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PMC:7033706 / 181-7988 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
9 111-119 Species denotes patients Tax:9606
10 336-341 Species denotes human Tax:9606
11 384-401 Species denotes novel coronavirus Tax:2697049
12 403-412 Species denotes 2019-nCoV Tax:2697049
13 36-45 Disease denotes pneumonia MESH:D011014
25 565-574 Species denotes 2019-nCoV Tax:2697049
26 639-647 Species denotes patients Tax:9606
27 794-809 Species denotes new-coronavirus Tax:2697049
28 875-883 Species denotes patients Tax:9606
29 962-971 Species denotes 2019-nCoV Tax:2697049
30 1070-1078 Species denotes patients Tax:9606
31 1138-1143 Species denotes human Tax:9606
32 1147-1152 Species denotes human Tax:9606
33 1169-1178 Species denotes 2019-nCoV Tax:2697049
34 1222-1237 Species denotes new-coronavirus Tax:2697049
35 1060-1069 Disease denotes pneumonia MESH:D011014
46 2324-2329 Gene denotes spike Gene:43740568
47 2814-2815 Gene denotes S Gene:43740568
48 2568-2569 Gene denotes S Gene:43740568
49 2381-2382 Gene denotes S Gene:43740568
50 2314-2323 Species denotes 2019-nCoV Tax:2697049
51 2391-2400 Species denotes 2019-nCoV Tax:2697049
52 2449-2457 Species denotes SARS-CoV Tax:694009
53 2468-2481 Species denotes coronaviruses Tax:11118
54 2581-2590 Species denotes 2019-nCoV Tax:2697049
55 2804-2813 Species denotes 2019-nCoV Tax:2697049
69 1349-1358 Species denotes 2019-nCoV Tax:2697049
70 1480-1484 Species denotes nCoV Tax:2697049
71 1513-1538 Species denotes bat SARS-like coronavirus Tax:1508227
72 1641-1649 Species denotes SARS-CoV Tax:694009
73 1683-1692 Species denotes 2019-nCoV Tax:2697049
74 1709-1724 Species denotes betacoronavirus Tax:694002
75 1803-1811 Species denotes SARS-CoV Tax:694009
76 1840-1843 Species denotes CoV Tax:11118
77 1881-1895 Species denotes horseshoe bats Tax:49442
78 2015-2019 Species denotes rats Tax:10116
79 2111-2120 Species denotes 2019-nCoV Tax:2697049
80 1403-1411 CellLine denotes MN908947 CVCL:U508
81 1577-1587 CellLine denotes MG772934.1 CVCL:8732
101 4860-4864 Gene denotes SC-1 Gene:6941
102 5256-5260 Gene denotes SC-1 Gene:6941
103 5120-5121 Gene denotes S Gene:43740568
104 3812-3813 Gene denotes S Gene:43740568
105 2918-2935 Species denotes novel coronavirus Tax:2697049
106 3325-3344 Species denotes novel coronaviruses Tax:2697049
107 3357-3363 Species denotes humans Tax:9606
108 3448-3457 Species denotes 2019-nCoV Tax:2697049
109 3563-3574 Species denotes coronavirus Tax:11118
110 3752-3761 Species denotes 2019-nCoV Tax:2697049
111 3802-3811 Species denotes 2019-nCoV Tax:2697049
112 3845-3853 Species denotes SARS-CoV Tax:694009
113 3873-3877 Species denotes CoVs Tax:11118
114 4840-4848 Species denotes SARS-CoV Tax:694009
115 5110-5119 Species denotes 2019-nCoV Tax:2697049
116 5164-5172 Species denotes SARS-CoV Tax:694009
117 2989-3016 Disease denotes respiratory virus infection
118 3537-3546 Disease denotes pneumonia MESH:D011014
119 5310-5329 Disease denotes 2019-nCoV infection MESH:C000657245
135 5633-5637 Gene denotes DPP4 Gene:1803
136 5378-5381 Species denotes CoV Tax:11118
137 5451-5456 Species denotes human Tax:9606
138 5457-5470 Species denotes coronaviruses Tax:11118
139 5482-5490 Species denotes SARS-CoV Tax:694009
140 5495-5503 Species denotes MERS-CoV Tax:1335626
141 5522-5526 Species denotes CoVs Tax:11118
142 5627-5632 Species denotes human Tax:9606
143 5638-5653 Species denotes transgenic mice Tax:10090
144 5908-5917 Species denotes 2019-nCoV Tax:2697049
145 5937-5950 Species denotes coronaviruses Tax:11118
146 5433-5442 Disease denotes infection MESH:D007239
147 5664-5677 Disease denotes CoV infection MESH:D018352
148 5748-5767 Disease denotes 2019-nCoV infection MESH:C000657245
149 5895-5904 Disease denotes infection MESH:D007239
163 6417-6418 Gene denotes S Gene:43740568
164 6399-6400 Gene denotes S Gene:43740568
165 5978-5986 Species denotes SARS-CoV Tax:694009
166 5991-5999 Species denotes MERS-CoV Tax:1335626
167 6142-6150 Species denotes SARS-CoV Tax:694009
168 6247-6255 Species denotes MERS-CoV Tax:1335626
169 6389-6398 Species denotes 2019-nCoV Tax:2697049
170 6432-6443 Species denotes coronavirus Tax:11118
171 6474-6483 Species denotes 2019-nCoV Tax:2697049
172 6538-6549 Species denotes coronavirus Tax:11118
173 6556-6565 Species denotes 2019-nCoV Tax:2697049
174 6155-6174 Disease denotes MERS-CoV infections MESH:D018352
175 6354-6367 Disease denotes CoV infection MESH:D018352
183 6842-6843 Gene denotes S Gene:43740568
