PMC:7036342 / 1711-2460 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7036342","sourcedb":"PMC","sourceid":"7036342","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7036342","text":"Since December 2019, 2019 novel CoV (SARS-CoV-2) has been making a large outbreak involving 49,053 laboratory-confirmed patients and 1,383 mortality in 25 countries including Korea until February 14, 2020.2 In the outbreak situation, isolation of causative virus is indispensable for developing and evaluating diagnostic tools, therapeutics, and vaccine candidates. SARS-CoV-2 was first isolated using human airway epithelial cells and it was classified into the subgenus sarbecovirus of beta-CoVs by phylogenetic analyses of the gene sequences.3 Both the SARS-CoV and the MERS-CoV were initially isolated and grew readily in Vero cells.45 Here, we report the isolation of SARS-CoV-2 using Vero cells from a patient entering Korea from Wuhan, 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