β at synthesis and signalling [21].
T186 694-875 Sentence denotes Subsequently, orf3b homologues identified from three bat SARS-related-CoV strains were C-terminally truncated and lacked the C-terminal nucleus localization signal of SARS-CoV [22].
T187 876-1016 Sentence denotes IFN antagonist activity analysis demonstrated that one SARS-related-CoV orf3b still possessed IFN antagonist and IRF3-modulating activities.
T188 1017-1276 Sentence denotes These results indicated that different orf3b proteins display different IFN antagonist activities and this function is independent of the protein's nuclear localization, suggesting a potential link between bat SARS-related-CoV orf3b function and pathogenesis.
T189 1277-1367 Sentence denotes The importance of this new protein in 2019-nCoV will require further validation and study.
T190 1368-1377 Sentence denotes Figure 4.
T191 1378-1396 Sentence denotes Analysis of orf3b.
T192 1397-1399 Sentence denotes A.
T193 1400-1508 Sentence denotes Multiple alignment of orf3b protein sequence between 2019-nCoV (HKU-SZ-005b), SARS-CoV and SARS-related CoV.
T194 1509-1511 Sentence denotes B.
T195 1512-1558 Sentence denotes A novel putative short protein found in orf3b.

2_test

Id Subject Object Predicate Lexical cue
31987001-16282490-27754487 278-280 16282490 denotes 19
31987001-16965829-27754488 603-605 16965829 denotes 20
31987001-17108024-27754489 689-691 17108024 denotes 21
31987001-22012463-27754490 871-873 22012463 denotes 22

MyTest

Id Subject Object Predicate Lexical cue
31987001-16282490-27754487 278-280 16282490 denotes 19
31987001-16965829-27754488 603-605 16965829 denotes 20
31987001-17108024-27754489 689-691 17108024 denotes 21
31987001-22012463-27754490 871-873 22012463 denotes 22