PMC:7036338 / 12068-14776 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"175","span":{"begin":1252,"end":1254},"obj":"CellLine"},{"id":"177","span":{"begin":1309,"end":1311},"obj":"CellLine"},{"id":"179","span":{"begin":1363,"end":1365},"obj":"CellLine"},{"id":"181","span":{"begin":1537,"end":1539},"obj":"CellLine"}],"attributes":[{"id":"A175","pred":"tao:has_database_id","subj":"175","obj":"CVCL:7028"},{"id":"A177","pred":"tao:has_database_id","subj":"177","obj":"CVCL:7028"},{"id":"A179","pred":"tao:has_database_id","subj":"179","obj":"CVCL:7028"},{"id":"A181","pred":"tao:has_database_id","subj":"181","obj":"CVCL:7028"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"ACKNOWLEDGMENTS\nWe greatly appreciate the efforts of all the hospital employees and their families at the Incheon Medical Center and National Medical Center, who are working tirelessly during this outbreak. We thank to Yoonju Oh, Sung Hee Kim, Yoon Soog Kang, and Kwang Sil Kim (Incheon Medical Center) for collecting and preserving clinical specimens. We thank Hyun Mee Park (Department of Radiology, National Medical Center) for the obtainment of excellent radiologic study result safely. We also thank to Yunyoung Jang, and Eunhee Kim for the dedication to protect healthcare workers of National Medical Center by infection control. We sincerely appreciate the discussion and critical feedback from Dr. Janet A Englund (Seattle Children’s Hospital, Seattle, WA, USA). Lastly, we thank all the members of the Korean Society of Infectious Diseases (KSID), the groups of Korean Emerging Infectious Diseases (KoEID) application, and Korea National Clinical Management Network (KNCMN) for COVID-19, who are coping with the current global outbreak situation together. Disclosure: The authors have no potential conflicts of interest to disclose.\nAuthor Contributions: Conceptualization: Kim JY, Chin BS, Kim YJ.\nData curation: Kim JY, Chin BS, Han MG, Kim SY, Ko JH.\nFormal analysis: Kim JY, Chin BS, Han MG, Kim SY, Ko JH.\nMethodology: Kim JM, Chung YS, Kim HM, Kim SY, Han MG.\nWriting - original draft: Kim YJ, Kim JY, Chin BS, Han MG, Ko JH.\nWriting - review \u0026 editing: Kim JY, Ko JH, Kim Y, Kim YJ, Kim JM, Chung YS, Kim HM, Han MG, Kim SY, Chin BS.\n\nSUPPLEMENTARY MATERIALS\nSupplementary Data 1\nLaboratory procedures and detailed clinical course of Patient 2\nSupplementary Table 1\nClinical course and viral loads of Patient 1 according to the timeline from symptom onset\nSupplementary Table 2\nClinical course and viral loads of Patient 2 according to the timeline from symptom onset\nSupplementary Table 3\nEstimated number of viral copy of respiratory specimens\nSupplementary Fig. 1\nViral load kinetics according to the clinical course of Patient 1, presented by reverse Ct value. (A) Viral load kinetics of respiratory specimen, (B) Viral load kinetics of blood specimen, (C) Viral load kinetics of urine and stool specimen.\nSupplementary Fig. 2\nViral load kinetics according to the clinical course of Patient 2, presented by reverse Ct value. (A) Viral load kinetics of respiratory specimen, (B) Viral load kinetics of blood specimen, (C) Viral load kinetics of urine and stool specimen.\nSupplementary Fig. 3\nImages of Patient 2. (A) Chest X-ray taken on admission, January 24, 2010 (day 15 from symptom onset). (B) High resolution computed tomography taken on January 25, 2010 (day 16 from symptom onset)."}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T77","span":{"begin":1191,"end":1195},"obj":"Body_part"},{"id":"T78","span":{"begin":1231,"end":1235},"obj":"Body_part"},{"id":"T79","span":{"begin":1288,"end":1292},"obj":"Body_part"},{"id":"T80","span":{"begin":1417,"end":1421},"obj":"Body_part"},{"id":"T81","span":{"begin":1541,"end":1545},"obj":"Body_part"},{"id":"T82","span":{"begin":2157,"end":2162},"obj":"Body_part"},{"id":"T83","span":{"begin":2200,"end":2205},"obj":"Body_part"},{"id":"T84","span":{"begin":2210,"end":2215},"obj":"Body_part"},{"id":"T85","span":{"begin":2421,"end":2426},"obj":"Body_part"},{"id":"T86","span":{"begin":