PMC:7003341 / 71283-72907
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T306 | 191-194 | Body_part | denotes | MAP | http://purl.org/sig/ont/fma/fma67847 |
| T307 | 377-383 | Body_part | denotes | mental | http://purl.org/sig/ont/fma/fma264279 |
| T308 | 441-450 | Body_part | denotes | capillary | http://purl.org/sig/ont/fma/fma63194 |
| T309 | 1170-1183 | Body_part | denotes | noradrenaline | http://purl.org/sig/ont/fma/fma61799 |
| T310 | 1217-1222 | Body_part | denotes | blood | http://purl.org/sig/ont/fma/fma9670 |
| T311 | 1242-1245 | Body_part | denotes | MAP | http://purl.org/sig/ont/fma/fma67847 |
| T312 | 1415-1419 | Body_part | denotes | vein | http://purl.org/sig/ont/fma/fma50723 |
| T313 | 1434-1438 | Body_part | denotes | vein | http://purl.org/sig/ont/fma/fma50723 |
| T314 | 1476-1482 | Body_part | denotes | tissue | http://purl.org/sig/ont/fma/fma9637 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T211 | 441-450 | Body_part | denotes | capillary | http://purl.obolibrary.org/obo/UBERON_0001982 |
| T212 | 1217-1222 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
| T213 | 1415-1419 | Body_part | denotes | vein | http://purl.obolibrary.org/obo/UBERON_0001638 |
| T214 | 1434-1438 | Body_part | denotes | vein | http://purl.obolibrary.org/obo/UBERON_0001638 |
| T215 | 1476-1482 | Body_part | denotes | tissue | http://purl.obolibrary.org/obo/UBERON_0000479 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T199 | 33-42 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T200 | 515-524 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T495 | 172-180 | http://purl.obolibrary.org/obo/UBERON_0001637 | denotes | arterial |
| T496 | 172-180 | http://www.ebi.ac.uk/efo/EFO_0000814 | denotes | arterial |
| T497 | 498-499 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T498 | 741-742 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T499 | 975-976 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T500 | 1217-1222 | http://purl.obolibrary.org/obo/UBERON_0000178 | denotes | blood |
| T501 | 1217-1222 | http://www.ebi.ac.uk/efo/EFO_0000296 | denotes | blood |
| T502 | 1337-1338 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T503 | 1404-1419 | http://ihtsdo.org/snomedct/anatomy#421466002 | denotes | peripheral vein |
| T504 | 1434-1438 | http://purl.obolibrary.org/obo/UBERON_0001638 | denotes | vein |
| T505 | 1434-1438 | http://www.ebi.ac.uk/efo/EFO_0000816 | denotes | vein |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T117 | 132-137 | Chemical | denotes | drugs | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T118 | 191-194 | Chemical | denotes | MAP | http://purl.obolibrary.org/obo/CHEBI_6716 |
| T119 | 210-217 | Chemical | denotes | lactate | http://purl.obolibrary.org/obo/CHEBI_24996 |
| T120 | 284-291 | Chemical | denotes | lactate | http://purl.obolibrary.org/obo/CHEBI_24996 |
| T121 | 809-817 | Chemical | denotes | solution | http://purl.obolibrary.org/obo/CHEBI_75958 |
| T122 | 1170-1183 | Chemical | denotes | noradrenaline | http://purl.obolibrary.org/obo/CHEBI_33569 |
| T123 | 1242-1245 | Chemical | denotes | MAP | http://purl.obolibrary.org/obo/CHEBI_6716 |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T194 | 21-26 | Phenotype | denotes | shock | http://purl.obolibrary.org/obo/HP_0031273 |
| T195 | 253-258 | Phenotype | denotes | shock | http://purl.obolibrary.org/obo/HP_0031273 |
| T196 | 391-399 | Phenotype | denotes | oliguria | http://purl.obolibrary.org/obo/HP_0100520 |
| T197 | 573-578 | Phenotype | denotes | shock | http://purl.obolibrary.org/obo/HP_0031273 |
| T198 | 705-710 | Phenotype | denotes | shock | http://purl.obolibrary.org/obo/HP_0031273 |
| T199 | 1128-1133 | Phenotype | denotes | shock | http://purl.obolibrary.org/obo/HP_0031273 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T19 | 1483-1491 | http://purl.obolibrary.org/obo/GO_0070265 | denotes | necrosis |
