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PMC:7039956 / 4613-8928 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
147 573-577 Gene denotes ACE2 Gene:59272
148 666-670 Gene denotes ACE2 Gene:59272
149 760-764 Gene denotes ACE2 Gene:59272
150 880-884 Gene denotes ACE2 Gene:59272
151 713-717 Gene denotes CAGE Gene:168400
152 592-606 Disease denotes para-carcinoma MESH:D002277
153 779-793 Disease denotes para-carcinoma MESH:D002277
155 1050-1054 Gene denotes ACE2 Gene:59272
158 969-973 Gene denotes ACE2 Gene:59272
159 988-1002 Disease denotes para-carcinoma MESH:D002277
165 207-211 Gene denotes ACE2 Gene:59272
166 353-357 Gene denotes ACE2 Gene:59272
167 399-403 Gene denotes ACE2 Gene:59272
168 483-487 Gene denotes CAGE Gene:168400
169 93-107 Disease denotes para-carcinoma MESH:D002277
175 1414-1418 Gene denotes ACE2 Gene:59272
176 1475-1479 Gene denotes ACE2 Gene:59272
177 2076-2080 Gene denotes ACE2 Gene:59272
178 1724-1729 Species denotes mouse Tax:10090
179 1944-1949 Disease denotes mouth MESH:D009059
185 3423-3427 Gene denotes ACE2 Gene:59272
186 3457-3461 Gene denotes ACE2 Gene:59272
187 3519-3523 Gene denotes ACE2 Gene:59272
188 3612-3616 Gene denotes ACE2 Gene:59272
189 3504-3510 Gene denotes Violin
217 2458-2462 Gene denotes ACE2 Gene:59272
218 2659-2662 Gene denotes SFN Gene:104444
219 2664-2669 Gene denotes KRT6A Gene:16687
220 2675-2680 Gene denotes KRT10 Gene:16661
221 2719-2722 Gene denotes FAP Gene:14089
222 2724-2728 Gene denotes PDPN Gene:14726
223 2730-2736 Gene denotes COL1A2 Gene:12843
224 2738-2741 Gene denotes DCN Gene:13179
225 2743-2749 Gene denotes COL3A1 Gene:1281
226 2751-2757 Gene denotes COL6A1 Gene:1291
227 2792-2795 Gene denotes CD2 Gene:914
228 2797-2801 Gene denotes CD3D Gene:915
229 2803-2807 Gene denotes CD3E Gene:916
230 2813-2817 Gene denotes CD3G Gene:917
231 2856-2861 Gene denotes CD163 Gene:9332
232 2863-2868 Gene denotes CSF1R Gene:1436
233 2880-2886 Gene denotes FCGR2A Gene:2212
234 2924-2928 Gene denotes CMA1 Gene:1215
235 2930-2935 Gene denotes MS4A2 Gene:2206
236 2937-2943 Gene denotes TPSAB1 Gene:100503895
237 2945-2950 Gene denotes TPSB2 Gene:17229
238 2985-2991 Gene denotes SLAMF7 Gene:75345
239 2993-2998 Gene denotes FCRL5 Gene:329693
240 3004-3009 Gene denotes CD79A Gene:12518
241 3057-3063 Gene denotes PECAM1 Gene:18613
242 3065-3068 Gene denotes VWF Gene:22371
243 3074-3077 Gene denotes ENG Gene:13805
252 3670-3674 Gene denotes ACE2 Gene:59272
253 3712-3716 Gene denotes ACE2 Gene:59272
254 3801-3805 Gene denotes ACE2 Gene:59272
255 3871-3875 Gene denotes ACE2 Gene:59272
256 3956-3960 Gene denotes ACE2 Gene:59272
257 4044-4048 Gene denotes ACE2 Gene:59272
258 4106-4110 Gene denotes ACE2 Gene:59272
259 4201-4205 Gene denotes ACE2 Gene:59272

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T68 21-24 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T69 115-122 Body_part denotes tissues http://purl.org/sig/ont/fma/fma9637
T70 363-369 Body_part denotes mucosa http://purl.org/sig/ont/fma/fma85355
T71 373-384 Body_part denotes oral cavity http://purl.org/sig/ont/fma/fma20292
T72 458-465 Body_part denotes tissues http://purl.org/sig/ont/fma/fma9637
T73 519-522 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T74 614-621 Body_part denotes tissues http://purl.org/sig/ont/fma/fma9637
T75 692-699 Body_part denotes tissues http://purl.org/sig/ont/fma/fma9637
T76 801-808 Body_part denotes tissues http://purl.org/sig/ont/fma/fma9637
T77 1010-1017 Body_part denotes tissues http://purl.org/sig/ont/fma/fma9637
T78 1104-1113 Body_part denotes Intestine http://purl.org/sig/ont/fma/fma7199
T79 1128-1134 Body_part denotes Kidney http://purl.org/sig/ont/fma/fma7203
T80 1150-1157 Body_part denotes Stomach http://purl.org/sig/ont/fma/fma7148
T81 1172-1181 Body_part denotes Bile duct http://purl.org/sig/ont/fma/fma9706
