PMC:7039956 / 11079-11668 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"316","span":{"begin":39,"end":43},"obj":"Gene"},{"id":"317","span":{"begin":142,"end":146},"obj":"Gene"},{"id":"318","span":{"begin":221,"end":225},"obj":"Gene"},{"id":"319","span":{"begin":380,"end":384},"obj":"Gene"},{"id":"320","span":{"begin":523,"end":532},"obj":"Species"},{"id":"321","span":{"begin":503,"end":512},"obj":"Disease"}],"attributes":[{"id":"A316","pred":"tao:has_database_id","subj":"316","obj":"Gene:59272"},{"id":"A317","pred":"tao:has_database_id","subj":"317","obj":"Gene:59272"},{"id":"A318","pred":"tao:has_database_id","subj":"318","obj":"Gene:59272"},{"id":"A319","pred":"tao:has_database_id","subj":"319","obj":"Gene:59272"},{"id":"A320","pred":"tao:has_database_id","subj":"320","obj":"Tax:2697049"},{"id":"A321","pred":"tao:has_database_id","subj":"321","obj":"MESH:D007239"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Previous studies have investigated the ACE2 mRNA and protein expression in various tissues by bulk samples17,18, however, the distribution of ACE2 through bulk data could not indicate the cell type-specific expression of ACE2. Recently developed single-cell RNA-sequencing technology enabled the generation of vast amounts of the transcriptomic data at cellular resolution19. The ACE2 expression profile in various organs, tissues, and cell types, provides the bioinformatics evidence for the potential infection routes of 2019-nCov, which might also be associated with presented symptoms."}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T200","span":{"begin":44,"end":48},"obj":"Body_part"},{"id":"T201","span":{"begin":53,"end":60},"obj":"Body_part"},{"id":"T202","span":{"begin":83,"end":90},"obj":"Body_part"},{"id":"T203","span":{"begin":188,"end":192},"obj":"Body_part"},{"id":"T204","span":{"begin":253,"end":257},"obj":"Body_part"},{"id":"T205","span":{"begin":258,"end":261},"obj":"Body_part"},{"id":"T206","span":{"begin":423,"end":430},"obj":"Body_part"},{"id":"T207","span":{"begin":436,"end":440},"obj":"Body_part"}],"attributes":[{"id":"A200","pred":"fma_id","subj":"T200","obj":"http://purl.org/sig/ont/fma/fma67122"},{"id":"A201","pred":"fma_id","subj":"T201","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A202","pred":"fma_id","subj":"T202","obj":"http://purl.org/sig/ont/fma/fma9637"},{"id":"A203","pred":"fma_id","subj":"T203","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A204","pred":"fma_id","subj":"T204","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A205","pred":"fma_id","subj":"T205","obj":"http://purl.org/sig/ont/fma/fma67095"},{"id":"A206","pred":"fma_id","subj":"T206","obj":"http://purl.org/sig/ont/fma/fma9637"},{"id":"A207","pred":"fma_id","subj":"T207","obj":"http://purl.org/sig/ont/fma/fma68646"}],"text":"Previous studies have investigated the ACE2 mRNA and protein expression in various tissues by bulk samples17,18, however, the distribution of ACE2 through bulk data could not indicate the cell type-specific expression of ACE2. Recently developed single-cell RNA-sequencing technology enabled the generation of vast amounts of the transcriptomic data at cellular resolution19. The ACE2 expression profile in various organs, tissues, and cell types, provides the bioinformatics evidence for the potential infection routes of 2019-nCov, which might also be associated with presented symptoms."}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T80","span":{"begin":415,"end":421},"obj":"Body_part"}],"attributes":[{"id":"A80","pred":"uberon_id","subj":"T80","obj":"http://purl.obolibrary.org/obo/UBERON_0000062"}],"text":"Previous studies have investigated the ACE2 mRNA and protein expression in various tissues by bulk samples17,18, however, the distribution of ACE2 through bulk data could not indicate the cell type-specific expression of ACE2. Recently developed single-cell RNA-sequencing technology enabled the generation of vast amounts of the transcriptomic data at cellular resolution19. The ACE2 expression profile in various organs, tissues, and cell types, provides the bioinformatics evidence for the potential infection routes of 2019-nCov, which might also be associated with presented symptoms."