PMC:7029610 / 4508-6036
Annnotations
{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7029610","sourcedb":"PMC","sourceid":"7029610","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7029610","text":"Caring for 2019-nCoV patients represents a substantial exposure risk for ICU staff because of the following reasons: highly contagious with multiple transmission route, high exposure dose, long daily contact hours, and ICU stay. The basic reproductive number was estimated to be 2.2 (95% CI, 1.4 to 3.9) [3], or as high as between 3.6 and 4.0 [4]. The 2019-nCoV is proved to be transmitted by respiratory droplets, contact, and fecal-oral, even transmission through the eye is possible [5, 6]. The higher viral load and aerosol-generating procedures, such as non-invasive ventilation, magnify the exposure and transmission risk [2, 7, 8]. Moreover, virus shedding can be prolonged and last for \u003e 3 weeks according to some literature and our unpublished data [2]. Healthcare providers and those in contact with infected patients should utilize contact, droplet, and airborne precautions with N95 respirator. Strict infection prevention and control practices have been implemented and audited in our units following the infection prevention and control plan published by China’s National Health Committee (CNHC). In addition, well-equipped fever clinic as triage station with trained staff knowing 2019-nCoV case definitions is established. For suspected 2019-nCoV infection, several key points are crucial procedures: recording a detailed history, standardizing pneumonia workup, obtaining lower respiratory tract specimens [2, 8], and implementing droplet isolation to break the transmission chain in the healthcare setting 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