184 6636-6644 Species denotes SARS-CoV Tax:694009
185 6649-6657 Species denotes MERS-CoV Tax:1335626
186 6832-6841 Species denotes 2019-nCoV Tax:2697049
187 6897-6906 Species denotes 2019-nCoV Tax:2697049
188 6999-7007 Species denotes SARS-CoV Tax:694009
189 7015-7023 Species denotes MERS-CoV Tax:1335626
199 7472-7480 Species denotes SARS-CoV Tax:694009
200 7553-7557 Species denotes CoVs Tax:11118
201 7574-7577 Species denotes CoV Tax:11118
202 7594-7597 Species denotes CoV Tax:11118
203 7658-7667 Species denotes 2019-nCoV Tax:2697049
204 7343-7351 Species denotes SARS-CoV Tax:694009
205 7255-7274 Disease denotes 2019-nCoV infection MESH:C000657245
206 7432-7451 Disease denotes 2019-nCoV infection MESH:C000657245
207 7787-7806 Disease denotes 2019-nCoV infection MESH:C000657245

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T1 1458-1462 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T2 2330-2337 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T3 2346-2350 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T4 2383-2387 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T5 2570-2577 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T6 2760-2771 Body_part denotes cytoplasmic http://purl.org/sig/ont/fma/fma66835
T7 3713-3717 Body_part denotes iris http://purl.org/sig/ont/fma/fma58235
T8 3814-3821 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T9 4182-4186 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T10 4542-4555 Body_part denotes cell membrane http://purl.org/sig/ont/fma/fma63841
T11 4542-4546 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T12 4669-4687 Body_part denotes cellular membranes http://purl.org/sig/ont/fma/fma63841
T13 4737-4741 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T14 4789-4793 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T15 4851-4858 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T16 4906-4913 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T17 5037-5044 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T18 5094-5098 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T19 5227-5238 Body_part denotes amino acids http://purl.org/sig/ont/fma/fma82739
T20 6214-6221 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T21 6262-6272 Body_part denotes amino acid http://purl.org/sig/ont/fma/fma82739
T22 6776-6783 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 3713-3717 Body_part denotes iris http://purl.obolibrary.org/obo/UBERON_0001769
T2 4761-4765 Body_part denotes pore http://purl.obolibrary.org/obo/UBERON_0008915

LitCovid_AGAC

Id Subject Object Predicate Lexical cue
p5527s40 4983-4997 MPA denotes 6-HB formation

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T2 36-45 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T3 1060-1069 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T4 1517-1521 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T5 1641-1649 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T6 1803-1811 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T7 2449-2457 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T8 2612-2615 Disease denotes NTD http://purl.obolibrary.org/obo/MONDO_0008449|http://purl.obolibrary.org/obo/MONDO_0018075
T10 3001-3016 Disease denotes virus infection http://purl.obolibrary.org/obo/MONDO_0005108
T11 3007-3016 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T12 3537-3546 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T13 3845-3853 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T14 4052-4055 Disease denotes NTD http://purl.obolibrary.org/obo/MONDO_0008449|http://purl.obolibrary.org/obo/MONDO_0018075
T16 4840-4848 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T17 5164-5172 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T18 5310-5329 Disease denotes 2019-nCoV infection http://purl.obolibrary.org/obo/MONDO_0100096
T19 5320-5329 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T20 5433-5442 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T21 5482-5490 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T22 5668-5677 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T23 5748-5767 Disease denotes 2019-nCoV infection http://purl.obolibrary.org/obo/MONDO_0100096
