PMC:6610326 / 18915-20452 JSONTXT

{"project":"2_test","denotations":[{"id":"31316328-4148752-38515348","span":{"begin":919,"end":923},"obj":"4148752"},{"id":"31316328-7459634-38515349","span":{"begin":951,"end":955},"obj":"7459634"},{"id":"31316328-7119171-38515350","span":{"begin":974,"end":978},"obj":"7119171"},{"id":"31316328-3819010-38515351","span":{"begin":1000,"end":1004},"obj":"3819010"},{"id":"31316328-24381813-38515352","span":{"begin":1025,"end":1029},"obj":"24381813"},{"id":"31316328-25385594-38515353","span":{"begin":1053,"end":1057},"obj":"25385594"},{"id":"31316328-874534-38515354","span":{"begin":1076,"end":1080},"obj":"874534"},{"id":"31316328-29502344-38515355","span":{"begin":1103,"end":1107},"obj":"29502344"},{"id":"31316328-7298916-38515356","span":{"begin":1134,"end":1138},"obj":"7298916"},{"id":"31316328-4148753-38515357","span":{"begin":1163,"end":1167},"obj":"4148753"},{"id":"31316328-8246185-38515358","span":{"begin":1193,"end":1197},"obj":"8246185"},{"id":"31316328-8492155-38515359","span":{"begin":1213,"end":1217},"obj":"8492155"},{"id":"31316328-3839011-38515360","span":{"begin":1238,"end":1242},"obj":"3839011"},{"id":"31316328-13430719-38515361","span":{"begin":1263,"end":1267},"obj":"13430719"},{"id":"31316328-2987433-38515362","span":{"begin":1290,"end":1294},"obj":"2987433"},{"id":"31316328-10729333-38515363","span":{"begin":1313,"end":1317},"obj":"10729333"},{"id":"31316328-17766128-38515364","span":{"begin":1339,"end":1343},"obj":"17766128"},{"id":"31316328-16474388-38515365","span":{"begin":1361,"end":1365},"obj":"16474388"},{"id":"31316328-3372722-38515366","span":{"begin":1389,"end":1393},"obj":"3372722"},{"id":"31316328-8782115-38515367","span":{"begin":1418,"end":1422},"obj":"8782115"},{"id":"31316328-2656932-38515368","span":{"begin":1449,"end":1453},"obj":"2656932"},{"id":"31316328-20437528-38515369","span":{"begin":1473,"end":1477},"obj":"20437528"},{"id":"31316328-20843861-38515370","span":{"begin":1503,"end":1507},"obj":"20843861"},{"id":"31316328-23129791-38515371","span":{"begin":1531,"end":1535},"obj":"23129791"}],"text":"Table 3 Comparison of fast (FF, fast-fatigable; FR, fast-resistant) and slow (S) spinal α-motor neurons.\nSpinal α-MN\nF S\nTarget muscle fiber IIb (FF), IIa (FR)1 I1\nSoma size Similar2,3,4,5,6 Similar2,3,4,5,6\nAxon diameter Larger7,8 Thinner7,8\nDendrite branching More4,9 Less4,9\nMotor unit size (innervation ratio) Larger1,10 Smaller1,10\nMembrane input resistance Smaller11,12,13 Larger11,12,13\nFiring Phasic14,15 Tonic14,15\nAxon conduction velocity Faster1,13 Slower1,13\nAfterhyperpolarization duration Shorter14 Longer14\nRecruitment Late15 Early15\nAffected in ALS Early16,17,18 Late16,17,18\nAffected in aging Early19,20,21 Late19,20,21\nMarkers CHODL22 CALCA22 SV2a23 SK324 ESRRB22 (adult)\nCALCA, calcitonin-related polypeptide alpha; CHODL, chondrolectin; SV2A, synaptic vesicle glycoprotein 2a; SK3, postsynaptic Ca2+-activated K+ 3; ESRRB, estrogen-related receptor beta. 1(Burke et al., 1973), 2(Kernell and Zwaagstra, 1981), 3(Burke et al., 1982), 4(Cullheim et al., 1987), 5(Vinsant et al., 2013), 6(Hadzipasic et al., 2014), 7(Burke et al., 1977), 8(Dukkipati et al., 2018), 9(Ulfhake and Kellerth, 1981), 10(Burke and Tsairis, 1973), 11(Bakels and Kernell, 1993), 12(Gardiner, 1993), 13(Zengel et al., 1985), 14(Eccles et al., 1957), 15(Zajac and Faden, 1985), 16(Frey et al., 2000), 17(Hegedus et al., 2007), 18(Pun et al., 2006), 19(Hashizume et al., 1988), 20(Kadhiresan et al., 1996), 21(Kanda and Hashizume, 1989), 22(Enjin et al., 2010), 23(Chakkalakal et al., 2010), 24(Deardorff et al., 2013)."}