| T20 | 1483-1491 | http://purl.obolibrary.org/obo/GO_0019835 | denotes | necrosis |
| T21 | 1483-1491 | http://purl.obolibrary.org/obo/GO_0008219 | denotes | necrosis |
| T22 | 1483-1491 | http://purl.obolibrary.org/obo/GO_0001906 | denotes | necrosis |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T557 | 0-27 | Sentence | denotes | Recognize the septic shock. |
| T558 | 28-280 | Sentence | denotes | When infection is suspected or confirmed, and on the basis of full fluid resuscitation, vasoconstrictor drugs are still needed to maintain mean arterial pressure (MAP) ≥65 mmHg with lactate ≥2 mmol/L, the existence of septic shock should be considered. |
| T559 | 281-543 | Sentence | denotes | If lactate cannot be monitored for some reasons, the following three manifestations (changes in mental state, oliguria, poor peripheral perfusion and prolonged capillary filling time) should be considered as signs of a combination of infection and hypoperfusion. |
| T560 | 544-675 | Sentence | denotes | In resuscitation from septic shock in adults, at least 30 ml/kg of isotonic crystalloid was considered for adults in the first 3 h. |
| T561 | 676-790 | Sentence | denotes | In resuscitation from septic shock in children, give 20 ml/kg as a rapid bolus and up to 40–60 ml/kg in first aid. |
| T562 | 791-851 | Sentence | denotes | Isosmotic crystal solution is recommended for resuscitation. |
| T563 | 852-945 | Sentence | denotes | Do not use hypotonic crystalloids, starches, or gelatins for resuscitation in the first hour. |
| T564 | 946-1082 | Sentence | denotes | Albumin may be considered as a resuscitation fluid, but this recommendation was based on low- quality evidence under certain conditions. |
| T565 | 1083-1204 | Sentence | denotes | Administer vasoconstrictor is suggested when shock persists after fluid resuscitation, noradrenaline as the first choice. |
| T566 | 1205-1305 | Sentence | denotes | The initial blood pressure target is MAP ≥65 mmHg in adults and age-appropriate targets in children. |
| T567 | 1306-1520 | Sentence | denotes | If it is not possible to place a central venous catheter, vasopressors can be infused through the peripheral vein through large vein and signs of extravasation and local tissue necrosis should be closely monitored. |
| T568 | 1521-1560 | Sentence | denotes | If extravasation occurs, stop infusion. |
| T569 | 1561-1624 | Sentence | denotes | Vasopressors can also be administered via intraosseous needles. |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 1299 | 210-217 | Chemical | denotes | lactate | MESH:D019344 |
| 1300 | 284-291 | Chemical | denotes | lactate | MESH:D019344 |
| 1301 | 14-26 | Disease | denotes | septic shock | MESH:D012772 |
| 1302 | 33-42 | Disease | denotes | infection | MESH:D007239 |
| 1303 | 246-258 | Disease | denotes | septic shock | MESH:D012772 |
| 1304 | 391-399 | Disease | denotes | oliguria | MESH:D009846 |
| 1305 | 515-524 | Disease | denotes | infection | MESH:D007239 |
| 1310 | 714-722 | Species | denotes | children | Tax:9606 |
| 1311 | 566-578 | Disease | denotes | septic shock | MESH:D012772 |
| 1312 | 611-631 | Disease | denotes | isotonic crystalloid | |
| 1313 | 698-710 | Disease | denotes | septic shock | MESH:D012772 |
| 1317 | 946-953 | Gene | denotes | Albumin | Gene:213 |
| 1318 | 887-895 | Chemical | denotes | starches | MESH:D013213 |
| 1319 | 863-885 | Disease | denotes | hypotonic crystalloids | MESH:D009123 |
| 1323 | 1296-1304 | Species | denotes | children | Tax:9606 |
| 1324 | 1170-1183 | Chemical | denotes | noradrenaline | MESH:D009638 |
| 1325 | 1128-1133 | Disease | denotes | shock | MESH:D012769 |
| 1327 | 1483-1491 | Disease | denotes | necrosis | MESH:D009336 |