T24 5758-5767 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T25 5895-5904 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T26 5978-5986 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T27 6142-6150 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T28 6164-6174 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T29 6358-6367 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T30 6636-6644 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T31 6985-6988 Disease denotes NTD http://purl.obolibrary.org/obo/MONDO_0008449|http://purl.obolibrary.org/obo/MONDO_0018075
T33 6999-7007 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T34 7255-7274 Disease denotes 2019-nCoV infection http://purl.obolibrary.org/obo/MONDO_0100096
T35 7265-7274 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T36 7343-7351 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T37 7432-7451 Disease denotes 2019-nCoV infection http://purl.obolibrary.org/obo/MONDO_0100096
T38 7442-7451 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T39 7472-7480 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T40 7787-7806 Disease denotes 2019-nCoV infection http://purl.obolibrary.org/obo/MONDO_0100096
T41 7797-7806 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T1 135-136 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T2 204-211 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes animals
T3 232-236 http://purl.obolibrary.org/obo/NCBITaxon_9397 denotes bats
T4 261-268 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes animals
T5 326-332 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes animal
T6 336-341 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T7 382-383 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T8 491-492 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T9 683-685 http://purl.obolibrary.org/obo/CLO_0001000 denotes 35
T10 1138-1143 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T11 1147-1152 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T12 1458-1462 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T13 1513-1516 http://purl.obolibrary.org/obo/NCBITaxon_9397 denotes bat
T14 1546-1549 http://purl.obolibrary.org/obo/NCBITaxon_9397 denotes bat
T15 1733-1734 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T16 1740-1743 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T17 1763-1766 http://purl.obolibrary.org/obo/NCBITaxon_9397 denotes bat
T18 1782-1785 http://purl.obolibrary.org/obo/NCBITaxon_9397 denotes bat
T19 1833-1836 http://purl.obolibrary.org/obo/NCBITaxon_9397 denotes bat
T20 1891-1895 http://purl.obolibrary.org/obo/NCBITaxon_9397 denotes bats
T21 2066-2070 http://purl.obolibrary.org/obo/NCBITaxon_9397 denotes bats
T22 2080-2087 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes animals
T23 2144-2148 http://purl.obolibrary.org/obo/NCBITaxon_9397 denotes bats
T24 2157-2164 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes animals
T25 2209-2212 http://purl.obolibrary.org/obo/NCBITaxon_9397 denotes bat
T26 2346-2350 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T27 2353-2354 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T28 2383-2387 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T29 2415-2418 http://purl.obolibrary.org/obo/NCBITaxon_9397 denotes bat
T30 2432-2435 http://purl.obolibrary.org/obo/NCBITaxon_9397 denotes bat
T31 2514-2515 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T32 2596-2602 http://purl.obolibrary.org/obo/SO_0000418 denotes signal
T33 2603-2610 http://purl.obolibrary.org/obo/PR_000018263 denotes peptide
T34 2677-2684 http://purl.obolibrary.org/obo/PR_000018263 denotes peptide
T35 2756-2758 http://purl.obolibrary.org/obo/PR_000005794 denotes CP
T36 3001-3006 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T37 3357-3363 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humans
T38 3377-3384 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes animals
T39 3407-3413 http://purl.obolibrary.org/obo/NCBITaxon_33208 denotes animal
T40 3557-3558 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T41 3559-3562 http://purl.obolibrary.org/obo/NCBITaxon_9596 denotes pan
T42 3866-3869 http://purl.obolibrary.org/obo/NCBITaxon_9397 denotes bat
T43 3930-3932 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T44 3937-3939 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T45 3937-3939 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T46 3985-3987 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T47 4061-4062 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T48 4182-4186 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T49 4263-4264 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T50 4329-4331 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T51 4329-4331 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T52 4382-4389 http://purl.obolibrary.org/obo/PR_000018263 denotes peptide
