PMC:7040011 / 130-1595
Annnotations
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T1 | 9-13 | Body_part | denotes | gene | http://purl.org/sig/ont/fma/fma74402 |
T2 | 501-508 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T3 | 613-620 | Body_part | denotes | tissues | http://purl.org/sig/ont/fma/fma9637 |
T4 | 736-740 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T5 | 741-744 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
T6 | 757-760 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
LitCovid_AGAC
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
p6832s6 | 459-465 | NegReg | denotes | reduce |
p6832s12 | 499-500 | Protein | denotes | S |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T2 | 113-129 | Disease | denotes | SARS-coronavirus | http://purl.obolibrary.org/obo/MONDO_0005091 |
T3 | 131-139 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T4 | 295-303 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T5 | 392-401 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T6 | 405-413 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T7 | 512-520 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T8 | 698-706 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T9 | 709-718 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T10 | 884-892 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T11 | 895-904 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T12 | 1402-1410 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 9-13 | http://purl.obolibrary.org/obo/OGG_0000000002 | denotes | gene |
T2 | 65-68 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
T3 | 149-154 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
T4 | 427-428 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T5 | 589-594 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
T6 | 720-721 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T7 | 736-740 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
T8 | 796-801 | http://purl.obolibrary.org/obo/UBERON_0003101 | denotes | males |
T9 | 796-801 | http://www.ebi.ac.uk/efo/EFO_0000970 | denotes | males |
T10 | 965-966 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T1 | 26-37 | Chemical | denotes | angiotensin | http://purl.obolibrary.org/obo/CHEBI_48433 |
T2 | 501-508 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T3 | 0-184 | Sentence | denotes | The ACE2 gene encodes the angiotensin-converting enzyme-2, which has been proved to be the receptor for both the SARS-coronavirus (SARS-CoV) and the human respiratory coronavirus NL63. |
T4 | 185-309 | Sentence | denotes | Recent studies and analyses indicate that ACE2 could be the host receptor for the novel coronavirus 2019-nCoV/SARS-CoV-21,2. |
T5 | 310-426 | Sentence | denotes | Previous studies demonstrated the positive correlation of ACE2 expression and the infection of SARS-CoV in vitro3,4. |
T6 | 427-530 | Sentence | denotes | A number of ACE2 variants could reduce the association between ACE2 and S-protein in SARS-CoV or NL635. |
T7 | 531-719 | Sentence | denotes | Therefore, the expression level and expression pattern of human ACE2 in different tissues might be critical for the susceptibility, symptoms, and outcome of 2019-nCoV/SARS-CoV-2 infection. |
T8 | 720-838 | Sentence | denotes | A recent single-cell RNA-sequencing (RNA-seq) analysis indicated that Asian males may have higher expression of ACE26. |
T9 | 839-964 | Sentence | denotes | Currently, the clinical reports of 2019-nCoV/SARS-CoV-2 infection from non-Asian populations for comparison are very limited. |
T10 | 965-1080 | Sentence | denotes | A study from Munich reported four German cases, all of which showed mild clinical symptoms without severe illness7. |
T11 | 1081-1190 | Sentence | denotes | However, the genetic basis of ACE2 expression and function in different populations is still largely unknown. |
T12 | 1191-1465 | Sentence | denotes | Therefore, genetic analysis of expression quantitative trait loci (eQTLs)8 and potential functional coding variants in ACE2 among populations are required for further epidemiological investigations of 2019-nCoV/SARS-CoV-2 spreading in East Asian (EAS) and other populations. |
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
43 | 685-687 | Gene | denotes | of | Gene:6688 |
44 | 1111-1115 | Gene | denotes | ACE2 | Gene:59272 |
45 | 832-836 | Gene | denotes | ACE2 | Gene:59272 |
46 | 595-599 | Gene | denotes | ACE2 | Gene:59272 |
47 | 490-494 | Gene | denotes | ACE2 | Gene:59272 |
48 | 439-443 | Gene | denotes | ACE2 | Gene:59272 |
49 | 368-372 | Gene | denotes | ACE2 | Gene:59272 |
50 | 227-231 | Gene | denotes | ACE2 | Gene:59272 |
51 | 1389-1391 | Gene | denotes | of | Gene:6688 |
52 | 1108-1110 | Gene | denotes | of | Gene:6688 |
53 | 1017-1019 | Gene | denotes | of | Gene:6688 |
54 | 871-873 | Gene | denotes | of | Gene:6688 |
55 | 829-831 | Gene | denotes | of | Gene:6688 |
56 | 436-438 | Gene | denotes | of | Gene:6688 |
57 | 402-404 | Gene | denotes | of | Gene:6688 |
58 | 365-367 | Gene | denotes | of | Gene:6688 |
59 | 113-129 | Species | denotes | SARS-coronavirus | Tax:694009 |
60 | 131-139 | Species | denotes | SARS-CoV | Tax:694009 |
61 | 149-154 | Species | denotes | human | Tax:9606 |
62 | 167-183 | Species | denotes | coronavirus NL63 | Tax:277944 |
63 | 267-284 | Species | denotes | novel coronavirus | Tax:2697049 |
64 | 285-294 | Species | denotes | 2019-nCoV | Tax:2697049 |
65 | 295-305 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
66 | 405-413 | Species | denotes | SARS-CoV | Tax:694009 |
67 | 512-520 | Species | denotes | SARS-CoV | Tax:694009 |
68 | 688-697 | Species | denotes | 2019-nCoV | Tax:2697049 |
69 | 874-883 | Species | denotes | 2019-nCoV | Tax:2697049 |
70 | 1392-1401 | Species | denotes | 2019-nCoV | Tax:2697049 |
71 | 1402-1412 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
72 | 524-528 | Species | denotes | NL63 | Tax:277944 |
73 | 392-401 | Disease | denotes | infection | MESH:D007239 |
74 | 703-718 | Disease | denotes | CoV-2 infection | MESH:C000657245 |
75 | 889-904 | Disease | denotes | CoV-2 infection | MESH:C000657245 |