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PMC:7019868 / 20805-22228 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
374 517-520 Species denotes pig Tax:9823
375 1105-1109 Species denotes PEDV Tax:28295
376 131-138 Chemical denotes iPEDVPT
377 143-150 Chemical denotes iPEDVPT
378 159-166 Chemical denotes iPEDVPT
379 172-179 Chemical denotes iPEDVPT
380 791-801 Chemical denotes iPEDVPT-P5
381 814-821 Chemical denotes iPEDVPT
382 836-843 Chemical denotes iPEDVPT
383 994-997 Chemical denotes DPI
384 1005-1008 Chemical denotes DPI
385 1034-1044 Chemical denotes iPEDVPT-P5
386 1057-1068 Chemical denotes iPEDVPT-P96
387 1069-1071 Chemical denotes 5S
388 1334-1344 Chemical denotes iPEDVPT-P5
389 1359-1370 Chemical denotes iPEDVPT-P96
390 1371-1373 Chemical denotes 5S
391 1381-1384 Chemical denotes DPI
392 1419-1422 Chemical denotes DPI
393 594-602 Disease denotes diarrhea MESH:D003967
394 902-910 Disease denotes diarrhea MESH:D003967
395 912-920 Disease denotes anorexia MESH:D000855
396 1118-1134 Disease denotes villous blunting MESH:D018253
397 1139-1146 Disease denotes atrophy MESH:D001284

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T104 43-47 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T105 580-583 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T106 753-757 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T107 1154-1161 Body_part denotes jejunum http://purl.org/sig/ont/fma/fma7207
T108 1194-1199 Body_part denotes ileum http://purl.org/sig/ont/fma/fma7208
T109 1229-1237 Body_part denotes duodenum http://purl.org/sig/ont/fma/fma7206

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T18 1154-1161 Body_part denotes jejunum http://purl.obolibrary.org/obo/UBERON_0002115
T19 1194-1199 Body_part denotes ileum http://purl.obolibrary.org/obo/UBERON_0002116
T20 1229-1237 Body_part denotes duodenum http://purl.obolibrary.org/obo/UBERON_0002114

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T23 594-602 Disease denotes diarrhea http://purl.obolibrary.org/obo/MONDO_0001673
T24 902-910 Disease denotes diarrhea http://purl.obolibrary.org/obo/MONDO_0001673

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T231 43-47 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T232 70-72 http://purl.obolibrary.org/obo/CLO_0001407 denotes 52
T233 114-117 http://purl.obolibrary.org/obo/CLO_0054060 denotes 102
T234 187-194 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T235 356-363 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T236 454-461 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T237 730-737 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T238 753-757 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T239 935-943 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T240 969-973 http://purl.obolibrary.org/obo/CLO_0001757 denotes at 1
T241 1154-1161 http://purl.obolibrary.org/obo/UBERON_0002115 denotes jejunum
T242 1170-1171 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T243 1194-1199 http://purl.obolibrary.org/obo/UBERON_0002116 denotes ileum

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T107 204-206 Chemical denotes PI http://purl.obolibrary.org/obo/CHEBI_28874|http://purl.obolibrary.org/obo/CHEBI_53806|http://purl.obolibrary.org/obo/CHEBI_61484|http://purl.obolibrary.org/obo/CHEBI_74790
T111 649-654 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T112 1345-1350 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T113 1374-1379 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T44 494-508 http://purl.obolibrary.org/obo/GO_0019076 denotes viral shedding
T45 954-968 http://purl.obolibrary.org/obo/GO_0019076 denotes viral shedding

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T151 0-286 Sentence denotes To evaluate the pathogenicity related to S gene replacement in PEDVPT 52 strain, we orally inoculated 2 mL of 5 × 102 TCID50/mL of iPEDVPT-P5, iPEDVPT-P5-96S, iPEDVPT-P96, iPEDVPT-P96-5S viruses and with PI medium in seven-day-old crossbred piglets assigned in the corresponding groups.
T152 287-413 Sentence denotes Parameters used to assess the pathogenicity of different recombinant viruses were summarized in Table 2 and shown in Figure 2.
T153 414-570 Sentence denotes The target sequences of the recombinant viruses at the time point of peak fecal viral shedding in each pig was confirmed identical to the original inoculum.
T154 571-693 Sentence denotes No viral RNA shedding, diarrhea or mortality was detected in the mock-treated group during the entire experimental course.
T155 694-999 Sentence denotes Piglets inoculated with recombinant viruses carrying the S gene derived from the highly virulent iPEDVPT-P5, namely the iPEDVPT-P5 itself and iPEDVPT-P96-5S, had an early onset of clinical symptoms including diarrhea, anorexia and decreased activity, and peak viral shedding at 1 d post-inoculation (DPI).
T156 1000-1266 Sentence denotes At 3 DPI, piglets inoculated with iPEDVPT-P5 (n = 3) and iPEDVPT-P96-5S (n = 3) both exhibited extensive PEDV-induced villous blunting and atrophy in the jejunum and, to a lesser extent, in the ileum; histological changes in the duodenum were not obvious (Figure 3).
T157 1267-1423 Sentence denotes Mortality rates of both groups were comparable, reaching 50% at 2 (iPEDVPT-P5 group) and 5 (iPEDVPT-P96-5S group) DPI and ultimately exceeded 80% by 10 DPI.

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T13 594-602 Phenotype denotes diarrhea http://purl.obolibrary.org/obo/HP_0002014
T14 902-910 Phenotype denotes diarrhea http://purl.obolibrary.org/obo/HP_0002014
T15 912-920 Phenotype denotes anorexia http://purl.obolibrary.org/obo/HP_0002039