PMC:6610326 / 22877-23754 JSONTXT

{"project":"2_test","denotations":[{"id":"31316328-21727215-38515381","span":{"begin":500,"end":504},"obj":"21727215"},{"id":"31316328-2771042-38515382","span":{"begin":517,"end":521},"obj":"2771042"},{"id":"31316328-25107988-38515383","span":{"begin":544,"end":548},"obj":"25107988"},{"id":"31316328-4107849-38515384","span":{"begin":567,"end":571},"obj":"4107849"},{"id":"31316328-4148753-38515385","span":{"begin":595,"end":599},"obj":"4148753"},{"id":"31316328-8600170-38515386","span":{"begin":611,"end":615},"obj":"8600170"},{"id":"31316328-2934267-38515387","span":{"begin":638,"end":642},"obj":"2934267"},{"id":"31316328-4985725-38515388","span":{"begin":657,"end":661},"obj":"4985725"},{"id":"31316328-2466962-38515389","span":{"begin":680,"end":684},"obj":"2466962"},{"id":"31316328-22570384-38515390","span":{"begin":713,"end":717},"obj":"22570384"},{"id":"31316328-10578106-38515391","span":{"begin":742,"end":746},"obj":"10578106"},{"id":"31316328-20826431-38515392","span":{"begin":768,"end":772},"obj":"20826431"},{"id":"31316328-22485182-38515393","span":{"begin":793,"end":797},"obj":"22485182"},{"id":"31316328-26502195-38515394","span":{"begin":818,"end":822},"obj":"26502195"},{"id":"31316328-3372722-38515395","span":{"begin":846,"end":850},"obj":"3372722"},{"id":"31316328-4261815-38515396","span":{"begin":871,"end":875},"obj":"4261815"}],"text":"Table 4 Comparison of α-spinal motor neurons and oculomotor neurons.\nSpinal α-MN Oculomotor neuron\nTarget muscle fiber Single fiber type1 Multiple fiber types1\nSoma size Larger2,3 Smaller2,3\nDendrite branching Larger2 Smaller2\nMotor unit size (innervation ratio) Larger4,5,6,7 Smaller4,5,6,7\nResting potential Smaller8,9,10 Higher8,9,10\nDischarge frequency 100 Hz8,9,10 100–600 Hz8,9,10\nAffected in ALS Yes11,12,13,14 No11,12,13,14\nAffected in aging Yes15,16 No15,16\n1(Zhou et al., 2011), 2(Durand, 1989), 3(Shoenfeld et al., 2014), 4(Burke et al., 1971), 5(Burke and Tsairis, 1973), 6(Enoka, 1995), 7(Guéritaud et al., 1985), 8(Robinson, 1970), 9(Fuchs et al., 1988), 10(Torres-Torrelo et al., 2012), 11(Nimchinsky et al., 2000), 12(Hedlund et al., 2010), 13(Valdez et al., 2012), 14(Comley et al., 2016), 15(Hashizume et al., 1988), 16(Swash and Fox, 1972)."}

{"project":"0_colil","denotations":[{"id":"31316328-21727215-630838","span":{"begin":500,"end":504},"obj":"21727215"},{"id":"31316328-2771042-630839","span":{"begin":517,"end":521},"obj":"2771042"},{"id":"31316328-25107988-630840","span":{"begin":544,"end":548},"obj":"25107988"},{"id":"31316328-4107849-630841","span":{"begin":567,"end":571},"obj":"4107849"},{"id":"31316328-4148753-630842","span":{"begin":595,"end":599},"obj":"4148753"},{"id":"31316328-8600170-630843","span":{"begin":611,"end":615},"obj":"8600170"},{"id":"31316328-2934267-630844","span":{"begin":638,"end":642},"obj":"2934267"},{"id":"31316328-4985725-630845","span":{"begin":657,"end":661},"obj":"4985725"},{"id":"31316328-2466962-630846","span":{"begin":680,"end":684},"obj":"2466962"},{"id":"31316328-22570384-630847","span":{"begin":713,"end":717},"obj":"22570384"},{"id":"31316328-10578106-630848","span":{"begin":742,"end":746},"obj":"10578106"},{"id":"31316328-20826431-630849","span":{"begin":768,"end":772},"obj":"20826431"},{"id":"31316328-22485182-630850","span":{"begin":793,"end":797},"obj":"22485182"},{"id":"31316328-26502195-630851","span":{"begin":818,"end":822},"obj":"26502195"},{"id":"31316328-3372722-630852","span":{"begin":846,"end":850},"obj":"3372722"},{"id":"31316328-4261815-630853","span":{"begin":871,"end":875},"obj":"4261815"}],"text":"Table 4 Comparison of α-spinal motor neurons and oculomotor neurons.\nSpinal α-MN Oculomotor neuron\nTarget muscle fiber Single fiber type1 Multiple fiber types1\nSoma size Larger2,3 Smaller2,3\nDendrite branching Larger2 Smaller2\nMotor unit size (innervation ratio) Larger4,5,6,7 Smaller4,5,6,7\nResting potential Smaller8,9,10 Higher8,9,10\nDischarge frequency 100 Hz8,9,10 100–600 Hz8,9,10\nAffected in ALS Yes11,12,13,14 No11,12,13,14\nAffected in aging Yes15,16 No15,16\n1(Zhou et al., 2011), 2(Durand, 1989), 3(Shoenfeld et al., 2014), 4(Burke et al., 1971), 5(Burke and Tsairis, 1973), 6(Enoka, 1995), 7(Guéritaud et al., 1985), 8(Robinson, 1970), 9(Fuchs et al., 1988), 10(Torres-Torrelo et al., 2012), 11(Nimchinsky et al., 2000), 12(Hedlund et al., 2010), 13(Valdez et al., 2012), 14(Comley et al., 2016), 15(Hashizume et al., 1988), 16(Swash and Fox, 1972)."}