PMC:6723646 / 15117-15756 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/6723646","sourcedb":"PMC","sourceid":"6723646","source_url":"https://www.ncbi.nlm.nih.gov/pmc/6723646","text":"For binding assays, phages CWSYAVHPEC, YHCQGC, and DYAVHP were selected from the biopannings of mAb 1A3, and phages CEVLPGRC, CMPSVILPSC, CLDFELPGRC, CIDFDLPGRC, CGEFLPGRIC, CGDVLPSVSC, and CVSSEVLPSC were selected from the biopannings of mAb 2C7. From all of the selected phages, only phages CWSYAVHPEC and YHCQGC showed high-affinity binding for mAb 1A3, and phages CMPSVILPSC and CLDFELPGRC showed a higher affinity for mAb 2C7 (Figure S3). These phages were selected for further experiments. No high-affinity peptides isolated from the X6 library were validated, which suggested that they were too small to fit the mAb binding pockets.","tracks":[]}