2464,"end":2469},"obj":"Body_part"},{"id":"T87","span":{"begin":2474,"end":2479},"obj":"Body_part"},{"id":"T88","span":{"begin":2536,"end":2541},"obj":"Body_part"}],"attributes":[{"id":"A77","pred":"fma_id","subj":"T77","obj":"http://purl.org/sig/ont/fma/fma46495"},{"id":"A78","pred":"fma_id","subj":"T78","obj":"http://purl.org/sig/ont/fma/fma46495"},{"id":"A79","pred":"fma_id","subj":"T79","obj":"http://purl.org/sig/ont/fma/fma46495"},{"id":"A80","pred":"fma_id","subj":"T80","obj":"http://purl.org/sig/ont/fma/fma46495"},{"id":"A81","pred":"fma_id","subj":"T81","obj":"http://purl.org/sig/ont/fma/fma46495"},{"id":"A82","pred":"fma_id","subj":"T82","obj":"http://purl.org/sig/ont/fma/fma9670"},{"id":"A83","pred":"fma_id","subj":"T83","obj":"http://purl.org/sig/ont/fma/fma12274"},{"id":"A84","pred":"fma_id","subj":"T84","obj":"http://purl.org/sig/ont/fma/fma64183"},{"id":"A85","pred":"fma_id","subj":"T85","obj":"http://purl.org/sig/ont/fma/fma9670"},{"id":"A86","pred":"fma_id","subj":"T86","obj":"http://purl.org/sig/ont/fma/fma12274"},{"id":"A87","pred":"fma_id","subj":"T87","obj":"http://purl.org/sig/ont/fma/fma64183"},{"id":"A88","pred":"fma_id","subj":"T88","obj":"http://purl.org/sig/ont/fma/fma9576"}],"text":"ACKNOWLEDGMENTS\nWe greatly appreciate the efforts of all the hospital employees and their families at the Incheon Medical Center and National Medical Center, who are working tirelessly during this outbreak. We thank to Yoonju Oh, Sung Hee Kim, Yoon Soog Kang, and Kwang Sil Kim (Incheon Medical Center) for collecting and preserving clinical specimens. We thank Hyun Mee Park (Department of Radiology, National Medical Center) for the obtainment of excellent radiologic study result safely. We also thank to Yunyoung Jang, and Eunhee Kim for the dedication to protect healthcare workers of National Medical Center by infection control. We sincerely appreciate the discussion and critical feedback from Dr. Janet A Englund (Seattle Children’s Hospital, Seattle, WA, USA). Lastly, we thank all the members of the Korean Society of Infectious Diseases (KSID), the groups of Korean Emerging Infectious Diseases (KoEID) application, and Korea National Clinical Management Network (KNCMN) for COVID-19, who are coping with the current global outbreak situation together. Disclosure: The authors have no potential conflicts of interest to disclose.\nAuthor Contributions: Conceptualization: Kim JY, Chin BS, Kim YJ.\nData curation: Kim JY, Chin BS, Han MG, Kim SY, Ko JH.\nFormal analysis: Kim JY, Chin BS, Han MG, Kim SY, Ko JH.\nMethodology: Kim JM, Chung YS, Kim HM, Kim SY, Han MG.\nWriting - original draft: Kim YJ, Kim JY, Chin BS, Han MG, Ko JH.\nWriting - review \u0026 editing: Kim JY, Ko JH, Kim Y, Kim YJ, Kim JM, Chung YS, Kim HM, Han MG, Kim SY, Chin BS.\n\nSUPPLEMENTARY MATERIALS\nSupplementary Data 1\nLaboratory procedures and detailed clinical course of Patient 2\nSupplementary Table 1\nClinical course and viral loads of Patient 1 according to the timeline from symptom onset\nSupplementary Table 2\nClinical course and viral loads of Patient 2 according to the timeline from symptom onset\nSupplementary Table 3\nEstimated number of viral copy of respiratory specimens\nSupplementary Fig. 1\nViral load kinetics according to the clinical course of Patient 1, presented by reverse Ct value. (A) Viral load kinetics of respiratory specimen, (B) Viral load kinetics of blood specimen, (C) Viral load kinetics of urine and stool specimen.\nSupplementary Fig. 2\nViral load kinetics according to the clinical course of Patient 2, presented by reverse Ct value. (A) Viral load kinetics of respiratory specimen, (B) Viral load kinetics of blood specimen, (C) Viral load kinetics of urine and stool specimen.\nSupplementary Fig. 3\nImages of Patient 2. (A) Chest X-ray taken on admission, January 24, 2010 (day 15 from symptom onset). (B) High resolution computed tomography taken on January 25, 2010 (day 16 from symptom onset)."