PMC:6640909 / 87248-88121
Annnotations
{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/6640909","sourcedb":"PMC","sourceid":"6640909","source_url":"https://www.ncbi.nlm.nih.gov/pmc/6640909","text":"13.1 Background\nLT-MCS devices require antithrombotic therapy due to the presence of the artificial surfaces of the pump and the modified fluid dynamic pattern of the blood accompanied by shear forces. Anticoagulation for LT-MCS comprises 3 different periods: preoperative, intraoperative and early postoperative. Management is often similar to that of other cardiac surgery procedures [64]; however, some situations require specific considerations as outlined below. Each phase has distinct issues and requires specific management. Long-term antithrombotic therapy is more standardized, although patients may tread a fine line between bleeding and thrombosis. Furthermore, the optimal long-term regimen of anticoagulation should be tailored to the recipient and the device type. In this context, the development of clinical analysis tools and/or risk scores is encouraged.","divisions":[{"label":"title","span":{"begin":0,"end":15}}],"tracks":[{"project":"TEST0","denotations":[{"id":"31100109-73-79-7660","span":{"begin":387,"end":389},"obj":"[\"29029100\"]"}],"attributes":[{"subj":"31100109-73-79-7660","pred":"source","obj":"TEST0"}]},{"project":"MyTest","denotations":[{"id":"31100109-29029100-28905720","span":{"begin":387,"end":389},"obj":"29029100"}],"namespaces":[{"prefix":"_base","uri":"https://www.uniprot.org/uniprot/testbase"},{"prefix":"UniProtKB","uri":"https://www.uniprot.org/uniprot/"},{"prefix":"uniprot","uri":"https://www.uniprot.org/uniprotkb/"}],"attributes":[{"subj":"31100109-29029100-28905720","pred":"source","obj":"MyTest"}]},{"project":"0_colil","denotations":[{"id":"31100109-29029100-7660","span":{"begin":387,"end":389},"obj":"29029100"}],"attributes":[{"subj":"31100109-29029100-7660","pred":"source","obj":"0_colil"}]},{"project":"2_test","denotations":[{"id":"31100109-29029100-28905720","span":{"begin":387,"end":389},"obj":"29029100"}],"attributes":[{"subj":"31100109-29029100-28905720","pred":"source","obj":"2_test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"TEST0","color":"#93ece5","default":true},{"id":"MyTest","color":"#eccb93"},{"id":"0_colil","color":"#b193ec"},{"id":"2_test","color":"#93ec97"}]}]}}