T53 4452-4454 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T54 4476-4478 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T55 4476-4478 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T56 4542-4546 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T57 4547-4555 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T58 4622-4624 http://purl.obolibrary.org/obo/CLO_0003622 denotes HB
T59 4678-4687 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membranes
T60 4737-4741 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T61 4789-4793 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T62 4799-4800 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T63 4801-4808 http://purl.obolibrary.org/obo/PR_000018263 denotes peptide
T64 4860-4864 http://purl.obolibrary.org/obo/CLO_0008956 denotes SC-1
T65 4860-4864 http://purl.obolibrary.org/obo/CLO_0008957 denotes SC-1
T66 4860-4864 http://purl.obolibrary.org/obo/CLO_0008958 denotes SC-1
T67 4860-4864 http://purl.obolibrary.org/obo/CLO_0050606 denotes SC-1
T68 4937-4939 http://purl.obolibrary.org/obo/CLO_0003622 denotes HB
T69 4985-4987 http://purl.obolibrary.org/obo/CLO_0003622 denotes HB
T70 5094-5098 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T71 5195-5196 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T72 5256-5260 http://purl.obolibrary.org/obo/CLO_0008956 denotes SC-1
T73 5256-5260 http://purl.obolibrary.org/obo/CLO_0008957 denotes SC-1
T74 5256-5260 http://purl.obolibrary.org/obo/CLO_0008958 denotes SC-1
T75 5256-5260 http://purl.obolibrary.org/obo/CLO_0050606 denotes SC-1
T76 5261-5268 http://purl.obolibrary.org/obo/PR_000018263 denotes peptide
T77 5372-5373 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T78 5374-5377 http://purl.obolibrary.org/obo/NCBITaxon_9596 denotes pan
T79 5404-5411 http://purl.obolibrary.org/obo/PR_000018263 denotes peptide
T80 5451-5456 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T81 5515-5518 http://purl.obolibrary.org/obo/NCBITaxon_9397 denotes bat
T82 5562-5569 http://purl.obolibrary.org/obo/PR_000018263 denotes peptide
T83 5607-5614 http://purl.obolibrary.org/obo/PR_000018263 denotes peptide
T84 5627-5632 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T85 5805-5812 http://purl.obolibrary.org/obo/PR_000018263 denotes peptide
T86 5816-5817 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T87 6262-6281 http://purl.obolibrary.org/obo/CHEBI_33708 denotes amino acid residues
T88 6262-6281 http://purl.obolibrary.org/obo/PR_000036907 denotes amino acid residues
T89 6530-6532 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T90 6536-6537 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T91 6760-6762 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T92 6869-6870 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T93 6993-6995 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T94 6993-6995 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T95 7415-7423 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T96 7546-7549 http://purl.obolibrary.org/obo/NCBITaxon_9397 denotes bat
T97 7559-7570 http://purl.obolibrary.org/obo/NCBITaxon_9397 denotes such as bat
T98 7587-7590 http://purl.obolibrary.org/obo/NCBITaxon_9397 denotes bat

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T1 1550-1552 Chemical denotes SL http://purl.obolibrary.org/obo/CHEBI_74815
T2 1767-1769 Chemical denotes SL http://purl.obolibrary.org/obo/CHEBI_74815
T3 1786-1788 Chemical denotes SL http://purl.obolibrary.org/obo/CHEBI_74815
T4 1837-1839 Chemical denotes SL http://purl.obolibrary.org/obo/CHEBI_74815
T5 2330-2337 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T6 2419-2421 Chemical denotes SL http://purl.obolibrary.org/obo/CHEBI_74815
T7 2436-2438 Chemical denotes SL http://purl.obolibrary.org/obo/CHEBI_74815
T8 2570-2577 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T9 2592-2594 Chemical denotes SP http://purl.obolibrary.org/obo/CHEBI_74820
T10 2603-2610 Chemical denotes peptide http://purl.obolibrary.org/obo/CHEBI_16670
T11 2666-2668 Chemical denotes FP http://purl.obolibrary.org/obo/CHEBI_74750
T12 2677-2684 Chemical denotes peptide http://purl.obolibrary.org/obo/CHEBI_16670
T13 2730-2732 Chemical denotes TM http://purl.obolibrary.org/obo/CHEBI_55460|http://purl.obolibrary.org/obo/CHEBI_74861
