> top > docs > PMC:7054527 > spans > 2965-6327 > annotations

PMC:7054527 / 2965-6327 JSONTXT

Annnotations TAB JSON ListView MergeView

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
111 42-55 Species denotes Coronaviruses Tax:11118
112 80-93 Species denotes Coronaviridae Tax:11118
113 223-236 Species denotes coronaviruses Tax:11118
114 240-243 Species denotes CoV Tax:11118
115 245-250 Species denotes β-CoV Tax:694002
116 254-257 Species denotes CoV Tax:11118
117 265-268 Species denotes CoV Tax:11118
118 287-298 Species denotes coronavirus Tax:11118
119 336-341 Species denotes human Tax:9606
120 365-368 Species denotes CoV Tax:11118
121 373-378 Species denotes β-CoV Tax:694002
122 458-464 Species denotes humans Tax:9606
123 486-489 Species denotes CoV Tax:11118
124 496-499 Species denotes CoV Tax:11118
125 313-332 Disease denotes infectious diseases MESH:D003141
156 1577-1580 Gene denotes bat Gene:570
157 1472-1475 Gene denotes bat Gene:570
158 1311-1314 Gene denotes bat Gene:570
159 565-576 Species denotes coronavirus Tax:11118
160 611-617 Species denotes humans Tax:9606
161 628-636 Species denotes SARS-CoV Tax:694009
162 645-700 Species denotes Middle East respiratory syndrome coronavirus (MERS-CoV) Tax:1335626
163 801-809 Species denotes SARS-CoV Tax:694009
164 814-822 Species denotes MERS-CoV Tax:1335626
165 837-842 Species denotes β-CoV Tax:694002
166 849-858 Species denotes 2019-nCoV Tax:2697049
167 897-902 Species denotes β-CoV Tax:694002
168 1043-1052 Species denotes 2019-nCoV Tax:2697049
169 1057-1065 Species denotes SARS-CoV Tax:694009
170 1081-1089 Species denotes MERS-CoV Tax:1335626
171 1103-1112 Species denotes 2019-nCoV Tax:2697049
172 1190-1203 Species denotes coronaviruses Tax:11118
173 1267-1278 Species denotes coronavirus Tax:11118
174 1315-1334 Species denotes Rhinolophus affinis Tax:59477
175 1368-1377 Species denotes 2019-nCoV Tax:2697049
176 1426-1435 Species denotes 2019-nCoV Tax:2697049
177 1452-1471 Species denotes Rhinolophus affinis Tax:59477
178 1585-1590 Species denotes human Tax:9606
179 1757-1762 Species denotes β-CoV Tax:694002
180 1777-1790 Species denotes coronaviruses Tax:11118
181 1880-1889 Species denotes 2019-nCoV Tax:2697049
182 1996-2005 Species denotes 2019-nCoV Tax:2697049
183 588-607 Disease denotes respiratory disease MESH:D012140
184 770-790 Disease denotes respiratory diseases MESH:D012140
185 1138-1147 Disease denotes infection MESH:D007239
219 2073-2078 Gene denotes spike Gene:43740568
220 2573-2604 Gene denotes angiotensin-converting enzyme 2 Gene:59272
221 2606-2610 Gene denotes ACE2 Gene:59272
222 2679-2683 Gene denotes ACE2 Gene:59272
223 2785-2789 Gene denotes ACE2 Gene:100144303
224 2813-2817 Gene denotes ACE2 Gene:59272
225 2981-2985 Gene denotes ACE2 Gene:59272
226 3053-3057 Gene denotes ACE2 Gene:59272
227 3143-3147 Gene denotes ACE2 Gene:59272
228 3222-3229 Gene denotes TMPRSS2 Gene:7113
229 3306-3313 Gene denotes TMPRSS2 Gene:7113
230 2720-2723 Gene denotes bat Gene:570
231 2009-2018 Species denotes 2019-nCoV Tax:2697049
232 2041-2052 Species denotes coronavirus Tax:11118
233 2345-2356 Species denotes coronavirus Tax:11118
234 2512-2521 Species denotes 2019-nCoV Tax:2697049
235 2526-2534 Species denotes SARS-CoV Tax:694009
236 2536-2545 Species denotes 2019-nCoV Tax:2697049
237 2567-2572 Species denotes human Tax:9606
238 2640-2648 Species denotes SARS-CoV Tax:694009
239 2653-2662 Species denotes 2019-nCoV Tax:2697049
240 2713-2718 Species denotes human Tax:9606
241 2740-2743 Species denotes pig Tax:9823
242 2833-2841 Species denotes SARS-CoV Tax:694009
243 2930-2937 Species denotes patient Tax:9606
244 2960-2969 Species denotes 2019-nCoV Tax:2697049
245 3011-3020 Species denotes 2019-nCoV Tax:2697049
246 3062-3071 Species denotes 2019-nCoV Tax:2697049
247 3177-3186 Species denotes 2019-nCoV Tax:2697049
248 3275-3284 Species denotes 2019-nCoV Tax:2697049
249 2851-2856 Species denotes human Tax:9606
250 3206-3212 Chemical denotes serine MESH:D012694
251 2912-2929 Disease denotes SARS-CoV-infected MESH:C000657245

