PMC:6640909 / 123748-124458 JSONTXT

{"project":"TEST0","denotations":[{"id":"31100109-139-146-7806","span":{"begin":139,"end":142},"obj":"[\"10360727\"]"},{"id":"31100109-185-192-7807","span":{"begin":705,"end":708},"obj":"[\"28859792\"]"}],"text":"Taking care of patients with LT-MCS as a destination therapy can be more difficult than taking care of HTx candidates or HTx patients [501–504]. Factors that can complicate advanced HF management such as ageing-related comorbidities, end-organ damage, cognitive impairment, frailty and limited social support are compounded by risk of MCS failure and MCS-related complications such as bleeding, infection and stroke. As a result, LT-MCS is associated with repeated hospitalizations and a high rate of caregiver burnout. The unpredictable course of advanced HF, differences among LT-MCS devices and a limited evidence base can further complicate shared decision-making, preparedness planning and EOL care [503]."}

{"project":"MyTest","denotations":[{"id":"31100109-10360727-28905866","span":{"begin":139,"end":142},"obj":"10360727"},{"id":"31100109-28859792-28905867","span":{"begin":705,"end":708},"obj":"28859792"}],"namespaces":[{"prefix":"_base","uri":"https://www.uniprot.org/uniprot/testbase"},{"prefix":"UniProtKB","uri":"https://www.uniprot.org/uniprot/"},{"prefix":"uniprot","uri":"https://www.uniprot.org/uniprotkb/"}],"text":"Taking care of patients with LT-MCS as a destination therapy can be more difficult than taking care of HTx candidates or HTx patients [501–504]. Factors that can complicate advanced HF management such as ageing-related comorbidities, end-organ damage, cognitive impairment, frailty and limited social support are compounded by risk of MCS failure and MCS-related complications such as bleeding, infection and stroke. As a result, LT-MCS is associated with repeated hospitalizations and a high rate of caregiver burnout. The unpredictable course of advanced HF, differences among LT-MCS devices and a limited evidence base can further complicate shared decision-making, preparedness planning and EOL care [503]."}

{"project":"0_colil","denotations":[{"id":"31100109-10360727-7806","span":{"begin":139,"end":142},"obj":"10360727"},{"id":"31100109-28859792-7807","span":{"begin":705,"end":708},"obj":"28859792"}],"text":"Taking care of patients with LT-MCS as a destination therapy can be more difficult than taking care of HTx candidates or HTx patients [501–504]. Factors that can complicate advanced HF management such as ageing-related comorbidities, end-organ damage, cognitive impairment, frailty and limited social support are compounded by risk of MCS failure and MCS-related complications such as bleeding, infection and stroke. As a result, LT-MCS is associated with repeated hospitalizations and a high rate of caregiver burnout. The unpredictable course of advanced HF, differences among LT-MCS devices and a limited evidence base can further complicate shared decision-making, preparedness planning and EOL care [503]."}

{"project":"2_test","denotations":[{"id":"31100109-10360727-28905866","span":{"begin":139,"end":142},"obj":"10360727"},{"id":"31100109-28859792-28905867","span":{"begin":705,"end":708},"obj":"28859792"}],"text":"Taking care of patients with LT-MCS as a destination therapy can be more difficult than taking care of HTx candidates or HTx patients [501–504]. Factors that can complicate advanced HF management such as ageing-related comorbidities, end-organ damage, cognitive impairment, frailty and limited social support are compounded by risk of MCS failure and MCS-related complications such as bleeding, infection and stroke. As a result, LT-MCS is associated with repeated hospitalizations and a high rate of caregiver burnout. The unpredictable course of advanced HF, differences among LT-MCS devices and a limited evidence base can further complicate shared decision-making, preparedness planning and EOL care [503]."}