PMC:7003341 / 29550-32876 JSONTXT

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    LitCovid-PD-FMA-UBERON

    {"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T35","span":{"begin":132,"end":137},"obj":"Body_part"},{"id":"T36","span":{"begin":1023,"end":1040},"obj":"Body_part"},{"id":"T37","span":{"begin":1035,"end":1040},"obj":"Body_part"},{"id":"T38","span":{"begin":1067,"end":1078},"obj":"Body_part"},{"id":"T39","span":{"begin":1108,"end":1119},"obj":"Body_part"},{"id":"T40","span":{"begin":1152,"end":1162},"obj":"Body_part"},{"id":"T41","span":{"begin":1204,"end":1211},"obj":"Body_part"},{"id":"T42","span":{"begin":1314,"end":1320},"obj":"Body_part"},{"id":"T43","span":{"begin":1591,"end":1597},"obj":"Body_part"},{"id":"T44","span":{"begin":1685,"end":1702},"obj":"Body_part"},{"id":"T45","span":{"begin":1697,"end":1702},"obj":"Body_part"},{"id":"T46","span":{"begin":1719,"end":1730},"obj":"Body_part"},{"id":"T47","span":{"begin":1760,"end":1771},"obj":"Body_part"},{"id":"T48","span":{"begin":1799,"end":1809},"obj":"Body_part"},{"id":"T49","span":{"begin":1850,"end":1857},"obj":"Body_part"},{"id":"T50","span":{"begin":1921,"end":1932},"obj":"Body_part"},{"id":"T51","span":{"begin":2034,"end":2049},"obj":"Body_part"},{"id":"T52","span":{"begin":2093,"end":2108},"obj":"Body_part"},{"id":"T53","span":{"begin":2182,"end":2198},"obj":"Body_part"},{"id":"T54","span":{"begin":2209,"end":2215},"obj":"Body_part"},{"id":"T55","span":{"begin":2219,"end":2234},"obj":"Body_part"},{"id":"T56","span":{"begin":2299,"end":2314},"obj":"Body_part"},{"id":"T57","span":{"begin":2378,"end":2383},"obj":"Body_part"},{"id":"T58","span":{"begin":2750,"end":2767},"obj":"Body_part"},{"id":"T59","span":{"begin":2762,"end":2767},"obj":"Body_part"},{"id":"T60","span":{"begin":2794,"end":2805},"obj":"Body_part"},{"id":"T61","span":{"begin":2832,"end":2842},"obj":"Body_part"},{"id":"T62","span":{"begin":2883,"end":2890},"obj":"Body_part"},{"id":"T63","span":{"begin":2950,"end":2955},"obj":"Body_part"},{"id":"T64","span":{"begin":3063,"end":3080},"obj":"Body_part"},{"id":"T65","span":{"begin":3145,"end":3161},"obj":"Body_part"},{"id":"T66","span":{"begin":3260,"end":3275},"obj":"Body_part"},{"id":"T67","span":{"begin":3321,"end":3326},"obj":"Body_part"}],"attributes":[{"id":"A35","pred":"fma_id","subj":"T35","obj":"http://purl.org/sig/ont/fma/fma68877"},{"id":"A36","pred":"fma_id","subj":"T36","obj":"http://purl.org/sig/ont/fma/fma62852"},{"id":"A37","pred":"fma_id","subj":"T37","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A38","pred":"fma_id","subj":"T38","obj":"http://purl.org/sig/ont/fma/fma62863"},{"id":"A39","pred":"fma_id","subj":"T39","obj":"http://purl.org/sig/ont/fma/fma62863"},{"id":"A40","pred":"fma_id","subj":"T40","obj":"http://purl.org/sig/ont/fma/fma62861"},{"id":"A41","pred":"fma_id","subj":"T41","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A42","pred":"fma_id","subj":"T42","obj":"http://purl.org/sig/ont/fma/fma45737"},{"id":"A43","pred":"fma_id","subj":"T43","obj":"http://purl.org/sig/ont/fma/fma32558"},{"id":"A44","pred":"fma_id","subj":"T44","obj":"http://purl.org/sig/ont/fma/fma62852"},{"id":"A45","pred":"fma_id","subj":"T45","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A46","pred":"fma_id","subj":"T46","obj":"http://purl.org/sig/ont/fma/fma62863"},{"id":"A47","pred":"fma_id","subj":"T47","obj":"http://purl.org/sig/ont/fma/fma62863"},{"id":"A48","pred":"fma_id","subj":"T48","obj":"http://purl.org/sig/ont/fma/fma62861"},{"id":"A49","pred":"fma_id","subj":"T49","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A50","pred":"fma_id","subj":"T50","obj":"http://purl.org/sig/ont/fma/fma62845"},{"id":"A51","pred":"fma_id","subj":"T51","obj":"http://purl.org/sig/ont/fma/fma7371"},{"id":"A52","pred":"fma_id","subj":"T52","obj":"http://purl.org/sig/ont/fma/fma7371"},{"id":"A53","pred":"fma_id","subj":"T53","obj":"http://purl.org/sig/ont/fma/fma7333"},{"id":"A54","pred":"fma_id","subj":"T54","obj":"http://purl.org/sig/ont/fma/fma54640"},{"id":"A55","pred":"fma_id","subj":"T55","obj":"http://purl.org/sig/ont/fma/fma7370"},{"id":"A56","pred":"fma_id","subj":"T56","obj":"http://purl.org/sig/ont/fma/fma7371"},{"id":"A57","pred":"fma_id","subj":"T57","obj":"http://purl.org/sig/ont/fma/fma68877"},{"id":"A58","pred":"fma_id","subj":"T58","obj":"http://purl.org/sig/ont/fma/fma62852"},{"id":"A59","pred":"fma_id","subj":"T59","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A60","pred":"fma_id","subj":"T60","obj":"http://purl.org/sig/ont/fma/fma62863"},{"id":"A61","pred":"fma_id","subj":"T61","obj":"http://purl.org/sig/ont/fma/fma62861"},{"id":"A62","pred":"fma_id","subj":"T62","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A63","pred":"fma_id","subj":"T63","obj":"http://purl.org/sig/ont/fma/fma7197"},{"id":"A64","pred":"fma_id","subj":"T64","obj":"http://purl.org/sig/ont/fma/fma7383"},{"id":"A65","pred":"fma_id","subj":"T65","obj":"http://purl.org/sig/ont/fma/fma7337"},{"id":"A66","pred":"fma_id","subj":"T66","obj":"http://purl.org/sig/ont/fma/fma7371"},{"id":"A67","pred":"fma_id","subj":"T67","obj":"http://purl.org/sig/ont/fma/fma9576"}],"text":"Typical CT/X-ray imaging manifestation, including\nMultiple, patchy, sub-segmental or segmental ground-glass density shadows in both lungs. They were classified as “paving stone-like” changes by fine-grid or small honeycomb-like thickening of interlobular septa. The thinner the CT scan layers, the clearer the ground-glass opacity and thickening of interlobular septa were displayed. A slightly high-density and ground-glass change with fuzzy edge in the fine-grid or small honeycomb-like thickening of interlobular septa were presented by the high-resolution computed tomography (HRCT), (Fig. 1: 45 cases, 54.2% in a total of 83 cases). The resolution of X-ray was worse lower than that of CT in the resolution, which was basically manifested as ground-glass opacities with fuzzy edge (Fig. 2: 9 cases, 10.8% in a total of 83 cases).\nFig. 1 Typical CT imaging manifestation (case 1). A 38 years old male with fever without obvious inducement (39.3 ℃), dry cough and shortness of breath for 3 days. Laboratory test: normal white blood cells (6.35 × 109/L), decreased lymphocytes percentage (4.1%), decreased lymphocytes count (0.31 × 109/L), decreased eosinophil count (0 × 109/L)), increased C-reaction protein (170.91 mg/L), increased procalcitonin (0.45 ng/ml). Imaging examination: multiple patches, grid-like lobule and thickening of interlobular septa, typical “paving stone-like” signs. a SL(Slice): 6 mm; b high-resolution computed tomography(HRCT). HRCT. high-resolution computed tomography\nFig. 2 Typical CT / X-ray imaging manifestation (case 2). A 51 years old male with general muscle ache and fatigue for 1 week, fever for 1 day (39.1 ℃), anemia. Laboratory test: normal white blood cells (9.24 × 109/L), lymphocytes percentage (5.1%), decreased lymphocytes (0.47 × 109/ L), decreased eosinophil count (0 × 109/L), increased C-reaction protein (170.91 mg/L), increased procalcitonin (0.45 ng/ml), increased erythrocyte sedimentation rate (48 mm/h). Imaging examination: a shows patchy shadows in the outer region of the left lower lobe, b shows large ground-glass opacity in the left lower lobe, and c shows subpleural patchy ground-glass opacity in posterior part of right upper lobe and lower tongue of left upper lobe, d shows large ground-glass opacity in the basal segment of the left lower lobe\n(2) Multiple, patchy or large patches of consolidation in both lungs, with a little grid-like or honeycomb-shaped interlobular septal thickening, especially in the middle and lower lobes (Fig. 3: 26 cases, 31.3% in a total of 83 cases). It was more common in the elderly or severe condition patients.\nFig. 3 Typical CT / X-ray imaging manifestation (case 3). A 65 years old male with fever for 4 days (38.7 ℃). Laboratory test: normal white blood cells (3.72 × 109/L), decreased lymphocytes (0.9 × 109/ L), decreased eosinophil count (0 × 109/L), increased C-reaction protein (53.0 mg/L), increased procalcitonin (0.10 ng/ml), reduced liver function, hypoproteinemia, and mild anemia. Imaging examination: a and b showed large consolidation in the right middle lobe, patchy consolidation in the posterior and basal segment of the right lower lobe, with air-bronchogram inside, c showed patchy consolidation in the outer and basal segment of the left lower lobe, and a small amount of effusion in the right chest"}