T15 2756-2758 Chemical denotes CP http://purl.obolibrary.org/obo/CHEBI_3380|http://purl.obolibrary.org/obo/CHEBI_73461
T17 2873-2883 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T18 3226-3238 Chemical denotes nucleic acid http://purl.obolibrary.org/obo/CHEBI_33696
T19 3234-3238 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T20 3814-3821 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T21 3870-3872 Chemical denotes SL http://purl.obolibrary.org/obo/CHEBI_74815
T22 3937-3939 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T23 4329-4331 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T24 4382-4389 Chemical denotes peptide http://purl.obolibrary.org/obo/CHEBI_16670
T25 4391-4393 Chemical denotes FP http://purl.obolibrary.org/obo/CHEBI_74750
T26 4476-4478 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T27 4525-4527 Chemical denotes FP http://purl.obolibrary.org/obo/CHEBI_74750
T28 4801-4808 Chemical denotes peptide http://purl.obolibrary.org/obo/CHEBI_16670
T29 4851-4858 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T30 4860-4864 Chemical denotes SC-1 http://purl.obolibrary.org/obo/CHEBI_136542
T31 4906-4913 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T32 5037-5044 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T33 5227-5238 Chemical denotes amino acids http://purl.obolibrary.org/obo/CHEBI_33709
T34 5227-5232 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T35 5233-5238 Chemical denotes acids http://purl.obolibrary.org/obo/CHEBI_37527
T36 5256-5260 Chemical denotes SC-1 http://purl.obolibrary.org/obo/CHEBI_136542
T37 5261-5268 Chemical denotes peptide http://purl.obolibrary.org/obo/CHEBI_16670
T38 5389-5398 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T39 5404-5411 Chemical denotes peptide http://purl.obolibrary.org/obo/CHEBI_16670
T40 5519-5521 Chemical denotes SL http://purl.obolibrary.org/obo/CHEBI_74815
T41 5543-5554 Chemical denotes application http://purl.obolibrary.org/obo/CHEBI_33232
T42 5562-5569 Chemical denotes peptide http://purl.obolibrary.org/obo/CHEBI_16670
T43 5607-5614 Chemical denotes peptide http://purl.obolibrary.org/obo/CHEBI_16670
T44 5805-5812 Chemical denotes peptide http://purl.obolibrary.org/obo/CHEBI_16670
T45 5863-5874 Chemical denotes application http://purl.obolibrary.org/obo/CHEBI_33232
T46 6214-6221 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T47 6262-6272 Chemical denotes amino acid http://purl.obolibrary.org/obo/CHEBI_33709
T48 6262-6267 Chemical denotes amino http://purl.obolibrary.org/obo/CHEBI_46882
T49 6268-6272 Chemical denotes acid http://purl.obolibrary.org/obo/CHEBI_37527
T50 6776-6783 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T51 6993-6995 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T52 7550-7552 Chemical denotes SL http://purl.obolibrary.org/obo/CHEBI_74815
T53 7571-7573 Chemical denotes SL http://purl.obolibrary.org/obo/CHEBI_74815
T54 7591-7593 Chemical denotes SL http://purl.obolibrary.org/obo/CHEBI_74815

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T2 36-45 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T3 1060-1069 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T4 3537-3546 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T1 3028-3049 http://purl.obolibrary.org/obo/GO_0001171 denotes reverse transcription
T2 3036-3049 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T3 3074-3095 http://purl.obolibrary.org/obo/GO_0001171 denotes reverse transcription
T4 3082-3095 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T5 3111-3132 http://purl.obolibrary.org/obo/GO_0001171 denotes reverse transcription
T6 3119-3132 http://purl.obolibrary.org/obo/GO_0006351 denotes transcription
T7 4988-4997 http://purl.obolibrary.org/obo/GO_0009058 denotes formation

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T5 0-342 Sentence denotes In December of 2019, an outbreak of pneumonia caused by an unknown aetiology occurred in Wuhan, China and most patients were linked to a single seafood market, which reportedly sold seafood and some live animals, including poultry, bats, marmots and other wild animals, suggesting that the pathogen may be transmitted from an animal to human.
T6 343-432 Sentence denotes The pathogen was soon identified to be a novel coronavirus, 2019-nCoV denoted by WHO [1].
T7 433-624 Sentence denotes On 19 January 2020, Wuhan Health Commission reported that a total 198 cases in the 25–89-year-old range were confirmed positive for 2019-nCoV, including 25 being discharged and 3 having died.
