PMC:7039956 / 6008-6865 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"175","span":{"begin":19,"end":23},"obj":"Gene"},{"id":"176","span":{"begin":80,"end":84},"obj":"Gene"},{"id":"177","span":{"begin":681,"end":685},"obj":"Gene"},{"id":"178","span":{"begin":329,"end":334},"obj":"Species"},{"id":"179","span":{"begin":549,"end":554},"obj":"Disease"}],"attributes":[{"id":"A175","pred":"tao:has_database_id","subj":"175","obj":"Gene:59272"},{"id":"A176","pred":"tao:has_database_id","subj":"176","obj":"Gene:59272"},{"id":"A177","pred":"tao:has_database_id","subj":"177","obj":"Gene:59272"},{"id":"A178","pred":"tao:has_database_id","subj":"178","obj":"Tax:10090"},{"id":"A179","pred":"tao:has_database_id","subj":"179","obj":"MESH:D009059"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"To investigate the ACE2 expression on mucosa of oral cavity, we looked into the ACE2 expression in different oral sites. According to the site information provided by the TCGA, among the 32 adjacent normal tissues, 13 tissues located in the oral tongue, 2 tissues located in the base of tongue, 3 tissues located in the floor of mouse, and 14 tissues did not definite the site and were just put into the category of oral cavity. The mean expression distribution of different sites was shown in Fig. 1c. When we combined the base of tongue, floor of mouth and oral cavity as other sites, and compared them with oral tongue, we found the obvious tendency that the mean expression of ACE2 was higher in oral tongue (13 tissues) than others (19 tissues) (Fig. 1d), while may due to the limitation of the sample size, the p value was not significant (P = 0.062)."}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T92","span":{"begin":38,"end":44},"obj":"Body_part"},{"id":"T93","span":{"begin":48,"end":59},"obj":"Body_part"},{"id":"T94","span":{"begin":206,"end":213},"obj":"Body_part"},{"id":"T95","span":{"begin":218,"end":225},"obj":"Body_part"},{"id":"T96","span":{"begin":246,"end":252},"obj":"Body_part"},{"id":"T97","span":{"begin":256,"end":263},"obj":"Body_part"},{"id":"T98","span":{"begin":279,"end":293},"obj":"Body_part"},{"id":"T99","span":{"begin":297,"end":304},"obj":"Body_part"},{"id":"T100","span":{"begin":343,"end":350},"obj":"Body_part"},{"id":"T101","span":{"begin":416,"end":427},"obj":"Body_part"},{"id":"T102","span":{"begin":524,"end":538},"obj":"Body_part"},{"id":"T103","span":{"begin":540,"end":554},"obj":"Body_part"},{"id":"T104","span":{"begin":559,"end":570},"obj":"Body_part"},{"id":"T105","span":{"begin":615,"end":621},"obj":"Body_part"},{"id":"T106","span":{"begin":705,"end":711},"obj":"Body_part"},{"id":"T107","span":{"begin":716,"end":723},"obj":"Body_part"},{"id":"T108","span":{"begin":741,"end":748},"obj":"Body_part"}],"attributes":[{"id":"A92","pred":"fma_id","subj":"T92","obj":"http://purl.org/sig/ont/fma/fma85355"},{"id":"A93","pred":"fma_id","subj":"T93","obj":"http://purl.org/sig/ont/fma/fma20292"},{"id":"A94","pred":"fma_id","subj":"T94","obj":"http://purl.org/sig/ont/fma/fma9637"},{"id":"A95","pred":"fma_id","subj":"T95","obj":"http://purl.org/sig/ont/fma/fma9637"},{"id":"A96","pred":"fma_id","subj":"T96","obj":"http://purl.org/sig/ont/fma/fma54640"},{"id":"A97","pred":"fma_id","subj":"T97","obj":"http://purl.org/sig/ont/fma/fma9637"},{"id":"A98","pred":"fma_id","subj":"T98","obj":"http://purl.org/sig/ont/fma/fma54645"},{"id":"A99","pred":"fma_id","subj":"T99","obj":"http://purl.org/sig/ont/fma/fma9637"},{"id":"A100","pred":"fma_id","subj":"T100","obj":"http://purl.org/sig/ont/fma/fma9637"},{"id":"A101","pred":"fma_id","subj":"T101","obj":"http://purl.org/sig/ont/fma/fma20292"},{"id":"A102","pred":"fma_id","subj":"T102","obj":"http://purl.org/sig/ont/fma/fma54645"},{"id":"A103","pred":"fma_id","subj":"T103","obj":"http://purl.org/sig/ont/fma/fma86592"},{"id":"A104","pred":"fma_id","subj":"T104","obj":"http://purl.org/sig/ont/fma/fma20292"},{"id":"A105","pred":"fma_id","subj":"T105","obj":"http://purl.org/sig/ont/fma/fma54640"},{"id":"A106","pred":"fma_id","subj":"T106","obj":"http://purl.org/sig/ont/fma/fma54640"},{"id":"A107","pred":"fma_id","subj":"T107","obj":"http://purl.org/sig/ont/fma/fma9637"},{"id":"A108","pred":"fma_id","subj":"T108","obj":"http://purl.org/sig/ont/fma/fma9637"}],"text":"To