    LitCovid-PD-UBERON

    {"project":"LitCovid-PD-UBERON","denotations":[{"id":"T37","span":{"begin":1029,"end":1034},"obj":"Body_part"},{"id":"T38","span":{"begin":1314,"end":1320},"obj":"Body_part"},{"id":"T39","span":{"begin":1691,"end":1696},"obj":"Body_part"},{"id":"T40","span":{"begin":2045,"end":2049},"obj":"Body_part"},{"id":"T41","span":{"begin":2104,"end":2108},"obj":"Body_part"},{"id":"T42","span":{"begin":2194,"end":2198},"obj":"Body_part"},{"id":"T43","span":{"begin":2209,"end":2215},"obj":"Body_part"},{"id":"T44","span":{"begin":2230,"end":2234},"obj":"Body_part"},{"id":"T45","span":{"begin":2310,"end":2314},"obj":"Body_part"},{"id":"T46","span":{"begin":2756,"end":2761},"obj":"Body_part"},{"id":"T47","span":{"begin":2950,"end":2955},"obj":"Body_part"},{"id":"T48","span":{"begin":3076,"end":3080},"obj":"Body_part"},{"id":"T49","span":{"begin":3157,"end":3161},"obj":"Body_part"},{"id":"T50","span":{"begin":3271,"end":3275},"obj":"Body_part"},{"id":"T51","span":{"begin":3321,"end":3326},"obj":"Body_part"}],"attributes":[{"id":"A37","pred":"uberon_id","subj":"T37","obj":"http://purl.obolibrary.org/obo/UBERON_0000178"},{"id":"A38","pred":"uberon_id","subj":"T38","obj":"http://purl.obolibrary.org/obo/UBERON_0009911"},{"id":"A39","pred":"uberon_id","subj":"T39","obj":"http://purl.obolibrary.org/obo/UBERON_0000178"},{"id":"A40","pred":"uberon_id","subj":"T40","obj":"http://purl.obolibrary.org/obo/UBERON_3010752"},{"id":"A41","pred":"uberon_id","subj":"T41","obj":"http://purl.obolibrary.org/obo/UBERON_3010752"},{"id":"A42","pred":"uberon_id","subj":"T42","obj":"http://purl.obolibrary.org/obo/UBERON_3010752"},{"id":"A43","pred":"uberon_id","subj":"T43","obj":"http://purl.obolibrary.org/obo/UBERON_0001723"},{"id":"A44","pred":"uberon_id","subj":"T44","obj":"http://purl.obolibrary.org/obo/UBERON_3010752"},{"id":"A45","pred":"uberon_id","subj":"T45","obj":"http://purl.obolibrary.org/obo/UBERON_3010752"},{"id":"A46","pred":"uberon_id","subj":"T46","obj":"http://purl.obolibrary.org/obo/UBERON_0000178"},{"id":"A47","pred":"uberon_id","subj":"T47","obj":"http://purl.obolibrary.org/obo/UBERON_0002107"},{"id":"A48","pred":"uberon_id","subj":"T48","obj":"http://purl.obolibrary.org/obo/UBERON_3010752"},{"id":"A49","pred":"uberon_id","subj":"T49","obj":"http://purl.obolibrary.org/obo/UBERON_3010752"},{"id":"A50","pred":"uberon_id","subj":"T50","obj":"http://purl.obolibrary.org/obo/UBERON_3010752"},{"id":"A51","pred":"uberon_id","subj":"T51","obj":"http://purl.obolibrary.org/obo/UBERON_0001443"}],"text":"Typical CT/X-ray imaging manifestation, including\nMultiple, patchy, sub-segmental or segmental ground-glass density shadows in both lungs. They were classified as “paving stone-like” changes by fine-grid or small honeycomb-like thickening of interlobular septa. The thinner the CT scan layers, the clearer the ground-glass opacity and thickening of interlobular septa were displayed. A slightly high-density and ground-glass change with fuzzy edge in the fine-grid or small honeycomb-like thickening of interlobular septa were presented by the high-resolution computed tomography (HRCT), (Fig. 1: 45 cases, 54.2% in a total of 83 cases). The resolution of X-ray was worse lower than that of CT in the resolution, which was basically manifested as ground-glass opacities with fuzzy edge (Fig. 2: 9 cases, 10.8% in a total of 83 cases).\nFig. 1 Typical CT imaging manifestation (case 1). A 38 years old male with fever without obvious inducement (39.3 ℃), dry cough and shortness of breath for 3 days. Laboratory test: normal white blood cells (6.35 × 109/L), decreased lymphocytes percentage (4.1%), decreased lymphocytes count (0.31 × 109/L), decreased eosinophil count (0 × 109/L)), increased C-reaction protein (170.91 mg/L), increased procalcitonin (0.45 ng/ml). Imaging examination: multiple patches, grid-like lobule and thickening of interlobular septa, typical “paving stone-like” signs. a SL(Slice): 6 mm; b high-resolution computed tomography(HRCT). HRCT. high-resolution computed tomography\nFig. 2 Typical CT / X-ray imaging manifestation (case 2). A 51 years old male with general muscle ache and fatigue for 1 week, fever for 1 day (39.1 ℃), anemia. Laboratory test: normal white blood cells (9.24 × 109/L), lymphocytes percentage (5.1%), decreased lymphocytes (0.47 × 109/ L), decreased eosinophil count (0 × 109/L), increased C-reaction protein (170.91 mg/L), increased procalcitonin (0.45 ng/ml), increased erythrocyte sedimentation rate (48 mm/h). Imaging examination: a shows patchy shadows in the outer region of the left lower lobe, b shows large ground-glass opacity in the left lower lobe, and c shows subpleural patchy ground-glass opacity in posterior part of right upper lobe and lower tongue of left upper lobe, d shows large ground-glass opacity in the basal segment of the left lower lobe\n(2) Multiple, patchy or large patches of consolidation in both lungs, with a little grid-like or honeycomb-shaped interlobular septal thickening, especially in the middle and lower lobes (Fig. 3: 26 cases, 31.3% in a total of 83 cases). It was more common in the elderly or severe condition patients.\nFig. 3 Typical CT / X-ray imaging manifestation (case 3). A 65 years old male with fever for 4 days (38.7 ℃). Laboratory test: normal white blood cells (3.72 × 109/L), decreased lymphocytes (0.9 × 109/ L), decreased eosinophil count (0 × 109/L), increased C-reaction protein (53.0 mg/L), increased procalcitonin (0.10 ng/ml), reduced liver function, hypoproteinemia, and mild anemia. Imaging examination: a and b showed large consolidation in the right middle lobe, patchy consolidation in the posterior and basal segment of the right lower lobe, with air-bronchogram inside, c showed patchy consolidation in the outer and basal segment of the left lower lobe, and a small amount of effusion in the right chest"}

