PMC:7039956 / 10181-10657 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"298","span":{"begin":62,"end":66},"obj":"Gene"},{"id":"299","span":{"begin":111,"end":115},"obj":"Gene"},{"id":"300","span":{"begin":245,"end":249},"obj":"Gene"},{"id":"301","span":{"begin":440,"end":460},"obj":"Disease"}],"attributes":[{"id":"A298","pred":"tao:has_database_id","subj":"298","obj":"Gene:59272"},{"id":"A299","pred":"tao:has_database_id","subj":"299","obj":"Gene:59272"},{"id":"A300","pred":"tao:has_database_id","subj":"300","obj":"Gene:59272"},{"id":"A301","pred":"tao:has_database_id","subj":"301","obj":"MESH:C000657245"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"The results of our single cell RNA-seq profiles validated the ACE2 expression in oral cavity, and the level of ACE2 expression in oral tissues was higher in tongue than buccal or gingival tissues. Furthermore, we have also demonstrated that the ACE2-positive cells were enriched in epithelial cells, which was also reported by previous study10–12,16. These findings indicated that oral cavity could be regarded as potentially high risk for 2019-nCov infectious susceptibility."}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T184","span":{"begin":26,"end":30},"obj":"Body_part"},{"id":"T185","span":{"begin":31,"end":34},"obj":"Body_part"},{"id":"T186","span":{"begin":81,"end":92},"obj":"Body_part"},{"id":"T187","span":{"begin":135,"end":142},"obj":"Body_part"},{"id":"T188","span":{"begin":157,"end":163},"obj":"Body_part"},{"id":"T189","span":{"begin":188,"end":195},"obj":"Body_part"},{"id":"T190","span":{"begin":259,"end":264},"obj":"Body_part"},{"id":"T191","span":{"begin":282,"end":298},"obj":"Body_part"},{"id":"T192","span":{"begin":293,"end":298},"obj":"Body_part"},{"id":"T193","span":{"begin":381,"end":392},"obj":"Body_part"}],"attributes":[{"id":"A184","pred":"fma_id","subj":"T184","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A185","pred":"fma_id","subj":"T185","obj":"http://purl.org/sig/ont/fma/fma67095"},{"id":"A186","pred":"fma_id","subj":"T186","obj":"http://purl.org/sig/ont/fma/fma20292"},{"id":"A187","pred":"fma_id","subj":"T187","obj":"http://purl.org/sig/ont/fma/fma9637"},{"id":"A188","pred":"fma_id","subj":"T188","obj":"http://purl.org/sig/ont/fma/fma54640"},{"id":"A189","pred":"fma_id","subj":"T189","obj":"http://purl.org/sig/ont/fma/fma9637"},{"id":"A190","pred":"fma_id","subj":"T190","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A191","pred":"fma_id","subj":"T191","obj":"http://purl.org/sig/ont/fma/fma66768"},{"id":"A192","pred":"fma_id","subj":"T192","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A193","pred":"fma_id","subj":"T193","obj":"http://purl.org/sig/ont/fma/fma20292"}],"text":"The results of our single cell RNA-seq profiles validated the ACE2 expression in oral cavity, and the level of ACE2 expression in oral tissues was higher in tongue than buccal or gingival tissues. Furthermore, we have also demonstrated that the ACE2-positive cells were enriched in epithelial cells, which was also reported by previous study10–12,16. These findings indicated that oral cavity could be regarded as potentially high risk for 2019-nCov infectious susceptibility."}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T74","span":{"begin":81,"end":92},"obj":"Body_part"},{"id":"T75","span":{"begin":157,"end":163},"obj":"Body_part"},{"id":"T76","span":{"begin":381,"end":392},"obj":"Body_part"}],"attributes":[{"id":"A74","pred":"uberon_id","subj":"T74","obj":"http://purl.obolibrary.org/obo/UBERON_0000167"},{"id":"A75","pred":"uberon_id","subj":"T75","obj":"http://purl.obolibrary.org/obo/UBERON_0001723"},{"id":"A76","pred":"uberon_id","subj":"T76","obj":"http://purl.obolibrary.org/obo/UBERON_0000167"}],"text":"The results of our single cell RNA-seq profiles validated the ACE2 expression in oral cavity, and the level of ACE2 expression in oral tissues was higher in tongue than buccal or gingival tissues. Furthermore, we have also demonstrated that the ACE2-positive cells were enriched in epithelial cells, which was also reported by previous study10–12,16. These findings indicated that oral cavity could be regarded as potentially high risk for 2019-nCov infectious susceptibility."