PMC:6927068 / 20216-21517 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/6927068","sourcedb":"PMC","sourceid":"6927068","source_url":"https://www.ncbi.nlm.nih.gov/pmc/6927068","text":"Two trials reported the efficacy rate comparing bloodletting in the auricle to ADs, and meta-analysis from these two trials showed that there is no statistical difference between the groups in efficacy rate (RR, 0.65; 95% CI, 0.28–1.51, p=0.32; I2=0%). One trial compared bloodletting in the auricle to no intervention, and found the efficacy rate in the experimental group significantly higher than that in the control group (n=59 out of 61 patients; RR, 5.1; 95% CI 1.05–24.71; p=0.04), and also found a significant difference between the two groups in lowering both SBP (n=61 patients; MD, −8.77; 95% CI –10.20– −7.34, p\u003c0.00001) and DBP (n=61 patients; MD, −5.50; 95% CI –7.24– −3.76, p\u003c0.00001). As for the comparison of bloodletting in the auricle plus ADs versus ADs alone, three trials reported the efficacy rate, and two of them found a statistical difference between groups, one69 compared bloodletting in the auricle plus ADs to felodipine extended-release tablet or irbesartan alone (n=156 out of 178 patients; RR, 1.37; 95% CI, 1.21–1.55, p\u003c0.00001); one study67 used nifedipine in the control group (n=57 out of 60 patients; RR, 1.21; 95% CI, 1.05–1.40, p=0.009). One trial used amlodipine besylate tablets in the control group and did not find a statistical difference between groups.68","tracks":[{"project":"testtesttest","denotations":[{"id":"T92","span":{"begin":68,"end":75},"obj":"Body_part"},{"id":"T93","span":{"begin":292,"end":299},"obj":"Body_part"},{"id":"T94","span":{"begin":746,"end":753},"obj":"Body_part"},{"id":"T95","span":{"begin":920,"end":927},"obj":"Body_part"}],"attributes":[{"id":"A92","pred":"uberon_id","subj":"T92","obj":"http://purl.obolibrary.org/obo/UBERON_0001757"},{"id":"A93","pred":"uberon_id","subj":"T93","obj":"http://purl.obolibrary.org/obo/UBERON_0001757"},{"id":"A94","pred":"uberon_id","subj":"T94","obj":"http://purl.obolibrary.org/obo/UBERON_0001757"},{"id":"A95","pred":"uberon_id","subj":"T95","obj":"http://purl.obolibrary.org/obo/UBERON_0001757"},{"subj":"T92","pred":"source","obj":"testtesttest"},{"subj":"T93","pred":"source","obj":"testtesttest"},{"subj":"T94","pred":"source","obj":"testtesttest"},{"subj":"T95","pred":"source","obj":"testtesttest"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"testtesttest","color":"#93caec","default":true}]}]}}