}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T44","span":{"begin":1191,"end":1195},"obj":"Body_part"},{"id":"T45","span":{"begin":1231,"end":1235},"obj":"Body_part"},{"id":"T46","span":{"begin":1288,"end":1292},"obj":"Body_part"},{"id":"T47","span":{"begin":1417,"end":1421},"obj":"Body_part"},{"id":"T48","span":{"begin":1541,"end":1545},"obj":"Body_part"},{"id":"T49","span":{"begin":2157,"end":2162},"obj":"Body_part"},{"id":"T50","span":{"begin":2200,"end":2205},"obj":"Body_part"},{"id":"T51","span":{"begin":2210,"end":2215},"obj":"Body_part"},{"id":"T52","span":{"begin":2421,"end":2426},"obj":"Body_part"},{"id":"T53","span":{"begin":2464,"end":2469},"obj":"Body_part"},{"id":"T54","span":{"begin":2474,"end":2479},"obj":"Body_part"},{"id":"T55","span":{"begin":2536,"end":2541},"obj":"Body_part"}],"attributes":[{"id":"A44","pred":"uberon_id","subj":"T44","obj":"http://purl.obolibrary.org/obo/UBERON_0008199"},{"id":"A45","pred":"uberon_id","subj":"T45","obj":"http://purl.obolibrary.org/obo/UBERON_0008199"},{"id":"A46","pred":"uberon_id","subj":"T46","obj":"http://purl.obolibrary.org/obo/UBERON_0008199"},{"id":"A47","pred":"uberon_id","subj":"T47","obj":"http://purl.obolibrary.org/obo/UBERON_0008199"},{"id":"A48","pred":"uberon_id","subj":"T48","obj":"http://purl.obolibrary.org/obo/UBERON_0008199"},{"id":"A49","pred":"uberon_id","subj":"T49","obj":"http://purl.obolibrary.org/obo/UBERON_0000178"},{"id":"A50","pred":"uberon_id","subj":"T50","obj":"http://purl.obolibrary.org/obo/UBERON_0001088"},{"id":"A51","pred":"uberon_id","subj":"T51","obj":"http://purl.obolibrary.org/obo/UBERON_0001988"},{"id":"A52","pred":"uberon_id","subj":"T52","obj":"http://purl.obolibrary.org/obo/UBERON_0000178"},{"id":"A53","pred":"uberon_id","subj":"T53","obj":"http://purl.obolibrary.org/obo/UBERON_0001088"},{"id":"A54","pred":"uberon_id","subj":"T54","obj":"http://purl.obolibrary.org/obo/UBERON_0001988"},{"id":"A55","pred":"uberon_id","subj":"T55","obj":"http://purl.obolibrary.org/obo/UBERON_0001443"}],"text":"ACKNOWLEDGMENTS\nWe greatly appreciate the efforts of all the hospital employees and their families at the Incheon Medical Center and National Medical Center, who are working tirelessly during this outbreak. We thank to Yoonju Oh, Sung Hee Kim, Yoon Soog Kang, and Kwang Sil Kim (Incheon Medical Center) for collecting and preserving clinical specimens. We thank Hyun Mee Park (Department of Radiology, National Medical Center) for the obtainment of excellent radiologic study result safely. We also thank to Yunyoung Jang, and Eunhee Kim for the dedication to protect healthcare workers of National Medical Center by infection control. We sincerely appreciate the discussion and critical feedback from Dr. Janet A Englund (Seattle Children’s Hospital, Seattle, WA, USA). Lastly, we thank all the members of the Korean Society of Infectious Diseases (KSID), the groups of Korean Emerging Infectious Diseases (KoEID) application, and Korea National Clinical Management Network (KNCMN) for COVID-19, who are coping with the current global outbreak situation together. Disclosure: The authors have no potential conflicts of interest to disclose.\nAuthor Contributions: Conceptualization: Kim JY, Chin BS, Kim YJ.\nData curation: Kim JY, Chin BS, Han MG, Kim SY, Ko JH.\nFormal analysis: Kim JY, Chin BS, Han MG, Kim SY, Ko JH.\nMethodology: Kim JM, Chung YS, Kim HM, Kim SY, Han MG.\nWriting - original draft: Kim YJ, Kim JY, Chin BS, Han MG, Ko JH.\nWriting - review \u0026 editing: Kim JY, Ko JH, Kim Y, Kim YJ, Kim JM, Chung YS, Kim HM, Han MG, Kim SY, Chin BS.\n\nSUPPLEMENTARY MATERIALS\nSupplementary Data 1\nLaboratory procedures and detailed clinical course of Patient 2\nSupplementary Table 1\nClinical course and viral loads of Patient 1 according to the timeline from symptom onset\nSupplementary Table 2\nClinical course and viral loads of Patient 2 according to the timeline from symptom onset\nSupplementary Table 3\nEstimated number of viral copy of respiratory specimens\nSupplementary Fig. 1\nViral load kinetics according to the clinical course of Patient 1, presented by reverse Ct value. (A) Viral load kinetics of respiratory specimen, (B) Viral load kinetics of blood specimen, (C) Viral load kinetics of urine and stool specimen.