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T15 161-164 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T16 432-454 Body_part denotes central nervous system http://purl.org/sig/ont/fma/fma55675
T17 987-997 Body_part denotes nucleotide http://purl.org/sig/ont/fma/fma82740
T18 1221-1227 Body_part denotes genome http://purl.org/sig/ont/fma/fma84116
T19 1228-1238 Body_part denotes nucleotide http://purl.org/sig/ont/fma/fma82740
T20 1836-1842 Body_part denotes genome http://purl.org/sig/ont/fma/fma84116
T21 1899-1905 Body_part denotes genome http://purl.org/sig/ont/fma/fma84116
T22 2079-2086 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T23 2184-2192 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T24 2202-2205 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T25 2280-2292 Body_part denotes glycoprotein http://purl.org/sig/ont/fma/fma62925
T26 2332-2339 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T27 2469-2479 Body_part denotes amino acid http://purl.org/sig/ont/fma/fma82739
T28 2496-2503 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T29 2702-2707 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T30 2771-2776 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T31 2821-2829 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T32 2868-2876 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T33 2886-2891 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T34 3074-3081 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T35 3206-3212 Body_part denotes serine http://purl.org/sig/ont/fma/fma82764
T36 3256-3263 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T10 432-454 Body_part denotes central nervous system http://purl.obolibrary.org/obo/UBERON_0001017
T11 440-454 Body_part denotes nervous system http://purl.obolibrary.org/obo/UBERON_0001016
T12 2886-2891 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T30 313-323 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550
T31 588-607 Disease denotes respiratory disease http://purl.obolibrary.org/obo/MONDO_0005087
T32 628-636 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T33 628-632 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T34 801-809 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T35 801-805 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T36 1057-1065 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T37 1057-1061 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T38 1138-1147 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T39 2526-2534 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T40 2526-2530 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T41 2640-2648 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T42 2640-2644 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T43 2833-2841 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T44 2833-2837 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T45 2912-2920 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T46 2912-2916 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T27 336-341 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T28 346-357 http://purl.obolibrary.org/obo/NCBITaxon_7742 denotes vertebrates
T29 432-454 http://purl.obolibrary.org/obo/UBERON_0001017 denotes central nervous system
T30 432-454 http://www.ebi.ac.uk/efo/EFO_0000302 denotes central nervous system
T31 432-454 http://www.ebi.ac.uk/efo/EFO_0000908 denotes central nervous system
T32 458-464 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humans
T33 611-617 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humans
T34 793-795 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T35 1213-1215 http://purl.obolibrary.org/obo/CLO_0050509 denotes 27
T36 1265-1266 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T37 1311-1314 http://purl.obolibrary.org/obo/NCBITaxon_9397 denotes bat
T38 1577-1580 http://purl.obolibrary.org/obo/NCBITaxon_9397 denotes bat
T39 1585-1590 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T40 1592-1593 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T41 1653-1656 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T42 1834-1835 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T43 2095-2103 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T44 2175-2183 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T45 2567-2572 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T46 2702-2707 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T47 2713-2718 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T48 2720-2723 http://purl.obolibrary.org/obo/NCBITaxon_9397 denotes bat
T49 2771-2776 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T50 2795-2797 http://purl.obolibrary.org/obo/CLO_0001000 denotes 35
T51 2799-2800 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T52 2831-2832 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T53 2851-2856 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T54 2897-2898 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T55 3341-3342 http://purl.obolibrary.org/obo/CLO_0001020 denotes a

