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PMC:7029158 / 1748-5939 JSONTXT

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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T1 99-102 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T2 998-1001 Body_part denotes HIV http://purl.org/sig/ont/fma/fma278683
T3 1096-1106 Body_part denotes nucleotide http://purl.org/sig/ont/fma/fma82740
T4 1354-1357 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T5 2293-2297 Body_part denotes face http://purl.org/sig/ont/fma/fma24728
T6 3101-3105 Body_part denotes hand http://purl.org/sig/ont/fma/fma9712

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 2293-2297 Body_part denotes face http://purl.obolibrary.org/obo/UBERON_0001456
T2 3101-3105 Body_part denotes hand http://purl.obolibrary.org/obo/UBERON_0002398

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T7 391-401 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550
T8 496-529 Disease denotes Severe Acute Respiratory Syndrome http://purl.obolibrary.org/obo/MONDO_0005091
T9 532-536 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T10 1002-1006 Disease denotes AIDS http://purl.obolibrary.org/obo/MONDO_0012268
T11 1073-1075 Disease denotes GS http://purl.obolibrary.org/obo/MONDO_0005773
T12 1159-1164 Disease denotes Ebola http://purl.obolibrary.org/obo/MONDO_0005737
T13 1432-1441 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T14 2326-2330 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T15 3558-3572 Disease denotes infectiousness http://purl.obolibrary.org/obo/MONDO_0005550
T16 3605-3614 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T17 3636-3645 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T4 31-32 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T5 52-59 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T6 65-66 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T7 134-135 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T8 360-366 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humans
T9 538-543 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T10 624-629 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T11 1094-1095 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T12 1181-1188 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T13 1190-1193 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T14 1481-1488 http://purl.obolibrary.org/obo/PR_000018263 denotes peptide
T15 1560-1561 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T16 1590-1593 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T17 1686-1689 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T18 1743-1746 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T19 2043-2048 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T20 2049-2052 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T21 2216-2219 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T22 2293-2297 http://purl.obolibrary.org/obo/UBERON_0001456 denotes face
T23 2605-2610 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T24 2730-2731 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T25 3210-3214 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test
T26 3271-3283 http://purl.obolibrary.org/obo/OBI_0000245 denotes Organization
T27 3340-3341 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T28 3367-3368 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T29 3753-3756 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T30 3858-3861 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T31 4018-4021 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T32 4030-4031 http://purl.obolibrary.org/obo/CLO_0001020 denotes a

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T1 33-38 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T2 136-141 Chemical denotes crown http://purl.obolibrary.org/obo/CHEBI_37409
T3 872-877 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T4 904-923 Chemical denotes protease inhibitors http://purl.obolibrary.org/obo/CHEBI_37670|http://purl.obolibrary.org/obo/CHEBI_60258
T6 913-923 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T7 935-944 Chemical denotes Lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T8 1073-1075 Chemical denotes GS http://purl.obolibrary.org/obo/CHEBI_73516
T9 1096-1106 Chemical denotes nucleotide http://purl.obolibrary.org/obo/CHEBI_36976
T10 1120-1124 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T11 1278-1293 Chemical denotes pharmaceuticals http://purl.obolibrary.org/obo/CHEBI_52217
T12 1302-1322 Chemical denotes nucleoside analogues http://purl.obolibrary.org/obo/CHEBI_60783
T13 1302-1312 Chemical denotes nucleoside http://purl.obolibrary.org/obo/CHEBI_33838
T14 1324-1348 Chemical denotes neuraminidase inhibitors http://purl.obolibrary.org/obo/CHEBI_52425
T15 1338-1348 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T16 1368-1378 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T17 1449-1472 Chemical denotes anti-inflammatory drugs http://purl.obolibrary.org/obo/CHEBI_35472
T18 1467-1472 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T19 1481-1488 Chemical denotes peptide http://purl.obolibrary.org/obo/CHEBI_16670
T20 1520-1525 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T21 1549-1551 Chemical denotes Lu http://purl.obolibrary.org/obo/CHEBI_33382
T22 4012-4017 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T5 1354-1367 http://purl.obolibrary.org/obo/GO_0032774 denotes RNA synthesis
T6 1358-1367 http://purl.obolibrary.org/obo/GO_0009058 denotes synthesis