    LitCovid_AGAC

    {"project":"LitCovid_AGAC","denotations":[{"id":"p1042s9","span":{"begin":1139,"end":1148},"obj":"NegReg"},{"id":"p1042s10","span":{"begin":1140,"end":1147},"obj":"MPA"},{"id":"p1042s21","span":{"begin":1178,"end":1187},"obj":"PosReg"},{"id":"p1042s22","span":{"begin":1179,"end":1190},"obj":"MPA"},{"id":"p1042s35","span":{"begin":1220,"end":1229},"obj":"PosReg"},{"id":"p1042s36","span":{"begin":1222,"end":1235},"obj":"MPA"},{"id":"p1053s30","span":{"begin":1783,"end":1792},"obj":"NegReg"},{"id":"p1053s31","span":{"begin":1785,"end":1795},"obj":"CPA"},{"id":"p1053s41","span":{"begin":1820,"end":1829},"obj":"PosReg"},{"id":"p1053s42","span":{"begin":1821,"end":1822},"obj":"MPA"},{"id":"p1053s55","span":{"begin":1863,"end":1872},"obj":"PosReg"},{"id":"p1053s56","span":{"begin":1865,"end":1878},"obj":"MPA"},{"id":"p1053s66","span":{"begin":1899,"end":1908},"obj":"PosReg"},{"id":"p1053s67","span":{"begin":1900,"end":1911},"obj":"CPA"},{"id":"p1062s26","span":{"begin":2816,"end":2825},"obj":"NegReg"},{"id":"p1062s37","span":{"begin":2853,"end":2862},"obj":"PosReg"},{"id":"p1062s38","span":{"begin":2854,"end":2866},"obj":"MPA"},{"id":"p1062s41","span":{"begin":2859,"end":2866},"obj":"Protein"},{"id":"p1062s51","span":{"begin":2895,"end":2904},"obj":"PosReg"},{"id":"p1062s52","span":{"begin":2896,"end":2909},"obj":"MPA"},{"id":"p1062s62","span":{"begin":2930,"end":2937},"obj":"NegReg"}],"text":"Typical CT/X-ray imaging manifestation, including\nMultiple, patchy, sub-segmental or segmental ground-glass density shadows in both lungs. They were classified as “paving stone-like” changes by fine-grid or small honeycomb-like thickening of interlobular septa. The thinner the CT scan layers, the clearer the ground-glass opacity and thickening of interlobular septa were displayed. A slightly high-density and ground-glass change with fuzzy edge in the fine-grid or small honeycomb-like thickening of interlobular septa were presented by the high-resolution computed tomography (HRCT), (Fig. 1: 45 cases, 54.2% in a total of 83 cases). The resolution of X-ray was worse lower than that of CT in the resolution, which was basically manifested as ground-glass opacities with fuzzy edge (Fig. 2: 9 cases, 10.8% in a total of 83 cases).\nFig. 1 Typical CT imaging manifestation (case 1). A 38 years old male with fever without obvious inducement (39.3 ℃), dry cough and shortness of breath for 3 days. Laboratory test: normal white blood cells (6.35 × 109/L), decreased lymphocytes percentage (4.1%), decreased lymphocytes count (0.31 × 109/L), decreased eosinophil count (0 × 109/L)), increased C-reaction protein (170.91 mg/L), increased procalcitonin (0.45 ng/ml). Imaging examination: multiple patches, grid-like lobule and thickening of interlobular septa, typical “paving stone-like” signs. a SL(Slice): 6 mm; b high-resolution computed tomography(HRCT). HRCT. high-resolution computed tomography\nFig. 2 Typical CT / X-ray imaging manifestation (case 2). A 51 years old male with general muscle ache and fatigue for 1 week, fever for 1 day (39.1 ℃), anemia. Laboratory test: normal white blood cells (9.24 × 109/L), lymphocytes percentage (5.1%), decreased lymphocytes (0.47 × 109/ L), decreased eosinophil count (0 × 109/L), increased C-reaction protein (170.91 mg/L), increased procalcitonin (0.45 ng/ml), increased erythrocyte sedimentation rate (48 mm/h). Imaging examination: a shows patchy shadows in the outer region of the left lower lobe, b shows large ground-glass opacity in the left lower lobe, and c shows subpleural patchy ground-glass opacity in posterior part of right upper lobe and lower tongue of left upper lobe, d shows large ground-glass opacity in the basal segment of the left lower lobe\n(2) Multiple, patchy or large patches of consolidation in both lungs, with a little grid-like or honeycomb-shaped interlobular septal thickening, especially in the middle and lower lobes (Fig. 3: 26 cases, 31.3% in a total of 83 cases). It was more common in the elderly or severe condition patients.\nFig. 3 Typical CT / X-ray imaging manifestation (case 3). A 65 years old male with fever for 4 days (38.7 ℃). Laboratory test: normal white blood cells (3.72 × 109/L), decreased lymphocytes (0.9 × 109/ L), decreased eosinophil count (0 × 109/L), increased C-reaction protein (53.0 mg/L), increased procalcitonin (0.10 ng/ml), reduced liver function, hypoproteinemia, and mild anemia. Imaging examination: a and b showed large consolidation in the right middle lobe, patchy consolidation in the posterior and basal segment of the right lower lobe, with air-bronchogram inside, c showed patchy consolidation in the outer and basal segment of the left lower lobe, and a small amount of effusion in the right chest"}

