PMC:6705338 / 34500-35870 JSONTXT

{"target":"http://pubannotation.org/docs/sourcedb/PMC/sourceid/6705338","sourcedb":"PMC","sourceid":"6705338","source_url":"https://www.ncbi.nlm.nih.gov/pmc/6705338","text":"Although there were no statistically significant differences among the three groups in relation to postoperative complications, it is important to note that the presence of partial dehiscence of the operative could compromise the bioincorporation process of the synthetic mesh, favoring the contamination and consequent infection of the surgical site and the implanted mesh. In the present study, the occurrence of meshoma was observed in three animals that had a partial dehiscence of operative wound and closure by second intention without the use of dressings or antibiotics. The infection of the operated site determines a prolonged inflammatory response and directly compromises the fibroplasia phase and collagen deposition, favoring the appearance of more intense adhesions, chronic infection of the mesh, retraction of the prosthesis, and appearance of meshoma28. In a clinical scenario, this outcome represents an important risk factor for complications such as visceral adhesions, chronic pain, intestinal obstruction, fistulization, hernia recurrence, and reoperations14-15. Therefore, the presence of complications related to the operative wound, such as dehiscence, favors the contamination and infection of the prosthesis, which represents an important risk factor for the failure of the synthetic mesh implant in the treatment of abdominal wall defects29.","tracks":[{"project":"2_test","denotations":[{"id":"31432994-29864263-396064","span":{"begin":868,"end":870},"obj":"29864263"},{"id":"31432994-20401733-396065","span":{"begin":1079,"end":1081},"obj":"20401733"},{"id":"31432994-29265400-396065","span":{"begin":1079,"end":1081},"obj":"29265400"},{"id":"31432994-27443425-396066","span":{"begin":1367,"end":1369},"obj":"27443425"}],"attributes":[{"subj":"31432994-29864263-396064","pred":"source","obj":"2_test"},{"subj":"31432994-20401733-396065","pred":"source","obj":"2_test"},{"subj":"31432994-29265400-396065","pred":"source","obj":"2_test"},{"subj":"31432994-27443425-396066","pred":"source","obj":"2_test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"2_test","color":"#eca993","default":true}]}]}}