PMC:7048180 / 6555-6769
Annnotations
{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7048180","sourcedb":"PMC","sourceid":"7048180","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7048180","text":"However, the arginine (R426 in SARS-CoV RBD) to asparagine (N439) mutation in 2019-nCoV RBD abolished the strong polar interactions, which may induce a decrease in the binding affinity between RBD and the receptor.","tracks":[{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T23","span":{"begin":13,"end":21},"obj":"Body_part"}],"attributes":[{"id":"A23","pred":"fma_id","subj":"T23","obj":"http://purl.org/sig/ont/fma/fma82763"},{"subj":"T23","pred":"source","obj":"LitCovid-PD-FMA-UBERON"}]},{"project":"LitCovid_AGAC","denotations":[{"id":"p8111s23","span":{"begin":92,"end":101},"obj":"NegReg"},{"id":"p8111s25","span":{"begin":106,"end":112},"obj":"MPA"},{"id":"p8111s26","span":{"begin":113,"end":131},"obj":"MPA"},{"id":"p8111s33","span":{"begin":152,"end":160},"obj":"NegReg"},{"id":"p8111s36","span":{"begin":168,"end":192},"obj":"Interaction"}],"attributes":[{"subj":"p8111s23","pred":"source","obj":"LitCovid_AGAC"},{"subj":"p8111s25","pred":"source","obj":"LitCovid_AGAC"},{"subj":"p8111s26","pred":"source","obj":"LitCovid_AGAC"},{"subj":"p8111s33","pred":"source","obj":"LitCovid_AGAC"},{"subj":"p8111s36","pred":"source","obj":"LitCovid_AGAC"}]},{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T39","span":{"begin":31,"end":39},"obj":"Disease"}],"attributes":[{"id":"A39","pred":"mondo_id","subj":"T39","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"subj":"T39","pred":"source","obj":"LitCovid-PD-MONDO"}]},{"project":"LitCovid-PD-CLO","denotations":[{"id":"T41","span":{"begin":150,"end":151},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"attributes":[{"subj":"T41","pred":"source","obj":"LitCovid-PD-CLO"}]},{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T34","span":{"begin":13,"end":21},"obj":"Chemical"},{"id":"T37","span":{"begin":48,"end":58},"obj":"Chemical"}],"attributes":[{"id":"A34","pred":"chebi_id","subj":"T34","obj":"http://purl.obolibrary.org/obo/CHEBI_16467"},{"id":"A35","pred":"chebi_id","subj":"T34","obj":"http://purl.obolibrary.org/obo/CHEBI_29016"},{"id":"A36","pred":"chebi_id","subj":"T34","obj":"http://purl.obolibrary.org/obo/CHEBI_32696"},{"id":"A37","pred":"chebi_id","subj":"T37","obj":"http://purl.obolibrary.org/obo/CHEBI_22653"},{"subj":"T34","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T37","pred":"source","obj":"LitCovid-PD-CHEBI"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T40","span":{"begin":0,"end":214},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T40","pred":"source","obj":"LitCovid-sentences"}]},{"project":"LitCovid-PubTator","denotations":[{"id":"251","span":{"begin":31,"end":39},"obj":"Species"},{"id":"252","span":{"begin":78,"end":87},"obj":"Species"},{"id":"270","span":{"begin":13,"end":21},"obj":"Chemical"},{"id":"271","span":{"begin":48,"end":58},"obj":"Chemical"}],"attributes":[{"id":"A251","pred":"tao:has_database_id","subj":"251","obj":"Tax:694009"},{"id":"A252","pred":"tao:has_database_id","subj":"252","obj":"Tax:2697049"},{"id":"A270","pred":"tao:has_database_id","subj":"270","obj":"MESH:D001120"},{"id":"A271","pred":"tao:has_database_id","subj":"271","obj":"MESH:D001216"},{"subj":"251","pred":"source","obj":"LitCovid-PubTator"},{"subj":"252","pred":"source","obj":"LitCovid-PubTator"},{"subj":"270","pred":"source","obj":"LitCovid-PubTator"},{"subj":"271","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PD-FMA-UBERON","color":"#ecd393","default":true},{"id":"LitCovid_AGAC","color":"#b993ec"},{"id":"LitCovid-PD-MONDO","color":"#93ec9f"},{"id":"LitCovid-PD-CLO","color":"#ec93a0"},{"id":"LitCovid-PD-CHEBI","color":"#93bbec"},{"id":"LitCovid-sentences","color":"#d5ec93"},{"id":"LitCovid-PubTator","color":"#e993ec"}]}]}}