PMC:6610377 / 17619-18722 JSONTXT

{"project":"MyTest","denotations":[{"id":"30838920-21493128-28639299","span":{"begin":88,"end":91},"obj":"21493128"},{"id":"30838920-11884353-28639300","span":{"begin":509,"end":512},"obj":"11884353"},{"id":"30838920-22036962-28639301","span":{"begin":556,"end":559},"obj":"22036962"},{"id":"30838920-25589668-28639302","span":{"begin":901,"end":904},"obj":"25589668"}],"namespaces":[{"prefix":"_base","uri":"https://www.uniprot.org/uniprot/testbase"},{"prefix":"UniProtKB","uri":"https://www.uniprot.org/uniprot/"},{"prefix":"uniprot","uri":"https://www.uniprot.org/uniprotkb/"}],"text":"Somatosensory sensations represented the majority (n = 335, 61%) of all evoked symptoms.44 Paresthesias were most frequent (Figure 4.1A), followed by thermal sensations. Thermal responses were evoked by stimulation around the central sulcus of the insula (Figure 4.1B). Painful sensations were elicited mostly from the posterior third of the insula and described as burning, electric shock, painful pins, or cramps (Figure 4.1C). Painful responses to insular stimulation were first observed by Ostrowsky et al45 and then further confirmed by Mazzola et al.46 This later study showed that painful responses were rare (60 of \u003e4000 stimulations) and were only elicited by insular and secondary somatosensory cortex (SII) stimulations. They were never observed when stimulating primary somatosensory cortex (SI) or any other cortical area. These results are in line with the SEEG study of Montavont et al,12 in which the insula or SII was systematically involved at seizure onset in all 5 patients suffering from painful seizures and in which ictal pain was reproduced by the stimulation of these 2 regions."}

{"project":"0_colil","denotations":[{"id":"30838920-21493128-1150","span":{"begin":88,"end":90},"obj":"21493128"},{"id":"30838920-11884353-1151","span":{"begin":509,"end":511},"obj":"11884353"},{"id":"30838920-22036962-1152","span":{"begin":556,"end":558},"obj":"22036962"},{"id":"30838920-25589668-1153","span":{"begin":901,"end":903},"obj":"25589668"}],"text":"Somatosensory sensations represented the majority (n = 335, 61%) of all evoked symptoms.44 Paresthesias were most frequent (Figure 4.1A), followed by thermal sensations. Thermal responses were evoked by stimulation around the central sulcus of the insula (Figure 4.1B). Painful sensations were elicited mostly from the posterior third of the insula and described as burning, electric shock, painful pins, or cramps (Figure 4.1C). Painful responses to insular stimulation were first observed by Ostrowsky et al45 and then further confirmed by Mazzola et al.46 This later study showed that painful responses were rare (60 of \u003e4000 stimulations) and were only elicited by insular and secondary somatosensory cortex (SII) stimulations. They were never observed when stimulating primary somatosensory cortex (SI) or any other cortical area. These results are in line with the SEEG study of Montavont et al,12 in which the insula or SII was systematically involved at seizure onset in all 5 patients suffering from painful seizures and in which ictal pain was reproduced by the stimulation of these 2 regions."}

{"project":"2_test","denotations":[{"id":"30838920-21493128-28639299","span":{"begin":88,"end":90},"obj":"21493128"},{"id":"30838920-11884353-28639300","span":{"begin":509,"end":511},"obj":"11884353"},{"id":"30838920-22036962-28639301","span":{"begin":556,"end":558},"obj":"22036962"},{"id":"30838920-25589668-28639302","span":{"begin":901,"end":903},"obj":"25589668"}],"text":"Somatosensory sensations represented the majority (n = 335, 61%) of all evoked symptoms.44 Paresthesias were most frequent (Figure 4.1A), followed by thermal sensations. Thermal responses were evoked by stimulation around the central sulcus of the insula (Figure 4.1B). Painful sensations were elicited mostly from the posterior third of the insula and described as burning, electric shock, painful pins, or cramps (Figure 4.1C). Painful responses to insular stimulation were first observed by Ostrowsky et al45 and then further confirmed by Mazzola et al.46 This later study showed that painful responses were rare (60 of \u003e4000 stimulations) and were only elicited by insular and secondary somatosensory cortex (SII) stimulations. They were never observed when stimulating primary somatosensory cortex (SI) or any other cortical area. These results are in line with the SEEG study of Montavont et al,12 in which the insula or SII was systematically involved at seizure onset in all 5 patients suffering from painful seizures and in which ictal pain was reproduced by the stimulation of these 2 regions."}

{"project":"testtesttest","denotations":[{"id":"T138","span":{"begin":226,"end":254},"obj":"Body_part"},{"id":"T139","span":{"begin":319,"end":328},"obj":"Body_part"},{"id":"T140","span":{"begin":342,"end":348},"obj":"Body_part"},{"id":"T141","span":{"begin":681,"end":711},"obj":"Body_part"},{"id":"T143","span":{"begin":774,"end":802},"obj":"Body_part"},{"id":"T144","span":{"begin":917,"end":923},"obj":"Body_part"}],"attributes":[{"id":"A138","pred":"uberon_id","subj":"T138","obj":"http://purl.obolibrary.org/obo/UBERON_0035925"},{"id":"A139","pred":"uberon_id","subj":"T139","obj":"http://purl.obolibrary.org/obo/UBERON_0001353"},{"id":"A140","pred":"uberon_id","subj":"T140","obj":"http://purl.obolibrary.org/obo/UBERON_0002022"},{"id":"A141","pred":"uberon_id","subj":"T141","obj":"http://purl.obolibrary.org/obo/UBERON_0006471"},{"id":"A142","pred":"uberon_id","subj":"T141","obj":"http://purl.obolibrary.org/obo/UBERON_0008934"},{"id":"A143","pred":"uberon_id","subj":"T143","obj":"http://purl.obolibrary.org/obo/UBERON_0008933"},{"id":"A144","pred":"uberon_id","subj":"T144","obj":"http://purl.obolibrary.org/obo/UBERON_0002022"}],"text":"Somatosensory sensations represented the majority (n = 335, 61%) of all evoked symptoms.44 Paresthesias were most frequent (Figure 4.1A), followed by thermal sensations. Thermal responses were evoked by stimulation around the central sulcus of the insula (Figure 4.1B). Painful sensations were elicited mostly from the posterior third of the insula and described as burning, electric shock, painful pins, or cramps (Figure 4.1C). Painful responses to insular stimulation were first observed by Ostrowsky et al45 and then further confirmed by Mazzola et al.46 This later study showed that painful responses were rare (60 of \u003e4000 stimulations) and were only elicited by insular and secondary somatosensory cortex (SII) stimulations. They were never observed when stimulating primary somatosensory cortex (SI) or any other cortical area. These results are in line with the SEEG study of Montavont et al,12 in which the insula or SII was systematically involved at seizure onset in all 5 patients suffering from painful seizures and in which ictal pain was reproduced by the stimulation of these 2 regions."}