T82 1172-1176 Body_part denotes Bile http://purl.org/sig/ont/fma/fma62971
T83 1195-1200 Body_part denotes Liver http://purl.org/sig/ont/fma/fma7197
T84 1215-1226 Body_part denotes Oral cavity http://purl.org/sig/ont/fma/fma20292
T85 1241-1245 Body_part denotes Lung http://purl.org/sig/ont/fma/fma7195
T86 1261-1268 Body_part denotes Thyroid http://purl.org/sig/ont/fma/fma9603
T87 1283-1292 Body_part denotes Esophagus http://purl.org/sig/ont/fma/fma7131
T88 1307-1314 Body_part denotes Bladder http://purl.org/sig/ont/fma/fma15900
T89 1329-1335 Body_part denotes Breast http://purl.org/sig/ont/fma/fma9601
T90 1351-1357 Body_part denotes Uterus http://purl.org/sig/ont/fma/fma17558
T91 1372-1380 Body_part denotes Prostate http://purl.org/sig/ont/fma/fma9600
T92 1433-1439 Body_part denotes mucosa http://purl.org/sig/ont/fma/fma85355
T93 1443-1454 Body_part denotes oral cavity http://purl.org/sig/ont/fma/fma20292
T94 1601-1608 Body_part denotes tissues http://purl.org/sig/ont/fma/fma9637
T95 1613-1620 Body_part denotes tissues http://purl.org/sig/ont/fma/fma9637
T96 1641-1647 Body_part denotes tongue http://purl.org/sig/ont/fma/fma54640
T97 1651-1658 Body_part denotes tissues http://purl.org/sig/ont/fma/fma9637
T98 1674-1688 Body_part denotes base of tongue http://purl.org/sig/ont/fma/fma54645
T99 1692-1699 Body_part denotes tissues http://purl.org/sig/ont/fma/fma9637
T100 1738-1745 Body_part denotes tissues http://purl.org/sig/ont/fma/fma9637
T101 1811-1822 Body_part denotes oral cavity http://purl.org/sig/ont/fma/fma20292
T102 1919-1933 Body_part denotes base of tongue http://purl.org/sig/ont/fma/fma54645
T103 1935-1949 Body_part denotes floor of mouth http://purl.org/sig/ont/fma/fma86592
T104 1954-1965 Body_part denotes oral cavity http://purl.org/sig/ont/fma/fma20292
T105 2010-2016 Body_part denotes tongue http://purl.org/sig/ont/fma/fma54640
T106 2100-2106 Body_part denotes tongue http://purl.org/sig/ont/fma/fma54640
T107 2111-2118 Body_part denotes tissues http://purl.org/sig/ont/fma/fma9637
T108 2136-2143 Body_part denotes tissues http://purl.org/sig/ont/fma/fma9637
T109 2261-2265 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T110 2266-2269 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T111 2291-2298 Body_part denotes tissues http://purl.org/sig/ont/fma/fma9637
T112 2306-2310 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T113 2311-2314 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T114 2346-2353 Body_part denotes tissues http://purl.org/sig/ont/fma/fma9637
T115 2425-2429 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T116 2544-2549 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T117 2570-2574 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T118 2618-2634 Body_part denotes epithelial cells http://purl.org/sig/ont/fma/fma66768
T119 2629-2634 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T120 2683-2694 Body_part denotes fibroblasts http://purl.org/sig/ont/fma/fma63877
T121 2762-2767 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T122 2820-2831 Body_part denotes macrophages http://purl.org/sig/ont/fma/fma63261
T123 2889-2899 Body_part denotes mast cells http://purl.org/sig/ont/fma/fma66784
T124 2894-2899 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T125 2955-2960 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T126 3015-3032 Body_part denotes endothelial cells http://purl.org/sig/ont/fma/fma66772
T127 3027-3032 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T128 3100-3104 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T129 3124-3128 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T130 3174-3178 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T131 3179-3182 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T132 3204-3211 Body_part denotes tissues http://purl.org/sig/ont/fma/fma9637
