PMC:6927068 / 15602-18418 JSONTXT

{"project":"testtesttest","denotations":[{"id":"T71","span":{"begin":10,"end":19},"obj":"Body_part"},{"id":"T72","span":{"begin":57,"end":66},"obj":"Body_part"},{"id":"T73","span":{"begin":214,"end":223},"obj":"Body_part"},{"id":"T74","span":{"begin":461,"end":470},"obj":"Body_part"},{"id":"T75","span":{"begin":514,"end":523},"obj":"Body_part"},{"id":"T76","span":{"begin":579,"end":585},"obj":"Body_part"},{"id":"T77","span":{"begin":599,"end":608},"obj":"Body_part"},{"id":"T78","span":{"begin":892,"end":901},"obj":"Body_part"},{"id":"T79","span":{"begin":1309,"end":1318},"obj":"Body_part"},{"id":"T80","span":{"begin":1388,"end":1397},"obj":"Body_part"},{"id":"T81","span":{"begin":1583,"end":1592},"obj":"Body_part"},{"id":"T82","span":{"begin":2136,"end":2145},"obj":"Body_part"},{"id":"T83","span":{"begin":2222,"end":2231},"obj":"Body_part"},{"id":"T84","span":{"begin":2301,"end":2310},"obj":"Body_part"},{"id":"T85","span":{"begin":2716,"end":2725},"obj":"Body_part"}],"attributes":[{"id":"A71","pred":"uberon_id","subj":"T71","obj":"http://purl.obolibrary.org/obo/UBERON_0001595"},{"id":"A72","pred":"uberon_id","subj":"T72","obj":"http://purl.obolibrary.org/obo/UBERON_0001595"},{"id":"A73","pred":"uberon_id","subj":"T73","obj":"http://purl.obolibrary.org/obo/UBERON_0001595"},{"id":"A74","pred":"uberon_id","subj":"T74","obj":"http://purl.obolibrary.org/obo/UBERON_0001595"},{"id":"A75","pred":"uberon_id","subj":"T75","obj":"http://purl.obolibrary.org/obo/UBERON_0001595"},{"id":"A76","pred":"uberon_id","subj":"T76","obj":"http://purl.obolibrary.org/obo/UBERON_0000467"},{"id":"A77","pred":"uberon_id","subj":"T77","obj":"http://purl.obolibrary.org/obo/UBERON_0001595"},{"id":"A78","pred":"uberon_id","subj":"T78","obj":"http://purl.obolibrary.org/obo/UBERON_0001595"},{"id":"A79","pred":"uberon_id","subj":"T79","obj":"http://purl.obolibrary.org/obo/UBERON_0001595"},{"id":"A80","pred":"uberon_id","subj":"T80","obj":"http://purl.obolibrary.org/obo/UBERON_0001595"},{"id":"A81","pred":"uberon_id","subj":"T81","obj":"http://purl.obolibrary.org/obo/UBERON_0001595"},{"id":"A82","pred":"uberon_id","subj":"T82","obj":"http://purl.obolibrary.org/obo/UBERON_0001595"},{"id":"A83","pred":"uberon_id","subj":"T83","obj":"http://purl.obolibrary.org/obo/UBERON_0001595"},{"id":"A84","pred":"uberon_id","subj":"T84","obj":"http://purl.obolibrary.org/obo/UBERON_0001595"},{"id":"A85","pred":"uberon_id","subj":"T85","obj":"http://purl.obolibrary.org/obo/UBERON_0001595"}],"text":"Effect of auricular acupressure\nAs for the comparison of auricular acupressure and sham acupoint, only one trial28 reported the efficacy rate in terms of this comparison, and found a statistical difference between auricular acupressure and sham acupoint, in favor of the experimental group (n=55 out of 60 patients; RR, 0.28; 95% CI, 0.10–0.47, p=0.003). Moreover, two trials reported the magnitude of BP change between baseline and post-intervention comparing auricular acupressure and ADs. One trial34 comparing auricular acupressure to nifedipine gastrointestinal therapeutic system (GITS) found auricular acupressure was superior to ADs in reducing SBP (n=118 patients; MD, −0.92; 95% CI, –1.09– −0.75, p\u003c0.00001), but there was no significant difference between two groups on decreasing DBP (n=118 patients; MD, −0.07; 95% CI, –0.23– −0.09, p=0.40). However, the other trial36 comparing auricular acupressure to a kind of AD (the specific medicine is unclear) showed the AD had better effect on reducing SBP (n=203 patients; MD, 2.70; 95% CI, 2.37–3.03, p\u003c0.00001) as well as on decreasing DBP (n=203 patients; MD, 2.50; 95% CI, 1.92–3.08, p\u003c0.00001). In addition, five trials reported the outcome by measuring the SBP and DBP before and after the treatment, three found a significant difference between auricular acupressure and ADs in lowering SBP after treatment, in favor of the auricular acupressure group,29,31,33 and the others did not. The data of these three trials could not be pooled due to the different kinds of ADs used in the AD groups. Four of five trials found auricular acupressure significantly effective in reducing DBP after treatment,29,31,34,37 and the data of these trials could not be pooled either due to high heterogeneity. Eight trials reported the efficacy rate by counting the number of those who had achieved BP targets after treatment. The meta-analysis from these eight trials showed that there is no statistical difference between groups in efficacy rate (n=495 out of 598 patients; RR, 0.99; 95% CI, 0.95–1.03, p=0.62; I2=0%). Furthermore, three trials reported the result from the comparison of auricular acupressure and no intervention, and found a significant difference between auricular acupressure and no intervention group in decreasing SBP, in favor of auricular acupressure,38,39,41 nevertheless the data of these trials could not be pooled due to high heterogeneity. In terms of DBP, two of three trials found a significant difference between the two groups and the other did not. Five trials reported the outcome of BP target achievement, and meta-analysis from four trials38–41 found a statistical difference between groups in achieving BP targets in favor of the auricular acupressure group (n=247 out of 238 patients; RR, 1.27; 95% CI, 1.05–1.55, p=0.02; I2=0%)."}