    LitCovid-PD-MONDO

    {"project":"LitCovid-PD-MONDO","denotations":[{"id":"T78","span":{"begin":1653,"end":1659},"obj":"Disease"},{"id":"T79","span":{"begin":2992,"end":2998},"obj":"Disease"}],"attributes":[{"id":"A78","pred":"mondo_id","subj":"T78","obj":"http://purl.obolibrary.org/obo/MONDO_0002280"},{"id":"A79","pred":"mondo_id","subj":"T79","obj":"http://purl.obolibrary.org/obo/MONDO_0002280"}],"text":"Typical CT/X-ray imaging manifestation, including\nMultiple, patchy, sub-segmental or segmental ground-glass density shadows in both lungs. They were classified as “paving stone-like” changes by fine-grid or small honeycomb-like thickening of interlobular septa. The thinner the CT scan layers, the clearer the ground-glass opacity and thickening of interlobular septa were displayed. A slightly high-density and ground-glass change with fuzzy edge in the fine-grid or small honeycomb-like thickening of interlobular septa were presented by the high-resolution computed tomography (HRCT), (Fig. 1: 45 cases, 54.2% in a total of 83 cases). The resolution of X-ray was worse lower than that of CT in the resolution, which was basically manifested as ground-glass opacities with fuzzy edge (Fig. 2: 9 cases, 10.8% in a total of 83 cases).\nFig. 1 Typical CT imaging manifestation (case 1). A 38 years old male with fever without obvious inducement (39.3 ℃), dry cough and shortness of breath for 3 days. Laboratory test: normal white blood cells (6.35 × 109/L), decreased lymphocytes percentage (4.1%), decreased lymphocytes count (0.31 × 109/L), decreased eosinophil count (0 × 109/L)), increased C-reaction protein (170.91 mg/L), increased procalcitonin (0.45 ng/ml). Imaging examination: multiple patches, grid-like lobule and thickening of interlobular septa, typical “paving stone-like” signs. a SL(Slice): 6 mm; b high-resolution computed tomography(HRCT). HRCT. high-resolution computed tomography\nFig. 2 Typical CT / X-ray imaging manifestation (case 2). A 51 years old male with general muscle ache and fatigue for 1 week, fever for 1 day (39.1 ℃), anemia. Laboratory test: normal white blood cells (9.24 × 109/L), lymphocytes percentage (5.1%), decreased lymphocytes (0.47 × 109/ L), decreased eosinophil count (0 × 109/L), increased C-reaction protein (170.91 mg/L), increased procalcitonin (0.45 ng/ml), increased erythrocyte sedimentation rate (48 mm/h). Imaging examination: a shows patchy shadows in the outer region of the left lower lobe, b shows large ground-glass opacity in the left lower lobe, and c shows subpleural patchy ground-glass opacity in posterior part of right upper lobe and lower tongue of left upper lobe, d shows large ground-glass opacity in the basal segment of the left lower lobe\n(2) Multiple, patchy or large patches of consolidation in both lungs, with a little grid-like or honeycomb-shaped interlobular septal thickening, especially in the middle and lower lobes (Fig. 3: 26 cases, 31.3% in a total of 83 cases). It was more common in the elderly or severe condition patients.\nFig. 3 Typical CT / X-ray imaging manifestation (case 3). A 65 years old male with fever for 4 days (38.7 ℃). Laboratory test: normal white blood cells (3.72 × 109/L), decreased lymphocytes (0.9 × 109/ L), decreased eosinophil count (0 × 109/L), increased C-reaction protein (53.0 mg/L), increased procalcitonin (0.10 ng/ml), reduced liver function, hypoproteinemia, and mild anemia. Imaging examination: a and b showed large consolidation in the right middle lobe, patchy consolidation in the posterior and basal segment of the right lower lobe, with air-bronchogram inside, c showed patchy consolidation in the outer and basal segment of the left lower lobe, and a small amount of effusion in the right chest"}

