PMC:6640909 / 105324-106755 JSONTXT

{"project":"TEST0","denotations":[{"id":"31100109-169-176-7751","span":{"begin":212,"end":215},"obj":"[\"28674109\"]"},{"id":"31100109-113-120-7752","span":{"begin":607,"end":610},"obj":"[\"23103699\"]"},{"id":"31100109-99-106-7753","span":{"begin":712,"end":715},"obj":"[\"25220024\"]"}],"text":"Background and description of the evidence\nA total of 13% of device failures are caused by internal pump failure, whereas over 60% are caused by the failure of batteries, the controller and the peripheral cable [416]. Damage to the driveline that interferes with the operation of the pump is a rare, but life-threatening complication. It is often caused by fracture due to accidental mechanical impact. Continuous stress on the cable due to growing body size with weight gain is a risk factor. Moreover, accidental pulling of the cable by dropping the controller bag or by patient falls risks cable damage [417]. Intentional cutting or disconnection of the driveline from the controller has also been described [418]. Treatment of the majority of lead fractures is a simple repair. If the damaged driveline cannot not be repaired, it could require pump explant or exchange, high-urgency HTx, or it could result in patient death.\nPump malfunction is mainly a consequence of pump thrombosis, but technical failure of the broader system components, including the controller, the batteries and the connectors does occur. Technical failure of pulsatile pneumatically driven assist devices has a higher incidence than that of CF-LVADs. Briefly, stoppage of a TAH pump due to membrane rupture is a fatal event; Berlin Heart EXCOR allows substitution of the failing external component but not restarting of the pump in case of a pump stop."}

{"project":"MyTest","denotations":[{"id":"31100109-28674109-28905811","span":{"begin":212,"end":215},"obj":"28674109"},{"id":"31100109-23103699-28905812","span":{"begin":607,"end":610},"obj":"23103699"},{"id":"31100109-25220024-28905813","span":{"begin":712,"end":715},"obj":"25220024"}],"namespaces":[{"prefix":"_base","uri":"https://www.uniprot.org/uniprot/testbase"},{"prefix":"UniProtKB","uri":"https://www.uniprot.org/uniprot/"},{"prefix":"uniprot","uri":"https://www.uniprot.org/uniprotkb/"}],"text":"Background and description of the evidence\nA total of 13% of device failures are caused by internal pump failure, whereas over 60% are caused by the failure of batteries, the controller and the peripheral cable [416]. Damage to the driveline that interferes with the operation of the pump is a rare, but life-threatening complication. It is often caused by fracture due to accidental mechanical impact. Continuous stress on the cable due to growing body size with weight gain is a risk factor. Moreover, accidental pulling of the cable by dropping the controller bag or by patient falls risks cable damage [417]. Intentional cutting or disconnection of the driveline from the controller has also been described [418]. Treatment of the majority of lead fractures is a simple repair. If the damaged driveline cannot not be repaired, it could require pump explant or exchange, high-urgency HTx, or it could result in patient death.\nPump malfunction is mainly a consequence of pump thrombosis, but technical failure of the broader system components, including the controller, the batteries and the connectors does occur. Technical failure of pulsatile pneumatically driven assist devices has a higher incidence than that of CF-LVADs. Briefly, stoppage of a TAH pump due to membrane rupture is a fatal event; Berlin Heart EXCOR allows substitution of the failing external component but not restarting of the pump in case of a pump stop."}

{"project":"0_colil","denotations":[{"id":"31100109-28674109-7751","span":{"begin":212,"end":215},"obj":"28674109"},{"id":"31100109-23103699-7752","span":{"begin":607,"end":610},"obj":"23103699"},{"id":"31100109-25220024-7753","span":{"begin":712,"end":715},"obj":"25220024"}],"text":"Background and description of the evidence\nA total of 13% of device failures are caused by internal pump failure, whereas over 60% are caused by the failure of batteries, the controller and the peripheral cable [416]. Damage to the driveline that interferes with the operation of the pump is a rare, but life-threatening complication. It is often caused by fracture due to accidental mechanical impact. Continuous stress on the cable due to growing body size with weight gain is a risk factor. Moreover, accidental pulling of the cable by dropping the controller bag or by patient falls risks cable damage [417]. Intentional cutting or disconnection of the driveline from the controller has also been described [418]. Treatment of the majority of lead fractures is a simple repair. If the damaged driveline cannot not be repaired, it could require pump explant or exchange, high-urgency HTx, or it could result in patient death.\nPump malfunction is mainly a consequence of pump thrombosis, but technical failure of the broader system components, including the controller, the batteries and the connectors does occur. Technical failure of pulsatile pneumatically driven assist devices has a higher incidence than that of CF-LVADs. Briefly, stoppage of a TAH pump due to membrane rupture is a fatal event; Berlin Heart EXCOR allows substitution of the failing external component but not restarting of the pump in case of a pump stop."}

{"project":"2_test","denotations":[{"id":"31100109-28674109-28905811","span":{"begin":212,"end":215},"obj":"28674109"},{"id":"31100109-23103699-28905812","span":{"begin":607,"end":610},"obj":"23103699"},{"id":"31100109-25220024-28905813","span":{"begin":712,"end":715},"obj":"25220024"}],"text":"Background and description of the evidence\nA total of 13% of device failures are caused by internal pump failure, whereas over 60% are caused by the failure of batteries, the controller and the peripheral cable [416]. Damage to the driveline that interferes with the operation of the pump is a rare, but life-threatening complication. It is often caused by fracture due to accidental mechanical impact. Continuous stress on the cable due to growing body size with weight gain is a risk factor. Moreover, accidental pulling of the cable by dropping the controller bag or by patient falls risks cable damage [417]. Intentional cutting or disconnection of the driveline from the controller has also been described [418]. Treatment of the majority of lead fractures is a simple repair. If the damaged driveline cannot not be repaired, it could require pump explant or exchange, high-urgency HTx, or it could result in patient death.\nPump malfunction is mainly a consequence of pump thrombosis, but technical failure of the broader system components, including the controller, the batteries and the connectors does occur. Technical failure of pulsatile pneumatically driven assist devices has a higher incidence than that of CF-LVADs. Briefly, stoppage of a TAH pump due to membrane rupture is a fatal event; Berlin Heart EXCOR allows substitution of the failing external component but not restarting of the pump in case of a pump stop."}