investigate the ACE2 expression on mucosa of oral cavity, we looked into the ACE2 expression in different oral sites. According to the site information provided by the TCGA, among the 32 adjacent normal tissues, 13 tissues located in the oral tongue, 2 tissues located in the base of tongue, 3 tissues located in the floor of mouse, and 14 tissues did not definite the site and were just put into the category of oral cavity. The mean expression distribution of different sites was shown in Fig. 1c. When we combined the base of tongue, floor of mouth and oral cavity as other sites, and compared them with oral tongue, we found the obvious tendency that the mean expression of ACE2 was higher in oral tongue (13 tissues) than others (19 tissues) (Fig. 1d), while may due to the limitation of the sample size, the p value was not significant (P = 0.062)."}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T47","span":{"begin":38,"end":44},"obj":"Body_part"},{"id":"T48","span":{"begin":48,"end":59},"obj":"Body_part"},{"id":"T49","span":{"begin":246,"end":252},"obj":"Body_part"},{"id":"T50","span":{"begin":287,"end":293},"obj":"Body_part"},{"id":"T51","span":{"begin":416,"end":427},"obj":"Body_part"},{"id":"T52","span":{"begin":532,"end":538},"obj":"Body_part"},{"id":"T53","span":{"begin":549,"end":554},"obj":"Body_part"},{"id":"T54","span":{"begin":559,"end":570},"obj":"Body_part"},{"id":"T55","span":{"begin":615,"end":621},"obj":"Body_part"},{"id":"T56","span":{"begin":705,"end":711},"obj":"Body_part"}],"attributes":[{"id":"A47","pred":"uberon_id","subj":"T47","obj":"http://purl.obolibrary.org/obo/UBERON_0000344"},{"id":"A48","pred":"uberon_id","subj":"T48","obj":"http://purl.obolibrary.org/obo/UBERON_0000167"},{"id":"A49","pred":"uberon_id","subj":"T49","obj":"http://purl.obolibrary.org/obo/UBERON_0001723"},{"id":"A50","pred":"uberon_id","subj":"T50","obj":"http://purl.obolibrary.org/obo/UBERON_0001723"},{"id":"A51","pred":"uberon_id","subj":"T51","obj":"http://purl.obolibrary.org/obo/UBERON_0000167"},{"id":"A52","pred":"uberon_id","subj":"T52","obj":"http://purl.obolibrary.org/obo/UBERON_0001723"},{"id":"A53","pred":"uberon_id","subj":"T53","obj":"http://purl.obolibrary.org/obo/UBERON_0000165"},{"id":"A54","pred":"uberon_id","subj":"T54","obj":"http://purl.obolibrary.org/obo/UBERON_0000167"},{"id":"A55","pred":"uberon_id","subj":"T55","obj":"http://purl.obolibrary.org/obo/UBERON_0001723"},{"id":"A56","pred":"uberon_id","subj":"T56","obj":"http://purl.obolibrary.org/obo/UBERON_0001723"}],"text":"To investigate the ACE2 expression on mucosa of oral cavity, we looked into the ACE2 expression in different oral sites. According to the site information provided by the TCGA, among the 32 adjacent normal tissues, 13 tissues located in the oral tongue, 2 tissues located in the base of tongue, 3 tissues located in the floor of mouse, and 14 tissues did not definite the site and were just put into the category of oral cavity. The mean expression distribution of different sites was shown in Fig. 1c. When we combined the base of tongue, floor of mouth and oral cavity as other sites, and compared them with oral tongue, we found the obvious tendency that the mean expression of ACE2 was higher in oral tongue (13 tissues) than others (19 tissues) (Fig. 1d), while may due to the limitation of the sample size, the p value was not significant (P = 0.062)."