    LitCovid-PD-CLO

    {"project":"LitCovid-PD-CLO","denotations":[{"id":"T127","span":{"begin":132,"end":137},"obj":"http://www.ebi.ac.uk/efo/EFO_0000934"},{"id":"T128","span":{"begin":384,"end":385},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T129","span":{"begin":597,"end":599},"obj":"http://purl.obolibrary.org/obo/CLO_0053799"},{"id":"T130","span":{"begin":616,"end":617},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T131","span":{"begin":813,"end":814},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T132","span":{"begin":885,"end":886},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T133","span":{"begin":900,"end":904},"obj":"http://purl.obolibrary.org/obo/UBERON_0003101"},{"id":"T134","span":{"begin":900,"end":904},"obj":"http://www.ebi.ac.uk/efo/EFO_0000970"},{"id":"T135","span":{"begin":1010,"end":1014},"obj":"http://purl.obolibrary.org/obo/UBERON_0000473"},{"id":"T136","span":{"begin":1029,"end":1040},"obj":"http://www.ebi.ac.uk/efo/EFO_0000296"},{"id":"T137","span":{"begin":1394,"end":1395},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T138","span":{"begin":1413,"end":1414},"obj":"http://purl.obolibrary.org/obo/CLO_0001021"},{"id":"T139","span":{"begin":1558,"end":1559},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T140","span":{"begin":1573,"end":1577},"obj":"http://purl.obolibrary.org/obo/UBERON_0003101"},{"id":"T141","span":{"begin":1573,"end":1577},"obj":"http://www.ebi.ac.uk/efo/EFO_0000970"},{"id":"T142","span":{"begin":1591,"end":1597},"obj":"http://purl.obolibrary.org/obo/UBERON_0001630"},{"id":"T143","span":{"begin":1591,"end":1597},"obj":"http://purl.obolibrary.org/obo/UBERON_0005090"},{"id":"T144","span":{"begin":1591,"end":1597},"obj":"http://www.ebi.ac.uk/efo/EFO_0000801"},{"id":"T145","span":{"begin":1591,"end":1597},"obj":"http://www.ebi.ac.uk/efo/EFO_0001949"},{"id":"T146","span":{"begin":1672,"end":1676},"obj":"http://purl.obolibrary.org/obo/UBERON_0000473"},{"id":"T147","span":{"begin":1691,"end":1702},"obj":"http://www.ebi.ac.uk/efo/EFO_0000296"},{"id":"T148","span":{"begin":1921,"end":1932},"obj":"http://purl.obolibrary.org/obo/CL_0000232"},{"id":"T149","span":{"begin":1953,"end":1955},"obj":"http://purl.obolibrary.org/obo/CLO_0001382"},{"id":"T150","span":{"begin":1984,"end":1985},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T151","span":{"begin":2051,"end":2052},"obj":"http://purl.obolibrary.org/obo/CLO_0001021"},{"id":"T152","span":{"begin":2164,"end":2173},"obj":"http://purl.obolibrary.org/obo/UBERON_0001353"},{"id":"T153","span":{"begin":2209,"end":2215},"obj":"http://purl.obolibrary.org/obo/UBERON_0001723"},{"id":"T154","span":{"begin":2378,"end":2383},"obj":"http://www.ebi.ac.uk/efo/EFO_0000934"},{"id":"T155","span":{"begin":2390,"end":2391},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T156","span":{"begin":2530,"end":2531},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T157","span":{"begin":2674,"end":2675},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T158","span":{"begin":2689,"end":2693},"obj":"http://purl.obolibrary.org/obo/UBERON_0003101"},{"id":"T159","span":{"begin":2689,"end":2693},"obj":"http://www.ebi.ac.uk/efo/EFO_0000970"},{"id":"T160","span":{"begin":2737,"end":2741},"obj":"http://purl.obolibrary.org/obo/UBERON_0000473"},{"id":"T161","span":{"begin":2756,"end":2767},"obj":"http://www.ebi.ac.uk/efo/EFO_0000296"},{"id":"T162","span":{"begin":2950,"end":2955},"obj":"http://purl.obolibrary.org/obo/UBERON_0002107"},{"id":"T163","span":{"begin":2950,"end":2955},"obj":"http://www.ebi.ac.uk/efo/EFO_0000887"},{"id":"T164","span":{"begin":3021,"end":3022},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T165","span":{"begin":3027,"end":3028},"obj":"http://purl.obolibrary.org/obo/CLO_0001021"},{"id":"T166","span":{"begin":3110,"end":3119},"obj":"http://purl.obolibrary.org/obo/UBERON_0001353"},{"id":"T167","span":{"begin":3281,"end":3282},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T168","span":{"begin":3321,"end":3326},"obj":"http://www.ebi.ac.uk/efo/EFO_0000965"}],"text":"Typical CT/X-ray imaging manifestation, including\nMultiple, patchy, sub-segmental or segmental ground-glass density shadows in both lungs. They were classified as “paving stone-like” changes by fine-grid or small honeycomb-like thickening of interlobular septa. The thinner the CT scan layers, the clearer the ground-glass opacity and thickening of interlobular septa were displayed. A slightly high-density and ground-glass change with fuzzy edge in the fine-grid or small honeycomb-like thickening of interlobular septa were presented by the high-resolution computed tomography (HRCT), (Fig. 1: 45 cases, 54.2% in a total of 83 cases). The resolution of X-ray was worse lower than that of CT in the resolution, which was basically manifested as ground-glass opacities with fuzzy edge (Fig. 2: 9 cases, 10.8% in a total of 83 cases).\nFig. 1 Typical CT imaging manifestation (case 1). A 38 years old male with fever without obvious inducement (39.3 ℃), dry cough and shortness of breath for 3 days. Laboratory test: normal white blood cells (6.35 × 109/L), decreased lymphocytes percentage (4.1%), decreased lymphocytes count (0.31 × 109/L), decreased eosinophil count (0 × 109/L)), increased C-reaction protein (170.91 mg/L), increased procalcitonin (0.45 ng/ml). Imaging examination: multiple patches, grid-like lobule and thickening of interlobular septa, typical “paving stone-like” signs. a SL(Slice): 6 mm; b high-resolution computed tomography(HRCT). HRCT. high-resolution computed tomography\nFig. 2 Typical CT / X-ray imaging manifestation (case 2). A 51 years old male with general muscle ache and fatigue for 1 week, fever for 1 day (39.1 ℃), anemia. Laboratory test: normal white blood cells (9.24 × 109/L), lymphocytes percentage (5.1%), decreased lymphocytes (0.47 × 109/ L), decreased eosinophil count (0 × 109/L), increased C-reaction protein (170.91 mg/L), increased procalcitonin (0.45 ng/ml), increased erythrocyte sedimentation rate (48 mm/h). Imaging examination: a shows patchy shadows in the outer region of the left lower lobe, b shows large ground-glass opacity in the left lower lobe, and c shows subpleural patchy ground-glass opacity in posterior part of right upper lobe and lower tongue of left upper lobe, d shows large ground-glass opacity in the basal segment of the left lower lobe\n(2) Multiple, patchy or large patches of consolidation in both lungs, with a little grid-like or honeycomb-shaped interlobular septal thickening, especially in the middle and lower lobes (Fig. 3: 26 cases, 31.3% in a total of 83 cases). It was more common in the elderly or severe condition patients.\nFig. 3 Typical CT / X-ray imaging manifestation (case 3). A 65 years old male with fever for 4 days (38.7 ℃). Laboratory test: normal white blood cells (3.72 × 109/L), decreased lymphocytes (0.9 × 109/ L), decreased eosinophil count (0 × 109/L), increased C-reaction protein (53.0 mg/L), increased procalcitonin (0.10 ng/ml), reduced liver function, hypoproteinemia, and mild anemia. Imaging examination: a and b showed large consolidation in the right middle lobe, patchy consolidation in the posterior and basal segment of the right lower lobe, with air-bronchogram inside, c showed patchy consolidation in the outer and basal segment of the left lower lobe, and a small amount of effusion in the right chest"}