T133 3246-3250 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T134 3280-3284 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T135 3294-3299 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T136 3344-3348 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T137 3373-3377 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T138 3412-3417 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T139 3552-3556 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T140 3583-3589 Body_part denotes tongue http://purl.org/sig/ont/fma/fma54640
T141 3590-3606 Body_part denotes epithelial cells http://purl.org/sig/ont/fma/fma66768
T142 3601-3606 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T143 3697-3704 Body_part denotes tissues http://purl.org/sig/ont/fma/fma9637
T144 3726-3731 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T145 3753-3759 Body_part denotes tongue http://purl.org/sig/ont/fma/fma54640
T146 3785-3792 Body_part denotes tissues http://purl.org/sig/ont/fma/fma9637
T147 3815-3820 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T148 3837-3843 Body_part denotes tongue http://purl.org/sig/ont/fma/fma54640
T149 3885-3890 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T150 3914-3921 Body_part denotes tissues http://purl.org/sig/ont/fma/fma9637
T151 3932-3948 Body_part denotes epithelial cells http://purl.org/sig/ont/fma/fma66768
T152 3943-3948 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T153 3970-3975 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T154 3980-3985 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T155 3997-4002 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T156 4016-4026 Body_part denotes fibroblast http://purl.org/sig/ont/fma/fma63877
T157 4072-4088 Body_part denotes epithelial cells http://purl.org/sig/ont/fma/fma66768
T158 4083-4088 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T159 4120-4125 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T160 4136-4152 Body_part denotes epithelial cells http://purl.org/sig/ont/fma/fma66768
T161 4147-4152 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T162 4232-4248 Body_part denotes epithelial cells http://purl.org/sig/ont/fma/fma66768
T163 4243-4248 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T164 4256-4267 Body_part denotes oral mucosa http://purl.org/sig/ont/fma/fma59660
T165 4261-4267 Body_part denotes mucosa http://purl.org/sig/ont/fma/fma85355
T166 4291-4297 Body_part denotes tongue http://purl.org/sig/ont/fma/fma54640
T167 4298-4314 Body_part denotes epithelial cells http://purl.org/sig/ont/fma/fma66768
T168 4309-4314 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T26 72-78 Body_part denotes organs http://purl.obolibrary.org/obo/UBERON_0000062
T27 242-248 Body_part denotes organs http://purl.obolibrary.org/obo/UBERON_0000062
T28 283-289 Body_part denotes organs http://purl.obolibrary.org/obo/UBERON_0000062
T29 363-369 Body_part denotes mucosa http://purl.obolibrary.org/obo/UBERON_0000344
T30 373-384 Body_part denotes oral cavity http://purl.obolibrary.org/obo/UBERON_0000167
T31 644-650 Body_part denotes organs http://purl.obolibrary.org/obo/UBERON_0000062
T32 738-744 Body_part denotes organs http://purl.obolibrary.org/obo/UBERON_0000062
T33 1031-1037 Body_part denotes organs http://purl.obolibrary.org/obo/UBERON_0000062
T34 1104-1113 Body_part denotes Intestine http://purl.obolibrary.org/obo/UBERON_0000160
T35 1128-1134 Body_part denotes Kidney http://purl.obolibrary.org/obo/UBERON_0002113
T36 1150-1157 Body_part denotes Stomach http://purl.obolibrary.org/obo/UBERON_0000945
T37 1172-1181 Body_part denotes Bile duct http://purl.obolibrary.org/obo/UBERON_0002394
T38 1177-1181 Body_part denotes duct http://purl.obolibrary.org/obo/UBERON_0000058
T39 1195-1200 Body_part denotes Liver http://purl.obolibrary.org/obo/UBERON_0002107
