PMC:7025476 / 20142-20921 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7025476","sourcedb":"PMC","sourceid":"7025476","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7025476","text":"The effect of exogenous melatonin or luzindole on NLRP3 inflammasome activation and endogenous melatonin synthesis. (A) Representative blots showing the protein expression of NLRP3, mature IL-1β, pro-IL-1β, and caspase1(p20) in lung homogenate. (B–D) Relative band densities of NLRP3 and caspase1(p20) were analyzed by normalizing to GAPDH, relative band densities of IL-1β was analyzed by normalizing to pro-IL-1β. (E,F) The levels of IL-1β, IL-18 in BALF were detected by ELISA. (G) Representative blots showing the levels of AANAT and ASMT in lung homogenate. (H,I) Relative band densities of AANAT and ASMT were analyzed by normalizing to GAPDH. (J,K) The level of 5-HT in BALF and melatonin in the lung homogenate were detected by ELISA. *p \u003c 0.05, **p \u003c 0.01, ***p \u003c 0.001.","tracks":[]}