    LitCovid-PD-CHEBI

    {"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T26","span":{"begin":900,"end":904},"obj":"Chemical"},{"id":"T27","span":{"begin":1204,"end":1211},"obj":"Chemical"},{"id":"T28","span":{"begin":1396,"end":1398},"obj":"Chemical"},{"id":"T29","span":{"begin":1573,"end":1577},"obj":"Chemical"},{"id":"T30","span":{"begin":1850,"end":1857},"obj":"Chemical"},{"id":"T31","span":{"begin":2689,"end":2693},"obj":"Chemical"},{"id":"T32","span":{"begin":2883,"end":2890},"obj":"Chemical"}],"attributes":[{"id":"A26","pred":"chebi_id","subj":"T26","obj":"http://purl.obolibrary.org/obo/CHEBI_30780"},{"id":"A27","pred":"chebi_id","subj":"T27","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A28","pred":"chebi_id","subj":"T28","obj":"http://purl.obolibrary.org/obo/CHEBI_74815"},{"id":"A29","pred":"chebi_id","subj":"T29","obj":"http://purl.obolibrary.org/obo/CHEBI_30780"},{"id":"A30","pred":"chebi_id","subj":"T30","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A31","pred":"chebi_id","subj":"T31","obj":"http://purl.obolibrary.org/obo/CHEBI_30780"},{"id":"A32","pred":"chebi_id","subj":"T32","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"}],"text":"Typical CT/X-ray imaging manifestation, including\nMultiple, patchy, sub-segmental or segmental ground-glass density shadows in both lungs. They were classified as “paving stone-like” changes by fine-grid or small honeycomb-like thickening of interlobular septa. The thinner the CT scan layers, the clearer the ground-glass opacity and thickening of interlobular septa were displayed. A slightly high-density and ground-glass change with fuzzy edge in the fine-grid or small honeycomb-like thickening of interlobular septa were presented by the high-resolution computed tomography (HRCT), (Fig. 1: 45 cases, 54.2% in a total of 83 cases). The resolution of X-ray was worse lower than that of CT in the resolution, which was basically manifested as ground-glass opacities with fuzzy edge (Fig. 2: 9 cases, 10.8% in a total of 83 cases).\nFig. 1 Typical CT imaging manifestation (case 1). A 38 years old male with fever without obvious inducement (39.3 ℃), dry cough and shortness of breath for 3 days. Laboratory test: normal white blood cells (6.35 × 109/L), decreased lymphocytes percentage (4.1%), decreased lymphocytes count (0.31 × 109/L), decreased eosinophil count (0 × 109/L)), increased C-reaction protein (170.91 mg/L), increased procalcitonin (0.45 ng/ml). Imaging examination: multiple patches, grid-like lobule and thickening of interlobular septa, typical “paving stone-like” signs. a SL(Slice): 6 mm; b high-resolution computed tomography(HRCT). HRCT. high-resolution computed tomography\nFig. 2 Typical CT / X-ray imaging manifestation (case 2). A 51 years old male with general muscle ache and fatigue for 1 week, fever for 1 day (39.1 ℃), anemia. Laboratory test: normal white blood cells (9.24 × 109/L), lymphocytes percentage (5.1%), decreased lymphocytes (0.47 × 109/ L), decreased eosinophil count (0 × 109/L), increased C-reaction protein (170.91 mg/L), increased procalcitonin (0.45 ng/ml), increased erythrocyte sedimentation rate (48 mm/h). Imaging examination: a shows patchy shadows in the outer region of the left lower lobe, b shows large ground-glass opacity in the left lower lobe, and c shows subpleural patchy ground-glass opacity in posterior part of right upper lobe and lower tongue of left upper lobe, d shows large ground-glass opacity in the basal segment of the left lower lobe\n(2) Multiple, patchy or large patches of consolidation in both lungs, with a little grid-like or honeycomb-shaped interlobular septal thickening, especially in the middle and lower lobes (Fig. 3: 26 cases, 31.3% in a total of 83 cases). It was more common in the elderly or severe condition patients.\nFig. 3 Typical CT / X-ray imaging manifestation (case 3). A 65 years old male with fever for 4 days (38.7 ℃). Laboratory test: normal white blood cells (3.72 × 109/L), decreased lymphocytes (0.9 × 109/ L), decreased eosinophil count (0 × 109/L), increased C-reaction protein (53.0 mg/L), increased procalcitonin (0.10 ng/ml), reduced liver function, hypoproteinemia, and mild anemia. Imaging examination: a and b showed large consolidation in the right middle lobe, patchy consolidation in the posterior and basal segment of the right lower lobe, with air-bronchogram inside, c showed patchy consolidation in the outer and basal segment of the left lower lobe, and a small amount of effusion in the right chest"}

    LitCovid-PD-HP

    {"project":"LitCovid-PD-HP","denotations":[{"id":"T52","span":{"begin":910,"end":915},"obj":"Phenotype"},{"id":"T53","span":{"begin":953,"end":962},"obj":"Phenotype"},{"id":"T54","span":{"begin":967,"end":986},"obj":"Phenotype"},{"id":"T55","span":{"begin":1142,"end":1168},"obj":"Phenotype"},{"id":"T56","span":{"begin":1591,"end":1602},"obj":"Phenotype"},{"id":"T57","span":{"begin":1607,"end":1614},"obj":"Phenotype"},{"id":"T58","span":{"begin":1627,"end":1632},"obj":"Phenotype"},{"id":"T59","span":{"begin":1653,"end":1659},"obj":"Phenotype"},{"id":"T60","span":{"begin":1789,"end":1815},"obj":"Phenotype"},{"id":"T61","span":{"begin":1911,"end":1951},"obj":"Phenotype"},{"id":"T62","span":{"begin":2699,"end":2704},"obj":"Phenotype"},{"id":"T63","span":{"begin":2822,"end":2848},"obj":"Phenotype"},{"id":"T64","span":{"begin":2966,"end":2981},"obj":"Phenotype"},{"id":"T65","span":{"begin":2992,"end":2998},"obj":"Phenotype"}],"attributes":[{"id":"A52","pred":"hp_id","subj":"T52","obj":"http://purl.obolibrary.org/obo/HP_0001945"},{"id":"A53","pred":"hp_id","subj":"T53","obj":"http://purl.obolibrary.org/obo/HP_0031246"},{"id":"A54","pred":"hp_id","subj":"T54","obj":"http://purl.obolibrary.org/obo/HP_0002098"},{"id":"A55","pred":"hp_id","subj":"T55","obj":"http://purl.obolibrary.org/obo/HP_0031891"},{"id":"A56","pred":"hp_id","subj":"T56","obj":"http://purl.obolibrary.org/obo/HP_0003326"},{"id":"A57","pred":"hp_id","subj":"T57","obj":"http://purl.obolibrary.org/obo/HP_0012378"},{"id":"A58","pred":"hp_id","subj":"T58","obj":"http://purl.obolibrary.org/obo/HP_0001945"},{"id":"A59","pred":"hp_id","subj":"T59","obj":"http://purl.obolibrary.org/obo/HP_0001903"},{"id":"A60","pred":"hp_id","subj":"T60","obj":"http://purl.obolibrary.org/obo/HP_0031891"},{"id":"A61","pred":"hp_id","subj":"T61","obj":"http://purl.obolibrary.org/obo/HP_0003565"},{"id":"A62","pred":"hp_id","subj":"T62","obj":"http://purl.obolibrary.org/obo/HP_0001945"},{"id":"A63","pred":"hp_id","subj":"T63","obj":"http://purl.obolibrary.org/obo/HP_0031891"},{"id":"A64","pred":"hp_id","subj":"T64","obj":"http://purl.obolibrary.org/obo/HP_0003075"},{"id":"A65","pred":"hp_id","subj":"T65","obj":"http://purl.obolibrary.org/obo/HP_0001903"}],"text":"Typical CT/X-ray imaging manifestation, including\nMultiple, patchy, sub-segmental or segmental ground-glass density shadows in both lungs. They were classified as “paving stone-like” changes by fine-grid or small honeycomb-like thickening of interlobular septa. The thinner the CT scan layers, the clearer the ground-glass opacity and thickening of interlobular septa were displayed. A slightly high-density and ground-glass change with fuzzy edge in the fine-grid or small honeycomb-like thickening of interlobular septa were presented by the high-resolution computed tomography (HRCT), (Fig. 1: 45 cases, 54.2% in a total of 83 cases). The resolution of X-ray was worse lower than that of CT in the resolution, which was basically manifested as ground-glass opacities with fuzzy edge (Fig. 2: 9 cases, 10.8% in a total of 83 cases).\nFig. 1 Typical CT imaging manifestation (case 1). A 38 years old male with fever without obvious inducement (39.3 ℃), dry cough and shortness of breath for 3 days. Laboratory test: normal white blood cells (6.35 × 109/L), decreased lymphocytes percentage (4.1%), decreased lymphocytes count (0.31 × 109/L), decreased eosinophil count (0 × 109/L)), increased C-reaction protein (170.91 mg/L), increased procalcitonin (0.45 ng/ml). Imaging examination: multiple patches, grid-like lobule and thickening of interlobular septa, typical “paving stone-like” signs. a SL(Slice): 6 mm; b high-resolution computed tomography(HRCT). HRCT. high-resolution computed tomography\nFig. 2 Typical CT / X-ray imaging manifestation (case 2). A 51 years old male with general muscle ache and fatigue for 1 week, fever for 1 day (39.1 ℃), anemia. Laboratory test: normal white blood cells (9.24 × 109/L), lymphocytes percentage (5.1%), decreased lymphocytes (0.47 × 109/ L), decreased eosinophil count (0 × 109/L), increased C-reaction protein (170.91 mg/L), increased procalcitonin (0.45 ng/ml), increased erythrocyte sedimentation rate (48 mm/h). Imaging examination: a shows patchy shadows in the outer region of the left lower lobe, b shows large ground-glass opacity in the left lower lobe, and c shows subpleural patchy ground-glass opacity in posterior part of right upper lobe and lower tongue of left upper lobe, d shows large ground-glass opacity in the basal segment of the left lower lobe\n(2) Multiple, patchy or large patches of consolidation in both lungs, with a little grid-like or honeycomb-shaped interlobular septal thickening, especially in the middle and lower lobes (Fig. 3: 26 cases, 31.3% in a total of 83 cases). It was more common in the elderly or severe condition patients.\nFig. 3 Typical CT / X-ray imaging manifestation (case 3). A 65 years old male with fever for 4 days (38.7 ℃). Laboratory test: normal white blood cells (3.72 × 109/L), decreased lymphocytes (0.9 × 109/ L), decreased eosinophil count (0 × 109/L), increased C-reaction protein (53.0 mg/L), increased procalcitonin (0.10 ng/ml), reduced liver function, hypoproteinemia, and mild anemia. Imaging examination: a and b showed large consolidation in the right middle lobe, patchy consolidation in the posterior and basal segment of the right lower lobe, with air-bronchogram inside, c showed patchy consolidation in the outer and basal segment of the left lower lobe, and a small amount of effusion in the right chest"}