T40 1215-1226 Body_part denotes Oral cavity http://purl.obolibrary.org/obo/UBERON_0000167
T41 1241-1245 Body_part denotes Lung http://purl.obolibrary.org/obo/UBERON_0002048
T42 1261-1268 Body_part denotes Thyroid http://purl.obolibrary.org/obo/UBERON_0002046
T43 1283-1292 Body_part denotes Esophagus http://purl.obolibrary.org/obo/UBERON_0001043
T44 1307-1314 Body_part denotes Bladder http://purl.obolibrary.org/obo/UBERON_0001255
T45 1329-1335 Body_part denotes Breast http://purl.obolibrary.org/obo/UBERON_0000310
T46 1351-1357 Body_part denotes Uterus http://purl.obolibrary.org/obo/UBERON_0000995
T47 1433-1439 Body_part denotes mucosa http://purl.obolibrary.org/obo/UBERON_0000344
T48 1443-1454 Body_part denotes oral cavity http://purl.obolibrary.org/obo/UBERON_0000167
T49 1641-1647 Body_part denotes tongue http://purl.obolibrary.org/obo/UBERON_0001723
T50 1682-1688 Body_part denotes tongue http://purl.obolibrary.org/obo/UBERON_0001723
T51 1811-1822 Body_part denotes oral cavity http://purl.obolibrary.org/obo/UBERON_0000167
T52 1927-1933 Body_part denotes tongue http://purl.obolibrary.org/obo/UBERON_0001723
T53 1944-1949 Body_part denotes mouth http://purl.obolibrary.org/obo/UBERON_0000165
T54 1954-1965 Body_part denotes oral cavity http://purl.obolibrary.org/obo/UBERON_0000167
T55 2010-2016 Body_part denotes tongue http://purl.obolibrary.org/obo/UBERON_0001723
T56 2100-2106 Body_part denotes tongue http://purl.obolibrary.org/obo/UBERON_0001723
T57 3583-3589 Body_part denotes tongue http://purl.obolibrary.org/obo/UBERON_0001723
T58 3753-3759 Body_part denotes tongue http://purl.obolibrary.org/obo/UBERON_0001723
T59 3837-3843 Body_part denotes tongue http://purl.obolibrary.org/obo/UBERON_0001723
T60 4261-4267 Body_part denotes mucosa http://purl.obolibrary.org/obo/UBERON_0000344
T61 4291-4297 Body_part denotes tongue http://purl.obolibrary.org/obo/UBERON_0001723

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T15 98-107 Phenotype denotes carcinoma http://purl.obolibrary.org/obo/HP_0030731
T16 597-606 Phenotype denotes carcinoma http://purl.obolibrary.org/obo/HP_0030731
T17 784-793 Phenotype denotes carcinoma http://purl.obolibrary.org/obo/HP_0030731
T18 993-1002 Phenotype denotes carcinoma http://purl.obolibrary.org/obo/HP_0030731

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T24 98-107 Disease denotes carcinoma http://purl.obolibrary.org/obo/MONDO_0004993
T25 597-606 Disease denotes carcinoma http://purl.obolibrary.org/obo/MONDO_0004993
T26 784-793 Disease denotes carcinoma http://purl.obolibrary.org/obo/MONDO_0004993
T27 993-1002 Disease denotes carcinoma http://purl.obolibrary.org/obo/MONDO_0004993
T28 2719-2722 Disease denotes FAP http://purl.obolibrary.org/obo/MONDO_0021055
T29 2797-2801 Disease denotes CD3D http://purl.obolibrary.org/obo/MONDO_0014280

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T78 72-78 http://purl.obolibrary.org/obo/UBERON_0003103 denotes organs
T79 242-248 http://purl.obolibrary.org/obo/UBERON_0003103 denotes organs
T80 283-289 http://purl.obolibrary.org/obo/UBERON_0003103 denotes organs
T81 363-369 http://purl.obolibrary.org/obo/UBERON_0000344 denotes mucosa
T82 373-384 http://purl.obolibrary.org/obo/UBERON_0000167 denotes oral cavity
T83 373-384 http://www.ebi.ac.uk/efo/EFO_0000825 denotes oral cavity
T84 556-557 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T85 644-650 http://purl.obolibrary.org/obo/UBERON_0003103 denotes organs
T86 652-653 http://purl.obolibrary.org/obo/CLO_0001021 denotes b
T87 738-744 http://purl.obolibrary.org/obo/UBERON_0003103 denotes organs
T88 1031-1037 http://purl.obolibrary.org/obo/UBERON_0003103 denotes organs
T89 1104-1113 http://purl.obolibrary.org/obo/UBERON_0000160 denotes Intestine
T90 1104-1113 http://www.ebi.ac.uk/efo/EFO_0000834 denotes Intestine