T8 625-857 Sentence denotes Among the 170 patients under treatment in hospitals, 126, 35, and 9 are in mild, severe, and critical condition, respectively (http://www.thatsmags.com/china/post/30618/new-coronavirus-spreads-to-over-130-in-china-death-toll-rises).
T9 858-972 Sentence denotes In addition, two patients in Thailand, one in Japan, and one in South Korea, were detected positive for 2019-nCoV.
T10 973-1285 Sentence denotes They did not visit the specific seafood market, but might have close contact with some pneumonia patients during their trip in Wuhan, raising the concern of limited human-to-human transmission of 2019-nCoV (http://www.thatsmags.com/china/post/30618/new-coronavirus-spreads-to-over-130-in-china-death-toll-rises).
T11 1286-1402 Sentence denotes Research scientists have released the full genomic sequence of 2019-nCoV, such as Wuhan-Hu-1 (GenBank, accession no.
T12 1403-1413 Sentence denotes MN908947).
T13 1414-1576 Sentence denotes The phylogenetic analysis revealed that the gene sequence of 2016-nCoV is 89% identical to that of bat SARS-like coronavirus ZXC21 (bat-SL-CoVZXC21, accession no.
T14 1577-1827 Sentence denotes MG772934.1) and ZC45 (MG772933.1), and 82% identical to that of SARS-CoV Tor2 (JX163927), suggesting that 2019-nCoV also belongs to betacoronavirus Lineage B, but has closer homology to bat-SL-CoVZC45 and bat-SL-CoVZXC21 than SARS-CoV [2] (Figure 1).
T15 1828-2038 Sentence denotes Both bat-SL-CoV ZC45 and ZXC21 were found in Chinese horseshoe bats (Rhinolopus sinicus) in Zhoushan city of Zhejiang Province, China between 2015 and 2017 [3], which can infect suckling rats and cause disease.
T16 2039-2265 Sentence denotes Given that there were some bats and live animals in the seafood market, 2019-nCoV may be originated from bats or live animals exposure to the materials contaminated with bat droppings in the seafood market or surrounding area.
T17 2266-2275 Sentence denotes Figure 1.
T18 2276-2591 Sentence denotes Analysis of the functional domains in 2019-nCoV spike protein and its gene. (A) Phylogenetic analysis of S gene of 2019-nCoV (Wuhan-Hu-1), bat-SL-CoVZXC21, bat-SL-CoVZXC45, SARS-CoV and other coronaviruses using Neighbor-Joining method. (B) The representative scheme of functional domains in S protein of 2019-nCoV.
T19 2592-2884 Sentence denotes SP, signal peptide; NTD, N-terminal domain; RBD, receptor-binding domain; FP, fusion peptide, HR1, heptad repeat 1; HR2, heptad repeat 2; TM, transmembrane domain; CP, cytoplasmic domain. (C) The target sites in 2019-nCoV S for development of vaccines, antibodies and fusion/entry inhibitors.
T20 2885-3285 Sentence denotes The rapid identification of this novel coronavirus is attributed to recent advances in the detection of respiratory virus infection, including reverse transcription PCR (RT-PCR), real-time reverse transcription PCR (rRT-PCR), reverse transcription loop-mediated isothermal amplification (RT-LAMP), and real-time RT-LAMP as well as multiplex nucleic acid amplification and microarray-based assays [4].
T21 3286-3458 Sentence denotes These methods are useful for detecting novel coronaviruses not only in humans, but also in animals for identification of animal reservoir or intermediate host of 2019-nCoV.
T22 3459-3789 Sentence denotes WHO recommended that if there is no clue about the putative pathogen from the pneumonia outbreak, a pan-coronavirus assay should be used for amplification followed by sequencing of the amplicon for characterization and confirmation (https://apps.who.int/iris/bitstream/handle/10665/330374/WHO-2019-nCoV-laboratory-2020.1-eng.pdf).
T23 3790-3984 Sentence denotes By aligning 2019-nCoV S protein sequence with those of SARS-CoV and several bat-SL-CoVs, we predicted that the cleavage site for generating S1 and S2 subunits is located at R694/S695 (Figure 1).
T24 3985-4187 Sentence denotes S1 subunit contains two functional domains, the N-terminal domain (NTD) and a receptor-binding domain (RBD), both of which are responsible for the binding of the virion to the receptor on the host cell.