    LitCovid-sentences

    {"project":"LitCovid-sentences","denotations":[{"id":"T247","span":{"begin":0,"end":49},"obj":"Sentence"},{"id":"T248","span":{"begin":50,"end":138},"obj":"Sentence"},{"id":"T249","span":{"begin":139,"end":261},"obj":"Sentence"},{"id":"T250","span":{"begin":262,"end":383},"obj":"Sentence"},{"id":"T251","span":{"begin":384,"end":596},"obj":"Sentence"},{"id":"T252","span":{"begin":597,"end":637},"obj":"Sentence"},{"id":"T253","span":{"begin":638,"end":794},"obj":"Sentence"},{"id":"T254","span":{"begin":795,"end":834},"obj":"Sentence"},{"id":"T255","span":{"begin":835,"end":884},"obj":"Sentence"},{"id":"T256","span":{"begin":885,"end":998},"obj":"Sentence"},{"id":"T257","span":{"begin":999,"end":1264},"obj":"Sentence"},{"id":"T258","span":{"begin":1265,"end":1406},"obj":"Sentence"},{"id":"T259","span":{"begin":1407,"end":1457},"obj":"Sentence"},{"id":"T260","span":{"begin":1458,"end":1499},"obj":"Sentence"},{"id":"T261","span":{"begin":1500,"end":1557},"obj":"Sentence"},{"id":"T262","span":{"begin":1558,"end":1660},"obj":"Sentence"},{"id":"T263","span":{"begin":1661,"end":1962},"obj":"Sentence"},{"id":"T264","span":{"begin":1963,"end":2314},"obj":"Sentence"},{"id":"T265","span":{"begin":2315,"end":2510},"obj":"Sentence"},{"id":"T266","span":{"begin":2511,"end":2551},"obj":"Sentence"},{"id":"T267","span":{"begin":2552,"end":2615},"obj":"Sentence"},{"id":"T268","span":{"begin":2616,"end":2673},"obj":"Sentence"},{"id":"T269","span":{"begin":2674,"end":2725},"obj":"Sentence"},{"id":"T270","span":{"begin":2726,"end":2999},"obj":"Sentence"},{"id":"T271","span":{"begin":3000,"end":3326},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Typical CT/X-ray imaging manifestation, including\nMultiple, patchy, sub-segmental or segmental ground-glass density shadows in both lungs. They were classified as “paving stone-like” changes by fine-grid or small honeycomb-like thickening of interlobular septa. The thinner the CT scan layers, the clearer the ground-glass opacity and thickening of interlobular septa were displayed. A slightly high-density and ground-glass change with fuzzy edge in the fine-grid or small honeycomb-like thickening of interlobular septa were presented by the high-resolution computed tomography (HRCT), (Fig. 1: 45 cases, 54.2% in a total of 83 cases). The resolution of X-ray was worse lower than that of CT in the resolution, which was basically manifested as ground-glass opacities with fuzzy edge (Fig. 2: 9 cases, 10.8% in a total of 83 cases).\nFig. 1 Typical CT imaging manifestation (case 1). A 38 years old male with fever without obvious inducement (39.3 ℃), dry cough and shortness of breath for 3 days. Laboratory test: normal white blood cells (6.35 × 109/L), decreased lymphocytes percentage (4.1%), decreased lymphocytes count (0.31 × 109/L), decreased eosinophil count (0 × 109/L)), increased C-reaction protein (170.91 mg/L), increased procalcitonin (0.45 ng/ml). Imaging examination: multiple patches, grid-like lobule and thickening of interlobular septa, typical “paving stone-like” signs. a SL(Slice): 6 mm; b high-resolution computed tomography(HRCT). HRCT. high-resolution computed tomography\nFig. 2 Typical CT / X-ray imaging manifestation (case 2). A 51 years old male with general muscle ache and fatigue for 1 week, fever for 1 day (39.1 ℃), anemia. Laboratory test: normal white blood cells (9.24 × 109/L), lymphocytes percentage (5.1%), decreased lymphocytes (0.47 × 109/ L), decreased eosinophil count (0 × 109/L), increased C-reaction protein (170.91 mg/L), increased procalcitonin (0.45 ng/ml), increased erythrocyte sedimentation rate (48 mm/h). Imaging examination: a shows patchy shadows in the outer region of the left lower lobe, b shows large ground-glass opacity in the left lower lobe, and c shows subpleural patchy ground-glass opacity in posterior part of right upper lobe and lower tongue of left upper lobe, d shows large ground-glass opacity in the basal segment of the left lower lobe\n(2) Multiple, patchy or large patches of consolidation in both lungs, with a little grid-like or honeycomb-shaped interlobular septal thickening, especially in the middle and lower lobes (Fig. 3: 26 cases, 31.3% in a total of 83 cases). It was more common in the elderly or severe condition patients.\nFig. 3 Typical CT / X-ray imaging manifestation (case 3). A 65 years old male with fever for 4 days (38.7 ℃). Laboratory test: normal white blood cells (3.72 × 109/L), decreased lymphocytes (0.9 × 109/ L), decreased eosinophil count (0 × 109/L), increased C-reaction protein (53.0 mg/L), increased procalcitonin (0.10 ng/ml), reduced liver function, hypoproteinemia, and mild anemia. Imaging examination: a and b showed large consolidation in the right middle lobe, patchy consolidation in the posterior and basal segment of the right lower lobe, with air-bronchogram inside, c showed patchy consolidation in the outer and basal segment of the left lower lobe, and a small amount of effusion in the right chest"}

