PMC:6582309 / 32060-32636
Annnotations
{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/6582309","sourcedb":"PMC","sourceid":"6582309","source_url":"https://www.ncbi.nlm.nih.gov/pmc/6582309","text":"TABLE 2 Pathological hallmarks of CCD and/or AD.\nAbnormality CCD AD\nCognitive decline + +\nBrain atrophy + +\nNeuronal damage and death + +\nAβ accumulation in brain parenchyma + +\nDiffuse Aβ plaques + +\nDense-core Aβ plaques − +\nAβ accumulation in blood vessel walls (CAA) + +\nNeurofibrillary tangles (NTFs) formation − +\nMicroglial dysfunction + +\nAstrocyte dysfunction + +\nAstroglial hypertrophy and hyperplasia + +\nOxidative brain damage + +\nMitochondrial dysfunction + +\nCholinergic dysfunction + +\nImpaired neuronal glucose metabolism + +","divisions":[{"label":"label","span":{"begin":0,"end":7}},{"label":"caption","span":{"begin":9,"end":49}},{"label":"p","span":{"begin":9,"end":49}},{"label":"tr","span":{"begin":50,"end":72}},{"label":"td","span":{"begin":50,"end":62}},{"label":"td","span":{"begin":63,"end":67}},{"label":"td","span":{"begin":69,"end":72}},{"label":"tr","span":{"begin":73,"end":96}},{"label":"td","span":{"begin":73,"end":90}},{"label":"td","span":{"begin":92,"end":93}},{"label":"td","span":{"begin":95,"end":96}},{"label":"tr","span":{"begin":97,"end":116}},{"label":"td","span":{"begin":97,"end":110}},{"label":"td","span":{"begin":112,"end":113}},{"label":"td","span":{"begin":115,"end":116}},{"label":"tr","span":{"begin":117,"end":148}},{"label":"td","span":{"begin":117,"end":142}},{"label":"td","span":{"begin":144,"end":145}},{"label":"td","span":{"begin":147,"end":148}},{"label":"tr","span":{"begin":149,"end":190}},{"label":"td","span":{"begin":149,"end":184}},{"label":"td","span":{"begin":186,"end":187}},{"label":"td","span":{"begin":189,"end":190}},{"label":"tr","span":{"begin":191,"end":215}},{"label":"td","span":{"begin":191,"end":209}},{"label":"td","span":{"begin":211,"end":212}},{"label":"td","span":{"begin":214,"end":215}},{"label":"tr","span":{"begin":216,"end":243}},{"label":"td","span":{"begin":216,"end":237}},{"label":"td","span":{"begin":239,"end":240}},{"label":"td","span":{"begin":242,"end":243}},{"label":"tr","span":{"begin":244,"end":293}},{"label":"td","span":{"begin":244,"end":287}},{"label":"td","span":{"begin":289,"end":290}},{"label":"td","span":{"begin":292,"end":293}},{"label":"tr","span":{"begin":294,"end":340}},{"label":"td","span":{"begin":294,"end":334}},{"label":"td","span":{"begin":336,"end":337}},{"label":"td","span":{"begin":339,"end":340}},{"label":"tr","span":{"begin":341,"end":369}},{"label":"td","span":{"begin":341,"end":363}},{"label":"td","span":{"begin":365,"end":366}},{"label":"td","span":{"begin":368,"end":369}},{"label":"tr","span":{"begin":370,"end":397}},{"label":"td","span":{"begin":370,"end":391}},{"label":"td","span":{"begin":393,"end":394}},{"label":"td","span":{"begin":396,"end":397}},{"label":"tr","span":{"begin":398,"end":442}},{"label":"td","span":{"begin":398,"end":436}},{"label":"td","span":{"begin":438,"end":439}},{"label":"td","span":{"begin":441,"end":442}},{"label":"tr","span":{"begin":443,"end":471}},{"label":"td","span":{"begin":443,"end":465}},{"label":"td","span":{"begin":467,"end":468}},{"label":"td","span":{"begin":470,"end":471}},{"label":"tr","span":{"begin":472,"end":503}},{"label":"td","span":{"begin":472,"end":497}},{"label":"td","span":{"begin":499,"end":500}},{"label":"td","span":{"begin":502,"end":503}},{"label":"tr","span":{"begin":504,"end":533}},{"label":"td","span":{"begin":504,"end":527}},{"label":"td","span":{"begin":529,"end":530}},{"label":"td","span":{"begin":532,"end":533}},{"label":"td","span":{"begin":534,"end":570}},{"label":"td","span":{"begin":572,"end":573}}],"tracks":[]}