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T35","span":{"begin":503,"end":512},"obj":"Disease"}],"attributes":[{"id":"A35","pred":"mondo_id","subj":"T35","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"}],"text":"Previous studies have investigated the ACE2 mRNA and protein expression in various tissues by bulk samples17,18, however, the distribution of ACE2 through bulk data could not indicate the cell type-specific expression of ACE2. Recently developed single-cell RNA-sequencing technology enabled the generation of vast amounts of the transcriptomic data at cellular resolution19. The ACE2 expression profile in various organs, tissues, and cell types, provides the bioinformatics evidence for the potential infection routes of 2019-nCov, which might also be associated with presented symptoms."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T222","span":{"begin":188,"end":197},"obj":"http://purl.obolibrary.org/obo/CL_0000000"},{"id":"T223","span":{"begin":253,"end":257},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T224","span":{"begin":415,"end":421},"obj":"http://purl.obolibrary.org/obo/UBERON_0003103"},{"id":"T225","span":{"begin":436,"end":446},"obj":"http://purl.obolibrary.org/obo/CL_0000000"}],"text":"Previous studies have investigated the ACE2 mRNA and protein expression in various tissues by bulk samples17,18, however, the distribution of ACE2 through bulk data could not indicate the cell type-specific expression of ACE2. Recently developed single-cell RNA-sequencing technology enabled the generation of vast amounts of the transcriptomic data at cellular resolution19. The ACE2 expression profile in various organs, tissues, and cell types, provides the bioinformatics evidence for the potential infection routes of 2019-nCov, which might also be associated with presented symptoms."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T15","span":{"begin":53,"end":60},"obj":"Chemical"}],"attributes":[{"id":"A15","pred":"chebi_id","subj":"T15","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"}],"text":"Previous studies have investigated the ACE2 mRNA and protein expression in various tissues by bulk samples17,18, however, the distribution of ACE2 through bulk data could not indicate the cell type-specific expression of ACE2. Recently developed single-cell RNA-sequencing technology enabled the generation of vast amounts of the transcriptomic data at cellular resolution19. The ACE2 expression profile in various organs, tissues, and cell types, provides the bioinformatics evidence for the potential infection routes of 2019-nCov, which might also be associated with presented symptoms."}

{"project":"LitCovid-sentences","denotations":[{"id":"T74","span":{"begin":0,"end":226},"obj":"Sentence"},{"id":"T75","span":{"begin":227,"end":375},"obj":"Sentence"},{"id":"T76","span":{"begin":376,"end":589},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Previous studies have investigated the ACE2 mRNA and protein expression in various tissues by bulk samples17,18, however, the distribution of ACE2 through bulk data could not indicate the cell type-specific expression of ACE2. Recently developed single-cell RNA-sequencing technology enabled the generation of vast amounts of the transcriptomic data at cellular resolution19. The ACE2 expression profile in various organs, tissues, and cell types, provides the bioinformatics evidence for the potential infection routes of 2019-nCov, which might also be associated with presented symptoms."}

{"project":"2_test","denotations":[{"id":"32094336-12459472-53457435","span":{"begin":106,"end":108},"obj":"12459472"},{"id":"32094336-15141377-53457436","span":{"begin":109,"end":111},"obj":"15141377"},{"id":"32094336-28524227-53457437","span":{"begin":372,"end":374},"obj":"28524227"},{"id":"T48696","span":{"begin":106,"end":108},"obj":"12459472"},{"id":"T75300","span":{"begin":109,"end":111},"obj":"15141377"},{"id":"T20570","span":{"begin":372,"end":374},"obj":"28524227"}],"text":"Previous studies have investigated the ACE2 mRNA and protein expression in various tissues by bulk samples17,18, however, the distribution of ACE2 through bulk data could not indicate the cell type-specific expression of ACE2. Recently developed single-cell RNA-sequencing technology enabled the generation of vast amounts of the transcriptomic data at cellular resolution19. The ACE2 expression profile in various organs, tissues, and cell types, provides the bioinformatics evidence for the potential infection routes of 2019-nCov, which might also be associated with presented symptoms."}