T25 4188-4328 Sentence denotes They also contain several conformational neutralizing epitopes, serving as a target for developing neutralizing antibodies and vaccines [5].
T26 4329-4427 Sentence denotes S2 subunit contains three functional domains, fusion peptide (FP), and heptad repeat (HR) 1 and 2.
T27 4428-4688 Sentence denotes After binding of RBD in S1 to the receptor, the S2 subunit changes conformation by inserting the FP into the host cell membrane and association between HR1 and HR2 to form six-helical bundle (6-HB), resulting in the fusion between viral and cellular membranes.
T28 4689-4798 Sentence denotes The viral genetic materials enter into the host cell through the fusion pore for replication in the cell [5].
T29 4799-5103 Sentence denotes A peptide derived from the HR2 domain of SARS-CoV S protein (SC-1) can interact with HR1 region in viral S protein to form heterologous 6-HB, resulting in the inhibition of homologous 6-HB formation between HR1 and HR2 domains in viral S protein and thus blocking the viral fusion with the host cell [6].
T30 5104-5330 Sentence denotes Since 2019-nCoV S-HR2 sequence is 100% identical to that of SARS-CoV, while there are only a few mutations of non-critical amino acids in S-HR1 region, SC-1 peptide is expected to be also effective against 2019-nCoV infection.
T31 5331-5531 Sentence denotes We have recently designed and engineered a pan-CoV fusion inhibitor, EK1 peptide, which could inhibit infection of five human coronaviruses, including SARS-CoV and MERS-CoV, and three bat-SL-CoVs [7].
T32 5532-5768 Sentence denotes Intranasal application of EK1 peptide before or after viral challenge, EK1 peptide can protect human DPP4-transgenic mice from MERS-CoV infection, suggesting its potential prophylactic and therapeutic effect against 2019-nCoV infection.
T33 5769-5965 Sentence denotes Once confirmed, we will develop EK1 peptide as a t prophylactic or therapeutic for intranasal application to prevent or treat infection by 2019-nCoV and other emerging coronaviruses in the future.
T34 5966-6230 Sentence denotes The RBDs of SARS-CoV and MERS-CoV contain multiple conformation-dependent neutralizing epitopes that induce more potent neutralizing antibodies and protective efficacy against SARS-CoV and MERS-CoV infections, respectively, than other regions in S protein [5,8,9].
T35 6231-6493 Sentence denotes Modification of MERS-CoV S-RBD amino acid residues based on the structure design could improve its protection against MERS-CoV infection [9], suggesting that 2019-nCoV S-RBD or modified S-RBD of other coronavirus may be applied for developing 2019-nCoV vaccines.
T36 6494-6612 Sentence denotes Of course, the RBD-containing S and S1 of a coronavirus, e.g. 2019-nCoV, can also be used for vaccine development [8].
T37 6613-6816 Sentence denotes The recently developed SARS-CoV and MERS-CoV neutralizing monoclonal antibodies (mAbs) and nanobodies with protective efficacy are specific to the S1 subunit of S protein, particularly the RBD [5,89–10].
T38 6817-6925 Sentence denotes Therefore, the 2019-nCoV S-RBD is anticipated to be a key target for developing 2019-nCoV neutralizing mAbs.
T39 6926-7150 Sentence denotes The neutralizing mAbs targeting non-RBD regions, including NTD and S2 of SARS-CoV and/or MERS-CoV S could also be identified [5,8,11,12], although their neutralizing potency is generally lower than that of RBD-specific mAbs.
T40 7151-7275 Sentence denotes It may take several months or even years for researching and developing neutralizing antibodies against 2019-nCoV infection.
T41 7276-7452 Sentence denotes One of the rapid approaches is to evaluate the currently available SARS-CoV neutralizing antibodies with cross-neutralizing and protection activity against 2019-nCoV infection.
T42 7453-7668 Sentence denotes We have shown that SARS-CoV S-RBD-specific neutralizing mAbs and sera could cross-neutralize bat-SL-CoVs, such as bat-SL-CoV-W1V1 and bat-SL-CoV-SHC014 [13], suggesting that they may also cross-neutralize 2019-nCoV.
T43 7669-7807 Sentence denotes Once identified, these cross-neutralizing antibodies can be promptly developed for urgent prevention and treatment of 2019-nCoV infection.