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T11 0-12 Sentence denotes Introduction
T12 13-172 Sentence denotes Coronaviruses are a group of enveloped viruses with a positive-sense, single-stranded RNA and viral particles resembling a crown – from which the name derives.
T13 173-324 Sentence denotes They belong to the order of Nidovirales, family of Coronaviridae, and subfamily of Orthocoronavirinae (Carlos, Dela Cruz, Cao, Pasnick, & Jamil, 2020).
T14 325-726 Sentence denotes They can affect mammals, including humans, causing generally mild infectious disorders, sporadically leading to severe outbreaks clusters, such as those generated by the “Severe Acute Respiratory Syndrome” (SARS) virus in 2003 in mainland China, and by the “Middle East Respiratory Syndrome” (MERS) virus in 2012 in the Kingdom of Saudi Arabia and in 2015 in South Korea (Gralinski & Menachery, 2020).
T15 727-855 Sentence denotes Currently, there exist no vaccines or anti-viral treatments officially approved for the prevention or management of the disease.
T16 856-1072 Sentence denotes Anti-retroviral drugs belonging to the class of protease inhibitors, including Lopinavir and Ritonavir, usually utilized for the treatment of HIV/AIDS patients, seem to exert anti-viral effects against coronaviruses.
T17 1073-1261 Sentence denotes GS-734 (Remdesivir), a nucleotide analogue pro-drug, originally developed against the Ebola and the Marburg viruses, has been recently suggested to be effective also against coronaviruses.
T18 1262-1379 Sentence denotes Other potential pharmaceuticals include nucleoside analogues, neuraminidase inhibitors, and RNA synthesis inhibitors.
T19 1380-1559 Sentence denotes Also, Umifenovir (Abidol), used for treating severe influenza cases, anti-inflammatory drugs and EK1 peptide have been proposed as possible drugs against coronaviruses (Lu, 2020).
T20 1560-2026 Sentence denotes A recent coronavirus outbreak has started since December 29th, 2019 in Wuhan, Hubei province, People’s Republic of China, and has progressively expanded to various parts of China and has reached as well other countries, including Japan, South Korea, Thailand, Vietnam, Malaysia, Singapore, Nepal, Cambodia, the Philippines, Russia, the United Arab Emirates, Australia, Canada, the United States of America and Europe (France, Germany, Italy, UK, Finland and Sweden).
T21 2027-2187 Sentence denotes So far, the new virus has infected more than 31,000 people and killed at least 636 of them (National Health Commission of the People’s Republic of China, 2020).
T22 2188-2383 Sentence denotes While considerable progress has been achieved with respect to seventeen years ago, when the world had to face, completely unprepared, the SARS pandemics, several issues still remain to cope with.
T23 2384-2747 Sentence denotes In order to respond swiftly and properly to the outbreak, public health decision- and policy-makers need timely and accurate epidemiological information, concerning, for example, how long it may take from exposure to the virus to illness/symptoms onset or which individuals, with specific characteristics or co-morbidities, are at higher risk of a poor prognosis.
T24 2748-2951 Sentence denotes However, many data are still lacking and available data may not be accurate or reliable and may contain substantial uncertainty, concerning, for instance, the precise timing and natural history of cases.
T25 2952-3087 Sentence denotes Simulating different scenarios with evolving knowledge and gradually improved data quality present significant challenges for modelers.
T26 3088-3236 Sentence denotes On the other hand, scenario analysis could help ruling out some (unrealistic or over optimistic) assumptions, enabling to test different hypotheses.
T27 3237-3458 Sentence denotes As recognized by the World Health Organization (WHO), mathematical models, especially those devised in a timely fashion, can play a key role in providing health decision- and policy-makers with evidence-based information.
T28 3459-3712 Sentence denotes Modeling can, indeed, better help understanding: i) how transmissible the disease is, ii) when the infectiousness is highest during the course of infection, iii) how severe the infection is, and iv) how effective interventions have been and ought to be.
T29 3713-3914 Sentence denotes The international community of modelers has accepted the challenge of designing mathematical models of coronavirus dynamics and transmission and has swiftly reacted to the current coronavirus outbreak.
T30 3915-3995 Sentence denotes Several models have been produced, resulting, sometimes, in different estimates.
T31 3996-4093 Sentence denotes Previously, our group has devised a deterministic compartmental (SEIR) model (Tang et al., 2020).
T32 4094-4191 Sentence denotes In the present article, we update this model, based on the latest available data and information.

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T1 3625-3645 Phenotype denotes severe the infection http://purl.obolibrary.org/obo/HP_0032169

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
25 360-366 Species denotes humans Tax:9606
23 13-26 Species denotes Coronaviruses Tax:11118
24 224-237 Species denotes Coronaviridae Tax:11118
26 532-543 Species denotes SARS) virus Tax:694009
27 618-629 Species denotes MERS) virus Tax:1335626
28 391-411 Disease denotes infectious disorders MESH:D003141
29 503-529 Disease denotes Acute Respiratory Syndrome MESH:D012120
44 1324-1337 Gene denotes neuraminidase Gene:4758
45 1007-1015 Species denotes patients Tax:9606
46 1058-1071 Species denotes coronaviruses Tax:11118
47 1159-1164 Species denotes Ebola Tax:1570291
48 1247-1260 Species denotes coronaviruses Tax:11118
49 1534-1547 Species denotes coronaviruses Tax:11118
50 935-944 Chemical denotes Lopinavir MESH:D061466
51 1073-1079 Chemical denotes GS-734 MESH:C015600
52 1081-1091 Chemical denotes Remdesivir MESH:C000606551
53 1302-1312 Chemical denotes nucleoside MESH:D009705
54 1386-1396 Chemical denotes Umifenovir MESH:C086979
55 1398-1404 Chemical denotes Abidol
56 998-1001 Disease denotes HIV MESH:D015658
57 1002-1006 Disease denotes AIDS MESH:D000163
62 1569-1580 Species denotes coronavirus Tax:11118
63 1654-1660 Species denotes People Tax:9606
64 2079-2085 Species denotes people Tax:9606
65 2053-2061 Disease denotes infected MESH:D007239
67 2326-2330 Disease denotes SARS MESH:D045169
70 3605-3614 Disease denotes infection MESH:D007239
71 3636-3645 Disease denotes infection MESH:D007239
74 3816-3827 Species denotes coronavirus Tax:11118
75 3893-3904 Species denotes coronavirus Tax:11118