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PMC:7035340 / 1776-4000 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
52 47-55 Species denotes patients Tax:9606
53 61-70 Species denotes 2019-nCoV Tax:2697049
64 587-591 Species denotes H1N1 Tax:114727
65 841-849 Species denotes patients Tax:9606
66 115-126 Disease denotes lung injury MESH:D055370
67 163-172 Disease denotes pneumonia MESH:D011014
68 263-300 Disease denotes dysfunctional systematic inflammation MESH:D007249
69 367-394 Disease denotes novel coronavirus pneumonia MESH:C000657245
70 396-399 Disease denotes NCP MESH:C000657245
71 546-562 Disease denotes viral pneumonias
72 572-576 Disease denotes SARS MESH:D045169
73 578-582 Disease denotes MERS MESH:D018352
94 1788-1792 Gene denotes HIN1 Gene:54726
95 1473-1481 Species denotes patients Tax:9606
96 1659-1667 Species denotes patients Tax:9606
97 2010-2018 Species denotes patients Tax:9606
98 2024-2033 Species denotes 2019-nCoV Tax:2697049
99 2090-2098 Species denotes patients Tax:9606
100 1195-1204 Disease denotes mortality MESH:D003643
101 1210-1222 Disease denotes septic shock MESH:D012772
102 1241-1256 Disease denotes lung infections MESH:D012141
103 1346-1351 Disease denotes shock MESH:D012769
104 1496-1500 Disease denotes ARDS MESH:D012128
105 1521-1539 Disease denotes pulmonary fibrosis MESH:D011658
106 1673-1677 Disease denotes SARS MESH:D045169
107 1678-1687 Disease denotes infection MESH:D007239
108 1751-1760 Disease denotes mortality MESH:D003643
109 1995-2009 Disease denotes critically ill MESH:D016638
110 2086-2089 Disease denotes NCP MESH:C000657245
111 2154-2158 Disease denotes ARDS MESH:D012128
112 2160-2166 Disease denotes sepsis MESH:D018805
113 2170-2182 Disease denotes septic shock MESH:D012772

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T2 115-119 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T3 1241-1245 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 115-119 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T2 1241-1245 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T14 120-126 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T15 163-172 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T16 385-394 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T17 546-562 Disease denotes viral pneumonias http://purl.obolibrary.org/obo/MONDO_0006012
T18 572-576 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T19 1246-1256 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T20 1496-1500 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T21 1521-1539 Disease denotes pulmonary fibrosis http://purl.obolibrary.org/obo/MONDO_0002771
T22 1673-1677 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T23 1678-1687 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T24 2154-2158 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T5 115-119 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T6 115-119 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T7 1081-1082 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T8 1241-1245 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T9 1241-1245 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T10 1609-1610 http://purl.obolibrary.org/obo/CLO_0001020 denotes a

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T7 8-23 Chemical denotes corticosteroids http://purl.obolibrary.org/obo/CHEBI_50858
T8 337-352 Chemical denotes corticosteroids http://purl.obolibrary.org/obo/CHEBI_50858
T9 518-533 Chemical denotes corticosteroids http://purl.obolibrary.org/obo/CHEBI_50858
T10 671-686 Chemical denotes corticosteroids http://purl.obolibrary.org/obo/CHEBI_50858
T11 804-819 Chemical denotes corticosteroids http://purl.obolibrary.org/obo/CHEBI_50858
T12 1029-1044 Chemical denotes corticosteroids http://purl.obolibrary.org/obo/CHEBI_50858
T13 1154-1169 Chemical denotes corticosteroids http://purl.obolibrary.org/obo/CHEBI_50858
T14 1436-1451 Chemical denotes corticosteroids http://purl.obolibrary.org/obo/CHEBI_50858
T15 1708-1723 Chemical denotes corticosteroids http://purl.obolibrary.org/obo/CHEBI_50858
T16 1829-1834 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T17 1945-1960 Chemical denotes corticosteroids http://purl.obolibrary.org/obo/CHEBI_50858

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T4 163-172 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T5 385-394 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T6 552-562 Phenotype denotes pneumonias http://purl.obolibrary.org/obo/HP_0002090
T7 1217-1222 Phenotype denotes shock http://purl.obolibrary.org/obo/HP_0031273
T8 1346-1351 Phenotype denotes shock http://purl.obolibrary.org/obo/HP_0031273
T9 1521-1539 Phenotype denotes pulmonary fibrosis http://purl.obolibrary.org/obo/HP_0002206
T10 2160-2166 Phenotype denotes sepsis http://purl.obolibrary.org/obo/HP_0100806
T11 2177-2182 Phenotype denotes shock http://purl.obolibrary.org/obo/HP_0031273

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T13 0-71 Sentence denotes Salvage corticosteroids treatment for critical patients with 2019-nCoV?
T14 72-302 Sentence denotes Corticosteroids are widely used to prevent lung injury caused by severe community-acquired pneumonia (sCAP) due to their excellent pharmacological effects on the suppression of exuberant and dysfunctional systematic inflammation5.
T15 303-593 Sentence denotes Some scholars may not support the corticosteroids treatment for novel coronavirus pneumonia (NCP), because observational studies and systematic reviews have indicated inconclusive clinical evidence on the effect of corticosteroids therapy for viral pneumonias (such as SARS, MERS and H1N1).
T16 594-742 Sentence denotes Additionally, pulse-dose therapy or long-term administration to high dose of corticosteroids in early stage were reported to be possibly harmful6–8.
T17 743-1054 Sentence denotes However, these conclusions obscured the clinical benefits of corticosteroids on some subgroups of patients, particularly those with severe symptoms, as the clinical effects might be related to the indication (severities of illness), the timing of intervention, the dose and duration of corticosteroids therapy9.
T18 1055-1418 Sentence denotes Of note, as documented in a series of randomized clinical trials (RCT), low or physiologic dose of corticosteroids treatment did not reduce mortality from septic shock caused by primary lung infections, but it could bring clinical benefits to secondary outcomes, such as earlier reversal of shock, shorter duration to exit from ICU and mechanical ventilation9,10.
T19 1419-1732 Sentence denotes Besides, salvage corticosteroids treatment for severe patients with advanced ARDS could alleviate the pulmonary fibrosis and prevent progressive pathological deterioration11, which provides a good framework for explaining why some critical patients with SARS infection benefit from rescue corticosteroids therapy.
T20 1733-1870 Sentence denotes More importantly, mortality benefit favored the severe HIN1-illness in the adjunctive treatment group with low dose of corticosteroids12.
T21 1871-2224 Sentence denotes Evidently, all these results strongly suggest that proper use of low-dose corticosteroids may bring survival advantages for critically ill patients with 2019-nCoV, but this treatment should be strictly performed on NCP patients with definite clinical indications (such as refractory ARDS, sepsis or septic shock) according to the recommended guidelines.

2_test

Id Subject Object Predicate Lexical cue
32296012-31261585-139944471 300-301 31261585 denotes 5
32296012-29161116-139944472 738-739 29161116 denotes 6
32296012-16968120-139944472 738-739 16968120 denotes 6
32296012-30074052-139944472 738-739 30074052 denotes 6
32296012-29849191-139944473 1052-1053 29849191 denotes 9
32296012-29849191-139944474 1413-1414 29849191 denotes 9
32296012-28098591-139944475 1415-1417 28098591 denotes 10
32296012-7492007-139944476 1590-1592 7492007 denotes 11
32296012-28464462-139944477 1867-1869 28464462 denotes 12