\nSupplementary Fig. 2\nViral load kinetics according to the clinical course of Patient 2, presented by reverse Ct value. (A) Viral load kinetics of respiratory specimen, (B) Viral load kinetics of blood specimen, (C) Viral load kinetics of urine and stool specimen.\nSupplementary Fig. 3\nImages of Patient 2. (A) Chest X-ray taken on admission, January 24, 2010 (day 15 from symptom onset). (B) High resolution computed tomography taken on January 25, 2010 (day 16 from symptom onset)."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T42","span":{"begin":617,"end":626},"obj":"Disease"},{"id":"T43","span":{"begin":829,"end":839},"obj":"Disease"},{"id":"T44","span":{"begin":887,"end":897},"obj":"Disease"},{"id":"T45","span":{"begin":987,"end":995},"obj":"Disease"},{"id":"T46","span":{"begin":1196,"end":1198},"obj":"Disease"},{"id":"T47","span":{"begin":1236,"end":1238},"obj":"Disease"},{"id":"T48","span":{"begin":1293,"end":1295},"obj":"Disease"},{"id":"T49","span":{"begin":1422,"end":1424},"obj":"Disease"},{"id":"T50","span":{"begin":1546,"end":1548},"obj":"Disease"}],"attributes":[{"id":"A42","pred":"mondo_id","subj":"T42","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A43","pred":"mondo_id","subj":"T43","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A44","pred":"mondo_id","subj":"T44","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A45","pred":"mondo_id","subj":"T45","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A46","pred":"mondo_id","subj":"T46","obj":"http://purl.obolibrary.org/obo/MONDO_0008876"},{"id":"A47","pred":"mondo_id","subj":"T47","obj":"http://purl.obolibrary.org/obo/MONDO_0008876"},{"id":"A48","pred":"mondo_id","subj":"T48","obj":"http://purl.obolibrary.org/obo/MONDO_0008876"},{"id":"A49","pred":"mondo_id","subj":"T49","obj":"http://purl.obolibrary.org/obo/MONDO_0008876"},{"id":"A50","pred":"mondo_id","subj":"T50","obj":"http://purl.obolibrary.org/obo/MONDO_0008876"}],"text":"ACKNOWLEDGMENTS\nWe greatly appreciate the efforts of all the hospital employees and their families at the Incheon Medical Center and National Medical Center, who are working tirelessly during this outbreak. We thank to Yoonju Oh, Sung Hee Kim, Yoon Soog Kang, and Kwang Sil Kim (Incheon Medical Center) for collecting and preserving clinical specimens. We thank Hyun Mee Park (Department of Radiology, National Medical Center) for the obtainment of excellent radiologic study result safely. We also thank to Yunyoung Jang, and Eunhee Kim for the dedication to protect healthcare workers of National Medical Center by infection control. We sincerely appreciate the discussion and critical feedback from Dr. Janet A Englund (Seattle Children’s Hospital, Seattle, WA, USA). Lastly, we thank all the members of the Korean Society of Infectious Diseases (KSID), the groups of Korean Emerging Infectious Diseases (KoEID) application, and Korea National Clinical Management Network (KNCMN) for COVID-19, who are coping with the current global outbreak situation together. Disclosure: The authors have no potential conflicts of interest to disclose.\nAuthor Contributions: Conceptualization: Kim JY, Chin BS, Kim YJ.\nData curation: Kim JY, Chin BS, Han MG, Kim SY, Ko JH.\nFormal analysis: Kim JY, Chin BS, Han MG, Kim SY, Ko JH.\nMethodology: Kim JM, Chung YS, Kim HM, Kim SY, Han MG.\nWriting - original draft: Kim YJ, Kim JY, Chin BS, Han MG, Ko JH.\nWriting - review \u0026 editing: Kim JY, Ko JH, Kim Y, Kim YJ, Kim JM, Chung YS, Kim HM, Han MG, Kim SY, Chin BS.\n\nSUPPLEMENTARY MATERIALS\nSupplementary Data 1\nLaboratory procedures and detailed clinical course of Patient 2\nSupplementary Table 1\nClinical course and viral loads of Patient 1 according to the timeline from symptom onset\nSupplementary Table 2\nClinical course and viral loads of Patient 2 according to the timeline from symptom onset\nSupplementary Table 3\nEstimated number of viral copy of respiratory specimens\nSupplementary Fig. 1\nViral load kinetics according to the clinical course of Patient 1, presented by reverse Ct value. (A) Viral load kinetics of respiratory specimen, (B) Viral load kinetics of blood specimen, (C) Viral load kinetics of urine and stool specimen.