{"project":"0_colil","denotations":[{"id":"31316328-4148752-630805","span":{"begin":919,"end":923},"obj":"4148752"},{"id":"31316328-7459634-630806","span":{"begin":951,"end":955},"obj":"7459634"},{"id":"31316328-7119171-630807","span":{"begin":974,"end":978},"obj":"7119171"},{"id":"31316328-3819010-630808","span":{"begin":1000,"end":1004},"obj":"3819010"},{"id":"31316328-24381813-630809","span":{"begin":1025,"end":1029},"obj":"24381813"},{"id":"31316328-25385594-630810","span":{"begin":1053,"end":1057},"obj":"25385594"},{"id":"31316328-874534-630811","span":{"begin":1076,"end":1080},"obj":"874534"},{"id":"31316328-29502344-630812","span":{"begin":1103,"end":1107},"obj":"29502344"},{"id":"31316328-7298916-630813","span":{"begin":1134,"end":1138},"obj":"7298916"},{"id":"31316328-4148753-630814","span":{"begin":1163,"end":1167},"obj":"4148753"},{"id":"31316328-8246185-630815","span":{"begin":1193,"end":1197},"obj":"8246185"},{"id":"31316328-8492155-630816","span":{"begin":1213,"end":1217},"obj":"8492155"},{"id":"31316328-3839011-630817","span":{"begin":1238,"end":1242},"obj":"3839011"},{"id":"31316328-13430719-630818","span":{"begin":1263,"end":1267},"obj":"13430719"},{"id":"31316328-2987433-630819","span":{"begin":1290,"end":1294},"obj":"2987433"},{"id":"31316328-10729333-630820","span":{"begin":1313,"end":1317},"obj":"10729333"},{"id":"31316328-17766128-630821","span":{"begin":1339,"end":1343},"obj":"17766128"},{"id":"31316328-16474388-630822","span":{"begin":1361,"end":1365},"obj":"16474388"},{"id":"31316328-3372722-630823","span":{"begin":1389,"end":1393},"obj":"3372722"},{"id":"31316328-8782115-630824","span":{"begin":1418,"end":1422},"obj":"8782115"},{"id":"31316328-2656932-630825","span":{"begin":1449,"end":1453},"obj":"2656932"},{"id":"31316328-20437528-630826","span":{"begin":1473,"end":1477},"obj":"20437528"},{"id":"31316328-20843861-630827","span":{"begin":1503,"end":1507},"obj":"20843861"},{"id":"31316328-23129791-630828","span":{"begin":1531,"end":1535},"obj":"23129791"}],"text":"Table 3 Comparison of fast (FF, fast-fatigable; FR, fast-resistant) and slow (S) spinal α-motor neurons.\nSpinal α-MN\nF S\nTarget muscle fiber IIb (FF), IIa (FR)1 I1\nSoma size Similar2,3,4,5,6 Similar2,3,4,5,6\nAxon diameter Larger7,8 Thinner7,8\nDendrite branching More4,9 Less4,9\nMotor unit size (innervation ratio) Larger1,10 Smaller1,10\nMembrane input resistance Smaller11,12,13 Larger11,12,13\nFiring Phasic14,15 Tonic14,15\nAxon conduction velocity Faster1,13 Slower1,13\nAfterhyperpolarization duration Shorter14 Longer14\nRecruitment Late15 Early15\nAffected in ALS Early16,17,18 Late16,17,18\nAffected in aging Early19,20,21 Late19,20,21\nMarkers CHODL22 CALCA22 SV2a23 SK324 ESRRB22 (adult)\nCALCA, calcitonin-related polypeptide alpha; CHODL, chondrolectin; SV2A, synaptic vesicle glycoprotein 2a; SK3, postsynaptic Ca2+-activated K+ 3; ESRRB, estrogen-related receptor beta. 1(Burke et al., 1973), 2(Kernell and Zwaagstra, 1981), 3(Burke et al., 1982), 4(Cullheim et al., 1987), 5(Vinsant et al., 2013), 6(Hadzipasic et al., 2014), 7(Burke et al., 1977), 8(Dukkipati et al., 2018), 9(Ulfhake and Kellerth, 1981), 10(Burke and Tsairis, 1973), 11(Bakels and Kernell, 1993), 12(Gardiner, 1993), 13(Zengel et al., 1985), 14(Eccles et al., 1957), 15(Zajac and Faden, 1985), 16(Frey et al., 2000), 17(Hegedus et al., 2007), 18(Pun et al., 2006), 19(Hashizume et al., 1988), 20(Kadhiresan et al., 1996), 21(Kanda and Hashizume, 1989), 22(Enjin et al., 2010), 23(Chakkalakal et al., 2010), 24(Deardorff et al., 2013)."}