PMC:7029759 / 38735-39156 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"1010","span":{"begin":12,"end":16},"obj":"Gene"},{"id":"1011","span":{"begin":288,"end":297},"obj":"Species"},{"id":"1012","span":{"begin":16,"end":19},"obj":"Chemical"},{"id":"1013","span":{"begin":120,"end":139},"obj":"Disease"}],"attributes":[{"id":"A1010","pred":"tao:has_database_id","subj":"1010","obj":"Gene:59272"},{"id":"A1011","pred":"tao:has_database_id","subj":"1011","obj":"Tax:2697049"},{"id":"A1013","pred":"tao:has_database_id","subj":"1013","obj":"MESH:C000657245"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"In summary, ACE2-Fc has the potential to be the neutralizing antibody that healthcare workers need to treat and prevent 2019-nCoV infection today and could play an important role in the cessation of the outbreak if manufacturing based on an available sequence starts soon. An alternative 2019-nCoV RBD-Fc fusion could also be pursued, if one desired the dual function of receptor blocking and vaccination in one molecule."}

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T624","span":{"begin":12,"end":16},"obj":"G_3;PG_10;PR:000003622"},{"id":"T623","span":{"begin":61,"end":69},"obj":"GO:0042571"},{"id":"T622","span":{"begin":120,"end":129},"obj":"SP_7"},{"id":"T621","span":{"begin":288,"end":297},"obj":"SP_7"},{"id":"T620","span":{"begin":412,"end":420},"obj":"CHEBI:36357;CHEBI:36357"}],"text":"In summary, ACE2-Fc has the potential to be the neutralizing antibody that healthcare workers need to treat and prevent 2019-nCoV infection today and could play an important role in the cessation of the outbreak if manufacturing based on an available sequence starts soon. An alternative 2019-nCoV RBD-Fc fusion could also be pursued, if one desired the dual function of receptor blocking and vaccination in one molecule."}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T237","span":{"begin":61,"end":69},"obj":"Body_part"}],"attributes":[{"id":"A237","pred":"fma_id","subj":"T237","obj":"http://purl.org/sig/ont/fma/fma62871"}],"text":"In summary, ACE2-Fc has the potential to be the neutralizing antibody that healthcare workers need to treat and prevent 2019-nCoV infection today and could play an important role in the cessation of the outbreak if manufacturing based on an available sequence starts soon. An alternative 2019-nCoV RBD-Fc fusion could also be pursued, if one desired the dual function of receptor blocking and vaccination in one molecule."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T130","span":{"begin":120,"end":139},"obj":"Disease"},{"id":"T131","span":{"begin":130,"end":139},"obj":"Disease"}],"attributes":[{"id":"A130","pred":"mondo_id","subj":"T130","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A131","pred":"mondo_id","subj":"T131","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"}],"text":"In summary, ACE2-Fc has the potential to be the neutralizing antibody that healthcare workers need to treat and prevent 2019-nCoV infection today and could play an important role in the cessation of the outbreak if manufacturing based on an available sequence starts soon. An alternative 2019-nCoV RBD-Fc fusion could also be pursued, if one desired the dual function of receptor blocking and vaccination in one molecule."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T405","span":{"begin":17,"end":19},"obj":"http://purl.obolibrary.org/obo/CLO_0052676"},{"id":"T406","span":{"begin":20,"end":23},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T407","span":{"begin":302,"end":304},"obj":"http://purl.obolibrary.org/obo/CLO_0052676"}],"text":"In summary, ACE2-Fc has the potential to be the neutralizing antibody that healthcare workers need to treat and prevent 2019-nCoV infection today and could play an important role in the cessation of the outbreak if manufacturing based on an available sequence starts soon. An alternative 2019-nCoV RBD-Fc fusion could also be pursued, if one desired the dual function of receptor blocking and vaccination in one molecule."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T167","span":{"begin":412,"end":420},"obj":"Chemical"}],"attributes":[{"id":"A167","pred":"chebi_id","subj":"T167","obj":"http://purl.obolibrary.org/obo/CHEBI_25367"}],"text":"In summary, ACE2-Fc has the potential to be the neutralizing antibody that healthcare workers need to treat and prevent 2019-nCoV infection today and could play an important role in the cessation of the outbreak if manufacturing based on an available sequence starts soon. An alternative 2019-nCoV RBD-Fc fusion could also be pursued, if one desired the dual function of receptor blocking and vaccination in one molecule."}

{"project":"LitCovid-sentences","denotations":[{"id":"T239","span":{"begin":0,"end":272},"obj":"Sentence"},{"id":"T240","span":{"begin":273,"end":421},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"In summary, ACE2-Fc has the potential to be the neutralizing antibody that healthcare workers need to treat and prevent 2019-nCoV infection today and could play an important role in the cessation of the outbreak if manufacturing based on an available sequence starts soon. An alternative 2019-nCoV RBD-Fc fusion could also be pursued, if one desired the dual function of receptor blocking and vaccination in one molecule."}