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T108","span":{"begin":38,"end":44},"obj":"http://purl.obolibrary.org/obo/UBERON_0000344"},{"id":"T109","span":{"begin":48,"end":59},"obj":"http://purl.obolibrary.org/obo/UBERON_0000167"},{"id":"T110","span":{"begin":48,"end":59},"obj":"http://www.ebi.ac.uk/efo/EFO_0000825"},{"id":"T111","span":{"begin":246,"end":252},"obj":"http://purl.obolibrary.org/obo/UBERON_0001723"},{"id":"T112","span":{"begin":287,"end":293},"obj":"http://purl.obolibrary.org/obo/UBERON_0001723"},{"id":"T113","span":{"begin":329,"end":334},"obj":"http://purl.obolibrary.org/obo/CLO_0007836"},{"id":"T114","span":{"begin":416,"end":427},"obj":"http://purl.obolibrary.org/obo/UBERON_0000167"},{"id":"T115","span":{"begin":416,"end":427},"obj":"http://www.ebi.ac.uk/efo/EFO_0000825"},{"id":"T116","span":{"begin":532,"end":538},"obj":"http://purl.obolibrary.org/obo/UBERON_0001723"},{"id":"T117","span":{"begin":549,"end":554},"obj":"http://www.ebi.ac.uk/efo/EFO_0000825"},{"id":"T118","span":{"begin":559,"end":570},"obj":"http://purl.obolibrary.org/obo/UBERON_0000167"},{"id":"T119","span":{"begin":559,"end":570},"obj":"http://www.ebi.ac.uk/efo/EFO_0000825"},{"id":"T120","span":{"begin":615,"end":621},"obj":"http://purl.obolibrary.org/obo/UBERON_0001723"},{"id":"T121","span":{"begin":705,"end":711},"obj":"http://purl.obolibrary.org/obo/UBERON_0001723"}],"text":"To investigate the ACE2 expression on mucosa of oral cavity, we looked into the ACE2 expression in different oral sites. According to the site information provided by the TCGA, among the 32 adjacent normal tissues, 13 tissues located in the oral tongue, 2 tissues located in the base of tongue, 3 tissues located in the floor of mouse, and 14 tissues did not definite the site and were just put into the category of oral cavity. The mean expression distribution of different sites was shown in Fig. 1c. When we combined the base of tongue, floor of mouth and oral cavity as other sites, and compared them with oral tongue, we found the obvious tendency that the mean expression of ACE2 was higher in oral tongue (13 tissues) than others (19 tissues) (Fig. 1d), while may due to the limitation of the sample size, the p value was not significant (P = 0.062)."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T11","span":{"begin":279,"end":283},"obj":"Chemical"},{"id":"T12","span":{"begin":524,"end":528},"obj":"Chemical"}],"attributes":[{"id":"A11","pred":"chebi_id","subj":"T11","obj":"http://purl.obolibrary.org/obo/CHEBI_22695"},{"id":"A12","pred":"chebi_id","subj":"T12","obj":"http://purl.obolibrary.org/obo/CHEBI_22695"}],"text":"To investigate the ACE2 expression on mucosa of oral cavity, we looked into the ACE2 expression in different oral sites. According to the site information provided by the TCGA, among the 32 adjacent normal tissues, 13 tissues located in the oral tongue, 2 tissues located in the base of tongue, 3 tissues located in the floor of mouse, and 14 tissues did not definite the site and were just put into the category of oral cavity. The mean expression distribution of different sites was shown in Fig. 1c. When we combined the base of tongue, floor of mouth and oral cavity as other sites, and compared them with oral tongue, we found the obvious tendency that the mean expression of ACE2 was higher in oral tongue (13 tissues) than others (19 tissues) (Fig. 1d), while may due to the limitation of the sample size, the p value was not significant (P = 0.062)."}

{"project":"LitCovid-sentences","denotations":[{"id":"T49","span":{"begin":0,"end":120},"obj":"Sentence"},{"id":"T50","span":{"begin":121,"end":428},"obj":"Sentence"},{"id":"T51","span":{"begin":429,"end":502},"obj":"Sentence"},{"id":"T52","span":{"begin":503,"end":857},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"To investigate the ACE2 expression on mucosa of oral cavity, we looked into the ACE2 expression in different oral sites. According to the site information provided by the TCGA, among the 32 adjacent normal tissues, 13 tissues located in the oral tongue, 2 tissues located in the base of tongue, 3 tissues located in the floor of mouse, and 14 tissues did not definite the site and were just put into the category of oral cavity. The mean expression distribution of different sites was shown in Fig. 1c. When we combined the base of tongue, floor of mouth and oral cavity as other sites, and compared them with oral tongue, we found the obvious tendency that the mean expression of ACE2 was higher in oral tongue (13 tissues) than others (19 tissues) (Fig. 1d), while may due to the limitation of the sample size, the p value was not significant (P = 0.062)."}