T91 1128-1134 http://purl.obolibrary.org/obo/UBERON_0002113 denotes Kidney
T92 1128-1134 http://www.ebi.ac.uk/efo/EFO_0000927 denotes Kidney
T93 1128-1134 http://www.ebi.ac.uk/efo/EFO_0000929 denotes Kidney
T94 1158-1160 http://purl.obolibrary.org/obo/CLO_0001000 denotes 35
T95 1172-1181 http://purl.obolibrary.org/obo/UBERON_0002394 denotes Bile duct
T96 1195-1200 http://purl.obolibrary.org/obo/UBERON_0002107 denotes Liver
T97 1195-1200 http://www.ebi.ac.uk/efo/EFO_0000887 denotes Liver
T98 1215-1226 http://purl.obolibrary.org/obo/UBERON_0000167 denotes Oral cavity
T99 1215-1226 http://www.ebi.ac.uk/efo/EFO_0000825 denotes Oral cavity
T100 1241-1245 http://purl.obolibrary.org/obo/UBERON_0002048 denotes Lung
T101 1241-1245 http://www.ebi.ac.uk/efo/EFO_0000934 denotes Lung
T102 1283-1292 http://purl.obolibrary.org/obo/UBERON_0001043 denotes Esophagus
T103 1293-1295 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T104 1329-1335 http://purl.obolibrary.org/obo/UBERON_0000310 denotes Breast
T105 1351-1357 http://purl.obolibrary.org/obo/UBERON_0000995 denotes Uterus
T106 1351-1357 http://www.ebi.ac.uk/efo/EFO_0000975 denotes Uterus
T107 1381-1383 http://purl.obolibrary.org/obo/CLO_0001407 denotes 52
T108 1433-1439 http://purl.obolibrary.org/obo/UBERON_0000344 denotes mucosa
T109 1443-1454 http://purl.obolibrary.org/obo/UBERON_0000167 denotes oral cavity
T110 1443-1454 http://www.ebi.ac.uk/efo/EFO_0000825 denotes oral cavity
T111 1641-1647 http://purl.obolibrary.org/obo/UBERON_0001723 denotes tongue
T112 1682-1688 http://purl.obolibrary.org/obo/UBERON_0001723 denotes tongue
T113 1724-1729 http://purl.obolibrary.org/obo/CLO_0007836 denotes mouse
T114 1811-1822 http://purl.obolibrary.org/obo/UBERON_0000167 denotes oral cavity
T115 1811-1822 http://www.ebi.ac.uk/efo/EFO_0000825 denotes oral cavity
T116 1927-1933 http://purl.obolibrary.org/obo/UBERON_0001723 denotes tongue
T117 1944-1949 http://www.ebi.ac.uk/efo/EFO_0000825 denotes mouth
T118 1954-1965 http://purl.obolibrary.org/obo/UBERON_0000167 denotes oral cavity
T119 1954-1965 http://www.ebi.ac.uk/efo/EFO_0000825 denotes oral cavity
T120 2010-2016 http://purl.obolibrary.org/obo/UBERON_0001723 denotes tongue
T121 2100-2106 http://purl.obolibrary.org/obo/UBERON_0001723 denotes tongue
T122 2261-2265 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T123 2306-2310 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T124 2425-2434 http://purl.obolibrary.org/obo/CL_0000000 denotes cell type
T125 2537-2539 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T126 2544-2549 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T127 2570-2580 http://purl.obolibrary.org/obo/CL_0000000 denotes cell types
T128 2603-2605 http://purl.obolibrary.org/obo/CLO_0001236 denotes 2a
T129 2618-2628 http://purl.obolibrary.org/obo/CL_0000066 denotes epithelial
T130 2629-2634 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T131 2643-2648 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T132 2683-2694 http://purl.obolibrary.org/obo/CL_0000057 denotes fibroblasts
T133 2703-2708 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T134 2760-2767 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T135 2776-2781 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T136 2840-2845 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T137 2863-2868 http://purl.obolibrary.org/obo/PR_000002062 denotes CSF1R
T138 2870-2874 http://purl.obolibrary.org/obo/PR_000002064 denotes CD68
T139 2894-2899 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T140 2908-2913 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T141 2953-2960 http://purl.obolibrary.org/obo/CL_0000236 denotes B cells
T142 2969-2974 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T143 3015-3032 http://purl.obolibrary.org/obo/CL_0000115 denotes endothelial cells