\nSupplementary Fig. 2\nViral load kinetics according to the clinical course of Patient 2, presented by reverse Ct value. (A) Viral load kinetics of respiratory specimen, (B) Viral load kinetics of blood specimen, (C) Viral load kinetics of urine and stool specimen.\nSupplementary Fig. 3\nImages of Patient 2. (A) Chest X-ray taken on admission, January 24, 2010 (day 15 from symptom onset). (B) High resolution computed tomography taken on January 25, 2010 (day 16 from symptom onset)."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T64","span":{"begin":712,"end":713},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T65","span":{"begin":1337,"end":1339},"obj":"http://purl.obolibrary.org/obo/CLO_0007029"},{"id":"T66","span":{"begin":1337,"end":1339},"obj":"http://purl.obolibrary.org/obo/CLO_0050993"},{"id":"T67","span":{"begin":1503,"end":1505},"obj":"http://purl.obolibrary.org/obo/CLO_0007029"},{"id":"T68","span":{"begin":1503,"end":1505},"obj":"http://purl.obolibrary.org/obo/CLO_0050993"},{"id":"T69","span":{"begin":2082,"end":2083},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T70","span":{"begin":2131,"end":2132},"obj":"http://purl.obolibrary.org/obo/CLO_0001021"},{"id":"T71","span":{"begin":2157,"end":2162},"obj":"http://purl.obolibrary.org/obo/UBERON_0000178"},{"id":"T72","span":{"begin":2157,"end":2162},"obj":"http://www.ebi.ac.uk/efo/EFO_0000296"},{"id":"T73","span":{"begin":2346,"end":2347},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T74","span":{"begin":2395,"end":2396},"obj":"http://purl.obolibrary.org/obo/CLO_0001021"},{"id":"T75","span":{"begin":2421,"end":2426},"obj":"http://purl.obolibrary.org/obo/UBERON_0000178"},{"id":"T76","span":{"begin":2421,"end":2426},"obj":"http://www.ebi.ac.uk/efo/EFO_0000296"},{"id":"T77","span":{"begin":2529,"end":2535},"obj":"http://purl.obolibrary.org/obo/CLO_0001236"},{"id":"T78","span":{"begin":2536,"end":2541},"obj":"http://www.ebi.ac.uk/efo/EFO_0000965"},{"id":"T79","span":{"begin":2615,"end":2616},"obj":"http://purl.obolibrary.org/obo/CLO_0001021"}],"text":"ACKNOWLEDGMENTS\nWe greatly appreciate the efforts of all the hospital employees and their families at the Incheon Medical Center and National Medical Center, who are working tirelessly during this outbreak. We thank to Yoonju Oh, Sung Hee Kim, Yoon Soog Kang, and Kwang Sil Kim (Incheon Medical Center) for collecting and preserving clinical specimens. We thank Hyun Mee Park (Department of Radiology, National Medical Center) for the obtainment of excellent radiologic study result safely. We also thank to Yunyoung Jang, and Eunhee Kim for the dedication to protect healthcare workers of National Medical Center by infection control. We sincerely appreciate the discussion and critical feedback from Dr. Janet A Englund (Seattle Children’s Hospital, Seattle, WA, USA). Lastly, we thank all the members of the Korean Society of Infectious Diseases (KSID), the groups of Korean Emerging Infectious Diseases (KoEID) application, and Korea National Clinical Management Network (KNCMN) for COVID-19, who are coping with the current global outbreak situation together. Disclosure: The authors have no potential conflicts of interest to disclose.\nAuthor Contributions: Conceptualization: Kim JY, Chin BS, Kim YJ.\nData curation: Kim JY, Chin BS, Han MG, Kim SY, Ko JH.\nFormal analysis: Kim JY, Chin BS, Han MG, Kim SY, Ko JH.\nMethodology: Kim JM, Chung YS, Kim HM, Kim SY, Han MG.\nWriting - original draft: Kim YJ, Kim JY, Chin BS, Han MG, Ko JH.\nWriting - review \u0026 editing: Kim JY, Ko JH, Kim Y, Kim YJ, Kim JM, Chung YS, Kim HM, Han MG, Kim SY, Chin BS.