PMC:7029759 / 32457-32683 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"856","span":{"begin":65,"end":69},"obj":"Gene"},{"id":"865","span":{"begin":216,"end":217},"obj":"Gene"},{"id":"870","span":{"begin":206,"end":215},"obj":"Species"},{"id":"874","span":{"begin":197,"end":201},"obj":"Disease"}],"attributes":[{"id":"A856","pred":"tao:has_database_id","subj":"856","obj":"Gene:59272"},{"id":"A865","pred":"tao:has_database_id","subj":"865","obj":"Gene:43740568"},{"id":"A870","pred":"tao:has_database_id","subj":"870","obj":"Tax:2697049"},{"id":"A874","pred":"tao:has_database_id","subj":"874","obj":"MESH:D045169"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"If investigators are still concerned, critical amino acid(s) for ACE2 peptidase activity could be mutated to abolish the native function of this sequence, while retaining high affinity binding for SARS and 2019-nCoV S protein."}

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T425","span":{"begin":65,"end":69},"obj":"G_3;PG_10;PR:000003622"},{"id":"T424","span":{"begin":197,"end":201},"obj":"SP_10"},{"id":"T423","span":{"begin":206,"end":215},"obj":"SP_7"},{"id":"T422","span":{"begin":216,"end":225},"obj":"PG_1"}],"text":"If investigators are still concerned, critical amino acid(s) for ACE2 peptidase activity could be mutated to abolish the native function of this sequence, while retaining high affinity binding for SARS and 2019-nCoV S protein."}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T209","span":{"begin":47,"end":57},"obj":"Body_part"},{"id":"T210","span":{"begin":218,"end":225},"obj":"Body_part"}],"attributes":[{"id":"A209","pred":"fma_id","subj":"T209","obj":"http://purl.org/sig/ont/fma/fma82739"},{"id":"A210","pred":"fma_id","subj":"T210","obj":"http://purl.org/sig/ont/fma/fma67257"}],"text":"If investigators are still concerned, critical amino acid(s) for ACE2 peptidase activity could be mutated to abolish the native function of this sequence, while retaining high affinity binding for SARS and 2019-nCoV S protein."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T117","span":{"begin":197,"end":201},"obj":"Disease"}],"attributes":[{"id":"A117","pred":"mondo_id","subj":"T117","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"If investigators are still concerned, critical amino acid(s) for ACE2 peptidase activity could be mutated to abolish the native function of this sequence, while retaining high affinity binding for SARS and 2019-nCoV S protein."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T338","span":{"begin":80,"end":88},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"}],"text":"If investigators are still concerned, critical amino acid(s) for ACE2 peptidase activity could be mutated to abolish the native function of this sequence, while retaining high affinity binding for SARS and 2019-nCoV S protein."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T144","span":{"begin":47,"end":57},"obj":"Chemical"},{"id":"T145","span":{"begin":47,"end":52},"obj":"Chemical"},{"id":"T146","span":{"begin":53,"end":57},"obj":"Chemical"},{"id":"T147","span":{"begin":218,"end":225},"obj":"Chemical"}],"attributes":[{"id":"A144","pred":"chebi_id","subj":"T144","obj":"http://purl.obolibrary.org/obo/CHEBI_33709"},{"id":"A145","pred":"chebi_id","subj":"T145","obj":"http://purl.obolibrary.org/obo/CHEBI_46882"},{"id":"A146","pred":"chebi_id","subj":"T146","obj":"http://purl.obolibrary.org/obo/CHEBI_37527"},{"id":"A147","pred":"chebi_id","subj":"T147","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"}],"text":"If investigators are still concerned, critical amino acid(s) for ACE2 peptidase activity could be mutated to abolish the native function of this sequence, while retaining high affinity binding for SARS and 2019-nCoV S protein."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T20","span":{"begin":70,"end":88},"obj":"http://purl.obolibrary.org/obo/GO_0008233"}],"text":"If investigators are still concerned, critical amino acid(s) for ACE2 peptidase activity could be mutated to abolish the native function of this sequence, while retaining high affinity binding for SARS and 2019-nCoV S protein."}

{"project":"LitCovid-sentences","denotations":[{"id":"T203","span":{"begin":0,"end":226},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"If investigators are still concerned, critical amino acid(s) for ACE2 peptidase activity could be mutated to abolish the native function of this sequence, while retaining high affinity binding for SARS and 2019-nCoV S protein."}