T144 3041-3046 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T145 3100-3104 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T146 3124-3134 http://purl.obolibrary.org/obo/CL_0000000 denotes cell types
T147 3174-3178 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T148 3238-3239 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T149 3246-3256 http://purl.obolibrary.org/obo/CL_0000000 denotes cell types
T150 3280-3284 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T151 3294-3299 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T152 3331-3332 http://purl.obolibrary.org/obo/CLO_0001021 denotes b
T153 3344-3348 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T154 3373-3383 http://purl.obolibrary.org/obo/CL_0000000 denotes cell types
T155 3412-3417 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T156 3552-3562 http://purl.obolibrary.org/obo/CL_0000000 denotes cell types
T157 3583-3589 http://purl.obolibrary.org/obo/UBERON_0001723 denotes tongue
T158 3590-3600 http://purl.obolibrary.org/obo/CL_0000066 denotes epithelial
T159 3601-3606 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T160 3726-3731 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T161 3753-3759 http://purl.obolibrary.org/obo/UBERON_0001723 denotes tongue
T162 3815-3820 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T163 3837-3843 http://purl.obolibrary.org/obo/UBERON_0001723 denotes tongue
T164 3885-3890 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T165 3932-3942 http://purl.obolibrary.org/obo/CL_0000066 denotes epithelial
T166 3943-3948 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T167 3970-3975 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T168 3978-3985 http://purl.obolibrary.org/obo/CL_0000084 denotes T cells
T169 3995-4002 http://purl.obolibrary.org/obo/CL_0000236 denotes B cells
T170 4016-4026 http://purl.obolibrary.org/obo/CL_0000057 denotes fibroblast
T171 4072-4082 http://purl.obolibrary.org/obo/CL_0000066 denotes epithelial
T172 4083-4088 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T173 4120-4125 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T174 4136-4146 http://purl.obolibrary.org/obo/CL_0000066 denotes epithelial
T175 4147-4152 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T176 4232-4242 http://purl.obolibrary.org/obo/CL_0000066 denotes epithelial
T177 4243-4248 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T178 4261-4267 http://purl.obolibrary.org/obo/UBERON_0000344 denotes mucosa
T179 4291-4297 http://purl.obolibrary.org/obo/UBERON_0001723 denotes tongue
T180 4298-4308 http://purl.obolibrary.org/obo/CL_0000066 denotes epithelial
T181 4309-4314 http://purl.obolibrary.org/obo/GO_0005623 denotes cells

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T9 46-48 Chemical denotes NA http://purl.obolibrary.org/obo/CHEBI_33696
T10 1261-1268 Chemical denotes Thyroid http://purl.obolibrary.org/obo/CHEBI_9584
T11 1674-1678 Chemical denotes base http://purl.obolibrary.org/obo/CHEBI_22695
T12 1919-1923 Chemical denotes base http://purl.obolibrary.org/obo/CHEBI_22695
T13 2719-2722 Chemical denotes FAP http://purl.obolibrary.org/obo/CHEBI_73617

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T29 0-7 Sentence denotes Results
T30 9-45 Sentence denotes Public bulk RNA-seq dataset analysis
T31 46-316 Sentence denotes NA-seq profile data of 13 organs including 695 para-carcinoma normal tissues as control from public TCGA were obtained for our analysis, and Fig. 1a showed that ACE2 could be expressed in various organs, the mean expression of different organs could be found in Table 1.
T32 317-506 Sentence denotes According to the mean expression of ACE2, the mucosa of oral cavity could express ACE2, and the results were validated by the data of normal tissues from the FANTOM5 CAGE dataset (Fig. 1b).