\n\nSUPPLEMENTARY MATERIALS\nSupplementary Data 1\nLaboratory procedures and detailed clinical course of Patient 2\nSupplementary Table 1\nClinical course and viral loads of Patient 1 according to the timeline from symptom onset\nSupplementary Table 2\nClinical course and viral loads of Patient 2 according to the timeline from symptom onset\nSupplementary Table 3\nEstimated number of viral copy of respiratory specimens\nSupplementary Fig. 1\nViral load kinetics according to the clinical course of Patient 1, presented by reverse Ct value. (A) Viral load kinetics of respiratory specimen, (B) Viral load kinetics of blood specimen, (C) Viral load kinetics of urine and stool specimen.\nSupplementary Fig. 2\nViral load kinetics according to the clinical course of Patient 2, presented by reverse Ct value. (A) Viral load kinetics of respiratory specimen, (B) Viral load kinetics of blood specimen, (C) Viral load kinetics of urine and stool specimen.\nSupplementary Fig. 3\nImages of Patient 2. (A) Chest X-ray taken on admission, January 24, 2010 (day 15 from symptom onset). (B) High resolution computed tomography taken on January 25, 2010 (day 16 from symptom onset)."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T14","span":{"begin":761,"end":763},"obj":"Chemical"},{"id":"T15","span":{"begin":915,"end":926},"obj":"Chemical"},{"id":"T16","span":{"begin":1244,"end":1246},"obj":"Chemical"},{"id":"T17","span":{"begin":1252,"end":1254},"obj":"Chemical"},{"id":"T18","span":{"begin":1256,"end":1258},"obj":"Chemical"},{"id":"T19","span":{"begin":1301,"end":1303},"obj":"Chemical"},{"id":"T20","span":{"begin":1309,"end":1311},"obj":"Chemical"},{"id":"T21","span":{"begin":1313,"end":1315},"obj":"Chemical"},{"id":"T22","span":{"begin":1337,"end":1339},"obj":"Chemical"},{"id":"T23","span":{"begin":1347,"end":1349},"obj":"Chemical"},{"id":"T24","span":{"begin":1355,"end":1357},"obj":"Chemical"},{"id":"T25","span":{"begin":1363,"end":1365},"obj":"Chemical"},{"id":"T26","span":{"begin":1371,"end":1373},"obj":"Chemical"},{"id":"T27","span":{"begin":1430,"end":1432},"obj":"Chemical"},{"id":"T28","span":{"begin":1434,"end":1436},"obj":"Chemical"},{"id":"T29","span":{"begin":1477,"end":1479},"obj":"Chemical"},{"id":"T30","span":{"begin":1503,"end":1505},"obj":"Chemical"},{"id":"T31","span":{"begin":1513,"end":1515},"obj":"Chemical"},{"id":"T32","span":{"begin":1521,"end":1523},"obj":"Chemical"},{"id":"T33","span":{"begin":1529,"end":1531},"obj":"Chemical"},{"id":"T34","span":{"begin":1537,"end":1539},"obj":"Chemical"}],"attributes":[{"id":"A14","pred":"chebi_id","subj":"T14","obj":"http://purl.obolibrary.org/obo/CHEBI_73710"},{"id":"A15","pred":"chebi_id","subj":"T15","obj":"http://purl.obolibrary.org/obo/CHEBI_33232"},{"id":"A16","pred":"chebi_id","subj":"T16","obj":"http://purl.obolibrary.org/obo/CHEBI_73611"},{"id":"A17","pred":"chebi_id","subj":"T17","obj":"http://purl.obolibrary.org/obo/CHEBI_73652"},{"id":"A18","pred":"chebi_id","subj":"T18","obj":"http://purl.obolibrary.org/obo/CHEBI_59348"},{"id":"A19","pred":"chebi_id","subj":"T19","obj":"http://purl.obolibrary.org/obo/CHEBI_73611"},{"id":"A20","pred":"chebi_id","subj":"T20","obj":"http://purl.obolibrary.org/obo/CHEBI_73652"},{"id":"A21","pred":"chebi_id","subj":"T21","obj":"http://purl.obolibrary.org/obo/CHEBI_59348"},{"id":"A22","pred":"chebi_id","subj":"T22","obj":"http://purl.obolibrary.org/obo/CHEBI_31739"},{"id":"A23","pred":"chebi_id","subj":"T23","obj":"http://purl.obolibrary.org/obo/CHEBI_141457"},{"id":"A24","pred":"chebi_id","subj":"T24","obj":"http://purl.obolibrary.org/obo/CHEBI_74053"},{"id":"A25","pred":"chebi_id","subj":"T25","obj":"http://purl.obolibrary.org/obo/CHEBI_73652"},{"id":"A26","pred":"chebi_id","subj":"T26","obj":"http://purl.obolibrary.org/obo/CHEBI_73611"},{"id":"A27","pred":"chebi_id","subj":"T27","obj":"http://purl.obolibrary.org/obo/CHEBI_73611"},{"id":"A28","pred":"chebi_id","subj":"T28","obj":"http://purl.obolibrary.org/obo/CHEBI_59348"},{"id":"A29","pred":"chebi_id","subj":"T29","obj":"http://purl.obolibrary.org/obo/CHEBI_59348"},{"id":"A30","pred":"chebi_id","subj":"T30","obj":"http://purl.obolibrary.org/obo/CHEBI_31739"},{"id":"A31","pred":"chebi_id","subj":"T31","obj":"http://purl.obolibrary.org/obo/CHEBI_141457"},{"id":"A32","pred":"chebi_id","subj":"T32","obj":"http://purl.obolibrary.org/obo/CHEBI_74053"},{"id":"A33","pred":"chebi_id","subj":"T33","obj":"http://purl.obolibrary.org/obo/CHEBI_73611"},{"id":"A34","pred":"chebi_id","subj":"T34","obj":"http://purl.obolibrary.org/obo/CHEBI_73652"}],"text":"ACKNOWLEDGMENTS\nWe