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T3 987-997 Chemical denotes nucleotide http://purl.obolibrary.org/obo/CHEBI_36976
T4 1228-1238 Chemical denotes nucleotide http://purl.obolibrary.org/obo/CHEBI_36976
T5 2079-2086 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T6 2184-2192 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T7 2280-2292 Chemical denotes glycoprotein http://purl.obolibrary.org/obo/CHEBI_17089
T8 2332-2339 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T9 2469-2479 Chemical denotes amino acid http://purl.obolibrary.org/obo/CHEBI_33709
T10 2469-2474 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T11 2475-2479 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T12 2496-2503 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T13 2573-2584 Chemical denotes angiotensin http://purl.obolibrary.org/obo/CHEBI_48433
T14 2731-2734 Chemical denotes cat http://purl.obolibrary.org/obo/CHEBI_32402
T15 3074-3081 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T16 3206-3212 Chemical denotes serine http://purl.obolibrary.org/obo/CHEBI_17822
T17 3256-3263 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T18 3314-3323 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T21 0-41 Sentence denotes Characteristics of 2019 novel coronavirus
T22 42-186 Sentence denotes Coronaviruses belong to the family of Coronaviridae, of the order Nidovirales, comprising large, single, plus-stranded RNA as their genome13,14.
T23 187-274 Sentence denotes Currently, there are four genera of coronaviruses: α-CoV, β-CoV, γ-CoV, and δ-CoV15,16.
T24 275-358 Sentence denotes Most of the coronavirus can cause the infectious diseases in human and vertebrates.
T25 359-532 Sentence denotes The α-CoV and β-CoV mainly infect the respiratory, gastrointestinal, and central nervous system of humans and mammals, while γ-CoV and δ-CoV mainly infect the birds13,17–19.
T26 533-796 Sentence denotes Usually, several members of the coronavirus cause mild respiratory disease in humans; however, SARS-CoV and the Middle East respiratory syndrome coronavirus (MERS-CoV) explored in 2002–2003 and in 2012, respectively, caused fatal severe respiratory diseases20–22.
T27 797-848 Sentence denotes The SARS-CoV and MERS-CoV belong to the β-CoV23,24.
T28 849-973 Sentence denotes 2019-nCoV explored in Wuhan also belongs to the β-CoV according to the phylogenetic analysis based on the viral genome10,11.
T29 974-1216 Sentence denotes Although the nucleotide sequence similarity is less than 80% between 2019-nCoV and SARS-CoV (about 79%) or MERS-CoV (about 50%), 2019-nCoV can also cause the fetal infection and spread more faster than the two other coronaviruses7,9,11,25–27.
T30 1217-1478 Sentence denotes The genome nucleotide sequence identity between a coronavirus (BatCoV RaTG13) detected in the bat Rhinolophus affinis from Yunnan Province, China, and 2019-nCoV, was 96.2%, indicating that the natural host of 2019-nCoV may also be the Rhinolophus affinis bat11.
T31 1479-1591 Sentence denotes However, the differences may also suggest that there is an or more intermediate hosts between the bat and human.
T32 1592-1765 Sentence denotes A research team from the South China Agricultural University has invested more than 1 000 metagenomic samples from pangolins, and found that 70% pangolins contained β-CoV28.
T33 1766-2008 Sentence denotes One of the coronaviruses they isolated from the pangolins comprised a genome that was very similar with that from 2019-nCoV, and the genome sequence similarity was 99%, indicating that the pangolin may be the intermediate host of 2019-nCoV29.
T34 2009-2325 Sentence denotes 2019-nCoV possessed the typical coronavirus structure with the “spike protein” in the membrane envelope30, and also expressed other polyproteins, nucleoproteins, and membrane proteins, such as RNA polymerase, 3-chymotrypsin-like protease, papain-like protease, helicase, glycoprotein, and accessory proteins10,11,30.
T35 2326-2444 Sentence denotes The S protein from coronavirus can bind to the receptors of the host to facilitate viral entry into target cells31,32.
T36 2445-2798 Sentence denotes Although there are four amino acid variations of S protein between 2019-nCoV and SARS-CoV, 2019-nCoV can also bind to the human angiotensin-converting enzyme 2 (ACE2), the same host receptor for SARS-CoV, as 2019-nCoV can bind to the ACE2 receptor from the cells from human, bat, civet cat, and pig, but it cannot bind to the cells without ACE211,33–35.
T37 2799-3026 Sentence denotes A recombinant ACE2-Ig antibody, a SARS-CoV-specific human monoclonal antibody, and the serum from a convalescent SARS-CoV-infected patient, which can neutralize 2019-nCoV, confirmed ACE2 as the host receptor for 2019-nCoV36–39.
T38 3027-3192 Sentence denotes The high affinity between ACE2 and 2019-nCoV S protein also suggested that the population with higher expression of ACE2 might be more susceptible to 2019-nCoV40,41.
T39 3193-3362 Sentence denotes The cellular serine protease TMPRSS2 also contributed to the S-protein priming of 2019-nCoV, indicating that the TMPRSS2 inhibitor might constitute a treatment option36.

