PMC:7048180 / 4866-5942
Annnotations
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T18 | 55-67 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
T19 | 77-84 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T20 | 364-371 | Body_part | denotes | Protein | http://purl.org/sig/ont/fma/fma67257 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T31 | 302-310 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T32 | 408-416 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T33 | 500-508 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T34 | 578-586 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T35 | 595-603 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T36 | 685-693 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T33 | 11-12 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T34 | 159-165 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | tested |
T35 | 251-252 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | b |
T36 | 1008-1009 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T37 | 1010-1013 | http://purl.obolibrary.org/obo/CLO_0053733 | denotes | 1:1 |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T25 | 55-67 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
T26 | 77-84 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T27 | 151-155 | Chemical | denotes | MEGA | http://purl.obolibrary.org/obo/CHEBI_6617 |
T28 | 364-371 | Chemical | denotes | Protein | http://purl.obolibrary.org/obo/CHEBI_16541 |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T32 | 0-101 | Sentence | denotes | Figure 1. (a) Phylogenetic analysis of 2019-nCoV spike glycoprotein from its protein BLAST sequences. |
T33 | 102-970 | Sentence | denotes | The neighbour-joining tree was constructed using MEGA X, tested by bootstrap method of 2000 replicates, and edited by the online tool of iTOL (v5). (b) The simulated model of 2019-nCoV RBD binding to SARS-CoV-RBD-specific antibodies (m396, 80R, and F26G19). (c) Protein sequence alignment of 2019-nCoV and SARS-CoV RBD, showing the predominant residues that contribute to interactions with ACE2 or SARS-CoV-specific antibodies. (d) The comparison of the complex structures of SARS-CoV-RBD and SARS-CoV-RBD-specific antibodies (shown in the first row) and models of 2019-nCoV-RBD and SARS-CoV-RBD-specific antibodies (shown in the second row). (e) Binding of monoclonal antibodies to 2019-nCoV RBD determined by ELISA. (f) Binding profiles of 2019-nCoV RBD to ACE2 and antibodies, and (g) competition of CR3022 and ACE2 with 2019-nCoV RBD measured by BLI in OctetRED96. |
T34 | 971-1076 | Sentence | denotes | Binding kinetics was evaluated using a 1:1 Langmuir binding model by ForteBio Data Analysis 7.0 software. |
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
97 | 492-496 | Gene | denotes | ACE2 | Gene:59272 |
98 | 861-865 | Gene | denotes | ACE2 | Gene:59272 |
99 | 916-920 | Gene | denotes | ACE2 | Gene:59272 |
100 | 39-48 | Species | denotes | 2019-nCoV | Tax:2697049 |
101 | 277-286 | Species | denotes | 2019-nCoV | Tax:2697049 |
102 | 302-310 | Species | denotes | SARS-CoV | Tax:694009 |
103 | 394-403 | Species | denotes | 2019-nCoV | Tax:2697049 |
104 | 408-416 | Species | denotes | SARS-CoV | Tax:694009 |
105 | 578-586 | Species | denotes | SARS-CoV | Tax:694009 |
106 | 595-603 | Species | denotes | SARS-CoV | Tax:694009 |
107 | 667-676 | Species | denotes | 2019-nCoV | Tax:2697049 |
108 | 685-693 | Species | denotes | SARS-CoV | Tax:694009 |
109 | 785-794 | Species | denotes | 2019-nCoV | Tax:2697049 |
110 | 844-853 | Species | denotes | 2019-nCoV | Tax:2697049 |
111 | 926-935 | Species | denotes | 2019-nCoV | Tax:2697049 |
112 | 500-508 | Species | denotes | SARS-CoV | Tax:694009 |
113 | 905-911 | Chemical | denotes | CR3022 |