greatly appreciate the efforts of all the hospital employees and their families at the Incheon Medical Center and National Medical Center, who are working tirelessly during this outbreak. We thank to Yoonju Oh, Sung Hee Kim, Yoon Soog Kang, and Kwang Sil Kim (Incheon Medical Center) for collecting and preserving clinical specimens. We thank Hyun Mee Park (Department of Radiology, National Medical Center) for the obtainment of excellent radiologic study result safely. We also thank to Yunyoung Jang, and Eunhee Kim for the dedication to protect healthcare workers of National Medical Center by infection control. We sincerely appreciate the discussion and critical feedback from Dr. Janet A Englund (Seattle Children’s Hospital, Seattle, WA, USA). Lastly, we thank all the members of the Korean Society of Infectious Diseases (KSID), the groups of Korean Emerging Infectious Diseases (KoEID) application, and Korea National Clinical Management Network (KNCMN) for COVID-19, who are coping with the current global outbreak situation together. Disclosure: The authors have no potential conflicts of interest to disclose.\nAuthor Contributions: Conceptualization: Kim JY, Chin BS, Kim YJ.\nData curation: Kim JY, Chin BS, Han MG, Kim SY, Ko JH.\nFormal analysis: Kim JY, Chin BS, Han MG, Kim SY, Ko JH.\nMethodology: Kim JM, Chung YS, Kim HM, Kim SY, Han MG.\nWriting - original draft: Kim YJ, Kim JY, Chin BS, Han MG, Ko JH.\nWriting - review \u0026 editing: Kim JY, Ko JH, Kim Y, Kim YJ, Kim JM, Chung YS, Kim HM, Han MG, Kim SY, Chin BS.\n\nSUPPLEMENTARY MATERIALS\nSupplementary Data 1\nLaboratory procedures and detailed clinical course of Patient 2\nSupplementary Table 1\nClinical course and viral loads of Patient 1 according to the timeline from symptom onset\nSupplementary Table 2\nClinical course and viral loads of Patient 2 according to the timeline from symptom onset\nSupplementary Table 3\nEstimated number of viral copy of respiratory specimens\nSupplementary Fig. 1\nViral load kinetics according to the clinical course of Patient 1, presented by reverse Ct value. (A) Viral load kinetics of respiratory specimen, (B) Viral load kinetics of blood specimen, (C) Viral load kinetics of urine and stool specimen.\nSupplementary Fig. 2\nViral load kinetics according to the clinical course of Patient 2, presented by reverse Ct value. (A) Viral load kinetics of respiratory specimen, (B) Viral load kinetics of blood specimen, (C) Viral load kinetics of urine and stool specimen.\nSupplementary Fig. 3\nImages of Patient 2. (A) Chest X-ray taken on admission, January 24, 2010 (day 15 from symptom onset). (B) High resolution computed tomography taken on January 25, 2010 (day 16 from symptom onset)."}

{"project":"LitCovid-sentences","denotations":[{"id":"T85","span":{"begin":0,"end":15},"obj":"Sentence"},{"id":"T86","span":{"begin":16,"end":206},"obj":"Sentence"},{"id":"T87","span":{"begin":207,"end":352},"obj":"Sentence"},{"id":"T88","span":{"begin":353,"end":490},"obj":"Sentence"},{"id":"T89","span":{"begin":491,"end":635},"obj":"Sentence"},{"id":"T90","span":{"begin":636,"end":770},"obj":"Sentence"},{"id":"T91","span":{"begin":771,"end":1064},"obj":"Sentence"},{"id":"T92","span":{"begin":1065,"end":1076},"obj":"Sentence"},{"id":"T93","span":{"begin":1077,"end":1141},"obj":"Sentence"},{"id":"T94","span":{"begin":1142,"end":1163},"obj":"Sentence"},{"id":"T95","span":{"begin":1164,"end":1182},"obj":"Sentence"},{"id":"T96","span":{"begin":1183,"end":1207},"obj":"Sentence"},{"id":"T97","span":{"begin":1208,"end":1222},"obj":"Sentence"},{"id":"T98","span":{"begin":1223,"end":1262},"obj":"Sentence"},{"id":"T99","span":{"begin":1263,"end":1279},"obj":"Sentence"},{"id":"T100","span":{"begin":1280,"end":1319},"obj":"Sentence"},{"id":"T101","span":{"begin":1320,"end":1332