PMC:7054935 / 4597-5016 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"172","span":{"begin":124,"end":129},"obj":"Species"},{"id":"173","span":{"begin":145,"end":149},"obj":"Species"}],"attributes":[{"id":"A172","pred":"tao:has_database_id","subj":"172","obj":"Tax:9606"},{"id":"A173","pred":"tao:has_database_id","subj":"173","obj":"Tax:10090"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Due to the elevated pathogenic activity of the SHC014-MA15 chimeric virus relative to MA15 chimeric virus with the original human SARS S gene in mice, such experiments with SL-SHC014-MA15 chimeric virus were later restricted as gain of function (GOF) studies under the US government-mandated pause policy (https://www.nih.gov/about-nih/who-we-are/nih-director/statements/nih-lifts-funding-pause-gain-function-research)."}

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T107","span":{"begin":68,"end":73},"obj":"NCBITaxon:10239"},{"id":"T106","span":{"begin":100,"end":105},"obj":"NCBITaxon:10239"},{"id":"T105","span":{"begin":124,"end":129},"obj":"SP_6;NCBITaxon:9606"},{"id":"T104","span":{"begin":130,"end":134},"obj":"SP_10;PR:000014459;PG_9"},{"id":"T103","span":{"begin":135,"end":136},"obj":"PG_9"},{"id":"T102","span":{"begin":137,"end":141},"obj":"SO:0000704"},{"id":"T101","span":{"begin":145,"end":149},"obj":"NCBITaxon:10088"},{"id":"T100","span":{"begin":197,"end":202},"obj":"NCBITaxon:10239"}],"text":"Due to the elevated pathogenic activity of the SHC014-MA15 chimeric virus relative to MA15 chimeric virus with the original human SARS S gene in mice, such experiments with SL-SHC014-MA15 chimeric virus were later restricted as gain of function (GOF) studies under the US government-mandated pause policy (https://www.nih.gov/about-nih/who-we-are/nih-director/statements/nih-lifts-funding-pause-gain-function-research)."}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T24","span":{"begin":137,"end":141},"obj":"Body_part"}],"attributes":[{"id":"A24","pred":"fma_id","subj":"T24","obj":"http://purl.org/sig/ont/fma/fma74402"}],"text":"Due to the elevated pathogenic activity of the SHC014-MA15 chimeric virus relative to MA15 chimeric virus with the original human SARS S gene in mice, such experiments with SL-SHC014-MA15 chimeric virus were later restricted as gain of function (GOF) studies under the US government-mandated pause policy (https://www.nih.gov/about-nih/who-we-are/nih-director/statements/nih-lifts-funding-pause-gain-function-research)."}

{"project":"LitCovid_AGAC","denotations":[{"id":"p9257s3","span":{"begin":11,"end":19},"obj":"PosReg"},{"id":"p9257s4","span":{"begin":20,"end":39},"obj":"CPA"}],"text":"Due to the elevated pathogenic activity of the SHC014-MA15 chimeric virus relative to MA15 chimeric virus with the original human SARS S gene in mice, such experiments with SL-SHC014-MA15 chimeric virus were later restricted as gain of function (GOF) studies under the US government-mandated pause policy (https://www.nih.gov/about-nih/who-we-are/nih-director/statements/nih-lifts-funding-pause-gain-function-research)."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T52","span":{"begin":130,"end":134},"obj":"Disease"}],"attributes":[{"id":"A52","pred":"mondo_id","subj":"T52","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"Due to the elevated pathogenic activity of the SHC014-MA15 chimeric virus relative to MA15 chimeric virus with the original human SARS S gene in mice, such experiments with SL-SHC014-MA15 chimeric virus were later restricted as gain of function (GOF) studies under the US government-mandated pause policy (https://www.nih.gov/about-nih/who-we-are/nih-director/statements/nih-lifts-funding-pause-gain-function-research)."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T79","span":{"begin":31,"end":39},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T80","span":{"begin":68,"end":73},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T81","span":{"begin":100,"end":105},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T82","span":{"begin":124,"end":129},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T83","span":{"begin":137,"end":141},"obj":"http://purl.obolibrary.org/obo/OGG_0000000002"},{"id":"T84","span":{"begin":197,"end":202},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"}],"text":"Due to the elevated pathogenic activity of the SHC014-MA15 chimeric virus relative to MA15 chimeric virus with the original human SARS S gene in mice, such experiments with SL-SHC014-MA15 chimeric virus were later restricted as gain of function (GOF) studies under the US government-mandated pause policy (https://www.nih.gov/about-nih/who-we-are/nih-director/statements/nih-lifts-funding-pause-gain-function-research)."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T12","span":{"begin":173,"end":175},"obj":"Chemical"}],"attributes":[{"id":"A12","pred":"chebi_id","subj":"T12","obj":"http://purl.obolibrary.org/obo/CHEBI_74815"}],"text":"Due to the elevated pathogenic activity of the SHC014-MA15 chimeric virus relative to MA15 chimeric virus with the original human SARS S gene in mice, such experiments with SL-SHC014-MA15 chimeric virus were later restricted as gain of function (GOF) studies under the US government-mandated pause policy (https://www.nih.gov/about-nih/who-we-are/nih-director/statements/nih-lifts-funding-pause-gain-function-research)."}

{"project":"LitCovid-sentences","denotations":[{"id":"T29","span":{"begin":0,"end":419},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Due to the elevated pathogenic activity of the SHC014-MA15 chimeric virus relative to MA15 chimeric virus with the original human SARS S gene in mice, such experiments with SL-SHC014-MA15 chimeric virus were later restricted as gain of function (GOF) studies under the US government-mandated pause policy (https://www.nih.gov/about-nih/who-we-are/nih-director/statements/nih-lifts-funding-pause-gain-function-research)."}