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T34","span":{"begin":450,"end":460},"obj":"Disease"}],"attributes":[{"id":"A34","pred":"mondo_id","subj":"T34","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"}],"text":"The results of our single cell RNA-seq profiles validated the ACE2 expression in oral cavity, and the level of ACE2 expression in oral tissues was higher in tongue than buccal or gingival tissues. Furthermore, we have also demonstrated that the ACE2-positive cells were enriched in epithelial cells, which was also reported by previous study10–12,16. These findings indicated that oral cavity could be regarded as potentially high risk for 2019-nCov infectious susceptibility."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T209","span":{"begin":26,"end":30},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T210","span":{"begin":81,"end":92},"obj":"http://purl.obolibrary.org/obo/UBERON_0000167"},{"id":"T211","span":{"begin":81,"end":92},"obj":"http://www.ebi.ac.uk/efo/EFO_0000825"},{"id":"T212","span":{"begin":157,"end":163},"obj":"http://purl.obolibrary.org/obo/UBERON_0001723"},{"id":"T213","span":{"begin":259,"end":264},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T214","span":{"begin":282,"end":292},"obj":"http://purl.obolibrary.org/obo/CL_0000066"},{"id":"T215","span":{"begin":293,"end":298},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T216","span":{"begin":381,"end":392},"obj":"http://purl.obolibrary.org/obo/UBERON_0000167"},{"id":"T217","span":{"begin":381,"end":392},"obj":"http://www.ebi.ac.uk/efo/EFO_0000825"}],"text":"The results of our single cell RNA-seq profiles validated the ACE2 expression in oral cavity, and the level of ACE2 expression in oral tissues was higher in tongue than buccal or gingival tissues. Furthermore, we have also demonstrated that the ACE2-positive cells were enriched in epithelial cells, which was also reported by previous study10–12,16. These findings indicated that oral cavity could be regarded as potentially high risk for 2019-nCov infectious susceptibility."}

{"project":"LitCovid-sentences","denotations":[{"id":"T69","span":{"begin":0,"end":196},"obj":"Sentence"},{"id":"T70","span":{"begin":197,"end":350},"obj":"Sentence"},{"id":"T71","span":{"begin":351,"end":476},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"The results of our single cell RNA-seq profiles validated the ACE2 expression in oral cavity, and the level of ACE2 expression in oral tissues was higher in tongue than buccal or gingival tissues. Furthermore, we have also demonstrated that the ACE2-positive cells were enriched in epithelial cells, which was also reported by previous study10–12,16. These findings indicated that oral cavity could be regarded as potentially high risk for 2019-nCov infectious susceptibility."}

{"project":"2_test","denotations":[{"id":"32094336-16690935-53457434","span":{"begin":347,"end":349},"obj":"16690935"},{"id":"T71659","span":{"begin":347,"end":349},"obj":"16690935"}],"text":"The results of our single cell RNA-seq profiles validated the ACE2 expression in oral cavity, and the level of ACE2 expression in oral tissues was higher in tongue than buccal or gingival tissues. Furthermore, we have also demonstrated that the ACE2-positive cells were enriched in epithelial cells, which was also reported by previous study10–12,16. These findings indicated that oral cavity could be regarded as potentially high risk for 2019-nCov infectious susceptibility."}