PMC:7047369 / 1098-2209
Annnotations
{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7047369","sourcedb":"PMC","sourceid":"7047369","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7047369","text":"The symptoms of COVID-19 are fever, dry cough, fatigue, nasal congestion, sore throat and diarrhoea. On February 14th, the Chinese Center for Disease Control and Prevention (China CDC) published the first details of 44,672 confirmed cases, in the biggest study since the outbreak began [3]. Their findings show that COVID-19 was mild for 81% of patients and had an overall case fatality rate of 2.3%. Of those confirmed cases, only 2.2% were under 20 years old. Compared to adults, children generally present with much milder clinical symptoms. It is likely that future serological studies will show much asymptomatic disease in children. As opposed to H1N1, pregnant women do not appear to be at higher risk of severe disease. The severity of the disease appears to be associated with age, with the elderly most at risk; those over 80 years of age had a Case Fatality Rate (CFR) of 14.8%. The CFR was also increased in those with comorbidities including cardiovascular, diabetes, chronic respiratory disease, hypertension, and cancer. The cause of death is respiratory failure, shock or multiple organ 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