},"obj":"Sentence"},{"id":"T102","span":{"begin":1333,"end":1374},"obj":"Sentence"},{"id":"T103","span":{"begin":1375,"end":1400},"obj":"Sentence"},{"id":"T104","span":{"begin":1401,"end":1440},"obj":"Sentence"},{"id":"T105","span":{"begin":1441,"end":1468},"obj":"Sentence"},{"id":"T106","span":{"begin":1469,"end":1549},"obj":"Sentence"},{"id":"T107","span":{"begin":1551,"end":1574},"obj":"Sentence"},{"id":"T108","span":{"begin":1575,"end":1595},"obj":"Sentence"},{"id":"T109","span":{"begin":1596,"end":1659},"obj":"Sentence"},{"id":"T110","span":{"begin":1660,"end":1681},"obj":"Sentence"},{"id":"T111","span":{"begin":1682,"end":1771},"obj":"Sentence"},{"id":"T112","span":{"begin":1772,"end":1793},"obj":"Sentence"},{"id":"T113","span":{"begin":1794,"end":1883},"obj":"Sentence"},{"id":"T114","span":{"begin":1884,"end":1905},"obj":"Sentence"},{"id":"T115","span":{"begin":1906,"end":1961},"obj":"Sentence"},{"id":"T116","span":{"begin":1962,"end":1982},"obj":"Sentence"},{"id":"T117","span":{"begin":1983,"end":2225},"obj":"Sentence"},{"id":"T118","span":{"begin":2226,"end":2246},"obj":"Sentence"},{"id":"T119","span":{"begin":2247,"end":2489},"obj":"Sentence"},{"id":"T120","span":{"begin":2490,"end":2510},"obj":"Sentence"},{"id":"T121","span":{"begin":2511,"end":2708},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"ACKNOWLEDGMENTS\nWe greatly appreciate the efforts of all the hospital employees and their families at the Incheon Medical Center and National Medical Center, who are working tirelessly during this outbreak. We thank to Yoonju Oh, Sung Hee Kim, Yoon Soog Kang, and Kwang Sil Kim (Incheon Medical Center) for collecting and preserving clinical specimens. We thank Hyun Mee Park (Department of Radiology, National Medical Center) for the obtainment of excellent radiologic study result safely. We also thank to Yunyoung Jang, and Eunhee Kim for the dedication to protect healthcare workers of National Medical Center by infection control. We sincerely appreciate the discussion and critical feedback from Dr. Janet A Englund (Seattle Children’s Hospital, Seattle, WA, USA). Lastly, we thank all the members of the Korean Society of Infectious Diseases (KSID), the groups of Korean Emerging Infectious Diseases (KoEID) application, and Korea National Clinical Management Network (KNCMN) for COVID-19, who are coping with the current global outbreak situation together. Disclosure: The authors have no potential conflicts of interest to disclose.\nAuthor Contributions: Conceptualization: Kim JY, Chin BS, Kim YJ.\nData curation: Kim JY, Chin BS, Han MG, Kim SY, Ko JH.\nFormal analysis: Kim JY, Chin BS, Han MG, Kim SY, Ko JH.\nMethodology: Kim JM, Chung YS, Kim HM, Kim SY, Han MG.\nWriting - original draft: Kim YJ, Kim JY, Chin BS, Han MG, Ko JH.\nWriting - review \u0026 editing: Kim JY, Ko JH, Kim Y, Kim YJ, Kim JM, Chung YS, Kim HM, Han MG, Kim SY, Chin BS.\n\nSUPPLEMENTARY MATERIALS\nSupplementary Data 1\nLaboratory procedures and detailed clinical course of Patient 2\nSupplementary Table 1\nClinical course and viral loads of Patient 1 according to the timeline from symptom onset\nSupplementary Table 2\nClinical course and viral loads of Patient 2 according to the timeline from symptom onset\nSupplementary Table 3\nEstimated number of viral copy of respiratory specimens\nSupplementary Fig. 1\nViral load kinetics according to the clinical course of Patient 1, presented by reverse Ct value. (A) Viral load kinetics of respiratory specimen, (B) Viral load kinetics of blood specimen, (C) Viral load kinetics of urine and stool specimen.\nSupplementary Fig. 2\nViral load kinetics according to the clinical course of Patient 2, presented by reverse Ct value. (A) Viral load kinetics of respiratory specimen, (B) Viral load kinetics of blood specimen, (C) Viral load kinetics of urine and stool specimen.\nSupplementary Fig. 3\nImages of Patient 2. (A) Chest X-ray taken on admission, January 24, 2010 (day 15 from symptom onset). (B) High resolution computed tomography taken on January 25, 2010 (day 16 from symptom onset)."}