    LitCovid-PubTator

    {"project":"LitCovid-PubTator","denotations":[{"id":"462","span":{"begin":213,"end":222},"obj":"Species"},{"id":"463","span":{"begin":474,"end":483},"obj":"Species"},{"id":"467","span":{"begin":910,"end":915},"obj":"Disease"},{"id":"468","span":{"begin":953,"end":962},"obj":"Disease"},{"id":"469","span":{"begin":967,"end":986},"obj":"Disease"},{"id":"474","span":{"begin":1591,"end":1602},"obj":"Disease"},{"id":"475","span":{"begin":1607,"end":1614},"obj":"Disease"},{"id":"476","span":{"begin":1627,"end":1632},"obj":"Disease"},{"id":"477","span":{"begin":1653,"end":1659},"obj":"Disease"},{"id":"480","span":{"begin":2412,"end":2421},"obj":"Species"},{"id":"481","span":{"begin":2606,"end":2614},"obj":"Species"},{"id":"486","span":{"begin":2699,"end":2704},"obj":"Disease"},{"id":"487","span":{"begin":2966,"end":2981},"obj":"Disease"},{"id":"488","span":{"begin":2992,"end":2998},"obj":"Disease"},{"id":"489","span":{"begin":3299,"end":3307},"obj":"Disease"}],"attributes":[{"id":"A462","pred":"tao:has_database_id","subj":"462","obj":"Tax:119431"},{"id":"A463","pred":"tao:has_database_id","subj":"463","obj":"Tax:119431"},{"id":"A467","pred":"tao:has_database_id","subj":"467","obj":"MESH:D005334"},{"id":"A468","pred":"tao:has_database_id","subj":"468","obj":"MESH:D003371"},{"id":"A469","pred":"tao:has_database_id","subj":"469","obj":"MESH:D004417"},{"id":"A474","pred":"tao:has_database_id","subj":"474","obj":"MESH:D063806"},{"id":"A475","pred":"tao:has_database_id","subj":"475","obj":"MESH:D005221"},{"id":"A476","pred":"tao:has_database_id","subj":"476","obj":"MESH:D005334"},{"id":"A477","pred":"tao:has_database_id","subj":"477","obj":"MESH:D000740"},{"id":"A480","pred":"tao:has_database_id","subj":"480","obj":"Tax:119431"},{"id":"A481","pred":"tao:has_database_id","subj":"481","obj":"Tax:9606"},{"id":"A486","pred":"tao:has_database_id","subj":"486","obj":"MESH:D005334"},{"id":"A487","pred":"tao:has_database_id","subj":"487","obj":"MESH:D007019"},{"id":"A488","pred":"tao:has_database_id","subj":"488","obj":"MESH:D000740"},{"id":"A489","pred":"tao:has_database_id","subj":"489","obj":"MESH:D010996"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Typical CT/X-ray imaging manifestation, including\nMultiple, patchy, sub-segmental or segmental ground-glass density shadows in both lungs. They were classified as “paving stone-like” changes by fine-grid or small honeycomb-like thickening of interlobular septa. The thinner the CT scan layers, the clearer the ground-glass opacity and thickening of interlobular septa were displayed. A slightly high-density and ground-glass change with fuzzy edge in the fine-grid or small honeycomb-like thickening of interlobular septa were presented by the high-resolution computed tomography (HRCT), (Fig. 1: 45 cases, 54.2% in a total of 83 cases). The resolution of X-ray was worse lower than that of CT in the resolution, which was basically manifested as ground-glass opacities with fuzzy edge (Fig. 2: 9 cases, 10.8% in a total of 83 cases).\nFig. 1 Typical CT imaging manifestation (case 1). A 38 years old male with fever without obvious inducement (39.3 ℃), dry cough and shortness of breath for 3 days. Laboratory test: normal white blood cells (6.35 × 109/L), decreased lymphocytes percentage (4.1%), decreased lymphocytes count (0.31 × 109/L), decreased eosinophil count (0 × 109/L)), increased C-reaction protein (170.91 mg/L), increased procalcitonin (0.45 ng/ml). Imaging examination: multiple patches, grid-like lobule and thickening of interlobular septa, typical “paving stone-like” signs. a SL(Slice): 6 mm; b high-resolution computed tomography(HRCT). HRCT. high-resolution computed tomography\nFig. 2 Typical CT / X-ray imaging manifestation (case 2). A 51 years old male with general muscle ache and fatigue for 1 week, fever for 1 day (39.1 ℃), anemia. Laboratory test: normal white blood cells (9.24 × 109/L), lymphocytes percentage (5.1%), decreased lymphocytes (0.47 × 109/ L), decreased eosinophil count (0 × 109/L), increased C-reaction protein (170.91 mg/L), increased procalcitonin (0.45 ng/ml), increased erythrocyte sedimentation rate (48 mm/h). Imaging examination: a shows patchy shadows in the outer region of the left lower lobe, b shows large ground-glass opacity in the left lower lobe, and c shows subpleural patchy ground-glass opacity in posterior part of right upper lobe and lower tongue of left upper lobe, d shows large ground-glass opacity in the basal segment of the left lower lobe\n(2) Multiple, patchy or large patches of consolidation in both lungs, with a little grid-like or honeycomb-shaped interlobular septal thickening, especially in the middle and lower lobes (Fig. 3: 26 cases, 31.3% in a total of 83 cases). It was more common in the elderly or severe condition patients.\nFig. 3 Typical CT / X-ray imaging manifestation (case 3). A 65 years old male with fever for 4 days (38.7 ℃). Laboratory test: normal white blood cells (3.72 × 109/L), decreased lymphocytes (0.9 × 109/ L), decreased eosinophil count (0 × 109/L), increased C-reaction protein (53.0 mg/L), increased procalcitonin (0.10 ng/ml), reduced liver function, hypoproteinemia, and mild anemia. Imaging examination: a and b showed large consolidation in the right middle lobe, patchy consolidation in the posterior and basal segment of the right lower lobe, with air-bronchogram inside, c showed patchy consolidation in the outer and basal segment of the left lower lobe, and a small amount of effusion in the right chest"}