2_test

Id Subject Object Predicate Lexical cue
32127517-25720466-53455628 180-182 25720466 denotes 13
32127517-16503362-53455629 183-185 16503362 denotes 14
32127517-25720466-53455630 523-525 25720466 denotes 13
32127517-19430490-53455631 526-528 19430490 denotes 17
32127517-22094080-53455631 526-528 22094080 denotes 17
32127517-29052924-53455631 526-528 29052924 denotes 17
32127517-12748314-53455632 790-792 12748314 denotes 20
32127517-12711460-53455632 790-792 12711460 denotes 20
32127517-25033169-53455633 842-844 25033169 denotes 23
32127517-32007143-53455634 1203-1204 32007143 denotes 7
32127517-27578435-53455635 2112-2114 27578435 denotes 30
32127517-27578435-53455636 2322-2324 27578435 denotes 30
32127517-30567993-53455637 2438-2440 30567993 denotes 31
32127517-22816037-53455638 2441-2443 22816037 denotes 32
32127517-32065055-53455639 3020-3022 32065055 denotes 36
T14354 180-182 25720466 denotes 13
T92968 183-185 16503362 denotes 14
T21125 523-525 25720466 denotes 13
T96006 526-528 19430490 denotes 17
T60685 526-528 22094080 denotes 17
T45452 526-528 29052924 denotes 17
T53573 790-792 12748314 denotes 20
T20710 790-792 12711460 denotes 20
T89661 842-844 25033169 denotes 23
T97420 1203-1204 32007143 denotes 7
T63019 2112-2114 27578435 denotes 30
T4951 2322-2324 27578435 denotes 30
T6721 2438-2440 30567993 denotes 31
T53119 2441-2443 22816037 denotes 32
T24045 3020-3022 32065055 denotes 36