T33 507-944 Sentence denotes Fig. 1 Bulk RNA-seq analysis of public datasets. a Violin plot of ACE2 expression in para-carcinoma normal tissues from TCGA, colored by organs. b Bar plot of ACE2 expression in normal tissues from FANTOM5 CAGE dataset, colored by organs. c Bar plot of ACE2 expression of para-carcinoma normal tissues from TCGA in different oral sites, colored by oral sites; d Boxplot of ACE2 in two kinds of oral sites from TCGA, colored by oral sites
T34 945-1037 Sentence denotes Table 1 Sample size and ACE2 expression of para-carcinoma normal tissues in different organs
T35 1038-1103 Sentence denotes Sample size ACE2 mean expression Standard deviation of expression
T36 1104-1127 Sentence denotes Intestine 51 9.50 1.183
T37 1128-1149 Sentence denotes Kidney 129 9.20 2.410
T38 1150-1171 Sentence denotes Stomach 35 8.25 3.715
T39 1172-1194 Sentence denotes Bile duct 9 7.23 1.163
T40 1195-1214 Sentence denotes Liver 50 6.86 1.351
T41 1215-1240 Sentence denotes Oral cavity 32 6.23 1.271
T42 1241-1260 Sentence denotes Lung 110 5.83 0.710
T43 1261-1282 Sentence denotes Thyroid 59 5.65 0.646
T44 1283-1306 Sentence denotes Esophagus 11 5.31 1.552
T45 1307-1328 Sentence denotes Bladder 19 5.10 1.809
T46 1329-1350 Sentence denotes Breast 113 4.61 0.961
T47 1351-1371 Sentence denotes Uterus 25 4.37 1.125
T48 1372-1394 Sentence denotes Prostate 52 4.35 1.905
T49 1395-1515 Sentence denotes To investigate the ACE2 expression on mucosa of oral cavity, we looked into the ACE2 expression in different oral sites.
T50 1516-1823 Sentence denotes According to the site information provided by the TCGA, among the 32 adjacent normal tissues, 13 tissues located in the oral tongue, 2 tissues located in the base of tongue, 3 tissues located in the floor of mouse, and 14 tissues did not definite the site and were just put into the category of oral cavity.
T51 1824-1897 Sentence denotes The mean expression distribution of different sites was shown in Fig. 1c.
T52 1898-2252 Sentence denotes When we combined the base of tongue, floor of mouth and oral cavity as other sites, and compared them with oral tongue, we found the obvious tendency that the mean expression of ACE2 was higher in oral tongue (13 tissues) than others (19 tissues) (Fig. 1d), while may due to the limitation of the sample size, the p value was not significant (P = 0.062).
T53 2254-2298 Sentence denotes Single cell RNA-seq analysis of oral tissues
T54 2299-2463 Sentence denotes Single cell RNA-seq was utilized for four oral tissues, and the data was analyzed to confirm the above results and assess the cell type-specific expression of ACE2.
T55 2464-3079 Sentence denotes After the data preprocessing (shown in section “Materials and methods”), 22 969 cells were acquired and 7 cell types were identified (Fig. 2a), including epithelial cells (marker genes including SFN, KRT6A, and KRT10), fibroblasts (marker genes including FAP, PDPN, COL1A2, DCN, COL3A1, COL6A1), T cells (marker genes including CD2, CD3D, CD3E, and CD3G), macrophages (marker genes including CD163, CSF1R, CD68, and FCGR2A), mast cells (marker genes including CMA1, MS4A2, TPSAB1, TPSB2), B cells (marker genes including SLAMF7, FCRL5, and CD79A) and endothelial cells (marker genes including PECAM1, VWF, and ENG).
T56 3080-3159 Sentence denotes The heatmap of main cell markers across the cell types can be found in Fig. 2b.
T57 3160-3627 Sentence denotes Fig. 2 Single cell RNA-seq analysis of oral tissues from independent dataset. a Seven-cell types were identified by the cell markers; cells were clustered by UMAP method. b Heatmap of cell markers for identifying cell types. c Scatter plots of all the cells with ACE2 expression. d Violin plot of ACE2 expression across different oral sites. e Violin plot of ACE2 expression across different cell types. f Scatter plots of tongue epithelial cells with ACE2 expression
T58 3628-3845 Sentence denotes According to Fig. 2c, d, we confirmed the ACE2 was expressed in oral tissues (0.52% ACE2-positive cells), and higher in oral tongue than buccal and gingival tissues (95.86% ACE2-positive cells located in oral tongue).
T59 3846-4163 Sentence denotes Figure 2e shows that the ACE2-positive cells could be found in oral tissues including epithelial cells (1.19% ACE2-positive cells), T cells (<0.5%), B cells (<0.5%), and fibroblast (<0.5%), and the ACE2 was highly enriched in epithelial cells, of which 93.38% ACE2-positive cells belong to epithelial cells (Fig. 2f).
T60 4164-4315 Sentence denotes The above results indicated that the ACE2 could be expressed on the epithelial cells of the oral mucosa and highly enriched in tongue epithelial cells.